Human T-Lymphotropic Virus (HTLV): Epidemiology, Genetic, Pathogenesis, and Future Challenges by Francesco Branda, Chiara Romano, Grazia Pavia, Viola Bilotta, Chiara Locci, Ilenia Azzena, Ilaria Deplano, Noemi Pascale, Maria Perra, Marta Giovanetti, Alessandra Ciccozzi, Andrea De Vito, Angela Quirino, Nadia Marascio, Giovanni Matera, Giordano Madeddu, Marco Casu, Daria Sanna, Giancarlo Ceccarelli, Massimo Ciccozzi, Fabio Scarpa

“…Integration of proviral DNA into transcriptionally active regions of the host genome may contribute to oncogenesis and long-term viral latency. …”
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Targeting Ocular Biofilms with Plant-Derived Antimicrobials in the Era of Antibiotic Resistance by Monika Dzięgielewska, Michał Tomczyk, Adrian Wiater, Aleksandra Woytoń, Adam Junka

“…Their intrinsic resistance to antibiotics and evasion of host immune defenses significantly complicate treatments for ocular infections such as conjunctivitis, keratitis, blepharitis, and endophthalmitis. …”
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Morphometric and richness analysis of free-living and parasite taxa-invading street wetlands in Port Said, Egypt by Hadeer Abd El-hak Rashed, Layla Omran Elmajdoub, Eman Fayad, Ali Hussein Abu Almaaty

“…Future studies should prioritize broader geographic sampling, the integration of molecular techniques, and the exploration of host-parasite relationships. …”
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Microbiome-driven gene dysregulation in oesophageal cancer: a multi-omics analysis by Chaitali Nath

“…Studies have identified microbial shifts in oesophageal adenocarcinoma, particularly involving species such as Fusobacterium nucleatum, Campylobacter spp. and Porphyromonas gingivalis, which may contribute to carcinogenesis through immune modulation and epithelial remodeling.4,5 This study integrated host transcriptomics (GSE234304)6 and microbial circulating cell-free (cf)RNA profiling (GSE174302)7 to uncover microbiome-driven gene dysregulation in oesophageal cancer and explored its implications for early detection and therapeutic targeting. …”
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BLIS Fingerprinting as a Tool to Investigate the Distribution and Significance of Bacteriocin Production and Immunity in <i>Streptococcus pyogenes</i> and <i>Streptococcus salivari... by John R. Tagg, John D. F. Hale, Liam K. Harold

“…In <i>S. pyogenes</i>, lantibiotic production has been implicated in virulence modulation, raising important questions about its role in pathogenicity and host immune evasion. Conversely, <i>S. salivarius</i>, a prominent commensal and probiotic candidate species, utilizes its lantibiotic arsenal to confer colonization benefits and mediate beneficial interactions, especially within the oral and upper respiratory tract microbiomes. …”
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An aphid-transmitted polerovirus is mutualistic with its insect vector by accelerating population growth in both winged and wingless individuals by Yingjie Liu, Pengjun Xu, Huijie Dai, Fei Wang, Hao Zong, Hailin Yang, Lifang Wang, Robert I. Graham, Xiufang Wang, Yonghui Zhang, Guangwei Ren, Yonghao Dong

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eDNA‐Based Detection of Invasive Crayfish and Crayfish Plague in Estonia by Michael Oliewo Aluma, Katrin Kaldre, David A. Strand, Margo Hurt, Lilian Pukk

“…Detection of P. virginalis was only observed in samples with amplifications below the limit of detection, and A. astaci eDNA was found in only one water body hosting invasive crayfish species. Although we could not establish a convincing quantitative correlation between the estimated P. leniusculus eDNA concentration and crayfish population density, we conclude that the eDNA approach is promising and, with further optimization, it can be integrated into routine monitoring of crayfish and crayfish plague pathogen as a supplement to traditional trapping methods.…”
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Roles of arbuscular mycorrhizal fungi in plant growth and disease management for sustainable agriculture by Muhammad Umer, Naureen Anwar, Mustansar Mubeen, Yun Li, Amjad Ali, Mohammed O. Alshaharni, Pingwu Liu

“…Genomic and transcriptomic studies have elucidated key components of the common symbiosis-signaling pathway, supporting AMF-host specificity and functional outcomes. AMF is a promising biotechnological tool for integrated pest, disease, and nutrient management. …”
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High Schistosoma mansoni infection intensity is associated with distinct gut microbiota and low levels of systemic cytokines in children along the Albert-Nile, Northern Uganda by Julius Mulindwa, Ibra Lujumba, Caroline Musiime, Joyce Namulondo, Magambo Phillip Kimuda, Oscar Nyangiri, Gloria Cuu, Caroline Mwubaha, Stephen Tukwasibwe, Aloysious Ssemaganda, Isaac Ssewanyana, Barbara Nerima, Rhona Baingana, Harry Noyes, Annette MacLeod, Enock Matovu

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CTLA-4 expressing innate lymphoid cells modulate mucosal homeostasis in a microbiota dependent manner by Jonathan W. Lo, Jan-Hendrik Schroeder, Luke B. Roberts, Rami Mohamed, Domenico Cozzetto, Gordon Beattie, Omer S. Omer, Ellen M. Ross, Frank Heuts, Geraldine M. Jowett, Emily Read, Matthew Madgwick, Joana F. Neves, Tamas Korcsmaros, Richard G. Jenner, Lucy S. K. Walker, Nick Powell, Graham M. Lord

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Distinct cervical microbiome and metabolite profiles before and after menopause: implications for cervical cancer progression by Rie Kawasaki, Rie Kawasaki, Iwao Kukimoto, Eiji Nishio, Sayaka Otani, Haruki Nishizawa, Yasuhiro Maeda, Aya Iwata, Aya Iwata, Takuma Fujii, Takuma Fujii, Takuma Fujii

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Synergistic impact of Salmonella typhimurium and Eimeria spp. coinfection on turkey poults: Growth performance, salmonella colonization, and ceca microbiota insights by Hamid Reza Rafieian-Naeini, Hanseo Ko, Doyun Goo, Venkata Sesha Reddy Choppa, Seshidhar Reddy Gudidoddi, Hemanth Reddy Katha, Woo Kyun Kim

“…On the other side, coccidiosis is induced by Eimeria (E.) species. involves the destruction of host intestinal epithelial cells and subsequent invasion of pathogens, resulting in performance reduction and enhanced pathogen infection in poultry and economic losses for the poultry industry. …”
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Gut microbiota influence on lung cancer risk through blood metabolite mediation: from a comprehensive Mendelian randomization analysis and genetic analysis by Yizhao Du, Qin Wang, Zongmei Zheng, Hailun Zhou, Yang Han, Ao Qi, Lijing Jiao, Lijing Jiao, Yabin Gong

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Genetic and codon usage analyses reveal the evolution of the seoul virus by Yamei Wei, Yamei Wei, Yanan Cai, Yanan Cai, Xu Han, Zhanying Han, Yanbo Zhang, Yonggang Xu, Caixiao Jiang, Qi Li, Qi Li

“…The S segment demonstrated the strongest pathogenicity due to its closer codon usage alignment with Homo sapiens (H. sapiens) and Rattus norvegicus (R. norvegicus), whereas the L segment showed the lowest host adaptation. …”
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Multifunctional hydrogel with mild photothermal properties enhances diabetic wound repair by targeting MRSA energy metabolism by Qian Gao, Fangfang Hu, Zihan Chai, Caiyun Zheng, Wenhui Zhang, Ke Pu, Ziyi Yang, Yanni Zhang, Seeram Ramrkrishna, Xianglong Wu, Tingli Lu

“…Abstract Background Diabetic wound infections, exacerbated by multidrug-resistant pathogens like MRSA, remain a critical challenge due to biofilm persistence and dysregulated oxidative-inflammatory-metabolic crosstalk. …”
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Reverse vaccinology and immunoinformatics approaches for multi-epitope vaccine design against Klebsiella pneumoniae reveal a novel vaccine target protein by Mayada M. Elfadil, Samah Omer A. Samhoon, Moaaz M. Saadaldin, Sabah A.E. Ibrahim, Ahmed Abdelghyoum M. Mohamed, Omnia H. Suliman, Osama Mohamed, Nadzirah Damiri, Mohd Firdaus-Raih, Sofia B. Mohamed, Qurashi. M. Ali

“…Klebsiella pneumoniae (K. pneumoniae), a Gram-negative pathogen, is a leading cause of hospital-acquired infections in Sudan and worldwide. …”
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The relationship between the skin microecology and the skin barrier by LIN Tianyi, CHEN Jiaoquan, OU Shanshan, WU Weihong, ZOU Hui, CHEN Ziyan, PENG Liqian, CHEN Quan, LI Huaping, ZHU Huilan

“…These microbial inhabitants contribute greatly to the homeostasis of the skin microenvironment by communicating with the host cells and maintaining the structural integrity and function of the skin barrier. …”
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Saccharin disrupts bacterial cell envelope stability and interferes with DNA replication dynamics by Rubén de Dios, Kavita Gadar, Chris R Proctor, Evgenia Maslova, Jie Han, Mohamed A N Soliman, Dominika Krawiel, Emma L Dunbar, Bhupender Singh, Stelinda Peros, Tom Killelea, Anna-Luisa Warnke, Marius M Haugland, Edward L Bolt, Christian S Lentz, Christian J Rudolph, Ronan R McCarthy

“…In addition, we test its potential to disrupt established biofilms (single-species as well as polymicrobial) and its capacity to re-sensitise multidrug-resistant pathogens to last-resort antibiotics. Finally, we present in vitro and ex vivo evidence of the versatility of saccharin as a potential antimicrobial by integrating it into an effective hydrogel wound dressing.…”
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Development of Enzyme-Mediated Duplex Exponential Amplification Assay for Detection and Identification of <i>Meloidogyne enterolobii</i> in Field by Bingxue Sun, Bo Gao, Rongyan Wang, Shulong Chen, Xiuhua Li, Yonghao Dong, Juan Ma

“…The root-knot nematode <i>Meloidogyne enterolobii</i> has emerged as a devastating pathogen in global agricultural systems. Its geographic distribution is progressively expanding from tropical to temperate zones, leading to difficulties in discerning the symptoms it causes from those of congeners such as <i>M. incognita</i>. …”
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Microbiological mechanisms of oral mucosal disease: oral-intestinal crosstalk and probiotic therapy by Qi Zhou, Panpan Liu, Muni Chen, Hao He, Mengting Xu, Qianrong Xu, Jianfeng Yu, Yutian Deng, Jiayu Yan, Jiayu Yan, Jiayu Yan, Yueqiang Wen

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