Acute gabapentin administration in healthy adults. A double-blind placebo-controlled study using transcranial magnetic stimulation and 7T 1H-MRS by Katherine Dyke, Sophia E. Pépés, Ben Babourina-Brooks, Chen Chen, Soyoung Kim, Hilmar P. Sigurdsson, Amelia Draper, Masud Husain, Parashkev Nachev, Penny Gowland, Peter G. Morris, Stephen R. Jackson

“…These findings have implications for the use of acute GBP dosing as a means to explore GABAergic function in health and disease.…”
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The Relationship of Attitudes toward Other Religious Groups with Perceived Islamophobia, Intergroup Contact, and Social Identity: A Study among Muslims Living in Western Countries by Kenan Sevinç, Metin Güven

“…Results indicated that (a) Catholics are the most positively regarded religious group for Muslims and they are the group with whom Muslims have the highest frequency of contact; (b) attitudes toward other religious groups were associated with frequency of contact and positive evaluation of contact; (c) there was no statistical relationship between levels of social identification, contact and perceived Islamophobia and attitudes towards other religious groups, and (d) among religious groups, perceived Islamophobia was only associated with attitudes toward Jews and evaluations of contact with this group. We discuss the study implications, limitations as well as future research avenues.…”
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Comparing Different Contrast Injection Methods for Multislice Spiral CT Imaging in Triple-Rule-Out Examinations: A Study on Acute Chest Pain Patients by Meng Y, Li F, Gu Y, Zhou Y, Zhang Y, Liu Y, Miao Z

“…This approach shows valuable potential for improving both the safety and effectiveness of TRO-CTA, with significant implications for clinical practice.Keywords: triple-rule-out computed tomography angiography, chest pain, contrast injection methods…”
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Implementing peer support work in mental health care in Germany: The methodological framework of the collaborative, participatory, mixed‐methods study (ImpPeer‐Psy5) by Sebastian vonPeter, Ute Maria Kraemer, Lauren Cubellis, Georgia Fehler, Guillermo Ruiz‐Pérez, Daniela Schmidt, Jenny Ziegenhagen, Madeleine Kuesel, Susanne Ackers, Candelaria Mahlke, Lena Nugent, Imke Heuer

“…Discussion and Practical Implications The healthcare, policy and funding context of PSW implementation as well as the study's methodological framework have differently influenced the ways in which the implementation of PSW has been conceived in this study. …”
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Near-infrared spectroscopy combined with vascular occlusion test to predict acute kidney injury in patients undergoing cardiac surgery: a prospective observational study by Ling Peng, Yeying Zheng, Fei Guo, Mengdan Su, Wei Wei

“…This study aimed to investigate the association between StO2-VOT measurements and the occurrence of postoperative acute kidney injury (AKI), in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). …”
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Improving Virological Monitoring of HDV Infection: A Proof-of-Concept Comparative Study of Bosphore and AltoStar^® Assays in Patients Treated with Bulevirtide by Verdiana Zulian, Chiara Taibi, Antonio Coppola, Angela Bibbò, Luigi Federici, Martina De Sanctis, Silvia Pauciullo, Gianpiero D’Offizi, Elisa Biliotti, Fiona McPhee, Anna Rosa Garbuglia

“…Accurate measurement of HDV RNA is critical for monitoring therapeutic responses, especially during treatment with novel therapies such as bulevirtide (BLV). This study compared the analytical performance of two HDV RNA quantification assays, Bosphore (Anatolia) and AltoStar^® (Altona), focusing on their sensitivity, specificity, and potential implications for clinical management. …”
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‘Living with Covid’: Well-being, Burnout, and Moral Injury in England’s Adult Social Care Workforce – A Survey Study by Sue Davies, Amelia Pearson, Rosie Allen, William Whittaker, Patricia Cartney, Paul Clarkson, Rebecca McPhillips, Janine Owens, Martyn Regan, Martie Van Tongeren, Alys Young, Catherine Robinson

“…Implications: The findings highlight the importance of adequate resources and infection control measures in reducing harm in the adult social care workforce and building resilience for future sector pressures. …”
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Distribution and Antimicrobial Resistance Analysis of Blood Culture Isolates at a Chinese National Cardiovascular Regional Medical Center: A 7-Year Retrospective Study by Wang Q, Wu F, Li T

“…Qian Wang, Fan Wu, Tao Li Department of Medical Laboratory, Fuwai Central China Cardiovascular Hospital/Central China Fuwai Hospital of Zhengzhou University/Henan Provincial People’s Hospital, Zhengzhou, Henan, 451464, People’s Republic of ChinaCorrespondence: Tao Li, Department of Medical Laboratory, Fuwai Central China Cardiovascular Hospital/Central China Fuwai Hospital of Zhengzhou University/Henan Provincial People’s Hospital, Zhengzhou, Henan, 451464, People’s Republic of China, Email zzlitao@zzu.edu.cnPurpose: This study aimed to characterize the epidemiological patterns and antimicrobial resistance profiles of bloodstream infections (BSIs) in a cardiovascular specialty hospital and to identify region-specific pathogen distributions, resistance risks, and clinical implications for optimizing empirical therapy and infection control strategies.Patients and Methods: A retrospective analysis (2018– 2024) evaluated 1,055 non-duplicate BSI isolates from 37,576 blood cultures at the Fuwai Central China Cardiovascular Hospital. …”
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Applying the theoretical domains framework to identify determinants to mental healthcare use among older African Americans with type 2 diabetes: a qualitative study by Jamie Mitchell, Jaclynn Hawkins, Srijani Sengupta, Katherine A Kloss, Claudia Schwenzer, Fonda N Smith, Lenette M Jones, Robin Nwankwo, Gretchen A Piatt

“…Objectives There is a paucity of research focused on enhancing access to mental healthcare for older African Americans with type 2 diabetes (T2D), who may be at risk for or living with comorbid depression. This study aims to identify barriers and facilitators to mental healthcare utilisation among this population, guided by the theoretical domains framework (TDF).Design This qualitative study involved 30 interviews with older African American adults diagnosed with T2D. …”
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“Why shouldn’t I expect a lot from life?” – a qualitative study of what facilitates long-term recovery in first-episode psychosis by Gina Åsbø, Hanne Haavind, Sindre Hembre Kruse, Kristin Fjelnseth Wold, Wenche ten Velden Hegelstad, Kristin Lie Romm, Mike Slade, Torill Ueland, Ingrid Melle, Carmen Simonsen

“…Methods Interviews with 20 individuals in recovery (personal and/or clinical) participating in two follow-up studies, 10 and 20-years after treatment start for a first episode schizophrenia or bipolar spectrum disorder. …”
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Discrepancies in Peripheral Arterial Function Indices Among Healthy Young Black Africans: Findings from Pilot Study Interpreted Using AHA Reference Values by Tuntufyege Erasto Mwasanjobe, Ashabilan Ebrahim, Oscar Mbembela, Omary Chillo, Jacktan Josephat Ruhighira, Fredirick Mashili

“…These findings highlight the need to carefully interpret ABI results in young populations and emphasize the importance of concurrent ABI and PVW measurements. Larger studies are warranted to refine population-specific reference ranges and explore right–left differences' physiological and clinical implications.…”
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Parent-Reported Burn-Specific Health-Related Quality of Life in Children 5–7 Years After Burns: A Multicenter Cross-Sectional Study by Marina C. Heijblom, J. Nicolaas Dijkshoorn, Marianne K. Nieuwenhuis, Anouk Pijpe, Cornelis H. van der Vlies, Margriet E. van Baar, Inge Spronk

“…Surviving a burn can dramatically alter a child’s life, yet few studies examined long-term health-related quality of life (HRQL). …”
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Political rationale, aims, and outcomes of health-related high-level meetings and special sessions at the UN General Assembly: A policy research observational study. by Paolo Rodi, Werner Obermeyer, Ariel Pablos-Mendez, Andrea Gori, Mario C Raviglione

“…Thus far, the HIV/AIDS UNGASS was the only one followed by a level of commitment that has likely contributed to the reversal of the previous burden trend. Limitations of this study include its global perspective and aerial view that cannot discern the effects at the country level. …”
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Enhancing Genomic Prediction Accuracy with a Single-Step Genomic Best Linear Unbiased Prediction Model Integrating Genome-Wide Association Study Results by Zhixu Pang, Wannian Wang, Pu Huang, Hongzhi Zhang, Siying Zhang, Pengkun Yang, Liying Qiao, Jianhua Liu, Yangyang Pan, Kaijie Yang, Wenzhong Liu

“…To overcome this limitation, we integrate results from genome-wide association studies (GWAS) into an enhanced ssGBLUP framework, termed single-step genome-wide association assisted BLUP (ssGWABLUP). …”
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The association between multimorbidity and mobility disability-free life expectancy in adults aged 85 years and over: A modelling study in the Newcastle 85+ cohort. by Laurie E Davies, Stewart W Mercer, Katie Brittain, Carol Jagger, Louise Robinson, Andrew Kingston

“…Data were drawn from the Newcastle 85+ Study: a longitudinal population-based cohort study that recruited community-dwelling and institutionalised individuals from Newcastle upon Tyne and North Tyneside general practices. …”
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Exploring the Views of Dermatologists, General Practitioners, and Melanographers on the Use of AI Tools in the Context of Good Decision-Making When Detecting Melanoma: Qualitative... by Brad Partridge, Nicole Gillespie, H Peter Soyer, Victoria Mar, Monika Janda

“…ConclusionsClinicians conceptualized AI support in an array of disparate ways that have implications for how AI should be incorporated into clinical workflows. …”
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Evaluating a brief imagery-based intervention for adolescent depression: study protocol for a Phase IIB randomised control trial (INDIGO) in secondary schools by Victoria Pile, Rose Tinch-Taylor, Ben Carter, Jessica Richardson, Lisa De Rijk, Mary Leamy, Simon E. Blackwell, Richard Meiser-Stedman, Barnaby D. Dunn, Sarah Byford, Emily A. Holmes, Cathy Creswell, Patrick Smith

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Application of ventilator-associated events (VAE) in ventilator-associated pneumonia (VAP) notified in Brazil (IMPACTO MR-PAV): a protocol for a cohort study by Alvaro Avezum, Adriano José Pereira, Viviane C Veiga, Haliton Alves De Oliveira Junior, Giovanna Marssola Nascimento, Daniela Laranja Gomes Rodrigues, Daniela Ghidetti Mangas Catarino, Filipe Teixeira Piastrelli, Maysa Yukari Cheno, Katia Cristina Camonda Braz, Lucas Bassolli Oliveira Alves, Alexandre Prehn Zavascki, Bruno Tomazini, Bruno Besen, Ana Paula Neves Marques de Pinho

“…The results will contribute to the improvement of VAP surveillance in Brazil and may have implications for other countries that use similar criteria.Trial registration number NCT05589727; Clinicaltrials.gov.…”
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Cost-effectiveness of leveraging existing HIV primary health systems and community health workers for hypertension screening and treatment in Africa: An individual-based modeling s... by Matthew D Hickey, James Ayieko, Jane Kabami, Asiphas Owaraganise, Elijah Kakande, Sabina Ogachi, Colette I Aoko, Erick M Wafula, Norton Sang, Helen Sunday, Paul Revill, Loveleen Bansi-Matharu, Starley B Shade, Gabriel Chamie, Laura B Balzer, Maya L Petersen, Diane V Havlir, Moses R Kamya, Andrew N Phillips

“…<h4>Methods and findings</h4>We conducted a modeling study to simulate hypertension and CVD across 3,000 scenarios representing a range of settings across eastern, southern, central, and western Africa. …”
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Inequalities in the practice of physical activity in the city of São Paulo between 2003 and 2015: Evidence from a population-based study among older adults by Bruno Holanda Ferreira, Camila Nascimento Monteiro, Tatiane Kosimenko Ferrari Figueiredo, Margareth Guimarães Lima, Chester Luiz Galvão Cesar, Moisés Goldbaum, Olinda do Carmo Luiz

“…However, sociodemographic factors influence physical activity levels, leading to disparities in access and adherence. This study aimed to analyze changes in the frequency of physical activity and sociodemographic inequalities among older adults living in Brazil, using data from two health surveys. …”
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