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    Acute stress-induced alterations in short-chain fatty acids: Implications for the intestinal and blood brain barriers by Cristina Rosell-Cardona, Sarah-Jane Leigh, Emily Knox, Emanuela Tirelli, Joshua M. Lyte, Michael S. Goodson, Nancy Kelley-Loughnane, Maria R. Aburto, John F. Cryan, Gerard Clarke

    Published 2025-07-01
    “…Microbially-produced metabolites such as short-chain fatty acids (SCFA) are key effectors within the gut-brain axis which can affect gut and brain function. The aim of this work is to determine if acute stress regulates SCFA production in the gut and to understand the associated implications for gastrointestinal and brain barrier function. …”
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    Secure Base Leadership in military training: enhancing organizational identification and resilience through work engagement by María C. Navas-Jiménez, Ana Laguía, Patricia Recio, Patricia Recio, Carlos García-Guiu, Alberto Pastor, Sergio Edú-Valsania, Fernando Molero, Fernando Molero, Mario Mikulincer, Juan A. Moriano

    Published 2024-12-01
    “…Data were analyzed using partial least squares structural equation modeling (PLS-SEM) to test the hypothesized relationships and mediation effects.ResultsThe findings revealed that secure base leadership is positively associated with work engagement among cadets. Work engagement significantly mediated the relationships between secure base leadership and both organizational identification and resilience. …”
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    Molecular turn in Yersinia pestis pathogenesis: implications of the gppA frameshift for bacterial survival in human macrophage by Hongyan Chen, Shiyang Cao, Yazhou Zhou, Tong Wang, Yang Jiao, Yafang Tan, Yarong Wu, Yifan Ren, Yajun Song, Jing-Ren Zhang, Zongmin Du, Ruifu Yang

    Published 2025-12-01
    “…This enhanced survival ability within macrophages could be a key factor for the virulence of Y. pestis towards humans. Our work sheds light on the molecular mechanisms behind Y. pestis host-specific pathogenicity, offering significant implications for enhancing our ability to predict and counteract the emergence of new infectious diseases.…”
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    In-silico analysis of nsSNPs in BCL-2 family proteins: Implications for colorectal cancer pathogenesis and therapeutics by Amanda Shen-Yee Kong, Yong Chiang Tan, Hin-Yee Thew, Kok-Song Lai, Swee-Hua Erin Lim, Sathiya Maran, Hwei-San Loh

    Published 2025-06-01
    “…The BCL-2 family proteins are implicated in CRC pathogenesis, yet the impacts of genetic variations within these proteins remains elusive. …”
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