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Human cell adaptation of the swine acute diarrhea syndrome coronavirus spike protein
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Species-specific circular RNA circDS-1 enhances adaptive evolution in Talaromyces marneffei through regulation of dimorphic transition.
Published 2025-03-01“…Thermal adaptability is a crucial characteristic for mammalian pathogenic fungi that originally inhabit natural ecosystems. …”
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564
The dual nature of plant growth-promoting bacteria: Benefits, risks, and pathways to sustainable deployment
Published 2025-01-01“…At the soil level, risks encompass disrupted microbial diversity, altered nutrient cycling, and horizontal gene transfer that may foster pathogenicity. These outcomes are driven by environmental factors (soil pH and moisture), host-specific interactions, and application practices. …”
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565
Pest Status of Subfamily Lymantriinae (Lepidoptera: Erebidae: Noctuoidea): Review
Published 2024-04-01“…Mango fruit rot caused by insects and microbes has become a significant threat to mango production in Southeast Asia and worldwide. Insect plant pathogens affect crop yields' profitability, quality, and quantity. …”
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Molecular Mechanisms of Potato Plant–Virus–Vector Interactions
Published 2025-07-01“…The review offers an integrated perspective essential for developing sustainable and precise control strategies against potato viral pathogens under changing climatic conditions.…”
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The Hsf1-sHsp cascade has pan-antiviral activity in mosquito cells
Published 2025-01-01“…Blocking virus replication in mosquitoes is a promising approach to prevent arbovirus transmission, the development of which requires in-depth knowledge of virus-host interactions and mosquito immunity. By integrating multi-omics data, we find that heat shock factor 1 (Hsf1) regulates eight small heat shock protein (sHsp) genes within one topologically associated domain in the genome of the Aedes aegypti mosquito. …”
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570
Oncolytic Vesicular Stomatitis Virus: Optimisation Strategies for Anti-Cancer Therapies
Published 2024-10-01“…Vesicular stomatitis virus (VSV) offers a promising platform due to its low prevalence and pathogenicity in humans, lack of pre-existing immunity, easily manipulated genome, rapid growth to high titers in a broad range of cell lines, and inability to integrate into the host genome. …”
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571
Role of the microbiome in regulation of the immune system
Published 2025-04-01“…These in turn protect against aberrant inflammatory or hyper-reactive processes and promote effector immune responses that quickly eliminate pathogens, such as SARS-CoV-2. Potent tolerance mechanisms should ensure that these immune cells do not over-react to non-pathogenic factors (e.g. food proteins), while maintaining the ability to respond to infectious challenges in a robust, effective and well controlled manner. …”
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572
Changes in metabolite profiles in the cerebrospinal fluid and in human neuronal cells upon tick-borne encephalitis virus infection
Published 2025-06-01“…Our aim was to investigate the host immune and metabolic responses associated with specific TBEV infectious outcomes. …”
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573
Epidemiology and economics of foot-and-mouth disease: current understanding and knowledge gaps
Published 2025-07-01“…Abstract Foot-and-mouth disease virus (FMDV) is one of the few veterinary pathogens that defines policy and global trade in animal products. …”
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574
The Hidden Threat: Rodent-Borne Viruses and Their Impact on Public Health
Published 2025-06-01“…They are major reservoirs of zoonotic pathogens, including viruses, bacteria, protozoa, and fungi, and are particularly effective at transmitting diseases, especially synanthropic species that live in close proximity to humans. …”
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Anabolic Properties of High Mobility Group Box Protein-1 in Human Periodontal Ligament Cells In Vitro
Published 2014-01-01“…High mobility group box protein-1 (HMGB1) is mainly recognized as a chemoattractant for macrophages in the initial phase of host response to pathogenic stimuli. However, recent findings provide evidence for anabolic properties in terms of enhanced proliferation, migration, and support of wound healing capacity of mesenchymal cells suggesting a dual role of the cytokine in the regulation of immune response and subsequent regenerative processes. …”
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576
Clostridium butyricum: a promising approach to enhancing intestinal health in poultry
Published 2025-05-01“…Second, C. butyricum enhances the integrity of the intestinal barrier. It enhances the integrity of epithelial tight junctions, reducing the permeability of the intestinal mucosa and preventing the invasion of pathogenic substances. …”
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577
Catalogue of fungi in China 6: Rhytismataceae on twigs of Rhododendron
Published 2025-02-01“…Members of the Rhytismataceae (Rhytismatales) are found all over the world, which include saprobes, endophytes, and plant pathogens. They can infect a wide variety of host plants and cause plant diseases. …”
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578
Insects Induced Mango Fruit Rot: Unraveling the Culprits
Published 2024-04-01“…Mango fruit rot caused by insects and microbes has become a significant threat to mango production in Southeast Asia and worldwide. Insect plant pathogens affect crop yields' profitability, quality, and quantity. …”
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Tick-borne flavivirus exoribonuclease-resistant RNAs contain a double loop structure
Published 2025-05-01“…Abstract Viruses from the Flaviviridae family contain human relevant pathogens that generate subgenomic noncoding RNAs during infection using structured exoribonuclease resistant RNAs (xrRNAs). …”
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Rift Valley Fever in Rwanda Is Urging for Enhancing Global Health Security Through Multisectoral One Health Strategy
Published 2025-01-01“…We recommend exploring cost-effective human and/or animal vaccination mechanisms for RVF, integrating AI-powered drones into dis-ease vectors surveillance and control, and the routine implementation of genomics-enhanced xenosurveillance to monitor changes in pathogens and vectors dynamics in order to inform poli-cymaking and guide the control interventions.…”
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