Autophagy: An Overview of Molecular Mechanisms and Its Therapeutic Implications for Health and Disease by Hourolein Arab, Mohammad Reza Mofid, Mahboube Rahmati, Elahe Gharehkhani, Armin Mokhtariye, Mohammad Shokrzadeh

“…Dysfunctional autophagy has been implicated in the development of various diseases, including cancer, neurodegenerative disorders, metabolic diseases, and bacterial or viral infections. …”
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Exploring the genetic resources of yam in the Democratic Republic of Congo: implications for breeding by Idris Adejumobi, Idris Adejumobi, Adeyinka Saburi Adewumi, Fatim Ouattara, Esther Olatunde, Joseph Adheka, Didy Onautshu, Siraj Ismail Kayondo, Oluwafemi Alaba, Hapson Mushoriwa, Paterne Angelot Agre

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Multimodality Imaging in Aldosterone-Induced Cardiomyopathy: Early Detection and Prognostic Implications by Francesca Zoccatelli, Gabriele Costa, Matteo Merlo, Francesca Pizzolo, Simonetta Friso, Luigi Marzano

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Capsaicin as a Microbiome Modulator: Metabolic Interactions and Implications for Host Health by Iván Artemio Corral-Guerrero, Angela Elena Martínez-Medina, Litzy Yazmin Alvarado-Mata, Ana Cristina Figueroa Chávez, Roberto Muñoz-García, Miriam Paulina Luévanos-Escareño, Jazel Doménica Sosa-Martínez, María José Castro-Alonso, Padma Nimmakayala, Umesh K. Reddy, Nagamani Balagurusamy

“…This review aims to provide an integrative synthesis of capsaicin’s metabolism, its interaction with the gut microbiome, and its physiological implications across organ systems. <b>Methods:</b> We conducted a critical literature review of recent in vivo and in vitro studies exploring capsaicin’s metabolic fate, biotransformation by host enzymes and gut microbes, tissue distribution, and molecular pathways. …”
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Editorial commitment to trust and integrity in science: implications for pain and anesthesiology research by Tonya M. Palermo, Tonya M. Palermo, Didier Bouhassira, Karen D. Davis, Karen D. Davis, Hugh C. Hemmings, Robert W. Hurley, Joel Katz, Jaideep J. Pandit, Jaideep J. Pandit, Theodore J. Price, Michael E. Schatman, Michael E. Schatman, Stephan K. W. Schwarz, Stephan K. W. Schwarz, Dennis C. Turk, Marc Van de Velde, Marc Van de Velde, Matthew D. Wiles, Matthew D. Wiles, Tony L. Yaksh, David Yarnitsky

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Regulation of disease signaling by YOD1: potential implications for therapeutic strategies by Jiawei Zhao, Xiaotong Guo, Houzhong Li, Yujing Chen, Jingjing Du, Juzheng Zhang, Jinfeng Gan, Peitao Wu, Siqi Chen, Xinwen Zhang, Jinfeng Yang, Jiamin Jin

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Editorial Commitment to Trust and Integrity in Science: Implications for Pain and Anesthesiology Research by Palermo TM, Bouhassira D, Davis KD, Hemmings Jnr HC, Hurley RW, Katz J, Pandit J, Price T, Schatman ME, Schwarz SKW, Turk D, Van de Velde M, Wiles M, Yaksh T, Yarnitsky D

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Li diffusion in plagioclase crystals and glasses – implications for timescales of geological processes by F. Pohl, H. Behrens, M. Oeser, F. Marxer, R. Dohmen

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The XEC Variant: Genomic Evolution, Immune Evasion, and Public Health Implications by Alaa A. A. Aljabali, Kenneth Lundstrom, Altijana Hromić-Jahjefendić, Nawal Abd El-Baky, Debaleena Nawn, Sk. Sarif Hassan, Alberto Rubio-Casillas, Elrashdy M. Redwan, Vladimir N. Uversky

“…Narrative review synthesizes the most current literature on the SARS-CoV-2 XEC variant, focusing on its genomic evolution, immune evasion characteristics, epidemiological dynamics, and public health implications. To achieve this, we conducted a structured search of the literature of peer-reviewed articles, preprints, and official surveillance data from 2023 to early 2025, prioritizing virological, clinical, and immunological reports related to XEC and its parent lineages. …”
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Understanding the Dynamics of Filter Bubbles in Social Media Communication: A Literature Review by Tanase Tasente

“…Both supporting and critical viewpoints of these dynamics are evaluated, highlighting the nuanced role of filter bubbles in digital communication. Conclusions: The study underscores the broader societal implications of filter bubbles and calls for continued interdisciplinary research to develop effective solutions that foster informational diversity and a healthy democratic dialogue in the digital age. …”
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The challenges and opportunities for ethics in generative artificial intelligence in the digital age by Gabriel Silva-Atencio

“…Despite its growing popularity, the ethical implications of this technology remain under-explored. …”
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Framing diagnostic error: an epidemiological perspective by Montana Kekaimalu Hunter, Montana Kekaimalu Hunter, Montana Kekaimalu Hunter, Chithra Singareddy, Chithra Singareddy, Kenneth A. Mundt, Kenneth A. Mundt

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Decoding healthcare resilience for sustainable development goal 3: A machine learning analysis of global health systems by Ibrahim Alnafrah, Alexander Poroshin

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Artificial intelligence and predictive marketing: an ethical framework from managers’ perspective by Hina Naz, Muhammad Kashif

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Exploring artificial intelligence-based distribution planning and scheduling systems’ effectiveness in ensuring equitable vaccine distribution in low-and middle-income countries—wi... by Akuma Ifeanyichukwu, Vina Vaswani, Perihan Elif Ekmekci

“…It proposes an ethical framework consisting of 10 core components along with 11 implications and policy recommendations aimed at promoting the responsible and equitable use of AI support systems to enhance vaccine equity in future pandemics.…”
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Spatiotemporal dynamics of microcystin contamination in fish across the Lake Chaohu basin under the Yangtze River ten-year fishing ban: Ecological and human health implications by Shengpan Han, Wulai Xia, Jun He, Qianhui Wu, Wenli Xu, Jia Yu, Jun Chen, Ping Xie

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The implications of somatic symptom disorder on the impairment of daily life are greater in post-COVID syndrome than in asthma or COPD - results of a cross-sectional study in a rehabilitation clinic by Antonius Schneider, Alexander Hapfelmeier, Anna Greißel, Matthias Limbach, Gabriele Schwarzl, Franziska Ebert, Veronika Huber, Markus C. Hayden

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Implications of using the GLI-2012, GOLD and Australian COPD-X recommendations in assessing the severity of airflow limitation on spirometry among an Indigenous population with COPD: an Indigenous Australians perspective study by Timothy P Howarth, Elisha White, Helmi Ben Saad, Subash S Heraganahally

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Retrospective Study of Genetic Testing Results Reveals Pathogenic Variants Beyond BRCA1/2 in Hereditary Breast and Ovarian Cancer Cases in New Brunswick: Implications for Future Care by Kelly Gauvin, Véronique Allain, Nadia Bouhamdani, Chloe Williams, Yanis Saheb, Catherine Savoie, Lynn Macrae, Katherine Hodson, Yun Amber Zhu, Eric Allain, Mouna Ben Amor

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A Hybrid Model of In-Person and Telemedicine Diabetes Education and Care for Management of Patients with Uncontrolled Type 2 Diabetes Mellitus: Findings and Implications from a Multicenter Prospective Study by Ayla M. Tourkmani, Turki J. Alharbi, Abdulaziz M. Bin Rsheed, Azzam F. Alotaibi, Mohammed S. Aleissa, Sultan Alotaibi, Amal S. Almutairi, Jancy Thomson, Ahlam S. Alshahrani, Hadil S. Alroyli, Hend M. Almutairi, Mashael A. Aladwani, Eman R. Alsheheri, Hyfaa Salaheldin Sati, Budur Aljuaid, Abdulaziz S. Algarzai, Abood Alabood, Reuof A. Bushnag, Wala Ghabban, Muhammed Albaik, Salah Aldahan, Dalia Redda, Ahmed Almalki, Noura Almousa, Mohammed Aljehani, Alian A. Alrasheedy

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