Achieving healthy aging through gut microbiota-directed dietary intervention: Focusing on microbial biomarkers and host mechanisms by Yue Xiao, Yingxuan Feng, Jianxin Zhao, Wei Chen, Wenwei Lu

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Precision microbial regulation: Strategies for modulating GIT microbiota for host health by Pei Zhong, Qin Li, Yanmei Zhang, Cheng Guo, Mahmoud M. Abdelsattar, Yanliang Bi

“…Finally, we highlight support methods for optimizing modulation strategies, including the timing of microbial regulation, the selection of microbial targets, and the importance of monitoring the gastrointestinal environment to guide effective microbial interventions.…”
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Host‐Microbial Cometabolite Ursodeoxycholic Acid Protects Against Poststroke Cognitive Impairment by Xuxuan Gao, Feng Zhang, Jiafeng Zhang, Yu Ma, Yiting Deng, Jiaying Chen, Yueran Ren, Huidi Wang, Boxin Zhao, Yan He, Jia Yin

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Co-occurring microbial guilds in pig fecal microbiota: key drivers and effects on host performance by Ioanna-Theoni Vourlaki, Raquel Rio-Lopez, Adrià Clavell-Sansalvador, Lino C. Ramírez-Ayala, Maria Ballester, Juan P. Sanchez, Miriam Piles, Raquel Quintanilla, Angela C. da Fonseca de Oliveira, Leandro Batista Costa, Antoni Dalmau, Yuliaxis Ramayo-Caldas

“…Moreover, while the ES concept has proven valuable in dissecting microbial communities into assemblies of underlying microbial guilds, our results emphasize the relevance of customizing microbial interventions strategies based on the nutritional and health requirements at each stage of the porcine production cycle.…”
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Unraveling microbial pathogenesis through omics technologies for better therapeutic interventions by Ankita Sharma, Alka Rana, Binoy Kumar, Poonam Kumari, Kanika Choudhary, Sunil Kumar, Dixit Sharma

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Comparative analysis of goat and bovine milk proteins in the improvement of sarcopenia based on host-microbial interactions by Ruoyu Wang, Yuxin Ma, Meng Sun, Lutong Li, Zhaofeng Zhang

“…Moreover, we found that whey protein and casein could modulate host-microbial arginine co-metabolism, which shows their potential as precision nutritional supplements for the management of sarcopenia. …”
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Probiotic modulation of symbiotic gut microbial–host metabolic interactions in a humanized microbiome mouse model by Francois‐Pierre J Martin, Yulan Wang, Norbert Sprenger, Ivan K S Yap, Torbjörn Lundstedt, Per Lek, Serge Rezzi, Ziad Ramadan, Peter van Bladeren, Laurent B Fay, Sunil Kochhar, John C Lindon, Elaine Holmes, Jeremy K Nicholson

“…Statistical analysis of the compartmental fluctuations in diverse metabolic compartments, including biofluids, tissue and cecal short‐chain fatty acids (SCFAs) in relation to microbial population modulation generated a novel top‐down systems biology view of the host response to probiotic intervention. …”
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Facilitating a high-quality dietary pattern induces shared microbial responses linking diet quality, blood pressure, and microbial sterol metabolism in caregiver-child dyads by Emily B. Hill, Li Chen, Michael T. Bailey, Amrik Singh Khalsa, Ross Maltz, Kelly Kelleher, Colleen K. Spees, Jiangjiang Zhu, Brett R. Loman

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Hypothesis: Ran GTPase-Based Potential Therapeutic Interventions Against Lethal Microbial Infections by Peter M.C. Wong

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Industrial diet intervention modulates the interplay between gut microbiota and host in semi-stray dogs by Soufien Rhimi, Amin Jablaoui, Juan Hernandez, Vincent Mariaule, Nizar Akermi, Tristan Méric, Héla Mkaouar, Magdalena Wysocka, Adam Lesner, Mohamed Ali Borgi, Emmanuelle Maguin, Moez Rhimi

“…Abstract Background The gut microbiota and derived metabolites play a key role in regulating host physiology. Diet is identified as a key regulatory factor of the microbiota composition and, potentially, of subsequent functionalities. …”
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Dual-species proteomics and targeted intervention of animal-pathogen interactions by Yang Sylvia Liu, Chengqian Zhang, Bee Luan Khoo, Piliang Hao, Song Lin Chua

“…Conclusion: Our work provides a novel SILAC-based proteomics method that can simultaneously evaluate host and microbe proteomes, with future applications in higher host organisms and other microbial species. …”
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Deep learning enabled integration of tumor microenvironment microbial profiles and host gene expressions for interpretable survival subtyping in diverse types of cancers by Haohong Zhang, Xinghao Xiong, Mingyue Cheng, Lei Ji, Kang Ning

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Immunogenic proteins of Orientia tsutsugamushi and implications for scrub typhus intervention: A narrative review by Shakshi Shah, Ankita Sharma, Alka Rana, Rakesh Kumar, Amit Kumar Sharma, Sunil Kumar, Dixit Sharma

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Exploring the hidden complexities of the colostrum and milk microbiome in livestock: emerging insights and challenges by Diana Luise, Silvia Carta, Paola Cremonesi, Rosanna Marino, Bianca Castiglioni

“…It examines the methods and protocols for sampling and sequencing the milk microbial community. In addition, the review discusses the potential origins of the milk microbial community as well as intrinsic and extrinsic factors like host genetics and feeding strategies that can drive changes in the milk microbial community of livestock. …”
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Implications of gut microbiota-mediated epigenetic modifications in intestinal diseases by Qihong Zhang, Yun Liu, Yuheng Li, Guangdong Bai, Jiaman Pang, Miaomiao Wu, Jiawei Li, Xuan Zhao, Yaoyao Xia

“…Importantly, mechanistic studies based on animal models or human cells have demonstrated that the gut microbiota, and other environmental factors, influence targeted gene expression and activate immune pathways through host epigenetic dysregulation, which are closely associated with the development of IBD and CRC. …”
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Pathways of host cell exit by intracellular pathogens by Antje Flieger, Freddy Frischknecht, Georg Häcker, Mathias W. Hornef, Gabriele Pradel

“…Key microbial molecules involved in host cell exit are highlighted and discussed as potential targets for future interventional approaches.…”
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Microbial metabolites and immune modulation by Hassan Ghasemi

“…Additionally, translational hurdles -such as ensuring the stability, bioavailability, and targeted delivery of microbial metabolites- must be overcome to realize their full clinical potential.14 Microbial metabolites are central to immune modulation, bridging the intricate relationship between host and microbiota. …”
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The role of foliar endophytes in modulating southern corn rust severity: implications for biocontrol strategies by Lujia Yang, Lili Li, Yingying Song, Yongsheng Zhang, Jie Yang, Hongying Cui, Wenxiu Guo, Suhong Lv, Xingyuan Men

“…Current SCR management strategies prioritize genetic resistance and chemical control, but how foliar endophytic fungal communities modulate host susceptibility to P. polysora remains poorly understood. …”
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Modulation of host ATP levels by secreted bacterial effectors by Chunlin He, Chuang Li, Yao Liu, Tao-Tao Chen, Chunxiuli Li, Xiao Chu, Shuxin Liu, Lidong Wang, Yong Zhang, Songying Ouyang, Jiaqi Fu, Lei Song, Zhao-Qing Luo

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Essential role of hepcidin in host resistance to disseminated candidiasis by Tanmay Arekar, Divya Katikaneni, Sadat Kasem, Dhruv Desai, Thrisha Acharya, Augustina Cole, Nazli Khodayari, Sophie Vaulont, Bernhard Hube, Elizabeta Nemeth, Alexander Drakesmith, Michail S. Lionakis, Borna Mehrad, Yogesh Scindia

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