Molecular biological research and molecular homologous modeling of Bw.03 subgroup by WANG Li, KONG Yongkui, JIN Huifang, LIU Xin, XIE Ying, LIU Xue, CHANG Yanli, WANG Yafang, YANG Shumiao, ZHU Di, YANG Qiankun

Subjects: Get full text

The homologous recombination factors BRCA2 and PALB2 interplay with mismatch repair pathways to maintain centromere stability and cell viability by Emily Graham, Lucia Rampazzo, Chin Wei Brian Leung, Jacob Wall, Emőke Zsanett Gerőcz, Mikhail Liskovykh, Nikolay Goncharov, Xanita Saayman, Ramazan Gundogdu, Masato T. Kanemaki, Hiroshi Masumoto, Vladimir Larionov, Natalay Kouprina, Fumiko Esashi

Get full text

Identifying key genes in cancer networks using persistent homology by Rodrigo Henrique Ramos, Yago Augusto Bardelotte, Cynthia de Oliveira Lage Ferreira, Adenilso Simao

“…We integrate mutation data from six cancer types and three biological functions: DNA Repair, Chromatin Organization, and Programmed Cell Death. …”
Get full text

In silico methods for immunogenicity risk assessment and human homology screening for therapeutic antibodies by Aimee E. Mattei, Andres H. Gutierrez, Soorya Seshadri, Jacob Tivin, Matt Ardito, Amy S. Rosenberg, William D. Martin, Anne S. De Groot

Get full text

Competence induction of homologous recombination genes protects pneumococcal cells from genotoxic stress by David De Lemos, Anne-Lise Soulet, Violette Morales, Mathieu Berge, Patrice Polard, Calum Johnston

“…ABSTRACT Homologous recombination (HR) is a universally conserved mechanism of DNA strand exchange between homologous sequences, driven in bacteria by the RecA recombinase. …”
Get full text

PIPENN-EMB ensemble net and protein embeddings generalise protein interface prediction beyond homology by David P. G. Thomas, Carlos M. Garcia Fernandez, Reza Haydarlou, K. Anton Feenstra

“…Abstract Protein interactions are crucial for understanding biological functions and disease mechanisms, but predicting these remains a complex task in computational biology. …”
Get full text

Distinct roles of Constitutive Photomorphogenesis Protein 1 homolog (COP1) in human hepatocyte models by Sébastien Soubeyrand, Paulina Lau, Ruth McPherson, Ruth McPherson

“…IntroductionConstitutive Photomorphogenesis Protein 1 homolog (COP1) is a conserved E3 ligase with key roles in several biological systems. …”
Get full text

Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood–brain barrier by Joanna R. Thomas, William J. E. Frye, Robert W. Robey, Andrew C. Warner, Donna Butcher, Jennifer L. Matta, Tamara C. Morgan, Elijah F. Edmondson, Paula B. Salazar, Suresh V. Ambudkar, Michael M. Gottesman

Get full text

Defective homologous recombination and genomic instability predict increased responsiveness to carbon ion radiotherapy in pancreatic cancer by Brock J. Sishc, Janapriya Saha, Elizabeth M. Alves, Lianghao Ding, Huiming Lu, Shih-Ya Wang, Katy L. Swancutt, James H. Nicholson, Angelica Facoetti, Arnold Pompos, Mario Ciocca, Todd A. Aguilera, Michael D. Story, Anthony J. Davis

“…We utilized a panel of human PDAC cell lines with diverse genetic profiles to determine their sensitivity to CIRT compared to γ-rays, assessing relative biological effectiveness (RBE) at 10% survival, which ranged from 1.96 to 3.04. …”
Get full text

Correction: Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood–brain barrier by Joanna R. Thomas, William J. E. Frye, Robert W. Robey, Andrew C. Warner, Donna Butcher, Jennifer L. Matta, Tamara C. Morgan, Elijah F. Edmondson, Paula B. Salazar, Suresh V. Ambudkar, Michael M. Gottesman

Get full text

Production of all-triploid derived from gynogenetic homologous diploid crucian carp (♀) × diploid red crucian carp (♂) by Chongqing Wang, Yan Tang, Xiang Luo, Yuxin Zhang, Yue Zhou, Qingwen Xiao, Zhengkun Liu, Xinyi Deng, Xu Huang, Xidan Xu, Xiaowei Xu, Kun Zhang, Qinbo Qin, Shaojun Liu

Get full text

Inhibition of GSK3β is synthetic lethal with FHIT loss in lung cancer by blocking homologous recombination repair by Shishi Tao, Yue Pu, Eun Ju Yang, Guowen Ren, Changxiang Shi, Li-Jie Chen, Liang Chen, Joong Sup Shim

Get full text

Using In Silico Methods to Identify Protein Tyrosine Kinase A (PtkA) Homolog in Non-Tuberculous Mycobacteria (NTM) by Swati Jaiswal, Sanjay Kumar

Get full text

Polymorphisms of Homologous Recombination RAD51, RAD51B, XRCC2, and XRCC3 Genes and the Risk of Prostate Cancer by Maria Nowacka-Zawisza, Ewelina Wiśnik, Andrzej Wasilewski, Milena Skowrońska, Ewa Forma, Magdalena Bryś, Waldemar Różański, Wanda M. Krajewska

Get full text

Evolutionary conserved regulation of TFEB stability by the E3 ubiquitin ligase WWP2 modulates response to stress in vivo by Juan A. Garcia-Sanchez, Estelle Bonnet, Céline Loubatier, Anne Doye, Guillaume Paillier, Fabien Segui, Frédéric Larbret, Paul Chaintreuil, Ludovic Batistic, Cédric Torre, Marcel Deckert, Jolanta Polanowska, Patrick Munro, Laurent Boyer, Orane Visvikis

Get full text

De novo assembly of the mitochondrial genome of Glycyrrhiza glabra and identification of two types of homologous recombination configurations caused by repeat sequences by Guowang Zhou, Meiling Qin, Xiuli Liu, Yonghui Qi, Xiaobin Ou, Min Tang

“…We identified 79 out of the 388 DSRs as potentially involved in homologous recombination. We identified five forward repeats and four palindromic repeats that facilitate homologous recombination and induce alterations in the mitochondrial genome structure. …”
Get full text

Evolutionary and functional divergence of Sfx, a plasmid-encoded H-NS homolog, underlies the regulation of IncX plasmid conjugation by Avril Wang, Martha Cordova, William Wiley Navarre

“…Recent bioinformatic analyses have revealed that plasmid-encoded H-NS homologs are widespread and exhibit high sequence diversity. …”
Get full text

Molecular Characterization of Legionellosis Drug Target Candidate Enzyme Phosphoglucosamine Mutase from (strain Paris): An Approach by Anayet Hasan, Habibul Hasan Mazumder, Arif Khan, Mohammad Uzzal Hossain, Homaun Kabir Chowdhury

Get full text

Homology Modeling and Expression of Recombinant NS5-RdRp Based on the Indonesian Local Strain of Dengue Virus for Anti-Dengue Drug Development by Toto Subroto, Ade Rizqi Ridwan Firdaus, Shinta Kusumawardani, Taufik Ramdani Tohari, Theresia Adventina Nababan, Wulan Pertiwi, Muhammad Fadhlillah, Sri Agung Fitri Kusuma, Yaya Rukayadi

Get full text

In silico evaluation of missense SNPs in cancer-associated Cystatin A protein and their potential to disrupt Cathepsin B interaction by Shafaat Hossain, Omar Hamza Bin Manjur, Mst Sharmin Sultana Shimu, Tamanna Sultana, Mustafizur Rahman Naim, Shahariar Siddique, Abdullah Al Mamun, Md Miftaur Rahman, Md Abu Saleh, Md Rakibul Hasan, Tania Rahman

Get full text