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    Statin effects on the lipidome: Predicting statin usage and implications for cardiovascular risk prediction by Changyu Yi, Kevin Huynh, Yvette Schooneveldt, Gavriel Olshansky, Amy Liang, Tingting Wang, Habtamu B. Beyene, Aleksandar Dakic, Jingqin Wu, Michelle Cinel, Natalie A. Mellett, Gerald F. Watts, Joseph Hung, Jennie Hui, John Beilby, Joanne E. Curran, John Blangero, Eric K. Moses, John Simes, Andrew M. Tonkin, Leonard Kritharides, David Sullivan, Jonathan E. Shaw, Dianna J. Magliano, Agus Salim, Corey Giles, Peter J. Meikle, A. Tonkin, P. Aylward, D. Colquhoun, P. Glasziou, P. Harris, D. Hunt, A. Keech, S. MacMahon, P. Magnus, D. Newel, P. Nestel, N. Sharpe, J. Shaw, R.J. Simes, P. Thompson, A. Thomson, M. West, H. White, A. Thomson, S. Simes, D. Colquhoun, W. Hague, S. MacMahon, R.J. Simes, R.J. Simes, P. Glasziou, S. Caleo, J. Hall, A. Martin, S. Mulray, P. Barter, L. Beilin, R. Collins, J. McNeil, P. Meier, H. Willimott, P. Harris, W. Hague, D. Smithers, A. Tonkin, P. Wallace, H. Willimott, D. Hunt, J. Baker, P. Aylward, P. Harris, M. Hobbs, P. Thompson, N. Sharpe, D. Hunt, M. West, P. Thompson, H. White, P. Aylward, D. Colquhoun, D. Sullivan, A. Keech, P. Thompson, S. MacMahon, A. Tonkin, M. West, H. White, N. Anderson, G. Hankey, R.J. Simes, S. Simes, J. Watson, R.J. Simes, N. Sharpe, A. Thomson, A. Tonkin, H. White, W. Hague, J. Baker, M. Arulchelvam, S. Chup, J. Daly, J. Hanna, A. Leach, M. Lee, J. Loughhead, H. Lundie-Jenkin, J. Morrison, A. Martin, S. Mulray, S. Netting, A. Nguyen, H. Pater, R. Philip, G. Pinna, D. Rattos, S. Ryerson, V. Sazhin, S. Simes, R. Walsh, A. Keech, R.J. Simes, A. Clague, M. Mackie, J. Yallop, K. Boss, S. MacMahon, M. Whiting, M. Shepard, J. Leach, M. Gandy, J. Joughin, J. Seabrook, R. Abraham, J. Allen, F. Bates, I. Beinart, E. Breed, D. Brown, N. Bunyan, D. Calvert, T. Campbell, D. Condon-Paoloni, B. Conway, L. Coupland, J. Crowe, N. Cunio, B. Cuthbert, N. Cuthbert, S. D’Arcy, P. Davidson, B. Dwyer, J. England, C. Friend, G. Fulcher, S. Grant, K. Hellestrand, M. Kava, L. Kritharides, D. McGill, H. McKee, A. McLean, M. Neaverson, G. Nelson, M. O’Neill, C. Onuma, F. O’Reilly, A. Owensby, D. Owensby, J. Padley, G. Parnell, S. Paterson, C. Pawsey, R. Portley, K. Quinn, D. Ramsay, M. Russell, J. Ryan, B. Sambrook, L. Shields, J. Silberberg, S. Sinclair, D. Sullivan, P. Taverner, D. Taylor, M. Taylor, M. Threlfall, J. Turner, A. Viles, J. Waites, R. Walker, W. Walsh, K. Wee, P. West, R. Wikramanayake, D. Wilcken, J. Woods, R.K. Barnett, Z. Bogetic, H. Briggs, A. Broughton, L. Brown, A. Buncle, P. Calafiore, L. Carrick, Y. Cavenett, L. Champness, R. Clark, H. Connor, J. Counsell, J. Deague, G. Derwent-Smith, A. Driscoll, B. Feldtmann, L. Fisher, B. Forge, A. Hamer, H. Harrap, S. Hodgens, M. Hooten, J. Hurley, B. Jackson, J. Johns, J. Krafchek, H. Larwill, I. Lyall, S. Marks, M. Martin, B. Mason, J. McCabe, C. Medley, L. Morgan, L. Mullan, D. Ogilvy, G. Phelps, P. Phillips, H. Prendergast, D. Rose, G. Rudge, W. Ryan, M. Sallaberger, G. Savige, B. Sia, A. Soward, C. Steinfort, K. Tankard, J. Tippett, B. Tyack, J. Voukelatis, M. Wahlqvist, N. Walker, S. Whitten, R. Yee, M. Zanoni, R. Ziffer, K. Anderson, G. Aroney, C. Atkinson, K. Boyd, R. Bradfield, G. Cameron, D. Careless, A. Carle, P. Carroll, T. Carruthers, D. Chaseling, B. Cooke, S. Coverdale, B. Currie, M. d’Emden, F. Ekin, R. Elder, T. Elsley, L. Ferry, C. Gnanaharan, K. Graham, K. Gunawardane, C. Hadfield, C. Halliday, R. Halliday, A. Heyworth, B. Hicks, P. Hicks, T. Htut, L. Hughes, J. Humphries, H. LeGood, J. Nye, D. O’Brien, G. Real, K. Roberts, L. RossLee, J. Sampson, I. Scott, H. Smith, V. Smith-Orr, Y. Tan, B. Wicks, J. Wicks, S. Woodhouse, J. Bradley, L. Callaway, A. Calvert, J. Crettenden, A. Dufek, B. Dunn, C. Dunphy, D. Gow, I. Hamilton-Craig, K. Herewane, S. Keynes, L. McLeay, R. McLeay, L. Ng, C. Thomas, P. Tideman, L. Wilson, R. Yeend, C. Zhang, Y. Zhang, P. Bradshaw, M. Brooks, R. Burton, J. Garrett, K. Gotch-Martin, J. Hargan, B. Hockings, G. Lane, S. Ross, R. Cutforth, D. D’Silva, W. Hitchener, V. Kimber, G. Kirkland, P. Neid, R. Parkes, B. Singh, C. Singh, M. Smith, S. Smith, M. Templer, N. Whitehouse, R. Allen-Narker, R. Anandaraja, S. Anandaraja, P. Barclay, S. Baskaranathan, P. Bridgman, J. Brown, J. Bruning, J. Calton, A. Clague, M. Clark, D. Clarke, T. Cook, R. Coxon, M. Denton, A. Doone, R. Easthope, J. Elliott, C. Ellis, P. FosterPratt, C. Frenneux, M. Frenneux, D. Friedlander, D. Fry, L. Gibson, M. Gluyas, A. Hall, K. Hall, A. Hamer, H. Hart, P. Healy, J. Hedley, P. Heuser, H. Ikram, D. Jardine, J. Kenyon, H. King, T. Kirk, T. Lawson, P. Leslie, G. Lewis, E. Low, R. Luke, S. Mann, D. McClean, D. McHaffie, L. Nairn, H. Patel, L. Pearce, K. Ramanathan, R. Rankin, J. Reddy, S. Reuben, R. Ronaldson, D. Roy, H. Roy, P. Scobie, D. Scott, J. Scott, K. Skjellerup, R. Stewart, D. Walters, T. Wilkins, A. Vitanachy, P. Wright, A. Zambanini

    Published 2025-05-01
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    Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. by Lesley Jones, Peter A Holmans, Marian L Hamshere, Denise Harold, Valentina Moskvina, Dobril Ivanov, Andrew Pocklington, Richard Abraham, Paul Hollingworth, Rebecca Sims, Amy Gerrish, Jaspreet Singh Pahwa, Nicola Jones, Alexandra Stretton, Angharad R Morgan, Simon Lovestone, John Powell, Petroula Proitsi, Michelle K Lupton, Carol Brayne, David C Rubinsztein, Michael Gill, Brian Lawlor, Aoibhinn Lynch, Kevin Morgan, Kristelle S Brown, Peter A Passmore, David Craig, Bernadette McGuinness, Stephen Todd, Clive Holmes, David Mann, A David Smith, Seth Love, Patrick G Kehoe, Simon Mead, Nick Fox, Martin Rossor, John Collinge, Wolfgang Maier, Frank Jessen, Britta Schürmann, Reinhard Heun, Heike Kölsch, Hendrik van den Bussche, Isabella Heuser, Oliver Peters, Johannes Kornhuber, Jens Wiltfang, Martin Dichgans, Lutz Frölich, Harald Hampel, Michael Hüll, Dan Rujescu, Alison M Goate, John S K Kauwe, Carlos Cruchaga, Petra Nowotny, John C Morris, Kevin Mayo, Gill Livingston, Nicholas J Bass, Hugh Gurling, Andrew McQuillin, Rhian Gwilliam, Panos Deloukas, Ammar Al-Chalabi, Christopher E Shaw, Andrew B Singleton, Rita Guerreiro, Thomas W Mühleisen, Markus M Nöthen, Susanne Moebus, Karl-Heinz Jöckel, Norman Klopp, H-Erich Wichmann, Eckhard Rüther, Minerva M Carrasquillo, V Shane Pankratz, Steven G Younkin, John Hardy, Michael C O'Donovan, Michael J Owen, Julie Williams

    Published 2010-11-01
    “…<h4>Principal findings</h4>We found a significant overrepresentation of association signals in pathways related to cholesterol metabolism and the immune response in both of the two largest genome-wide association studies for LOAD.<h4>Significance</h4>Processes related to cholesterol metabolism and the innate immune response have previously been implicated by pathological and epidemiological studies of Alzheimer's disease, but it has been unclear whether those findings reflected primary aetiological events or consequences of the disease process. …”
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