Machine learning for detection of diffusion abnormalities-related respiratory changes among normal, overweight, and obese individuals based on BMI and pulmonary ventilation paramet... by Xin-Yue Song, Xin-Peng Xie, Wen-Jing Xu, Yu-Jia Cao, Bin-Miao Liang

“…We evaluated the effectiveness of various supervised ML algorithms and identified the optimal configurations for these applications. …”
Get full text

HOW I TREAT PH+ ACUTE LYMPHOBLASTIC LEUKEMIA by Robin Foà

“…I have been asked to cover ‘How I Treat Ph+ALL’, which more appropriately should be ‘How Should I Treat Ph+ LL’ Based on the 25-year experience gathered through the GIMEMA trials, the optimal algorithm should be: i) Identify the presence of the BCR/ABL gene lesion within one week from diagnosis; ii) During this time treat patients with steroids; iii) Start induction with dasatinib or ponatinib plus steroids, with no systemic chemotherapy; iv) CNS prophylaxis should be carried out; v) MRD should be monitored molecularly at given timepoints; vi) After induction, all patients should be consolidated with multiple cycles of blinatumomab (up to 5 in our protocols); vii) TKI should not be stopped. …”
Get full text

Evaluating the Accuracy and Reliability of Real-World Digital Mobility Outcomes in Older Adults After Hip Fracture: Cross-Sectional Observational Study by Martin A Berge, Anisoara Paraschiv-Ionescu, Cameron Kirk, Arne Küderle, Encarna Micó-Amigo, Clemens Becker, Andrea Cereatti, Silvia Del Din, Monika Engdal, Judith Garcia-Aymerich, Karoline B Grønvik, Clint Hansen, Jeffrey M Hausdorff, Jorunn L Helbostad, Carl-Philipp Jansen, Lars Gunnar Johnsen, Jochen Klenk, Sarah Koch, Walter Maetzler, Dimitrios Megaritis, Arne Müller, Lynn Rochester, Lars Schwickert, Kristin Taraldsen, Beatrix Vereijken

“…Accuracy and reliability of most DMOs improved when excluding WBs of <10 seconds and were higher for WBs of >30 seconds than for WBs of 10 to 30 seconds and for participants with higher physical function. …”
Get full text

Validation of Sea Surface Temperature From GK-2A Geostationary Satellite and Error Reduction Considering Impact of Satellite Zenith Angle by Kyung-Ae Park, Hye-Jin Woo, Stephane Saux Picart, Anne O'Carroll, Eunha Sohn, HuiTae Joo, Joon-Soo Lee, Joon-Yong Yang

“…By proposing optimal algorithms for SST retrievals from geostationary satellites, this study is anticipated to improve the monitoring of SSTs in regions covered by GK-2A. …”
Get full text

Digital augmentation of aftercare for patients with anorexia nervosa: the TRIANGLE RCT and economic evaluation by Janet Treasure, Katie Rowlands, Valentina Cardi, Suman Ambwani, David McDaid, Jodie Lord, Danielle Clark Bryan, Pamela Macdonald, Eva Bonin, Ulrike Schmidt, Jon Arcelus, Amy Harrison, Sabine Landau

“…From the health system and societal perspectives, there is an 11.5% and 25% probability of being cost-effective at a willingness-to-pay threshold of £20,000 per QALY gained. Over time, most outcome variables improved, although patients remained symptomatic. …”
Get full text

A Distributed Collaborative Navigation Strategy Based on Adaptive Extended Kalman Filter Integrated Positioning and Model Predictive Control for Global Navigation Satellite System/... by Wanqiang Chen, Yunpeng Jing, Shuo Zhao, Lei Yan, Quancheng Liu, Zichang He

“…This framework predicts and optimizes each robot’s kinematic model, thereby improving the system’s collaborative operations and dynamic decision-making capabilities. …”
Get full text

Distributed Beamforming for Relay Assisted Multiuser Machine-to-Machine Networks by Chen Chen, Lin Bai, Meiping Feng, Minhua Huang, Tian Tian

“…Numerical simulations for the proposed algorithms are presented showing the performance of the proposed schemes is close to that of the optimal scheme with global CSI in terms of bit error rate (BER) criterion.…”
Get full text

Deep learning-based prediction of individualized Real-time FSH doses in GnRH agonist long protocols by Na Kong, Yu Xia, Zhilong Wang, Hui Zhang, Liyan Duan, Yingchun Zhu, Chenyang Huang, Guijun Yan, Jie Mei, Wujun Li, Haixiang Sun

“…Most existing models are limited to static predictions of initial doses and do not support real-time adjustments throughout stimulation. …”
Get full text

Diabetes mellitus in the Russian Federation: dynamics of epidemiological indicators according to the Federal Register of Diabetes Mellitus for the period 2010–2022 by I. I. Dedov, M. V. Shestakova, O. K. Vikulova, A. V. Zheleznyakova, M. A. Isakov, D. V. Sazonova, N. G. Mokrysheva

“…The information-analytical system FDR is a key tool for systematizing the most important epidemiological and clinical characteristics of DM based on data from real clinical practice, which allows optimizing the algorithm of patient management and improving the quality of care for diabetes.…”
Get full text

Beyond the current state of just-in-time adaptive interventions in mental health: a qualitative systematic review by Claire R. van Genugten, Claire R. van Genugten, Melissa S. Y. Thong, Melissa S. Y. Thong, Melissa S. Y. Thong, Wouter van Ballegooijen, Wouter van Ballegooijen, Wouter van Ballegooijen, Annet M. Kleiboer, Annet M. Kleiboer, Donna Spruijt-Metz, Arnout C. Smit, Mirjam A. G. Sprangers, Mirjam A. G. Sprangers, Yannik Terhorst, Yannik Terhorst, Heleen Riper, Heleen Riper, Heleen Riper

“…Regarding the current state of studies, initial findings on usability, feasibility, and effectiveness appear positive.ConclusionsJITAIs for mental health are still in their early stages of development, with opportunities for improvement in both development and testing. For future development, it is recommended that developers utilize complex analytical techniques that can handle real-or near-time data such as machine learning, passive monitoring, and conduct further research into empirical-based decision rules and points for optimization in terms of enhanced effectiveness and user-engagement.…”
Get full text

Exploration of heterogeneity of treatment effects across exercise-based interventions for knee osteoarthritis by Paul A. Dennis, Livia Anderson, Cynthia J. Coffman, Sara Webb, Kelli D. Allen

“…Objective: Variability exists in the degree of improvement patients experience following exercise-based interventions (EBIs) for knee osteoarthritis (KOA), but understanding of this heterogeneity is limited. …”
Get full text

Modified Сomplex Treatment of the Cirhotic Patients with the Hepatopulmonary Syndrome of the Different Severity Degrees: Pathogenetic Reasoning and Efficiency by Abrahamovych M., Abrahamovych O., Tolopko S., Ferko M.

“…The modified by us method of the treatment of the patients considering the investigated pathogenic mechanisms of the liver cirrhosis and the HPS, its severity, as well as the conventional one, gave the positive result, but by its quality parameters the conventional medical complex significantly yielded comparing to the modified by us algorithm. Statistical analysis of the questionnaires MOS SF­36 before and after the treatment indicated a significant (p < 0.05) improvement of the physical activity, vitality, mental and general health, reducing of the pain and the role of the emotional stress in disability, resulting into the improvement of the physical and mental status of the patients treated by the modified by us technique and shows its effectiveness. …”
Get full text

Examining the Impact of Topography and Vegetation on Existing Forest Canopy Height Products from ICESat-2 ATLAS/GEDI Data by Yisa Li, Dengsheng Lu, Yagang Lu, Guiying Li

“…Spaceborne LiDAR FCH retrievals are more accurate in hilly regions, with a root mean square error (RMSE) of 4.99 m for ATLAS and 3.85 m for GEDI. …”
Get full text

Linking Animal Feed Formulation to Milk Quantity, Quality, and Animal Health Through Data-Driven Decision-Making by Oreofeoluwa A. Akintan, Kifle G. Gebremedhin, Daniel Dooyum Uyeh

“…However, despite its potential, the widespread adoption of data-driven feed formulation faces challenges such as data quality, technological limitations, and industry resistance, mostly disjointed processes. The objectives of this review are: (i) to explore the current advancements and challenges of data-driven decision-making in feed formulation, focusing on its connection to milk quantity and quality, and (ii) to highlight how this optimized feed formulation strategy improves sustainable dairy production.…”
Get full text

Machine learning-based prediction of carotid intima–media thickness progression: a three-year prospective cohort study by An Zhou, Kui Chen, Kui Chen, Yonghui Wei, Qu Ye, Qu Ye, Yuanming Xiao, Rong Shi, Jiangang Wang, Wei-Dong Li

“…Baseline CIMT, absolute monocyte count, sex, age, and LDL-C were identified as the most influential predictors. After Platt scaling, the calibration improved significantly across all the models. …”
Get full text

‘Machine Learning’ multiclassification for stage diagnosis of Alzheimer’s disease utilizing augmented blood gene expression and feature fusion by Manash Sarma, Subarna Chatterjee

“…Additionally, the ROC AUC scores were improved to 0.90, 0.85, and 0.89. Conclusion Using machine learning multiclassification techniques on blood gene expression profile data from ADNI and NCBI, we achieved the most promising results to date for diagnosing multiple stages of Alzheimer’s disease. …”
Get full text

Research Progress on Selective Depolymerization of Waste Plastics to High-Quality Liquid Fuels by Xinze LI, Zhicheng LUO, Rui XIAO

“…Photocatalysis prioritizes gaseous products (e.g., H2, CH4) with liquid fuel selectivity below 15% for most polymers. To address these challenges, three actionable pathways are proposed: (1) Pilot-scale optimization: Current studies predominantly use lab-scale feeds (<100 g), necessitating trials with industrial-grade plastics containing pigments and plasticizers. …”
Get full text

Functional Monitoring of Patients With Knee Osteoarthritis Based on Multidimensional Wearable Plantar Pressure Features: Cross-Sectional Study by Junan Xie, Shilin Li, Zhen Song, Lin Shu, Qing Zeng, Guozhi Huang, Yihuan Lin

“…The multidimensional gait features extracted from the data and physical characteristics were used to establish the KOA functional feature database for the plantar pressure measurement system. 40mFPWT and TUGT regression prediction models were trained using a series of mature machine learning algorithms. Furthermore, model stacking and average ensemble learning methods were adopted to further improve the generalization performance of the model. …”
Get full text

Pharmacological potential of 6,11-dihydro[1,2,4]triazolo[4’,3’:1,6]-pyrido[3,4-b]-5-carboxylic acid and its esters by S. O. Fedotov, A. S. Hotsulia

“…The combination of the indole fragment, which demonstrates activity due to its aromatic structure, with the 1,2,4-triazole nucleus, which is characterised by chemical stability and the ability to form hydrogen bonds, creates a promising basis for the development of new therapeutic agents with improved properties. The active implementation of various modifications of indole and 1,2,4-triazole frameworks is aimed at optimizing the pharmacokinetic and pharmacodynamic characteristics of medicinal products. …”
Get full text

Energy-Saving Techniques in the Next Generation of Mobile Communication Networks by Viroslava Kapustynska

“…In modern research, dynamic network scaling algorithms are more often presented, and location management investigation has been identified as a solution that can help improve energy-saving techniques and keep the quality of service at the optimal level.…”
Get full text