The effect of androgen blockade on [68Ga]Ga-PSMA-11 and [18F]FDG PET uptake in patients with recurrent or metastatic salivary duct carcinoma: a prospective imaging study by Niels J. van Ruitenbeek, Maike J. M. Uijen, Chantal M. L. Driessen, Maartje C. van Rijk, Steffie M. B. Peters, Bastiaan M. Privé, Gerald W. Verhaegh, Adriana C. H. van Engen-van Grunsven, Martin Gotthardt, James Nagarajah, Carla M. L. van Herpen

“…A similar upregulation of PSMA in SDC would have implications for future studies with PSMA-targeted imaging and therapy. …”
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Nephrometry Scores Based on Three-dimensional Virtual Models Improve the Accuracy of Predicting Postoperative Complications After Robotic Partial Nephrectomy: Results from a Collab... by Daniele Amparore, Federico Piramide, Paolo Verri, Enrico Checcucci, Alberto Piana, Giuseppe Basile, Alessandro Larcher, Andrea Gallioli, Angelo Territo, Josep Maria Gaya, Pietro Piazza, Stefano Puliatti, Antonio Andrea Grosso, Andrea Mari, Riccardo Campi, Laura Zuluaga, Ucpinar Burak, Badani Ketan, Sergio Serni, Umberto Capitanio, Francesco Montorsi, Alexandre Mottrie, Cristian Fiori, Andrea Minervini, Peter Wiklund, Alberto Breda, Francesco Porpiglia

“…Conclusions and clinical implications: In this multi-institutional study, 3DVMs had superior accuracy to 2D images for evaluating the surgical complexity of renal masses and frequently led to downgrading. …”
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The genetic landscape of sporadic adult-onset degenerative ataxia: a multi-modal genetic study of 377 consecutive patients from the longitudinal multi-centre SPORTAX cohortResearch... by Danique Beijer, David Mengel, Demet Önder, Carlo Wilke, Andreas Traschütz, Jennifer Faber, Dagmar Timmann, Sylvia Boesch, Stefan Vielhaber, Thomas Klopstock, Bart P. van de Warrenburg, Gabriella Silvestri, Christoph Kamm, Iselin Marie Wedding, Zofia Fleszar, Florian Harmuth, Claudia Dufke, Bernard Brais, Olaf Rieß, Ludger Schöls, Tobias Haack, Stephan Züchner, David Pellerin, Thomas Klockgether, Matthis Synofzik, Friedrich Erdlenbruch, Andreas Thieme, Judith van Gaalen, Christos Ganos, Jun-Suk Kang, Marcus Grobe-Einsler, Ilaria Giordano

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Viral load levels measured at set-point have risen over the last decade of the HIV epidemic in the Netherlands. by Luuk Gras, Suzanne Jurriaans, Margreet Bakker, Ard van Sighem, Daniela Bezemer, Christophe Fraser, Joep Lange, Jan M Prins, Ben Berkhout, Frank de Wolf, ATHENA National Observational Cohort Study

“…The ATHENA national observational cohort contributed all patients who seroconverted in or after 1996; the Amsterdam Cohort Studies (ACS) contributed seroconverters before 1996. …”
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Combination of Cpb-Hsp70 typing methods reveals genetic divergence between Leishmania infantum strains causing human tegumentary leishmaniasis in northern Italy and central Spain:... by Tommaso Gritti, Carmen Chicharro, Eugenia Carrillo, Jose Carlos Solana, Javier Moreno, Elena Carra, Margherita Ortalli, Sara Morselli, Valeria Gaspari, Margherita Zanazzi, Tiziana Lazzarotto, Gianluca Rugna, Stefania Varani

“…Currently, no standardized molecular surveillance of circulating Leishmania strains is performed in European endemic areas, despite the potential public health implications of parasite biodiversity. This study aims to characterize parasite population haplogroups causing TL in two active endemic areas in southern Europe, i.e. …”
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Exploring skin aging-associated genotypes; Moving toward delivery of precision medicine-based care more than beyond skin deep care: a genome-wide association study by Sam Nowroozi, Khalil Khashei Varnamkhasti, Samire Khashei Varnamkhasti, Leila Naeimi, Behrouz Naeimi, Sirous Naeimi

“…All statistical analyses were performed using SPSS software, and differences were taken as significant at P < 0.05. Results This study results implicate that skin aging obtains on a genetic level and in particular the results suggest that His139Arg, Tyr113His and P187S represent true genetic susceptible loci for cutaneous aging related traits. …”
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Increased nuclear expression of DNA damage inducible transcript 4 can serve as a potential prognostic biomarker in patients with gliomas: a study based on data mining and experimen... by Alireza Sadeghipour, Fahimeh Fattahi, Zahra Madjd, Fatemeh Tajik, Farnoosh Sedaghati, Leili Saeednejad Zanjani

“…Abstract Introduction DNA damage-inducible transcript 4 (DDIT4), induced under cellular stress conditions, has been implicated in malignancies due to its abnormal expression patterns. …”
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Association of FV G1691A, FV H1299R, and FII G20210A variations with thrombosis and coronary artery disease (CAD): A population-based study by Ünallı Özmen Sevda, Özarda Yeşim, Köseler Aylin, Sabırlı Ramazan, Kaynak Derya Sucu, Koç Ibrahim

“…Methods: A case-control study included 406 healthy individuals and 64 CAD patients. …”
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Industry&#x2014;Challenge to Pro-Environmental Manufacturing of Goods Replacing Single-Use Plastic by Indian Industry: A Study Toward Failing Ban on Single-Use Plastic Access by Shabbiruddin, Neeraj Kanwar, Vinay Kumar Jadoun, Jayalakshmi N. S., Asyraf Afthanorhan, Nuzhat Fatema, Hasmat Malik, Mohammad Asef Hossaini

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Are the knowledge of non-malignant asbestos-related diseases and lung function impairment differentially associated with psychological well-being? A cross-sectional study in former... by Jessica Lang, Michael K Felten, Thomas Kraus

“…Therefore, the aim of the present study was to test for our cohort whether non-malignant ARD and lung function impairment have differential effects on mental health and psychological strain.Design Cross-sectional study.Participants and setting Overall, 612 male participants (mean age=66.2 years, SD=9.5) attending a surveillance programme for ARDs received routine examinations including lung function testing (24% refused to fill in the psychological questionnaire) at a German university hospital study centre from August 2008 to August 2013.Outcome measures Using multiple hierarchical regression analysis, ARD diagnosis and lung function impairment were used to predict psychological health as measured with validated questionnaires for depression and anxiety. …”
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The association of perirenal adipose tissue accumulation with left ventricular hypertrophy and the mediating role of insulin resistance: a cross-sectional study involving 1112 indi... by Wei Wang, Yang Chen, Xiu Ping Qiu, Xiu Li Guo

“…ObjectiveRecent studies have underscored the metabolic and cardiovascular regulatory capacity of perirenal adipose tissue (PAT), implicating its potential involvement in the pathogenesis of left ventricular hypertrophy (LVH). …”
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Estratégia de marcas próprias no varejo supermercadista: um estudo comparativo entre Brasil e Inglaterra Private label strategy on food retailers: a comparative study between Brazi... by Verônica Angélica Freitas de Paula, Andrea Lago da Silva, Éderson Luiz Piato

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Estratégia de marcas próprias no varejo supermercadista: um estudo comparativo entre Brasil e Inglaterra Private label strategy on food retailers: a comparative study between Brazi... by Verônica Angélica Freitas de Paula, Andrea Lago da Silva, Éderson Luiz Piato

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Branched chain amino acid transaminase 1 (BCAT1) is overexpressed and hypomethylated in patients with non-alcoholic fatty liver disease who experience adverse clinical events: A pi... by Kara Wegermann, Ricardo Henao, Anna Mae Diehl, Susan K Murphy, Manal F Abdelmalek, Cynthia A Moylan

“…Given the potential for BCAT1 to identify patients at risk for poor outcomes, and the potential therapeutic implications, these results should be validated in larger prospective studies.…”
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Geology, Archaeology, and Historical Studies of the Late 16th Century Plinian Eruption of Raung Volcano: A Potential Case for Disaster Geotourism in Ijen UNESCO Global Geopark, Eas... by Firman Sauqi Nur Sabila, Mirzam Abdurrachman, Asep Saepuloh, Idham Andri Kurniawan, Abdillah Baraas, Dwi Fitri Yudiantoro, Hery Kusdaryanto

“…These diverse sources estimate that the eruption resulted in approximately 10,000 casualties, marking it as one of the most significant volcanic disasters in the past 500 years. The implications of this eruption extend beyond historical documentation, providing a critical case study for advancing disaster mitigation strategies through geotourism in the geopark area. …”
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Contribution of type 2 diabetes to all-cause mortality, cardiovascular disease incidence and cancer incidence in white Europeans and South Asians: findings from the UK Biobank popu... by Karien Stronks, Anne Sillars, Stamatina Iliodromiti, Stuart Robert Gray, Mirthe Muilwijk, Heather Waddell, Rosemary Brown, Lyn Ferguson, Jason Martin Regnald Gill

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Changes in global quality of life after treatment with immune checkpoint inhibitors in patients receiving different treatment regimens for advanced stage lung cancer in the Netherl... by Manuela Quaresma, Bernard Rachet, Geertruida H De Bock, Clémence Leyrat, Willemijn J Maas, Erick Suazo-Zepeda, Ananya Malhotra, Petra C Vinke, Jeroen T J.N Hiltermann

“…Despite improved survival benefits, ICIs may cause side effects impacting patients’ quality of life (QoL). We aim to study the changes in global QoL (gQoL) of patients with advanced-stage lung cancer up to 18 months after treatment with ICIs between 2015 and 2021.Methods and analysis A longitudinal cohort study was conducted using the Oncological Life Study: Living well as a cancer survivor data-biobank from the University Medical Center Groningen. …”
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Exploration of the optimal regimen of gastric mucosal cleansing medication for the H. pylori population before ME-NBI screening: study protocol for a single-center, single-blind, r... by Xinyi Mu, Yi Fan, Jingyu Xu, Rui Xie

“…This randomized controlled trial study protocol aims to investigate the effect of different combinations of medications on the quality of gastric mucosal cleansing in an H. pylori-infected population.MethodsThis study is a prospective, randomized, single-blind, single-center trial. …”
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Patients from low-middlProfile and management of patients from low-middle socioeconomic status with thoracic traumae socioeconomic status with thoracic trauma: A prospective observ... by Heleen van Aswegen, Ronel Roos, Elizma Haarhoff, Josslyn de Kock, Humairaa Ebrahim, Sameer Tootla, Muhammad Vally, Monika Fagevik Olsén

“…Adults with thoracic trauma diagnosis were consecutively screened for inclusion. Study objectives guided information retrieved from records. …”
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Changing age profile and incidence of injecting drug use initiation among people in Australia who inject drugs: evidence from two national repeated cross-sectional studiesResearch... by Olivia Price, Lisa Maher, Amy Peacock, Farzaneh Zolala, Louisa Degenhardt, Paul Dietze, Sarah Larney, Seraina Agramunt, Samantha Colledge-Frisby, Bradley Mathers, Dan Lewer, Rachel Sutherland

“…In both surveys, the median age increased over the study period (IDRS: 28–43 years; ANSPS 28–44 years). …”
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