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8421
“I don’t think there’s necessarily a one size fits all” negotiating competing priorities in nurse shift scheduling: a qualitative study
Published 2025-08-01“…These findings have significant implications for improving the sustainability and quality of healthcare service provision.…”
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8422
Tailored Anti-VEGF Therapy with New Generation Optimizations (TANGO) Treatment Regimen for Neovascular Age-Related Macular Degeneration: Rationale, Design, and Simulation Study
Published 2025-04-01“…However, it should be emphasized that this is a descriptive report and a simulation study, and clinical real-world studies of efficacy and safety using TANGO are warranted to better understand implications of employing TANGO in routine clinical practice.Keywords: neovascular age-related macular degeneration, anti-VEGF, treatment regimen, faricimab, aflibercept, tailored anti-VEGF therapy with new generation optimizations…”
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8423
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8424
A cross-sectional study of the experiences of distressed callers when accessing financial assistance from a telephone-based cancer information and support service
Published 2024-12-01“…Objective: The objective of this study was to explore the experiences of distressed people calling helplines regarding offer and uptake of financial services after cancer diagnosis. …”
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8425
Addressing Spatial Variability in Estimating Cover Management Factor of Soil Erosion Models using Geoinformatics: A Case Study of Netravati Catchment, Karnataka, India
Published 2025-07-01“…Apart from highlighting the need for local parameterisation, the results have important implications for soil conservation planning, erosion risk management, and sustainable land use practices in the region.…”
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8426
Debris flows dynamic risk assessment and interpretable Shapley method-based driving mechanisms exploring – A case study of the upper reach of the Min River
Published 2025-04-01“…These findings have implications for debris flow mitigation and contribute to the understanding of the multiple factors that impact debris flow risk.…”
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8427
Seeing it from both sides: do approaches to involving patients in improving their safety risk damaging the trust between patients and healthcare professionals? An interview study.
Published 2013-01-01“…<h4>Design</h4>Qualitative study, using purposive sampling and semi-structured interviews with patients, their relatives and healthcare professionals. …”
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8428
Article RETRACTED due to manipulation by the authors Application of Circuit Training Methods to Improve VO2max Physical Condition: An Experimental Study on Handball Athletes
Published 2024-05-01“…The implications of this study can be useful in designing a more focused training program to improve the performance of handball athletes through a training approach that suits their physiological needs. …”
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8429
Investigation of mRNA expression levels of DNA damage response genes in Merkel Cell Polyomavirus-positive Merkel Cell Carcinoma: a pilot study
Published 2025-05-01“…Our findings support the established viral aetiology of MCC, and describe, for the first time, an over-expression of DDR components in MCPyV-positive MCC, laying the basis for future studies aimed at investigating the contribution of this pathway to MCPyV-mediated carcinogenesis and exploring the plausible clinical implications of host DDR factors for the treatment of MCC.…”
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8430
Effects of home-based, low-intensity exergaming on cognitive function of individuals with mild cognitive impairment: a study protocol for a randomized controlled trial
Published 2025-06-01“…Discussion The findings of this study might provide valuable insights into an effective and practical intervention program aimed at improving cognitive function of older adults with MCI. …”
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8431
Diagnostic accuracy of cartridge-based nucleic acid amplification test and resistance pattern in new and previously treated tuberculosis cases: A prospective observational study
Published 2024-06-01“…However, further research is needed to validate these results and evaluate the clinical implications of using CBNAAT in routine TB diagnostics.…”
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8432
Prognostic value of c-MET in oesophageal squamous cell carcinoma: a study based on the mRNA expression in TCGA database and a meta-analysis
Published 2025-02-01“…Meta-analysis findings indicated that high c-MET expression was associated with worse OS (HR = 1.54, 95% confidence interval [CI]: 1.17–2.01; p = 0.002), distant metastasis (OR = 1.97, 95% CI: 1.14–3.40; p = 0.02) and advanced stage (OR = 2.23, 95% CI: 1.41–3.53; p = 0.0006).ConclusionHigh c-MET expression is associated with poor prognosis and advanced disease in ESCA, highlighting its potential as a biomarker for risk stratification. Further studies are needed to confirm its prognostic value and explore therapeutic implications.…”
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8433
Self-assessed levels of preparedness, engagement willingness and teaching preferences on antibiotic use of medical and pharmacy students in Romanian universities: a cross-sectional...
Published 2024-10-01“…Most of both medical and pharmacy students considered the antibiotic situation in Romania ‘will get worse’ (n = 159, 33.5%). Conclusions The study’s findings have important implications for the education and training of future Romanian health professionals and highlight the need for further research on optimal and standardized tools to allow for periodic monitoring and evaluation of progress into preparedness, engagement willingness and teaching preferences on antibiotic use.…”
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8434
Dementia risk estimation in persons at risk and the predictive turn in Alzheimer's disease-The PreTAD project: Study protocol with an ethical, clinical, linguistic, and legal appro...
Published 2025-01-01“…The study was registered in the German Clinical Trials Register (DRKS00029035 on 03/08/2023).…”
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8435
Unfavorable Outcomes and Their Risk Factors in Hospitalized Patients with <i>Staphylococcus aureus</i> Bacteremia in the US: A Multicenter Retrospective Cohort Study, 2020–2022
Published 2025-03-01“…A broader perspective exploring issues other than mortality demonstrates the substantial implications of SAB both for patients and healthcare systems. …”
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8436
Exploring secular trends and types of tuberculosis burden in India over past three decades through insights from the Global Burden of Disease Study 2019
Published 2025-07-01“…Data and methods This study leverages data from the Global Burden of Disease Study 2019. …”
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8437
The Effects of Strata Orientation and Water Presence on the Stability of Engineered Slopes Using DIPS and FLACSlope: A Case Study of Tubatse and Fetakgomo Engineered Road Slopes
Published 2024-10-01“…This paper combines empirical observations, kinematic analysis, and numerical simulation to investigate slope failure susceptibility, with practical implications for regional infrastructure projects. Six slopes along the R37 road were analyzed to assess the impact of strata orientation and water presence on slope stability. …”
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8438
Ambivalent User Needs as a Challenge and Chance for the Design of a Web-Based Intervention for Gaming Disorder: Qualitative Interview Study With Adolescents and Young Adults
Published 2025-05-01“…ObjectiveThe aim of this study was to explore the treatment needs of young people with GD in Germany and derive implications for the development of a self-guided WBI for GD. …”
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8439
Ageing workers’ mental health during COVID-19: a multilevel observational study on the association with the work environment, perceived workplace safety and individual factors
Published 2022-12-01“…Objectives The stress and anxiety associated with the predisposition of ageing workers to severe COVID-19 illness, once occupationally infected, jeopardise their mental health. This study aimed to investigate the association between individual level, work environment exposure factors and perceived workplace safety with a decline in mental health of ageing workers from different industry sectors.Design Observational study, prevalence assessment of survey added to longitudinal cohort data.Setting The Survey of Health, Ageing and Retirement in Europe (SHARE) from 27 countries in Europe and Israel participating in the COVID-19 survey (summer 2020) and having prepandemic waves’ SHARE data.Participants Workers aged 50–70 (n=6449) who attended their workplaces at least partially after the pandemic broke out.Primary outcome measure Perceived decline in mental health compared with preoutbreak status.Results Multilevel analyses demonstrated that 24.5% (95% CI 23.5% to 25.5%) of ageing workers in Europe experienced mental health decline associated with national-level self-reported COVID-19 burden. …”
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8440
Associations Among Minority Stress, Allostatic Load, and Drug and Alcohol Use in Sexual Minorities: Protocol for the Queer Health Study—a Longitudinal Feasibility Evaluation
Published 2025-06-01“…A total of 40 ethnically and racially diverse sexual minority adult participants (aged 18-60 years) will be enrolled. ResultsThe study received University of Houston institutional review board approval on July 31, 2023 (STUDY00004277). …”
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