Personalised prediction of maintenance dialysis initiation in patients with chronic kidney disease stages 3–5: a multicentre study using the machine learning approach by Usman Iqbal, Tzu-Hao Chang, Chu-Lin Chou, Mai-Szu Wu, Yung-Ho Hsu, Chih-Wei Huang, Anh Trung Hoang, Phung-Anh Nguyen, Thanh Phuc Phan, Gia Tuyen Do, Huu Dung Nguyen, I-Jen Chiu, Yu-Chen Ko, Chia-Te Liao

“…These findings have important implications for personalised treatment strategies, enabling improved clinical decision-making and potentially enhancing patient outcomes.…”
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Preoperative Gargling with Magnesium Sulphate versus Lignocaine on Postoperative Sore Throat in Patients Undergoing Surgery under General Anaesthesia: A Randomised Clinical Study by Jatin Patel, Yashvi Samir Patwa, Pooja Shah, Rajsi Shah, Sara Mary Thomas

“…These agents act through different mechanisms, with potential implications for intraoperative haemodynamic stability. …”
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Non-communicable diseases, psychosocial wellbeing, and quality of life in Ga Mashie, Accra, Ghana: analysis from a community-based cross-sectional study by Kafui Adjaye-Gbewonyo, Irene Akwo Kretchy, Leonard Baatiema, Carlos S. Grijalva-Eternod, Olutobi Adekunle Sanuade, Samuel Amon, Hassan Haghparast-Bidgoli, Raphael Baffour Awuah, Swaib Abubaker Lule, Sedzro Kojo Mensah, Sandra Boatemaa Kushitor, Mawuli Komla Kushitor, Daniel Kojo Arhinful, Edward Fottrell

“…This study sought to examine relationships between NCDs, quality of life (QoL) and psychosocial wellbeing in the urban community of Ga Mashie, Accra, Ghana. …”
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Identification of patients undergoing chronic kidney replacement therapy in primary and secondary care data: validation study based on OpenSAFELY and UK Renal Registry by Ben Goldacre, Dorothea Nitsch, Laurie A Tomlinson, Bang Zheng, Brian MacKenna, Amir Mehrkar, Lucy Plumb, Retha Steenkamp, Shalini Santhakumaran, Sebastian Bacon, Viyaasan Mahalingasivam, Caroline Morton, Louis Fisher, Edward PK Parker, Sue Lyon, Rob Konstant-Hambling

“…Linkage with UKRR kidney replacement therapy data facilitated more accurate identification of incident and prevalent kidney replacement therapy cohorts for research into this vulnerable population. Poor coding has implications for any patient care (including eligibility for vaccination, resourcing, and health policy responses in future pandemics) that relies on accurate reporting of kidney replacement therapy in primary and secondary care data.…”
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Assessment of knowledge, attitudes, and performance of postgraduate nursing students regarding clinical reasoning and evidence-based nursing: a multicenter cross-sectional study in... by Zahra Mohebi, Azizallah Dehghan, Ali Taghinezhad, Sorur Javanmardifard, Mostafa Bijani

“…Methods A descriptive cross-sectional multicenter study was undertaken from September through November 2024. …”
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Development of a machine learning-based model to predict urethral recurrence following radical cystectomy: a multicentre retrospective study and updated meta-analysis by Bo Fan, Luxin Zhang, Hepeng Cui, Shanshan Bai, Haifeng Gao, Shengxiang Xiang, Yuchao Wang, Zhuwei Song, Jiaqiang Chen, Guanghai Yu, Jianbo Wang, Liang Wang, Zhiyu Liu

“…Moreover, to benefit from the clinical implications of the predictive model, an easy-to-use risk calculator tool for UR was developed online ( https://zluxin.shinyapps.io/make_web/ ) based on the GBM model. …”
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Future Proofing Study: a cluster randomised controlled trial evaluating the effectiveness of a universal school-based cognitive–behavioural programme for adolescent depression by Maree Teesson, Helen Christensen, Svetha Venkatesh, Aliza Werner-Seidler, Lara Johnston, Bridianne O’Dea, Michelle Torok, Katharine Steinbeck, Raghu Lingam, Andrew Mackinnon, Yael Perry, Kit Huckvale, Joanne R Beames, Alison L Calear, Kate Maston, Philip J Batterham, Ju Lee Oei, Mark E Larsen, Jennifer L Hudson, Lyndsay Brown, Hiroko Fujimoto, Alexandra Batholomew, Debopriyo Bal, Susan Rachel Skinner, Katherine M Boydell, Susanne Schweizer

“…Secondary outcomes were change in anxiety, psychological distress and insomnia.Findings 134 schools participated in this study, and baseline data were collected from n=6388 students (n=3266 intervention; n=3122 control). …”
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Long COVID Symptoms and Five Dimensions of HRQoL: A Retrospective Regional Study of Patients Recovered from COVID-19 Infection in Saudi Arabia by Almoliky MA, Alsaif B, Saleh KA, Alkubati SA, Hassan SUN, Algahtani FD, Aldhmadi BKM, Assaggaf HM, Alzain MA

“…Among the long-COVID-19 symptoms, fatigue (p=0.05), persistent cough (p=0.001), dyspnea (p=0.02), and sexual dysfunction (p< 0.001) were the independent factors that impacted the HRQoL after controlling for background variables.Conclusion: The study has significant implications for Saudi Arabia’s Health Sector Transformation Program that could achieve its goals of human centric care and patient satisfaction though addressing the negative impacts of specific long-COVID symptoms such as fatigue, persistent cough, dyspnea and sexual dysfunction and improving the HRQoL in domains of pain/discomfort and anxiety/depression.Keywords: pandemic, healthcare, fatigue, pain, discomfort, anxiety, sexual dysfunction…”
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Endoscopic ultrasound-guided portosystemic pressure gradient measurement vs. transjugular balloon occlusion measurement in patients with cirrhosis (ENCOUNTER): A bicentric EU study by Emma Vanderschueren, Wim Laleman, Lawrence Bonne, Geert Maleux, David R. Wagner, Chyon Yeh, Andrea Calvo, Oriol Sendino, Angels Gines, Anna Baiges, Marco J. Bruno, Juan Carlos Garcia-Pagan, Schalk van der Merwe

“…However, attention must be paid to technical challenges, including the potential overestimation of EUS-guided hepatic vein pressures and the impact of general anesthesia, which may alter pressure measurements and subsequently affect risk classification. Impact and implications: The ENCOUNTER study is the first study to directly compare endoscopic ultrasound-guided portal pressure gradient (EUS-PPG) with hepatic venous pressure gradient (HVPG) in the same patients, simultaneously. …”
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Sexual distress with partnered face-to-face sexual activity: an exploratory qualitative study with heterosexual cis people who seek and do not seek professional help by Patrícia M. Pascoal, Patrícia M. Pascoal, Patrícia M. Pascoal, Patrícia M. Pascoal, Gerhard Andersson, Gerhard Andersson, Gerhard Andersson, Gerhard Andersson, Vinicius J. Fischer, Vinicius J. Fischer, Andreia A. Manão, Cátia Oliveira, Catarina F. Raposo, Catarina F. Raposo, Pedro J. Rosa, Pedro J. Rosa, Magda Sofia Roberto, Graça Santos, Nuno Tomada, Nuno Tomada, Annamaria Giraldi, Annamaria Giraldi

“…Participants’ accounts show that pre-existing psychological characteristics, partnered communication, cognitive, and emotional factors are key factors to shape the experience of sexual distress related to sexual dysfunctions. This has implications for clinical work as interventions should target transdiagnostic individual factors that may not be sexual specific (e.g., repetitive negative thinking) as well as couple-level factors (e.g., communication). …”
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The Barcelona baseline risk score to predict long-term prognosis after a first demyelinating event: a prospective observational studyResearch in context by Carmen Tur, Pere Carbonell-Mirabent, Susana Otero-Romero, Álvaro Cobo-Calvo, María Jesús Arévalo, Helena Ariño, Georgina Arrambide, Cristina Auger, René Carvajal, Joaquín Castilló, Manuel Comabella, Ingrid Galán, Luciana Midaglia, Carlos Nos, Agustín Pappolla, Deborah Pareto, Jordi Río, Breogán Rodríguez-Acevedo, Estibaliz Saez de Gordoa, Ángela Vidal-Jordana, Ana Zabalza, Jaume Sastre-Garriga, Àlex Rovira, Xavier Montalban, Mar Tintoré

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Ethiopian women experiencing infertility: sociocultural challenges and coping strategies by Tinisaie Biadigie Adane, Kelemu Zelalem Berhanu, Abatihun Alehegn Sewagegn

“…This study has theoretical implications for current literature knowledge and practical implications.…”
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Exploring the Acceptance and Opportunities of Using a Specific Generative AI Chatbot to Assist Parents in Managing Pediatric Rheumatological Chronic Health Conditions: Mixed Method... by Cheryl W Y Lau, Klaudia Kupiec, Polly Livermore

“…MethodsThis study was a mixed methods design, using both a family workshop and a subsequent questionnaire. …”
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Unhiding female characters in the parable of the sower: Reimagining fields and farms by Charel D. du Toit, Ernest van Eck

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Biostratigraphy and Microfacies of Upper Cretaceous Oceanic Red Beds in the Northern Tethyan Himalaya: A Case Study from the Zhangguo Section, Gyangze, Southern Tibet, China by Yuewei Li, Guobiao Li, Jie Ding, Dan Xie, Tianyang Wang, Zhantu Baoke, Mengmeng Jia, Chengshan Wang

“…The Cretaceous oceanic red beds (CORBs) and their implications for “oceanic oxic events” have been widely studied by geologists globally. …”
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Minor surgical procedures during immune tolerance induction in people with hemophilia A and inhibitors: results from the Brazilian Immune Tolerance (BrazIT) study cohort by Ricardo Mesquita Camelo, Maíse Moreira Dias, Suely Meireles Rezende

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Association between C677T and A1298C MTHFR gene polymorphism and nonsyndromic orofacial clefts in the Turkish population: a case-parent study by Aida Semiç-Jusufagiç, Rıfat Bircan, Özhan Çelebiler, Melike Erdim, Nurten Akarsu, Nursel H Elçioğlu

“… Two common MTHFR gene polymorphisms (C677T and A1298C) have been implicated in the etiology of nonsyndromic cleft lip/palate (nsCL/P). …”
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Do floods affect food security? A before-and-after comparative study of flood-affected households’ food security status in South-Eastern Nigeria by Akukwe Thecla Iheoma, Oluoko-Odingo Alice Atieno, Krhoda George Okoye

“…A comparative study of pre- and post-flood households’ food security statuses in South-Eastern Nigeria was performed to answer the question “Do floods affect food security?” …”
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A prospective hospital-based study on C-reactive protein as a response predictor of antidepressant treatment in drug naïve patients with major depressive disorder by Didakamiwan Khonglah, Arghya Pal, Nitu Mallik, Debes Ray, Malay Ghosal, Rudraprasad Acharya

“…Aims: This study was conducted to determine the relationship between the level of CRP to remission rates after antidepressant therapy. …”
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The mediating role of self-efficacy and the moderating impact of organizational climate: a case study for improving teacher well-being through leadership and meaningful work by Wahyudi Triwiyanto, Fathur Rokhman, Joko Sutarto, Tri Suminar

“…Methodology: This study used a quantitative research approach with an exploratory design. …”
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