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Studies of the antitumor mechanism of action of dermaseptin B2, a multifunctional cationic antimicrobial peptide, reveal a partial implication of cell surface glycosaminoglycans.
Published 2017-01-01“…We previously reported that DRS-B2 possesses anticancer and antiangiogenic activities in vitro and in vivo. In the present study, we evaluated the antiproliferative activity of DRS-B2 on numerous tumor cell lines, its cell internalization and studies of its molecular partners as well as their influences on its structure. …”
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Immunological response and implications of Ad26.COV2. S (Janssen COVID-19 vaccine) vaccine in diabetic patients: a prospective cohort study in Ethiopia
Published 2025-05-01“…However, the immunological response of the patients with diabetes in Ethiopia has not been well studied.MethodsThis prospective cohort study assessed immune responses after vaccination with a single dose of the Ad26.COV2.S. …”
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Assessing the Clinical Relevance of Soluble PD-1 and PD-L1: A Multi-Cohort Study Across Diverse Tumor Types and Prognostic Implications
Published 2025-02-01“…<b>Background/Objectives:</b> Immune checkpoint inhibitors targeting the PD-1/PD-L1 pathway have revolutionized cancer immunotherapy, however the clinical relevance of their soluble forms (sPD-1 and sPD-L1) remains less studied. Soluble PD-1 and PD-L1 have been implicated in tumor progression, prognosis, and treatment response across various malignancies. …”
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Incidence, risk factors, and clinical implications of enfortumab vedotin-related cutaneous toxicity in urothelial carcinoma: a large-scale, real-world study in Japan
Published 2025-03-01“…However, EV-related cutaneous toxicity (EVRCT) remains a significant concern because of Nectin-4 expression in skin tissue. This study aimed to understand the incidence, risk factors, and clinical implications of EVRCT, focusing on relationships with treatment efficacy, using one of the largest real-world datasets from a Japanese la/mUC patient cohort. …”
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Rankings in Students’ decision-making process in Poland – implications for university management
Published 2020-09-01Get full text
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AN ASSESSMENT OF CIVIL-MILITARY RELATIONS AND ITS IMPLICATIONS ON NIGERIA'S NATIONAL SECURITY
Published 2022-05-01Get full text
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AN EXAMINATION OF RAWLS’ SOCIAL JUSTICE MODEL: AN ITS IMPLICATIONS FOR CONTEMPORARY NIGERIA
Published 2021-05-01Get full text
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Implications of locally managed SNSs on e-government implementation and community building
Published 2023-12-01“…This research aims to find the implications of the use of locally managed SNSs in each urban village in Surabaya. …”
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