Association of electrocardiogram alterations of rescuers and performance during a simulated cardiac arrest: A prospective simulation study. by Lucas Tramèr, Christoph Becker, Seraina Hochstrasser, Stephan Marsch, Sabina Hunziker

“…<h4>Background</h4>Performance of cardiopulmonary resuscitation (CPR) causes significant mental stress for rescuers, especially if performed by inexperienced individuals. Our aim was to study electrocardiogram (ECG) alterations in rescuers and its association with gender and CPR performance.…”
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Predictors of in-hospital mortality in critically ill patients with COVID-19: a large dual tertiary centre study by Divaka Perera, Georgios Georgiopoulos, Hannah Sinclair, Matthew Ryan, Kevin O’Gallagher, Alexandros Papachristidis, Mark Monaghan, Ajay M Shah, Gerald Carr-White, Ozan M Demir, Mark Zuckerman, Andrew Osborne, Alina Hua, Richard Fisher, Peter Pearson, Kelly Victor, Vasileios Stylianidis, Eleanor Corcoran, Chiara Cirillo, Eleni Nakou, Christos Tountas, Apostolia Marvaki, Nishita Desai, Ana Pericao, Anender Dhariwal, Adam Abner Nabeebaccus, Tiago Fonseca, Eva Toth

“…Objectives The aim of this study was to investigate the relationship of echocardiographic parameters, laboratory findings and clinical characteristics with in-hospital mortality in adult patients with COVID-19 admitted to the intensive care units (ICU) in two large collaborating tertiary UK centres.Design Observational retrospective study.Setting The study was conducted in patients admitted to the ICU in two large tertiary centres in London, UK.Participants Inclusion criteria were: (1) patients admitted to the ICU with a COVID-19 diagnosis over a period of 16 weeks. and (2) underwent a transthoracic echocardiogram on the first day of ICU admission as clinically indicated.No exclusion criteria applied.Three hundred patients were enrolled and completed the follow-up.Primary and secondary outcome measures The outcome measure in this study was in-hospital mortality in patients admitted to the ICU with COVID-19 infection.Results Older age (HR: 1.027, 95% CI 1.007 to 1.047; p=0.008), left ventricular (LV) ejection fraction&lt;35% (HR: 5.908, 95% CI 2.609 to 13.376; p&lt;0.001), and peak C reactive protein (CRP) (HR: 1.002, 95% CI 1.001 to 1.004, p=0.001) were independently correlated with mortality in a multivariable Cox regression model. …”
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Toxoplasma gondii in dromedary camels (Camelus dromedarius) in Egypt: a comparative seroepidemiological study in Upper and Lower Egypt by Ehab Kotb Elmahallawy, Ehab Kotb Elmahallawy, Nady Khairy Elbarbary, David Cano-Terriza, David Cano-Terriza, Tomás Fajardo, Nada Oudah Albalawi, Débora Jiménez-Martín, Marwa M. I. Ghallab, Ahmed Gareh, Refaat Ras, Refaat Ras, Isabelle Villena, Sabry A. S. Sadek, Hajar AlQadeeb, Hind Alzaylaee, Sonia Almería, Ignacio García-Bocanegra, Ignacio García-Bocanegra

“…The global information available regarding the role of camels in the epidemiology of Toxoplasma gondii is still limited. This study aimed to assess the seroprevalence of T. gondii in dromedary camels (Camelus dromedarius) from northern and southern Egypt. …”
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Second-line pembrolizumab for advanced HCC: Meta-analysis of the phase III KEYNOTE-240 and KEYNOTE-394 studies by Richard S. Finn, Kangsheng Gu, Xi Chen, Philippe Merle, Kyung-Hun Lee, Mohamed Bouattour, Peiguo Cao, Wei Wang, Ann-Lii Cheng, Liangjun Zhu, Ho Yeong Lim, Masatoshi Kudo, Yueyin Pan, Ting-Tsung Chang, Julien Edeline, Wei Li, Ping Yang, Chen Li, Jianfeng Li, Abby B. Siegel, Shukui Qin

“…Impact and implications: To obtain a more precise estimate of the pembrolizumab treatment effect in participants with previously treated advanced hepatocellular carcinoma, we performed a meta-analysis of efficacy using pooled participant data from the phase III KEYNOTE-240 and KEYNOTE-394 studies. …”
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Mediation analysis of antidepressant use, depressive symptoms, and recurrent falls in community-dwelling older fallers: An exploratory study by Adson da Silva Passos, PhD, Adriana Sanudo, PhD, Érika Yukie Ishigaki, MSc, Maria Aquimara Zambone Magalhães, MSc, Silvana Barbosa Pena, PhD, Andreia Cristina Feitosa do Carmo, MSc, Sérgio Márcio Pacheco Paschoal, PhD, Monica Rodrigues Perracini, PhD, Luiz Eugênio Garcez Leme, PhD

“…Design: Cross-sectional study using secondary data from a randomized clinical trial. …”
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Circadian rhythm dysfunction and psychopathology in the offspring of parents with bipolar disorder: a high-risk study in the Chinese population by Jing Wang, Tao Li, Yun Kwok Wing, Jihui Zhang, Jie Chen, Bin Zhang, Weidong Song, Chao Jiang, Jiyang Pan, Kun Zhang, Yaping Liu, Ngan Yin Chan, Hongliang Feng, Lulu Yang, Binbin Lei, Qunfeng Wang, Jessie Chi Ching Tsang, Joey W.Y. Chan, Kathleen Ries Merikangas

“…Background Understanding the evolution of circadian rhythm dysfunction and psychopathology in the high-risk population has important implications for the prevention of bipolar disorder. …”
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Development of a framework to structure decision-making in environmental and occupational health: A systematic review and Delphi study by Emily Senerth, Paul Whaley, Elie Akl, Brandy Beverly, Pablo Alonso-Coello, Ezza Jalil, Jayati Khattar, Nicole R. Palmer, Andrew Rooney, Holger J. Schünemann, Kristina A. Thayer, Katya Tsaioun, Rebecca L. Morgan

“…Conclusions: Findings of this mixed-methods study comprise a foundation for a GRADE EtD that is applicable for use in EOH decision-making, with implications for approaches to regulation of environmental and occupational exposures and the formulation of recommendations for interventions to prevent or mitigate undesirable health and other consequences.…”
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How can communities better prepare for future disasters? Learning from the tourism community resilience model from Bali, Indonesia by I Putu Gede Eka Praptika, Mohamad Yusuf, Jasper Hessel Heslinga

“…Practical implications – A tourism community resilience model based on local community responses has implications for the process of enriching academic research and community management practices in facing future crisis, particularly by involving local wisdom foundation. …”
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Ischemia-free liver transplantation improves long-term outcomes in a 5-year follow-up study by Zehua Jia, Jiaxing Zhu, Jiayi Zhang, Jian Zhang, Changjun Huang, Niancun Zhang, Songming Li, Yuqi Dong, Yao Liu, Ping Zeng, Tielong Wang, Zhitao Chen, Yunhua Tang, Qiang Zhao, Maogen Chen, Yinghua Chen, Anbin Hu, Weiqiang Ju, Yi Ma, Dongping Wang, Xiaofeng Zhu, Andrea Schlegel, Tullius G. Stefan, Xiaoshun He, Zhiyong Guo

“…Methods: We conducted a cohort study comparing long-term outcomes between IFLT and conventional liver transplantation (CLT) recipients of livers donated after brain death (DBD). …”
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Exploring voluntary sector specialist services for victim-survivors of sexual violence in England: the PROSPER co-production study by Caroline Bradbury-Jones, Sarah Damery, Kirsten Fruin, Clare Gunby, Jenny Harlock, Lucy Hebberts, Louise Isham, Anne-Marie Jones, Fay Maxted, Amelia Mighty, Priti Parmar, Laura Patterson, Jason Schaub, Fee Scott, Harriet Smailes, Debs Smith, Julie Taylor

“…We have presented transparent accounts of the strengths and limitations of this process. Core implications for policy, practice and education The study indicates the need for a sustainable funding framework for VSS services (e.g. a minimum 5-year funding period) with joined-up commissioning (and funding) from all statutory bodies whose services refer into specialist SV services. …”
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Industrial brand equity: a systematic literature review and directions for future research by Fernando Rey Castillo-Villar, Enrique Murillo

“…Also provided are managerial implications suggested by the findings of this research.…”
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Corporate social responsibility model based on Tri Hita Karana philosophy by Cok Istri Ratna Sari Dewi, Iwan Triyuwono, Bambang Hariadi

“…The theoretical and practical implications of this study are the encouragement for the uprising of CSR models that are more adaptive to the interests and the culture of local community.…”
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The Fracture Ankle Implant Review (FAIR) study: a national multicentre retrospective review of practice in implant choice, fixation methods, and outcomes in fixation of the fibula... by William G. Fishley, Thomas Baldock, Alan J. Hilley, Rory Morrison, Paul Baker, Dave Townshend, FAIR Study Collaborating Authors

“…A local pilot service evaluation previously identified variance in use of locking plates in all patterns with significant cost implications. The Fracture Ankle Implant Review (FAIR) study aimed to evaluate current practice and implant use across the UK, and review outcomes and complication rates between different fibula fixation methods. …”
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Decentralised internet governance: the case of a ‘peer-to-peer cloud’ by Francesca Musiani

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Investigation of Enterotoxigenic Coagulase-negative Staphylococci Isolated from Local and Imported Dairy Products; a Microbiological Study by Niyaz Sirwan Ali, Huner Hiwa Arif

“…Coagulase negative staphylococci (CNS) have been recorded as a conveying vector for virulence genes and have been implicated in some cases of food poisoning. Research interest in CNS has increased over the past decade following their implication in infections in animals and humans. …”
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Do sex hormones confound or mediate the effect of chronotype on breast and prostate cancer? A Mendelian randomization study. by Bryony L Hayes, Timothy Robinson, Siddhartha Kar, Katherine S Ruth, Konstantinos K Tsilidis, Timothy Frayling, Anna Murray, Richard M Martin, Deborah A Lawlor, Rebecca C Richmond

“…Sex hormones have been implicated in relation to chronotype and the development of both cancers. …”
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STRATEGI PEMASARAN DAN PENGEMBANGAN COMPETITIVE ADVANTAGE PADA NICHE FIRM : STUDI KASUS US.FROZEN FOOD by Tomi Gonga

“…The purpose of this study is to develop competitive advantage in US.frozen food and measuring the position of US.frozen food in the market through internal factor analysis and external factor analysis for implicating strategy that the benchmarked company applied according to the positon of US.frozen food. …”
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A bidirectional virtual teaching platform for postgraduate Point-of-Care Ultrasound training: a proof-of-concept study by Aanchal Ralhan, Queen Jacques, Alison MacDonald, Gillian Sheppard, Peter Rogers, Jordan Stone-McLean

“… Implication Statement Point-of-Care Ultrasound (POCUS) has become an important modality for procedural guidance and patient diagnostics. …”
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Tacrolimus Therapy Among Steroid-Resistant Nephrotic Syndrome Children: A Preliminary Study in West Java, Indonesia by Ahmedz Widiasta, Kurnia Wahyudi, Dedi Rachmadi

“…Objective: To explore the outcomes of Tac therapy for Steroid-Resistant Nephrotic Syndrome (SRNS) and its implication in reducing the number of CKD events. Methods: An open, prospective, cohort study was conducted at a tertiary hospital in Bandung, West Java, Indonesia. …”
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Improving reproducibility of differentially expressed genes in single-cell transcriptomic studies of neurodegenerative diseases through meta-analysis by Nathan Nakatsuka, Drew Adler, Longda Jiang, Austin Hartman, Evan Cheng, Eric Klann, Rahul Satija

“…Lastly, we evaluate factors influencing reproducibility of individual studies as a prospective guide for experimental design.…”
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