Interferon (IFN)-gamma (γ) inducible protein 10 (IP-10) in the diagnosis of latent and active tuberculosis in Bacille Calmette Guerin (BCG)-vaccinated pediatric population. by Magdalena Druszczynska, Michał Seweryn, Sebastian Wawrocki, Anna Pankowska, Anastasiia Kulbachko, Magdalena Jurczak, Magdalena Kowalewska-Pietrzak

“…Furthermore, detecting cases of latent Mycobacterium tuberculosis (M.tb) infection (LTBI) that have a high risk of progressing to active TB disease remains a significant diagnostic hurdle.…”
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Pancreatic Cancer: Molecular, Biochemical, Chemopreventive, and Therapeutic Aspects by Juan Iovanna, José Luis Neira

“…The presence of occult or clinical metastases at the time of diagnosis, together with the lack of effective chemotherapies, contributes to the high mortality in patients with PC. Its lethal nature stems from its propensity to disseminate rapidly to the lymphatic system and distant organs. …”
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Effects of Bioactive Packaging Films Incorporated with Bifidocin A on Microbial Reduction and Quality Parameters of Chill-Stored Spanish Mackerel (Scomberomorus niphonius) Fillets by Guorong Liu, Xue Li, Xu Hao, Chengtao Wang, Baoguo Sun

“…Hence, the bioactive packaging films incorporated with bifidocin A could be a promising hurdle technology and alternative to conventional processes used for improving the safety and quality of chilled mackerel fillets.…”
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Reductions in Muscle Strength and Range of Motion Cause Locomotion Disability via Locomotion-Related Functional Limitation in Japanese Older Adults: A Cross-Sectional Study by Hungu Jung, Shigeharu Tanaka, Yuji Iwamoto, Takashi Kawano, Masahiro Yamasaki, Ryo Tanaka

“…To measure locomotion-related functional limitations, participants underwent a 10 m hurdle walking test and side-step test. Thereafter, path analysis was conducted for testing the hypothetical model. …”
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An exploration of desired abstinent and non-abstinent recovery outcomes among people who use methamphetamine by Alex Elswick, Amanda Fallin-Bennett, Karen L. Roper, Evan Batty, Christopher J. McLouth, William Stoops, Hilary L. Surratt, Carrie B. Oser

“…Conclusion Our findings indicate the importance of non-abstinent recovery outcomes among PWUM, suggesting high acceptability of non-abstinent recovery targets by people with lived experience. …”
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Intracalvariosseous injection: an approach for central nervous system drug delivery through skull bone marrow with a preclinical research in strokeResearch in context by Wenqian Liu, Mo Yang, Nanxing Wang, Xiangrong Liu, Chaoyu Wang, Kaibin Shi, Fu-Dong Shi, Yuesong Pan, Mingjun Zhang, Zhiwei Sun, Yongjun Wang, Yilong Wang

“…Summary: Background: Central nervous system (CNS) accessibility constitutes a major hurdle for drug development to treat neurological diseases. …”
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Applying the Aajiiqatigiingniq Research Methodology: approaches and lessons learned through collaborative survey development and analysis by Natalie Ann Carter, Shirley Tagalik, Gita Ljubicic

“…In this process, we have come to recognize our strength in connection, Local Research Coordinators as Highly Qualified Personnel, the four Rs of collaborative analysis, and the challenges of hurdling institutions. …”
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Neonatal Intensive Care Unit Apocalypse—Rise of the World Health Organization Priority Pathogens by Apurva Kawdiya, Swati Bhalse, Gaurav Mogra, Kewal K Arora

“…Background: With higher neonatal survival, increasing neonatal intensive care unit (NICU) admissions, and rampant use of antibiotics, highly resistant organisms have become a major hurdle in the path of intact survival of neonates. …”
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