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    Studies of the antitumor mechanism of action of dermaseptin B2, a multifunctional cationic antimicrobial peptide, reveal a partial implication of cell surface glycosaminoglycans. by Célia Dos Santos, Sabah Hamadat, Karen Le Saux, Clara Newton, Meriem Mazouni, Loussiné Zargarian, Mickael Miro-Padovani, Patricia Zadigue, Jean Delbé, Yamina Hamma-Kourbali, Mohamed Amiche

    Published 2017-01-01
    “…We previously reported that DRS-B2 possesses anticancer and antiangiogenic activities in vitro and in vivo. In the present study, we evaluated the antiproliferative activity of DRS-B2 on numerous tumor cell lines, its cell internalization and studies of its molecular partners as well as their influences on its structure. …”
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  7. 707

    Immunological response and implications of Ad26.COV2. S (Janssen COVID-19 vaccine) vaccine in diabetic patients: a prospective cohort study in Ethiopia by Chala Kenenisa Edae, Abdisa Tufa Bedada, Maria Degef Teklemariam, Abera Botore Gudisa, Abdurahman Adamu, Solomon Genet Gebre

    Published 2025-05-01
    “…However, the immunological response of the patients with diabetes in Ethiopia has not been well studied.MethodsThis prospective cohort study assessed immune responses after vaccination with a single dose of the Ad26.COV2.S. …”
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    Assessing the Clinical Relevance of Soluble PD-1 and PD-L1: A Multi-Cohort Study Across Diverse Tumor Types and Prognostic Implications by Nikolay E. Kushlinskii, Olga V. Kovaleva, Alexei N. Gratchev, Alexander A. Alferov, Yurii B. Kuzmin, Nikolai Y. Sokolov, Dmitry A. Tsekatunov, Irina B. Ryzhavskaya, Igor N. Kuznetsov, Dmitry N. Kushlinskii, Zaman Z. Mamedli, Ivan S. Stilidi

    Published 2025-02-01
    “…<b>Background/Objectives:</b> Immune checkpoint inhibitors targeting the PD-1/PD-L1 pathway have revolutionized cancer immunotherapy, however the clinical relevance of their soluble forms (sPD-1 and sPD-L1) remains less studied. Soluble PD-1 and PD-L1 have been implicated in tumor progression, prognosis, and treatment response across various malignancies. …”
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    Incidence, risk factors, and clinical implications of enfortumab vedotin-related cutaneous toxicity in urothelial carcinoma: a large-scale, real-world study in Japan by Y. Kita, T. Hara, T. Kawahara, K. Hashimoto, Y. Matsushita, H. Ito, T. Abe, A. Igarashi, S. Shimura, T. Sazuka, A. Yokomizo, N. Takaoka, M. Kato, T. Hazama, M. Miyake, Y. Sugino, J. Mutaguchi, A. Takahashi, Y. Shiraishi, S. Tatarano, Y. Takai, T. Mochizuki, S. Nakanishi, K. Mori, T. Yoshida, T. Hayashi, H. Otsuka, T. Anami, K. Okasho, K. Daizumoto, M. Kobayashi, I. Kobayashi, J. Watanabe, N. Nishiyama, T. Shibuya, Y. Matsui, H. Nishiyama, H. Kitamura, T. Kobayashi

    Published 2025-03-01
    “…However, EV-related cutaneous toxicity (EVRCT) remains a significant concern because of Nectin-4 expression in skin tissue. This study aimed to understand the incidence, risk factors, and clinical implications of EVRCT, focusing on relationships with treatment efficacy, using one of the largest real-world datasets from a Japanese la/mUC patient cohort. …”
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    Implications of locally managed SNSs on e-government implementation and community building by Inri Inggrit Indrayani

    Published 2023-12-01
    “…This research aims to find the implications of the use of locally managed SNSs in each urban village in Surabaya. …”
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