Clinical phenotype and functional influence of GRIN2A variants in epilepsy‐aphasia syndrome by Lu Zhang, Yiran Duan, Rui Ma, Jiaqi Han, Na Pan, Lehong Gao, Yuping Wang

“…Abstract Objective N‐methyl‐D‐aspartate receptors are glutamate‐gated ion channels that play a crucial role in brain function. Numerous inherited or de novo variants in the GRIN2A gene, encoding the GluN2A subunit of the receptor, have been identified in patients with epilepsy. …”
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Photosystems functioning, the content of chemical elements, flavonoids and brassinosteroids in leaves of chimera Cornus controversa by A. F. Likhanov, V. V. Schwartau, N. V. Zaimenko, N. P. Didyk, O. V. Grygorieva, I. P. Kharytonova, O. I. Dziuba, O. V. Zakrasov, M. Yu. Zhurba, N. A. Pavliuchenko

“…The purpose of this work was to conduct a comparative study of the photosynthetic apparatus functioning, the content of macro-, microelements, flavonoids and brassinosteroids in the variegated and green leaves of the periclinal chimera Cornus controversa plant grown in the collection of M. …”
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Latent class analysis identifies functional decline with Amsterdam IADL in preclinical Alzheimer's disease by Sarah‐Christine Villeneuve, Marion Houot, Federica Cacciamani, Merike Verrijp, Bruno Dubois, Sietske Sikkes, Stéphane Epelbaum, MEMENTO study group and the INSIGHT‐preAD study group, Hovagim Bakardjian, Habib Benali, Hugo Bertin, Joel Bonheur LaurieBoukadida, Nadia Boukerrou, Enrica Cavedo, Patrizia Chiesa, Olivier Colliot, Bruno Dubois, Marion Dubois, Stéphane Epelbaum, Geoffroy Gagliardi, Remy Genthon, Marie‐Odile Habert, Harald Hampel, Marion Houot, Aurélie Kas, Foudil Lamari, Marcel Levy, Simone Lista, Christiane Metzinger, Fanny Mochel, Francis Nyasse, Catherine Poisson, Marie‐Claude Potier, Marie Revillon, Antonio Santos, Katia Santos Andrade, Marine Sole, Mohmed Surtee, Michel Thiebaud de Schotten, Andrea Vergallo, Nadjia Younsi

“…Results No overall functional decline related to AD imaging markers was evidenced. …”
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Designing novel “Smell-Aids” to improve olfactory function in post COVID-19 era by Veronica L. Formanek, Barak M. Spector, Gabriela Zappitelli, Zhenxing Wu, Kai Zhao

“…., all serve to enhance the sensory stimuli to enable patients to see or hear things that they would not otherwise be able to, but we have no equivalent technology for olfaction, a pressing issue in the post-COVID era. …”
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Association between physical and cognitive function in post menopause: a cross-sectional study by Wellington Gilberto de Sousa, Luanna Rodrigues Margato, Danyelle Cristina Silva Pelet, Rodolfo Ferreira de Paula, Anderson Diogo de Souza Lino, Fábio Lera Orsatti, Markus Vinicius Campos Souza

“… Functional tests have been performed to predict cognitive decline in postmenopausal women and may be an important tool to identify early reductions in cognitive performance in this population. …”
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CD63 Immunological Activation Versus Hemostatic Function: Platelet Alterations After Polytrauma by Gregor Roemmermann, Olivia Bohe, Laura Heimann, Franziska Wirth, Franziska Drumm, Peter Biberthaler, Philipp Moog, Christina Schwenk, Nadja Muehlhaupt, Li Wan, Marc Hanschen

“…The exact mechanisms, particularly the link between immune response and hemostasis, have not been conclusively established. This study aimed to investigate the activity marker CD63 on platelets after polytrauma and its significance for hemostasis. …”
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Outcomes of K-Clip Implantation for Functional Tricuspid Regurgitation Accompanied with Persistent Atrial Fibrillation by Da-Wei Lin, Ling-Wei Zou, Jia-Xin Miao, Jia-Ning Fan, Min-Fang Meng, Yi-Ming Qi, Zhi Zhan, Wen-Zhi Pan, Da-Xin Zhou, Xiao-Chun Zhang, Jun-Bo Ge

“…<b>Background:</b> Atrial fibrillation (AF) has been identified as a risk factor for functional tricuspid regurgitation (FTR) in the absence of other known etiologies, although limited interventional options are available. …”
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FUNCTIONAL RESPONSE TO ENDOBRONCHIAL VALVE IMPLANTING TO THOSE SUFFERING FROM PULMONARY DESTRUCTIVE TUBERCULOSIS by L. A. Popova, E. A. Shergina, O. V. Lovacheva, T. R. Bagdasaryan, N. A. Chernykh, V. B. Nefedov

“…The changes in the pulmonary ventilation capacity (VC, FEV1 , FEV1 /VC%, PEF, MEF25,75) and blood gases (РаО2 , РаСО2, SaО2 %) before and in 4-6 weeks after EV installation have been studied.Results. After 1-1.5 months after EV installation no significant changes in the pulmonary ventilation function were found in 62.2% of patients, 43.2% of patients demonstrated no significant changes in gas exchange function and there were certain changes in the remaining patients. …”
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Novel Loss of Function Variant in SOST From Chinese Family Results in Sclerosteosis 1 by Yufan Guo, Xintao Wu, Yuting Jin, Yu Gu, Yuting Lou, Pu Miao, Ye Wang, Bijun Zhang, Xueting Lin, Chudi Zhang, Jianhua Feng

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Identification and functional characterisation of DNA methylation differences between East- and West-originating Finns by Joanna Ciantar, Saara Marttila, Sonja Rajić, Daria Kostiniuk, Pashupati P Mishra, Leo-Pekka Lyytikäinen, Nina Mononen, Marcus E Kleber, Winfried März, Mika Kähönen, Olli Raitakari, Terho Lehtimäki, Emma Raitoharju

“…Our results indicate that DNA methylation differences between East and West Finns may have a functional role in mediating the cardiometabolic disease discrepancy between the sub-populations.…”
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Simulated Gastrointestinal Fluids Impact the Stability of Polymer-Functionalized Selenium Nanoparticles: Physicochemical Aspects by Selmani A, Matijaković Mlinarić N, Falsone SF, Vidaković I, Leitinger G, Delač I, Radatović B, Nemet I, Rončević S, Bernkop-Schnürch A, Vuletić T, Kornmueller K, Roblegg E, Prassl R

“…Selenium nanoparticles (SeNPs) have demonstrated improved bioavailability compared to both inorganic and organic forms of Se. …”
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Curcumin Promotes the Recovery of Motor Function After Brachial Plexus Avulsion Injury in Rats by Sijing Li, Bing He, Guijuan Zhou, Lin Wu, Xuanwei Wen, Limin Deng, Shudong Lin, Guozhi Liu, Shuangxi Chen, Zijian Xiao

“…ABSTRACT Background and Purpose Brachial plexus root avulsion (BPRA) often results in the loss of upper limb motor function. Curcumin (CUR) has been proven to have neuroprotective properties in various neurological disorders due to the effects of anti‐oxidative stress and anti‐inflammation. …”
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Glioma-Associated Antigen HEATR1 Induces Functional Cytotoxic T Lymphocytes in Patients with Glioma by Zhe Bao Wu, Chao Qiu, An Li Zhang, Lin Cai, Shao Jian Lin, Yu Yao, Qi Sheng Tang, Ming Xu, Wei Hua, Yi Wei Chu, Ying Mao, Jian Hong Zhu, Jianqing Xu, Liang Fu Zhou

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Effects of traditional Chinese exercises on cardiopulmonary function in stroke patients: A meta-analysis by Danmeng Tong, Hongyu Li, Wei Zhao, Wang Guo, Bin Chen, Qiang Tang

“…Conclusions: Traditional Chinese exercise positively influences cardiorespiratory function in stroke patients, demonstrating the most significant improvements in athletic endurance and cardiac function. …”
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Noncoding RNA-encoded peptides in cancer: biological functions, posttranslational modifications and therapeutic potential by Shiming Tan, Wenjuan Yang, Zongyao Ren, Qiu Peng, Xuemeng Xu, Xianjie Jiang, Zhu Wu, Linda Oyang, Xia Luo, Jinguan Lin, Longzheng Xia, Mingjing Peng, Nayiyuan Wu, Yanyan Tang, Yaqian Han, Qianjin Liao, Yujuan Zhou

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Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC by Xiyu Song, Xiyu Song, Xiyu Song, Jianhua Jiao, Jianhua Jiao, Jiayang Qin, Wei Zhang, Weijun Qin, Weijun Qin, Shuaijun Ma, Shuaijun Ma

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Effects of vitamin A supplementation on visual function in healthy adults: A systematic review by Kavous Shahsavarinia, Ali Mostafaei, Nooshin Milanchian, Leila Roshangar, Parastu Fallahi, Moloud Balafar, Robab Mehdipour, Fereshteh Farhadi, Hassan Soleimanpour, Nasim Hajipoor, Reza Mohammadi, Hanieh Salehi-Pourmehr

“…Vitamin A plays an important role in various bodily functions, including vision. This systematic review aimed to synthesize the available evidence on the effects of vitamin A supplementation on visual function in healthy adults. …”
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Effects of prior air pollution exposure on functional recovery after a myocardial infarction by Jordi Bañeras, Alejandro Berenguel-Senén, Eulogio Pleguezuelos, José Antonio Alarcón, Jesús Vallejo, Paz Sanz-Ayán, Juan Izquierdo-García, José Garcia, Rafael Colman, Juan Ignacio Castillo-Martín, Eduard Ródenas-Alesina

“…This study highlights the importance of air pollution during cardiac rehabilitation and suggests that NO2 negatively impact on post-MI functional recovery.…”
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Functional aptamer evolution-enabled elucidation of a melanoma migration-related bioactive epitope by Hong Xuan, Siqi Bian, Qinguo Liu, Jun Li, Shaojin Li, Sharpkate Shaker, Haiyan Cao, Tongxuan Wei, Panzhu Yao, Yifan Chen, Xiyang Liu, Ruidong Xue, Youbo Zhang, Liqin Zhang

“…Aptamers present a promising avenue as they can explore membrane proteomes and have the potential to interfere with cell function. …”
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Inflammatory conditions shape phenotypic and functional characteristics of lung-resident memory T cells in mice by Anna Schmidt, Jana Fuchs, Mark Dedden, Katharina Kocher, Christine Schülein, Julian Hübner, Ana Vieira Antão, Pascal Irrgang, Friederike Oltmanns, Vera Viherlehto, Natascha Leicht, Ralf Joachim Rieker, Carol Geppert, Uwe Appelt, Sebastian Zundler, Kilian Schober, Dennis Lapuente, Matthias Tenbusch

“…Our preclinical work thus confirms that inflammatory conditions in the tissue shape the phenotypic and functional characteristics of TRM to serve relevant informations for optimizing mucosal vaccines.…”
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