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  1. 3381
  2. 3382

    Protein kinase 2 of the giant sarcomeric protein UNC-89 regulates mitochondrial morphology and function by Yohei Matsunaga, Hiroshi Qadota, Nasab Ghazal, Leila Lesanpezeshki, Till Dorendorf, Jasmine C. Moody, Arnaud Ahier, Courtney J. Matheny, Siva A. Vanapalli, Steven Zuryn, Olga Mayans, Jennifer Q. Kwong, Guy M. Benian

    Published 2024-10-01
    “…C. elegans expressing UNC-89 with a lysine to alanine (KtoA) mutation to inactivate PK2 have normally organized sarcomeres and SR, and normal muscle function. …”
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  3. 3383

    Exploring the genomic landscape of the GP63 family in Trypanosoma cruzi: Evolutionary dynamics and functional peculiarities. by Luisa Berná, María Laura Chiribao, Sebastián Pita, Fernando Alvarez-Valin, Adriana Parodi-Talice

    Published 2025-03-01
    “…This suggests that these proteins may have evolved under species-specific selective (functional) pressures, resulting in unique amplifications in each parasite species.…”
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  4. 3384

    The mediating effect of anxiety and depression on the association between adverse experiences and executive functioning in young adults by Juan Francisco Palomares Gómez, Anyerson Stiths Gómez Tabares, Catalina Gallego Montes

    Published 2024-12-01
    “…EF of working memory (WAIS-IV Working Memory Index), shifting (Wisconsin Card Sorting Test - WSCT), inhibitory control (Test of Colors and Words - STROOP), anxiety (Trait-State Anxiety Inventory - IDARE), depression (Beck Depression Inventory-II) and ACEs (Fellity ACEs Questionnaire) were measured. Results: ACEs have strong and direct effects on anxiety and depression, moderate effects on executive functioning, and emotional variables have a weak impact on executive functioning. …”
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  5. 3385

    Ramp Metering for a Distant Downstream Bottleneck Using Reinforcement Learning with Value Function Approximation by Yue Zhou, Kaan Ozbay, Pushkin Kachroo, Fan Zuo

    Published 2020-01-01
    “…This is because under the control of a conventional linear feedback-type ramp metering strategy, when metered traffic from the ramp arrive at the distant downstream bottleneck, the state of the bottleneck may have significantly changed from when it is sampled for computing the metering rate; due to the considerable time, these traffic will have to take to traverse the long distance between the ramp and the bottleneck. …”
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  6. 3386

    A reporter assay in lamprey embryos reveals both functional conservation and elaboration of vertebrate enhancers. by Hugo J Parker, Tatjana Sauka-Spengler, Marianne Bronner, Greg Elgar

    Published 2014-01-01
    “…We find instances of both functional conservation and lineage-specific functional evolution of CNEs across vertebrates, emphasising the utility of functionally testing homologous CNEs in their host species.…”
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  7. 3387

    Mitochondrial function: A new direction for the targeted treatment of cardiovascular diseases with Chinese herbal medicine by Lin Yang, Liang Wang, Baofeng Yang, Yue Zhang

    Published 2025-03-01
    “…Recent studies have found that traditional Chinese medicine (TCM) possesses the potential to effectively address cardiovascular diseases while enhancing the structural integrity and functional capacity of mitochondria. …”
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  8. 3388
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  10. 3390

    A Clinical Study on Functional Outcome of Percutaneous Transforaminal Endoscopic Discectomy under Local Anesthesia by Suryansh Nema, Varun Kumar Agarwal

    Published 2023-07-01
    “…Background: Many surgical approaches from conventional open discectomy, microdiscectomy, percutaneous endoscopic interlaminar discectomy, and transforaminal endoscopic discectomy have been used for the treatment of prolapsed intervertebral disc. …”
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  11. 3391

    NEGATIVE SYMPTOMS IN SCHIZOPHRENIA – CLINICAL FEATURES, DIFFERENTIAL DIAGNOSTIC MARKERS, ETIOPATHOGENIC MECHANISMS, AND FUNCTIONAL IMPACT by Dania Andreea Radu, Catalin Oprea, Ilinca Untu, Roxana Chirita

    Published 2025-06-01
    “…Although a paradigm shift has occurred and negative symptoms are now acknowledged as the main cause of impaired functioning in patients with schizophrenia, scientific advancements have not yet provided a viable solution for their complete eradication. …”
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  14. 3394

    Molecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein Function. by Mojca Tajnik, Malgorzata Ewa Rogalska, Erica Bussani, Elena Barbon, Dario Balestra, Mirko Pinotti, Franco Pagani

    Published 2016-05-01
    “…In addition, our results have a significant impact in the development of splicing-switching therapies in particular for mutations that affect both splicing and protein function where increasing the amount of a correctly spliced protein can circumvent the basic functional defects.…”
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  15. 3395

    A New Mathematical Model for Flank Wear Prediction Using Functional Data Analysis Methodology by Sonja Jozić, Branimir Lela, Dražen Bajić

    Published 2014-01-01
    “…In order to be able to predict flank wear a new linear regression mathematical model has been developed by utilizing functional data analysis methodology. Regression coefficients of the model are in the form of time dependent functions that have been determined through the use of functional data analysis methodology. …”
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  16. 3396

    Functional Test Scales for Evaluating Cell-Based Therapies in Animal Models of Spinal Cord Injury by Woon Ryoung Kim, Minjin Kang, Heejoo Park, Hyun-Joo Ham, Hyunji Lee, Dongho Geum

    Published 2017-01-01
    “…However, as there is no cure for the deficits produced by SCI, various therapeutic strategies have been examined using animal models. Due to the lack of standardized functional assessment tools for use in such models, it is important to choose a suitable animal model and precise behavioral test when evaluating the efficacy of potential SCI treatments. …”
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  17. 3397

    EMG biofeedback and functional magnetic resonance imaging in the post-stroke rehabilitation (precise grip training) by L. A. Chernikova, M. Ye. Ioffe, S. N. Busheneva, M. V. Shestakova, A. Ye. Bilimenko

    Published 2010-04-01
    “…Thus, fMRI and the clinical analysis have shown that EMG biofeedback training of the precision grip have the goal-directed and effective influence upon processes of functional reorganization of motor systems.…”
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  18. 3398

    Systemic functional grammar: a tool to investigate the lexicogrammatical complexification of advanced portuguese-efl interlanguage by Pedro H. L. Praxedes Filho

    Published 2004-01-01
    “…The narratives would be considered to bear a high level of complexification if they had more than 80% of complete clauses in terms of transitivity and mood configurational functions. The hypothesis that the spoken and written narratives would have a high level of complexification separately (87.61% and 94.14%) and together (90.72%) was confirmed, and so was the hypothesis that the written narratives would present an even higher level. …”
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    Podocyte-Specific Deletion of Murine CXADR Does Not Impair Podocyte Development, Function or Stress Response. by Christoph Schell, Oliver Kretz, Andreas Bregenzer, Manuel Rogg, Martin Helmstädter, Ulrike Lisewski, Michael Gotthardt, Pierre-Louis Tharaux, Tobias B Huber, Florian Grahammer

    Published 2015-01-01
    “…We therefore used a conditional transgenic approach to elucidate the function of Cxadr for podocyte development and stress response. …”
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