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The SEPALLATA-like gene HrSEP1 in Hippophae rhamnoides regulates flower development by interacting with other MADS-box subfamily genes
Published 2025-01-01“…MADS-box genes are classified into five categories: ABCDE, including SEP1, SEP2, SEP3, SEP4, and other homologous genes, which play important roles in floral organ development. …”
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Postrecruitment Function of Yeast Med6 Protein during the Transcriptional Activation by Mediator Complex
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184
A Multiagent Alphavirus DNA Vaccine Delivered by Intramuscular Electroporation Elicits Robust and Durable Virus-Specific Immune Responses in Mice and Rabbits and Completely Protect...
Published 2018-01-01“…There remains a need for vaccines that can safely and effectively protect against the biological threat agents Venezuelan (VEEV), western (WEEV), and eastern (EEEV) equine encephalitis virus. …”
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185
A new strategy for the treatment of advanced ovarian cancer: utilizing nanotechnology to regulate the tumor microenvironment
Published 2025-02-01“…Despite the challenges posed by the TME in the treatment of AOC, the unique biological advantages of nanoparticles (NPs) make it possible to regulate the TME. …”
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186
New insights into the salt-responsive regulation in eelgrass at transcriptional and post-transcriptional levels
Published 2025-02-01“…By examining the transcriptional responses of homologous genes in eelgrass, rice, and maize, we identified several groups of genes that are conserved in their response to salt stress. …”
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187
Microsporidian Nosema bombycis secretes serine protease inhibitor to suppress host cell apoptosis via Caspase BmICE.
Published 2025-01-01“…Microsporidia are a group of intracellular pathogens that actively manipulate host cell biological processes to facilitate their intracellular niche. …”
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188
Based on network pharmacology and molecular docking to study the mechanisms of active ingredients of ginseng in the treatment of atopic dermatitis
Published 2025-01-01“…[Methods] The databases of OMIM, TTD, CTD, GEO and GeneCards were used to screen the homologous targets and disease targets of active ingredients in ginseng. …”
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Characterization of the genomic landscape in liver oligometastatic NSCLC
Published 2025-01-01“…The co-occurrence rate of TP53 and RB1 in our cohort was significantly higher than that in the TCGA-LUAD cohort. Age, APOBEC, homologous recombination deficiency (HRD) and deficient mismatch repair (dMMR) established the mutational signature of liver oligometastatic NSCLC. …”
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191
Prognostic Significance and Therapeutic Potential of SERPINE1 in Head and Neck Squamous Cell Carcinoma
Published 2025-01-01“…The connection between the biological function of the gene and prognosis was scrutinized through immune infiltration and enrichment analyses. …”
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192
Genetic and biochemical characterization of a radical SAM enzyme required for post-translational glutamine methylation of methyl-coenzyme M reductase
Published 2025-02-01“…Here, we show that two different MgmA homologs are able to methylate MCR in vivo when expressed in Methanosarcina acetivorans, an organism that does not normally possess this PTM. …”
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193
Marek's disease virus-1 unique gene LORF1 is involved in viral replication and MDV-1/Md5-induced atrophy of the bursa of Fabricius.
Published 2025-02-01“…MDV LORF1 is unique to serotype I MDV (MDV-1), lacking homologs in other herpesviruses, and has not been explored yet. …”
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194
Deregulated methylation and expression of PCDHGB7 in patients with non-small cell lung cancer: a novel prognostic and immunological biomarker
Published 2025-01-01“…Its function in lung cancer has not been elucidated.MethodsWe comprehensively investigated PCDHGB7 expression, prognosis, biological function, methylation patterns, and it’s relationship with immune infiltration and immunotherapy response through public datasets (HPA, TCGA, GEO, OncoDB and MEXPRESS). …”
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195
The immunogenicity of PRV ΔgE/TK/UL49.5 three-gene-deleted vaccine in mice
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196
Albino lethal 13, a chloroplast‐imported protein required for chloroplast development in rice
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The Effect of Blood-Derived Products on the Chondrogenic and Osteogenic Differentiation Potential of Adipose-Derived Mesenchymal Stem Cells Originated from Three Different Location...
Published 2019-01-01“…Both PRP types had a different biological effect depending upon concentration, whereas hyperacute serum seemed to have a more consistent effect, independent of the used concentration. …”
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An integrative analysis of ASCL1 in breast cancer and inhibition of ASCL1 increases paclitaxel sensitivity by activating ferroptosis via the CREB1/GPX4 axis
Published 2025-02-01“…However, the biological role of ASCL1 in BC still remains largely unexplored. …”
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