Transcriptomic-based analysis of endometrial tissues from adenomyosis patients reveals significant inflammation biomarkers: A bioinformatics study by Marni Sianturi, Alauddin Syaifulanwar, Darmawi Darmawi, Wirawan Adikusuma, Lalu Muhammad Irham, Muhammad Yusuf, Rifia Tiara Fani, Febriani Febriani

“…Materials and Methods: In this bioinformatics study, we utilized publicly available transcriptomic datasets. …”
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‘QuickDASH’ to find unique genes and biological processes associated with shoulder osteoarthritis: a prospective case–control study by Samuel J. Lynskey, Stephen D. Gill, Sean L. McGee, Mark Ziemann, Richard S. Page

“…Key pathways involved interleukins, chemokines, complement components, nuclear response factors, and immediate early response genes, reflecting a balance between pro- and anti-inflammatory signalling. Additionally, this study identified unique gene expression patterns in shoulder OA not previously observed in hip and knee OA, along with novel genes implicated in shoulder OA, highlighting areas for future targeted investigation. …”
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The MCP‐1 rs1024611 and MTHFR rs1801133 gene variations and expressions in alopecia areata: A pilot study by Pardis‐Sadat Tabatabaei‐Panah, Hamideh Moravvej, Mahsa Hajihasani, Mahsa Mousavi, Ralf J. Ludwig, Reza Akbarzadeh

“…Conclusion In summary, despite MCP‐1 rs1024611 and MTHFR rs1801133 variations are not associated with AA risk, they may implicate the disease pathogenesis by influencing MCP‐1 activity.…”
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Sex-specific association between serum α-klotho levels and sleep disturbances in the elderly: a cross-sectional study by Lu Liu, Tao Xu, Xiaolan Gao, Xianying Lei, Qinxue Hu

“…Conclusions The findings of the current study revealed a negative association between α-klotho levels and the development of SD in the elderly population, with notable sex-specific differences.…”
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Assessment of medication-related liver and kidney impairment in admitted patients in Depok, Indonesia: an observational study employing the Naranjo algorithm by Nadia Farhanah Syafhan, Ghea Shafa Aldora, Shinta Kamila

“…Implementing strategies to recognize, document, and analyze cases of patient harm related to drug use is crucial for medicines optimization. This study aimed to evaluate the prevalence of medication-related liver and kidney impairment among hospitalized patients, while also identifying the specific medication categories implicated. …”
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Interleukin-6 as a Predictive Marker for Lymph Node and Distant Metastasis in Colorectal Cancer: A Retrospective Cohort Study by Xiao J, Tian M, Chen G, Li H

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Numerical Study of the Condenser of a Small CO₂ Refrigeration Unit Operating Under Supercritical Conditions by Piotr Szymczak, Piotr Bogusław Jasiński, Marcin Łęcki

“…One of the most important conclusions is the discovery of a significant effect of water velocity on heat transfer from the CO₂ side—an increase in water velocity from 0.5 m/s to 2 m/s results in an increase in the heat transfer coefficient sCO₂ by over 60%, with the same Re number. The implication of this study is to show the possibility of adjusting and selecting condenser parameters over a wide range of capacities, just by changing the fluid velocity.…”
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Cave morphology and moonmilk deposits of Ryongmun Cavern, Democratic People’s Republic of Korea: A Study for the Conservation of Natural Heritage by Won–Sok Jon, To-Jun Ryang, Hyon Hwangbo

“…The unique underground karst features provide sufficient evidence for geoheritage value of the cave and the characteristics of moonmilk provide a significant implication for management and preservation of the cave environment.…”
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Exploring the mechanism of berberine treatment for atherosclerosis combined with non-alcoholic fatty liver disease based on bioinformatic and experimental study. by Shushu Wang, Kachun Lu, Liwen Lin, Gaijie Li, Yuxin Han, Zhichao Lin, Qingmin Chu, Kunsheng Wu, Peijian Liu, Guiting Zhou, Rui Peng, Chuanjin Luo

“…Through transcriptome analysis, WGCNA, and machine learning, this study identified 48 key genes involved in both AS and NAFLD. …”
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Associations with the inter-recti distance at gestation week 37: a prospective cohort study among healthy pregnant women by Nina-Margrethe Theodorsen, Rolf Moe-Nilssen, Kari Bø, Inger Haukenes

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The environment as an unrecognized reservoir for community-associated methicillin resistant Staphylococcus aureus USA300: a case-control study. by Anne-Catrin Uhlemann, Justin Knox, Maureen Miller, Cory Hafer, Glenny Vasquez, Megan Ryan, Peter Vavagiakis, Qiuhu Shi, Franklin D Lowy

“…<h4>Methods</h4>We carried out a community-based, case-control study investigating socio-demographic risk factors and infectious reservoirs associated with MRSA infections. …”
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PHARMACOVİGİLANCE OF DRUG-INDUCED LEUKEMİA: A DESCRİPTİVE STUDY OF FDA ADVERSE EVENT REPORTİNG SYSTEM FROM 1969-2024 by Ahmet Sarici, Lokman Hekim Tanriverdi

“…Background: Drug-induced leukemia is a recognized adverse drug reaction associated with specific classes of medications. This study aims to quantify the frequency of leukemia-related adverse drug reactions and identify the medications most implicated as potential causes in the FDA Adverse Event Reporting System (FAERS). …”
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Potential biomarkers for predicting the risk of thyroid cancer in immunosenescence: a population-based and externally validated multi omics study by Qian Li, Yuanyuan Zhao, Jiawei Yan, Chao He

“…ObjectivesGenome-wide association studies (GWAS) have pinpointed several risk loci linked to thyroid cancer; however, the discovery of new plasma proteins implicated in immunosenescence continues to pose significant challenges. …”
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Association of alpha-1 acid glycoprotein with hepatic steatosis and liver fibrosis among women: a population-based study by Sichang Wang

“…Abstract Background and aim The alpha-1-acid glycoprotein (AGP) is a novel inflammatory biomarker, and inflammation has been implicated in hepatic steatosis and fibrosis. The objective of this study was to investigate the relationship between AGP and hepatic steatosis and hepatic fibrosis and to assess its value as a potential biomarker. …”
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Genome-wide association study identifies candidate SNP markers and genes associated with low nitrogen tolerance in Brassica napus by Jingdong Chen, Jingdong Chen, Lingli Xie, Xianfei Hou, Rui Yang, Jin Liu, Xigang Dai, Tianyuan Xue, Shuai Yin, Benbo Xu, Xuekun Zhang, Changli Zeng, Jinsong Xu

“…Several genes such as NPF2.10, ATG4a, and AATL1 were implicated in nitrogen uptake, transport, remobilization, and stress adaptation. …”
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Talus Position Correlates With Dorsiflexion Range of Motion Following a Lateral Ankle Sprain: A Cross‐Sectional Study by Takeshi Toyooka, Eiki Tsushima, Shiro Sugiura, Yukio Matsushita, Akito Takata, Yasutaka Omori, Yuzuru Okamoto, Satoru Nishikawa

“…ABSTRACT Background and Aims Following an ankle sprain, clinical examination often reveals ankle dorsiflexion pain, which has been implicated as a risk factor for recurrent ankle sprains; however, the mechanism of ankle dorsiflexion pain has not been explored. …”
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Prostate cancer incidence and mortality among immigrants in Finland between 2000 and 2017 – a register-based cohort study by Katja M. Mustonen, Maarit H. Lamminmäki, Tytti M. Sarkeala, Sirpa H. Heinävaara

“…While uncertain, this implication is concerning enough to warrant further research into the topic. …”
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NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. by Nancy L Heard-Costa, M Carola Zillikens, Keri L Monda, Asa Johansson, Tamara B Harris, Mao Fu, Talin Haritunians, Mary F Feitosa, Thor Aspelund, Gudny Eiriksdottir, Melissa Garcia, Lenore J Launer, Albert V Smith, Braxton D Mitchell, Patrick F McArdle, Alan R Shuldiner, Suzette J Bielinski, Eric Boerwinkle, Fred Brancati, Ellen W Demerath, James S Pankow, Alice M Arnold, Yii-Der Ida Chen, Nicole L Glazer, Barbara McKnight, Bruce M Psaty, Jerome I Rotter, Najaf Amin, Harry Campbell, Ulf Gyllensten, Cristian Pattaro, Peter P Pramstaller, Igor Rudan, Maksim Struchalin, Veronique Vitart, Xiaoyi Gao, Aldi Kraja, Michael A Province, Qunyuan Zhang, Larry D Atwood, Josée Dupuis, Joel N Hirschhorn, Cashell E Jaquish, Christopher J O'Donnell, Ramachandran S Vasan, Charles C White, Yurii S Aulchenko, Karol Estrada, Albert Hofman, Fernando Rivadeneira, André G Uitterlinden, Jacqueline C M Witteman, Ben A Oostra, Robert C Kaplan, Vilmundur Gudnason, Jeffrey R O'Connell, Ingrid B Borecki, Cornelia M van Duijn, L Adrienne Cupples, Caroline S Fox, Kari E North

“…The NRXN3 gene has been previously implicated in addiction and reward behavior, lending further evidence that common forms of obesity may be a central nervous system-mediated disorder. …”
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Ciclosporin A proof of concept study in patients with active, progressive HTLV-1 associated myelopathy/tropical spastic paraparesis. by Fabiola Martin, Hannah Castro, Carolyn Gabriel, Adine Adonis, Alexandra Fedina, Linda Harrison, Liz Brodnicki, Maria A Demontis, Abdel G Babiker, Jonathan N Weber, Charles R M Bangham, Graham P Taylor

“…Tested antiretroviral therapies have not been effective and most patients are offered a short course of corticosteroids or interferon-α, physiotherapy and symptomatic management. Pathogenesis studies implicate activated T-lymphocytes and cytokines in tissue damage. …”
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Prevalence and clinical significance of potential drug-drug interactions of antimicrobials in Intensive Care Unit patients: a retrospective study by Shanshan Xu, Zhihui Song, Jie Bai, Jiawei Wang

“…Methods We conducted a retrospective study on patients admitted to intensive care units from January to December 2023. …”
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