Peri-implant diseases triggered by oral microdysbiosis: pathogenesis and precision intervention strategies by Gang Chen, Xin Zhao, Xin Zhao, Bin Yang, Hongzheng Gu

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Insights into host-pathogen interaction based on the comparison of genomes of Leptospira interrogans isolated from dogs, humans, and a rodent in the same epidemiological context: A... by Lucas Nogueira Paz, Laise de Moraes, Luciane Amorim Santos, Camila Hamond, Melissa Hanzen Pinna

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The role of foliar endophytes in modulating southern corn rust severity: implications for biocontrol strategies by Lujia Yang, Lili Li, Yingying Song, Yongsheng Zhang, Jie Yang, Hongying Cui, Wenxiu Guo, Suhong Lv, Xingyuan Men

“…Current SCR management strategies prioritize genetic resistance and chemical control, but how foliar endophytic fungal communities modulate host susceptibility to P. polysora remains poorly understood. …”
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Transmission or Within-Host Dynamics Driving Pulses of Zoonotic Viruses in Reservoir-Host Populations. by Raina K Plowright, Alison J Peel, Daniel G Streicker, Amy T Gilbert, Hamish McCallum, James Wood, Michelle L Baker, Olivier Restif

“…Progress in combatting zoonoses that emerge from wildlife is often constrained by limited knowledge of the biology of pathogens within reservoir hosts. We focus on the host-pathogen dynamics of four emerging viruses associated with bats: Hendra, Nipah, Ebola, and Marburg viruses. …”
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Climate change and plant protection: challenges and innovations in disease forecasting systems in developing countries by Agatha Amnaay Aloyce

“…This proactive approach assesses the likelihood of disease outbreaks and increases in disease intensity, enabling timely intervention and resource optimization. However, climate change exacerbates this challenge by altering pathogen evolution and host-pathogen interactions, fostering the emergence of new pathogenic strains, shifting pathogen ranges, and expanding the geographic spread of plant diseases. …”
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Goblet cell breakdown: transcriptomics reveals Acinetobacter baumannii early and robust inflammatory response in differentiated human bronchial epithelial cells by Daniela Scribano, Claudia Tito, Astri D. Tagueha, Martina Pasqua, Luciana De Angelis, Francesco Fazi, Dolores Limongi, Marta De Angelis, Lucia Nencioni, Anna Teresa Palamara, Cecilia Ambrosi

“…However, in the last years, pneumonia caused by the opportunistic pathogen Acinetobacter baumannii have become difficult to treat due to the increase of the number of extensively drug resistant strains. …”
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Unveiling the complex extra‐oral colonization pathways and pathogenic mechanisms of Fusobacterium nucleatum, a heterogeneous oral pathogen by Zhiwei Guan, Houbao Qi, Qiang Feng

“…Next, we explore F. nucleatum’s ability to adhere to and invade host cells, which serves as a critical prerequisite for its pathogenicity. …”
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Modulation of host ATP levels by secreted bacterial effectors by Chunlin He, Chuang Li, Yao Liu, Tao-Tao Chen, Chunxiuli Li, Xiao Chu, Shuxin Liu, Lidong Wang, Yong Zhang, Songying Ouyang, Jiaqi Fu, Lei Song, Zhao-Qing Luo

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SARS-CoV-2 Replication Revisited: Molecular Insights and Current and Emerging Antiviral Strategies by Bryan John J. Subong, Imelda L. Forteza

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Essential role of hepcidin in host resistance to disseminated candidiasis by Tanmay Arekar, Divya Katikaneni, Sadat Kasem, Dhruv Desai, Thrisha Acharya, Augustina Cole, Nazli Khodayari, Sophie Vaulont, Bernhard Hube, Elizabeta Nemeth, Alexander Drakesmith, Michail S. Lionakis, Borna Mehrad, Yogesh Scindia

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Insights from genomics into bacterial pathogen populations. by Daniel J Wilson

“…However, population-level whole genome sequencing offers new hope in the fight against pathogenic bacteria. By providing insights into bacterial evolution and disease etiology, these approaches pave the way for novel interventions and therapeutic targets. …”
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Pathogenicity of commensal gut biofilm in prefrail aging by Guillaume Le Cosquer, Melissa Pannier, Elodie Meunier, Julie Thevenin, Elise Pyhourquet, Sophie Guyonnet, Bruno Vellas, Yohan Santin, Bruno Guiard, Angelo Parini, Louis Buscail, Barbara Bournet, Damien Guillemet, Celine Deraison, Nathalie Vergnolle, Jean-Paul Motta, for the IHU HealthAge INSPIRE/Open Science study group

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Spatio-temporal dynamics and risk cluster analysis of highly pathogenic avian influenza (H5N1) in poultry: Advancing outbreak management through customized regional strategies in E... by Yumna Elsobky, Mahmoud Eltholth, Ehsan Abdalla, Nourhan Eissa, Ghada Hadad, Mohamed Nayel, Akram Salama, Walid Mousa, Ahmed Kamal, Ashraf M. Abu-Seida, Osama K. Gaidan, Mohamed Elkamshishi

“…Background: Highly Pathogenic Avian Influenza HPAI (H5N1) has been endemic in Egypt for almost two decades, profoundly impacting both the poultry industry and public health. …”
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A case of Flavobacterium lindanitolerans meningitis and bacteraemia in an immunocompetent host by Amelia Benjamin, Robert Gray, Madhuri Vidwans

“…It has previously been described as an opportunistic pathogen in immunocompromised hosts. Here we described a case of meningitis and bacteraemia, in an immunocompetent individual who had undergone recent neurosurgical intervention.…”
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Host RhoA Signaling Controls Filamentous vs. Spherical Morphogenesis and Cell-to-Cell Spread of RSV via Lipid Raft Localization: Host-Directed Antiviral Target by Manoj K. Pastey, Lewis H. McCurdy, Barney S. Graham

“…These findings highlight a novel role for host RhoA signaling in regulating viral assembly through raft microdomain organization, offering a potential target for host-directed antiviral intervention aimed at altering RSV structural phenotypes and limiting pathogenesis.…”
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The role of glutathione for oxidative stress and pathogenicity of Streptococcus suis by Wei Peng, Qinggen Jiang, Yuting Wu, Li He, Bei Li, Weicheng Bei, Xia Yang

“…Streptococcus suis is an important zoonotic pathogen that threatens human and pig health. During infection, the host can impose oxidative stress to resist pathogen invasion. …”
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Host genetics and Chlamydia disease: prediction and validation of disease severity mechanisms. by Isao Miyairi, Jesse Ziebarth, Jonathan D Laxton, Xiaofei Wang, Nico van Rooijen, Robert W Williams, Lu Lu, Gerald I Byrne, Yan Cui

“…We infected a large panel of BXD strains with C. psittaci and assessed host genotype, IRG protein polymorphisms, pathogen load, expression of 32 cytokines, inflammatory cell populations, and weight change. …”
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Extracellular vesicles: the “Trojan Horse” within breast cancer host microenvironments by Yue Kang, Ling’ao Meng, Shi Bai, Shenglong Li

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Epidemics In The 21st Century: A Multifaceted Challenge by Shawana Sharif

“…The canvas of epidemics in the 21st century encompasses a spectrum of formidable adversaries. Changes in host population ecology, genetic mutations in pathogen reservoirs, the lack of disease control, the growing population, overcrowded urban areas, climate change, and globalization have resulted in the development of several epidemics and pandemics. …”
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Revisiting Pathogen Exploitation of Clathrin-Independent Endocytosis: Mechanisms and Implications by Oliver Goldmann, Eva Medina

“…Understanding how pathogens manipulate CIE in host cells can inform the development of novel antimicrobial and immunomodulatory interventions, offering new avenues for disease prevention and treatment.…”
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