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Comparative analysis of proteome and transcriptome variation in mouse.
Published 2011-06-01“…We have examined this issue using a genetic approach in which natural variations were used to perturb both transcript levels and protein levels among inbred strains of mice. …”
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Inference of cell type content from human brain transcriptomic datasets illuminates the effects of age, manner of death, dissection, and psychiatric diagnosis.
Published 2018-01-01“…Using this database, we predicted the relative cell type content for 833 human cortical samples using microarray or RNA-Seq data from the Pritzker Consortium (GSE92538) or publicly-available databases (GSE53987, GSE21935, GSE21138, CommonMind Consortium). …”
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Identification and Validation of Aging-Related Genes in IgA Nephropathy in the Asian Population
Published 2025-07-01Get full text
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Enhanced leukemia prediction using hybrid ant colony and ant lion optimization for gene selection and classification
Published 2025-06-01“…Gene selection plays a crucial role in the pre-processing of microarray data, aiming to identify a small set of genes that enhances classification accuracy and reduces costs. …”
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Global Trends and Emerging Frontiers on Ovarian Endometriosis: A Bibliometric and Visualization Analysis
Published 2025-06-01Get full text
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46
Genome-Wide Association Study of Exercise Addiction Among Elite Wrestlers
Published 2025-01-01“…Whole-genome genotyping was performed using DNA microarray. Results: Using a genome-wide approach (<i>p</i> < 1.0 × 10<sup>−</sup>⁵), we identified six suggestively significant single-nucleotide polymorphisms (SNPs) associated with exercise addiction status. …”
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Transcriptomic analysis of laser-capture microdissected tumors reveals RAD51AP1 as a tumor-specific marker associated progression from pancreatic intraepithelial neoplasia to invas...
Published 2025-06-01“…Immunohistochemistry (IHC) on 353 PDAC patients, including 73 PanIN lesions and 280 tumor tissues on tissue microarray (TMA) slides, provided further confirmation. …”
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Bayesian weighted random forest for classification of high-dimensional genomics data
Published 2023-10-01“…Secondly, a new variable ranking procedure is developed and then hybridized with BWRCF to tackle the high-dimensionality issues. The performance of the proposed method is analyzed using simulated and real-life high-dimensional microarray datasets based on holdout accuracy and misclassification error rates. …”
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Machine learning reveals CAT gene as a novel potential diagnostic and prognostic biomarker in non-small cell lung cancer
Published 2024-12-01“…Herein, we would apply machine learning methods to specifically analyze the issue of biomarker applicability across different age groups in NSCLC. …”
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51
Delineation of 2q32q35 Deletion Phenotypes: Two Apparent “Proximal” and “Distal” Syndromes
Published 2013-01-01“…They presented with wide-ranging phenotypic variation including facial dysmorphisms, cleft palate, learning difficulties, behavioural issues and severe heart defects. Microarray analysis confirmed an 8.6 Mb deletion in patients 1 and 2 and a 24.7 Mb deletion in patient 3. …”
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c-Triadem: A constrained, explainable deep learning model to identify novel biomarkers in Alzheimer's disease.
Published 2025-01-01“…We trained the model with blood genotyping data, microarray, and clinical features from the Alzheimer's Neuroimaging Disease Initiative (ADNI). …”
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53
Silencing NEDD4L Effectively Inhibits the Malignant Behaviors of Hepatocellular Carcinoma
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Deciphering cholangiocarcinoma heterogeneity and specific progenitor cell niche of extrahepatic cholangiocarcinoma at single-cell resolution
Published 2025-06-01“…We aim to address this issue using single-cell and spatially resolved transcriptomic approaches. …”
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Identification of Novel Biomarkers in Huntington’s Disease Based on Differential Gene Expression Meta-Analysis and Machine Learning Approach
Published 2025-07-01“…Currently, the diagnosis relies on the signs and symptoms shown by patients; however, by that stage, the psychomotor issues have progressed to a point where reversal of the condition is unattainable. …”
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Reclassification of Variants Following Renal Genetics Testing: Uncommon Yet Impactful for Diagnosis and Management
Published 2024-05-01“…Twenty amendments were issued across 19 pedigrees involving 19 variants in 17 genes. …”
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Evaluating Biocompatibility: From Classical Techniques to State-of-the-Art Functional Proteomics
Published 2025-07-01“…Biocompatibility remains a central issue for introducing biomaterials and nanomedicines into the clinic, requiring safety, functionality, toxicity prevention, and the control of foreign body reactions. …”
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Integrated analyses of copy number variations and gene expression in lung adenocarcinoma.
Published 2011-01-01“…Identification of prognostic biomarkers for lung cancer using gene expression microarrays poses a major challenge in that very few overlapping genes have been reported among different studies. …”
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Cost-effective solutions for high-throughput enzymatic DNA methylation sequencing.
Published 2025-05-01“…., assays that rely on microarrays, enzyme digests, or sequence capture to target a subset of the genome). …”
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