Exploring the effect of the triglyceride-glucose index on bone metabolism in prepubertal children, a retrospective study: insights from traditional methods and machine-learning-bas... by Shunshun Cao, Aolei Chen, Botian Song, Yangyang Hu

“…Conclusions The TyG index is a reliable predictor of bone metabolic disorders in prepubertal obese children, and the interpretable CatBoost model provides a cost-effective tool for early intervention. This study has important implications for prevention strategies for disorders of bone metabolism in prepubertal obese children to reduce the risk of skeletal fragility in adulthood or old age.…”
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Association between Chinese visceral adiposity index and risk of new-onset hypertension in middle-aged and older adults with prediabetes: evidence from a large national cohort stud... by Lanlan Li, Lanlan Li, Linqiang Xi, Linqiang Xi, Qianhui Wang

“…However, the predictive value of CVAI for the incidence of hypertension in adults with prediabetes is unclear. This study aimed to assess the predictive utility of the CVAI for the new onset of hypertension in middle-aged and older adult Chinese individuals with prediabetes.MethodsA prospective cohort study was conducted involving participants aged 45 years and above with prediabetes from the 2011–2012 cohort of the China Health and Retirement Longitudinal Study (CHARLS). …”
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Factor analysis, emotional experience and behavioral feedback of contemporary Chinese youth participating in short-term monasticism: a qualitative study based on the online questio... by Chao Liu, Chao Liu, Li-Jen Lin, Li-Jen Lin, Hao Chen, Hao Chen, Thu-Hua Liu, Thu-Hua Liu, Huang-Li Lin, Wen-Ko Chiou, Wen-Ko Chiou, Wen-Ko Chiou, Wen-Ko Chiou

“…IntroductionThis study explores the psychological motivations, emotional experiences, and behavioral feedback of contemporary Chinese youth participating in short-term monasticism. …”
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Case study of radiation absorptive and chemical reactive impacts on unsteady MHD natural convection flowing of Cu-Al2O3/H2O hybridized nanofluid by Rekha Satish, Buchanahalli Thimmaiah Raju, Mummadisetty Umamaheswar, Vijayakumar Varma Sibyala, Charankumar Ganteda, Assmaa Abd-Elmonem, Fayza Abdel Aziz ElSeabee, Neissrien Alhubieshi, Mohamed R. Eid, Wasim Jamshed, Hijaz Ahmad

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Study on external treatment of Traditional Chinese Medicine in the treatment of opioid-induced constipation (中医外治法在阿片类药物相关性便秘中的研究) by LI Guomin (李国敏), GONG Yang (龚杨), FU Yanli (付艳丽), ZHONG Yinqin (钟印芹), DENG Jinfeng (邓金凤), LIU Ying (刘莹), CHEN Jie (陈洁)

“…The effective prevention and treatment of OIC have vital clinical implications. This study summarized advances in the Traditional Chinese Medicine (TCM) etiology of cancer pain OIC and recent developments in external TCM treatment, and anticipations to assist as a reference for optimizing TCM interventions, as well as the cancerous pathogenesis provided by OIC, conduct a scientific investigation of pain. …”
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Case Report: Clinical impact of BRCA1 and BRIP1 vs. BRCA1 and BRCA2 germline double heterozygosity in ovarian cancer: a comparative case study by Limei Zheng, Qianyuan Zhu, Qianyuan Zhu, Fenglan Zhang, Hao Qiu, Lan Qin, Jianhua Yang, Ming Qi, Ming Qi, Ming Qi, Ming Qi

“…Germline double heterozygosity (GDH), particularly involving rare combinations, remains poorly understood. This study presents the first report of BRCA1/BRIP1 GDH in a case of Chinese OC patients and compares their clinical characteristics and treatment responses to a patient with BRCA1/BRCA2 GDH. …”
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Association of socioeconomic status on return to work following primary total hip arthroplasty: a Danish population-based cohort study on 9,431 patients from 2008–2018 by Peter Alsing, Julie B Pajaniaye, Martin G Stisen, Søren Overgaard, Erzsébet Horváth-Puhó, Inger Mechlenburg, Alma B Pedersen

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Socioeconomic Inequalities in Body Mass Index across Adulthood: Coordinated Analyses of Individual Participant Data from Three British Birth Cohort Studies Initiated in 1946, 1958... by David Bann, William Johnson, Leah Li, Diana Kuh, Rebecca Hardy

“…<h4>Methods and findings</h4>The sample comprised up to 22,810 participants with 77,115 BMI observations in the 1946 MRC National Survey of Health and Development (ages 20 to 60-64), the 1958 National Child Development Study (ages 23 to 50), and the 1970 British Cohort Study (ages 26 to 42). …”
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Trends in maternal body mass index, macrosomia and caesarean section in first-time mothers during the pandemic: a multicentre retrospective cohort study of 12 Melbourne public hosp... by Andrew J. Goldsack, Melvin B. Marzan, Daniel L. Rolnik, Anthea C. Lindquist, Joanne M. Said, Kirsten R. Palmer, Penelope M. Sheehan, Stephanie Potenza, Natasha Pritchard, Clare L. Whitehead, Jolyon Ford, Ben W. Mol, Susan P. Walker, Lisa Hui

“…Design Multi-centre retrospective cohort study and interrupted time-series analysis. Setting Metropolitan Melbourne, Victoria. …”
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Xylem Sap Mycobiota in Grapevine Naturally Infected with <i>Xylella fastidiosa</i>: A Case Study: Interaction of <i>Xylella fastidiosa</i> with <i>Sclerotinia sclerotiorum</i> by Analía Perelló, Antonia Romero-Munar, Sergio I. Martinez, Antonio Busquets, María Cañellas, Bárbara M. Quetglas, Rafael Bosch, Jaume Vadell, Catalina Cabot, Marga Gomila

“…<i>Fastidiosa</i> (<i>Xff</i>), the causal agent of Pierce’s disease. This study investigated: (1) the diversity of culturable fungal endophytes in the xylem sap of naturally <i>Xff</i>-infected grapevines, and (2) the interaction between <i>Xff</i> and the pathogenic fungus <i>Sclerotinia sclerotiorum</i> identified in the sap. …”
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Associations between attainment of incentivized primary care indicators and incident lower limb amputation among those with type 2 diabetes: a population-based historical cohort st... by Eszter P Vamos, Jonathan Valabhji, Laura H Gunn, Pasha Normahani, Usman Jaffer, Ailsa J McKay, German Molina

“…This has important implications for diabetes management and medical decision-making for patients, as well as type 2 diabetes quality improvement programs.…”
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Comparative analysis of 2 approaches to monitor countries' progress towards full and equal access to sexual and reproductive health care, information, and education in 75 countries... by Jewel Gausman, Richard Adanu, Delia A B Bandoh, Neena R Kapoor, Ernest Kenu, Ana Langer, Magdalene A Odikro, Thomas Pullum, R Rima Jolivet

“…Significant challenges related to the indicator's calculation have been noted, which have important implications for the indicator's validity in measuring progress towards meeting the SDG target. …”
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A Comparative Study of the Relationship Between Rights and Good in Rawlsian Perspective on the Protests Against the Murder of George Floyd (2020) and the Protests Against the Pales... by Maysam Baharloo, Mohamed Sadiq Nosratpanah

“…Extended AbstractIntroduction and Objectives: This article offers a comparative study of the relationship between the concepts of the “right” and the “good” in John Rawls’s political philosophy, with a focus on their implications for domestic politics in the United States. …”
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Co-producing a transition model of care for eating disorders: lessons learned from a multi-perspective qualitative study with young people, carers and mental health professionals by Maria Livanou, Anya Heneghan, Grace Hill, Alanta McKenzie, Marta Marlais, Francesca Marshall, Zara Smalley, Eleni Xanthopoulou, Nora Kornai, Jessica Wilks, Ailsa McKay, Jun Teh, Isabel Taylor, Charlotte Burton, Julian Baudinet

“…Conclusions These findings have significant clinical implications for transitional care, emphasising the need for a more standardised and supportive approach to the transition from CAMHS to AMHS. …”
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Aerosol particle number concentration, ultrafine particle number fraction, and new particle formation measurements near the international airports in Berlin, Germany – First result... by Simonas Kecorius, Susanne Sues, Leizel Madueño, Alfred Wiedensohler, Ulf Winkler, Andreas Held, Sabine Lüchtrath, David C. Beddows, Roy M. Harrison, Mario Lovric, Vanessa Soppa, Barbara Hoffmann, Miriam Wiese-Posselt, Andreas Kerschbaumer, Josef Cyrys

“…This can be explained by nucleation events, which notably affected PNC.The presented findings will play a pivotal role in forthcoming source attribution and epidemiological investigations, offering a holistic understanding of airports’ impact on airborne pollutant levels and their health implications. The study calls for further investigations of air-traffic-related physical–chemical pollutant properties in areas found further away (> 10 km) from airports.…”
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An Increased Frequency in HLA Class I Alleles and Haplotypes Suggests Genetic Susceptibility to Influenza A (H1N1) 2009 Pandemic: A Case-Control Study by Ramcés Falfán-Valencia, Arun Narayanankutty, Juan M. Reséndiz-Hernández, Gloria Pérez-Rubio, Alejandra Ramírez-Venegas, Karol J. Nava-Quiroz, Nora E. Bautista-Félix, Gilberto Vargas-Alarcón, Manuel D. J. Castillejos-López, Andrés Hernández

“…This work has significant implications for accessing population transmission risk for A H1N1/09 or a similar strain breakout in the future.…”
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Analysis of the Reduction in the Duration of Sick Leave for 32,512 Psoriasis Patients Following the Integration of Targeted Therapies for Psoriatic Disease into the Brazilian Healt... by D'Almeida LFV, Duarte GV, Godinho MP, Cariello LH, Sousa GJB, Gomes CM

“…The Brazilian Unified Health System offers an interesting case study for analysing the financial implications of cutting-edge healthcare technologies. …”
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Assessing the impact of COmorbidities and Sociodemographic factors on Multiorgan Injury following COVID-19: rationale and protocol design of COSMIC, a UK multicentre observational... by Christopher E Brightling, Kamlesh Khunti, Naveed Sattar, Colin Berry, John P Greenwood, Gerry P McCann, Kelly S Parke, Joanne V Wormleighton, Stefan Neubauer, Betty Raman, Charalambos Antoniades, Elizabeth M Tunnicliffe, Alastair Moss, Jayanth Ranjit Arnold, Mark Toshner, Sue Francis, Sandeep S Hothi, Stephen M Smith, Mohamed Elshibly, Simran Shergill, Rachel J England, George J Hudson, James Wild

“…The pathophysiology and long-term clinical implications of multi-organ injury remain to be fully elucidated. …”
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"The research assistants kept coming to follow me up; I counted myself as a lucky person": Social support arising from a longitudinal HIV cohort study in Uganda. by Jeffrey I Campbell, Angella Musiimenta, Sylvia Natukunda, Nir Eyal, Jessica E Haberer

“…The extent to which social support arises from study participation, its range and depth, and its implications for observational study conduct, have not been extensively described.…”
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Rapid tests to inform triage and antibiotic prescribing decisions for adults presenting with suspected acute respiratory infection: a rapid evidence synthesis of clinical effective... by Katie Scandrett, Jill Colquitt, Rachel Court, Fiona Whiter, Bethany Shinkins, Yemisi Takwoingi, Emma Loveman, Daniel Todkill, Paramjit Gill, Daniel Lasserson, Lena Al-Khudairy, Amy Grove, Yen-Fu Chen

“…Our review found that the test may represent good value for money, but the studies were limited as they only considered costs and health implications in the short term. …”
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