Increased adverse pregnancy outcomes among decreased assisted reproductions during the COVID-19 pandemic: insights from a birth cohort study in Southwest China by Jinnuo Hu, Jiaxin Liu, Qin Zeng, Jiuzhi Zeng, Min Luo, Dan He, Yan Zhang, Piao Zhang, Juan Ming, Weixin Liu

“…Conclusion ART services have been significantly impacted by the COVID-19 pandemic, and the resulting delays in ART services have had notable implications for maternal birth outcomes.…”
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The changes in global burden of autoimmune diseases two years after the COVID-19 pandemic: a trend analysis based on the Global Burden of Disease Study 2021 by Danting Zhang, Wanyu Hua, Fangfang Sun, Chao Wen, Lai Yee Cheong, Ruiyan Xie, Koon Ho Chan, Shirley C.W. Chan, Xue Li, Shuang Ye, Desmond Y.H. Yap

“…These observations have important implications for subsequent healthcare planning and resource allocation.…”
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Clonal hematopoiesis of indeterminate potential and type 2 diabetes mellitus among patients with STEMI: from a prospective cohort study combing bidirectional Mendelian randomizatio... by Xiaoxiao Zhao, Jiannan Li, Shaodi Yan, Yu Tan, Runzhen Chen, Nan Li, Jinying Zhou, Chen Liu, Peng Zhou, Yi Chen, Hongbing Yan, Hanjun Zhao, Li Song

“…Abstract Aim Both clonal hematopoiesis of indeterminate potential (CHIP) and type 2 diabetes mellitus (T2DM) are conditions closely associated with advancing age. This study delves into the possible implications and prognostic significance of CHIP and T2DM in patients diagnosed with ST-segment elevation myocardial infarction (STEMI). …”
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‘What’s the word? That’s the word!’: linguistic features of Filipino queer language by Mark Bedoya Ulla, Jonathan Marcos Macaraeg, Renz E. Ferrera

“…Understanding queer language, which includes knowing its meaning and its applications, is essential not only for understanding sexuality and fostering language inclusivity but also for acknowledging the multifaceted uses of language across all societal groups. This study explored the semantic nuances and underlying patterns of Filipino queer language using Word Sense Disambiguation (WSD). …”
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Unveiling the Molecular Mechanisms Behind the Devastating Impact of the ALK Protein on Pediatric Cancers: Insights into Deleterious SNPs through In Silico Predictions, Molecular Do... by Abdulhadi Almazroea

“…ALK, a receptor tyrosine kinase, plays a vital role in normal cellular processes, but genetic alterations and aberrant activation of the ALK gene have been implicated in various pediatric cancer types. While genetic alterations have been well studied, the precise molecular mechanisms underlying the pathogenicity of the ALK protein in pediatric cancers remain poorly understood.…”
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Impact of tobacco habits on poor oral health status among bone-factory workers in a low literacy city in India: A cross-sectional study. by Naved Alam, Warisha Mariam

“…Additionally, tailored intervention for tobacco cessation should be implicated to maintain the general and oral health of industrial workers.…”
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Do People Trust News on Media Overall as Much as They Trust the News They Actually Use? A Study on Credibility of “News I Use” and Credibility of News on Media Overall by Najin Jun

“…This study aims to understand how people evaluate the credibility of news they use every day and how such evaluation is related to their credibility assessment of news on media overall. …”
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Pelaksanaan Pengawasan Makanan yang Beredar pada Konsumen oleh BBPOM di Makassar (Studi Pelaksanaan UU No. 8 Tahun 1999 tentang Perlindungan Konsumen) by Amrizal, Istiqamah

“…This research discusses the "Implementation of Food Supervision on Consumer by BBPOM in Makassar". The purpose of this study is to understand the implementation of BBPOM supervision in Makassar regarding the circulation of expired food and the factors that hinder BBPOM in conducting supervision. …”
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A review shows that ATG10 has been identified as a potential prognostic marker and therapeutic target for cancer patients based on real-world studies by Ke Shi, Di Ke, Feng Li, Rong-Shu Shi, Tao Liu, Dan Li, Qun-Xian Zhang

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The MLH1 c.1852_1853delinsGC (p.K618A) variant in colorectal cancer: genetic association study in 18,723 individuals. by Anna Abulí, Luis Bujanda, Jenifer Muñoz, Stephan Buch, Clemens Schafmayer, Maria Valeria Maiorana, Silvia Veneroni, Tom van Wezel, Tao Liu, Helga Westers, Clara Esteban-Jurado, Teresa Ocaña, Josep M Piqué, Montserrat Andreu, Rodrigo Jover, Angel Carracedo, Rosa M Xicola, Xavier Llor, Antoni Castells, EPICOLON Consortium, Malcolm Dunlop, Robert Hofstra, Annika Lindblom, Juul Wijnen, Paolo Peterlongo, Jochen Hampe, Clara Ruiz-Ponte, Sergi Castellví-Bel

“…A significant proportion of variants identified by screening these genes correspond to missense or noncoding changes without a clear pathogenic consequence, and they are designated as "variants of uncertain significance", being the c.1852_1853delinsGC (p.K618A) variant in the MLH1 gene a clear example. The implication of this variant as a low-penetrance risk variant for CRC was assessed in the present study by performing a case-control study within a large cohort from the COGENT consortium-COST Action BM1206 including 18,723 individuals (8,055 colorectal cancer cases and 10,668 controls) and a case-only genotype-phenotype correlation with several clinical and pathological characteristics restricted to the Epicolon cohort. …”
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Wearable Neurotechnology for the Treatment of Insomnia: The Study Protocol of a Prospective, Placebo-Controlled, Double-Blind, Crossover Clinical Trial of a Transcranial Electrical... by Keenan Caswell, Grace Roe, Emamoke Odafe, Subodh Arora, Caddie Motoni, John Kent Werner

“…Military service members demonstrate an increased risk of insomnia, which doubles after deployment. This study will investigate the ability of a translational device, Teledyne PeakSleep™ (Teledyne Scientific & Imaging, Durham, NC, USA), to reduce sleep onset latency and the time spent awake after sleep onset, with improvement in the subjective benefits of sleep for patients with insomnia by enhancing the brain rhythms within the frontal lobe implicated in slow wave generation. …”
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Investigating the Osteoregenerative Properties of <i>Juglans regia</i> L. Extract on Mesenchymal Stem Cells and Osteoblasts Through Evaluation of Bone Markers: A Pilot Study by Alina Hanga-Fărcaș, Gabriela Adriana Filip, Simona Valeria Clichici, Laura Grațiela Vicaș, Olga Şoritău, Otilia Andercou, Luminița Fritea, Mariana Eugenia Mureșan

“…The osteoregenerative properties of the leaf extract were evaluated in terms of cell viability, bone mineralization (by staining with alizarin red) and the expression of osteogenesis markers such as osteocalcin (OC), osteopontin (OPN), dentin matrix acidic phosphoprotein 1 (DMP1) and collagen type 1A. Another compound implicated in oxidative stress response, but also a bone homeostasis regulator, nuclear factor erythroid 2-related factor 2 (NRF2), was studied by immunocytochemistry. …”
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Elevated CD14 in B cells associates with reduced ovarian cancer risk via CD80 + dendritic cell interaction: a multi-omics study by Mengyu Zheng

“…Methods This study employed single-cell RNA sequencing (scRNA-seq) to analyze peripheral blood mononuclear cells (PBMCs) from ovarian cancer patients and healthy donors. …”
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Spatial Analysis of the Neuronal Density of Aminergic Brainstem Nuclei in Primary Neurodegenerative and Vascular Dementia: A Comparative Immunocytochemical and Quantitative Study U... by Yan Yang, Konrad Beyreuther, Horst P. Schmitt

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Effect of two different types of exercise volumes on exercise capacity, physical activity, and quality of life in subjects undergoing percutaneous coronary intervention: a pilot st... by Adriana Angarita-Fonseca, Adriana Marcela Jacome-Hortúa, Andrea Juliana Ortiz-Patiño, Zully Rocío Rincón-Rueda, Carmen Juliana Villamizar-Jaimes, Erika Tatiana Paredes-Prada, Juan Carlos Sánchez-Delgado

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A genome-wide association study of high-sensitivity C-reactive protein in a large Korean population highlights its genetic relationship with cholesterol metabolism by Kwangyeon Oh, Minju Yuk, Soyoun Yang, Jiyeong Youn, Qian Dong, Zhaoming Wang, Nan Song

“…This study was performed on data from 71,019 Koreans and is one of the largest East Asian studies. …”
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Quantification of Multi-Organ 11β-Hydroxysteroid Dehydrogenase Type 1 Enzyme Levels in a Zucker Fatty Rat Model: A PET Imaging Study by Jason Bini PhD, Jordan Strober PhD, Michael Kapinos BS, Ming-Qiang Zheng PhD, Songye Li PhD, Jim Ropchan PhD, Nabeel Nabulsi PhD, Yiyun Huang PhD, Rachel J. Perry PhD, Daniel F. Vatner MD, PhD, Richard E. Carson PhD

“…Dysregulation of intracellular glucocorticoid action is implicated in metabolic diseases. Assessing 11β-HSD1 enzyme levels in vivo may be key to understanding obesity pathophysiology. …”
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The elevated levels of soluble growth stimulation expressed gene 2 are associated with coronary atherosclerotic plaque destabilization in unstable angina patients: a case control s... by Ning Li, Xinjian Li, Lin Ni, Xuewen Li

“…Methods This study enrolled 122 patients admitted with UA and 107 age- and sex-matched healthy controls. …”
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Identification of Transcriptomic Differences in Induced Pluripotent Stem Cells and Neural Progenitors from Amyotrophic Lateral Sclerosis Patients Carrying Different Mutations: A Pi... by Chiara Sgromo, Martina Tosi, Cristina Olgasi, Fabiola De Marchi, Francesco Favero, Giorgia Venturin, Beatrice Piola, Alessia Cucci, Lucia Corrado, Letizia Mazzini, Sandra D’Alfonso, Antonia Follenzi

“…Overall, we generated iPSC lines from ALS patients with diverse genetic backgrounds offering a tool for unravelling the intricate molecular landscape of ALS, paving the way for identifying key pathways implicated in pathogenesis and the disease’s phenotypic variability.…”
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Can we empirically derive a geographic definition of ‘coastal’ for use in cancer data reporting? An ecological modelling study using England’s national cancer registry by Lizz Paley, Claire Welsh, Sally Vernon, Mark Alan Green, Jennifer Lai, Catherine Welham, Jack Anderson, Clarice Quinn

“…We propose that this variable is now embedded into health inequalities reporting and adopted as the working definition of ‘coastal’ implicated in NHS England’s ‘Core20PLUS5’ approach for use in cancer data reporting.…”
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