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Identification of presenilin mutations that have sufficient gamma-secretase proteolytic activity to mediate Notch signaling but disrupt organelle and neuronal health
Published 2025-08-01“…While the association of PSEN mutations with familial AD have been known for over 20 years, the mechanism underlying the impact these mutations have on disease is not fully understood. …”
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Patients with Coronary Artery Disease Have Lower Levels of Antibody to Heat-Stressed Fibroblast Derived Proteins, versus Normal Subjects
Published 2021-01-01“…Fibroblasts constitute 60-70% of cardiac cells and have a crucial role in cardiovascular function. Hence, the aim of this study was to show a potential therapeutic application of proteins derived from heat-stressed fibroblast in CAD patients. …”
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An Algorithm for Restoring a Function from Different Functionals for Predicting Rare Events in the Economy
Published 2022-07-01“…This paper aims to restore some parameters of functionals using cubic splines to forecast rare events in finance and economics. …”
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Software Development and Maintenance Effort Estimation Using Function Points and Simpler Functional Measures
Published 2024-10-01“…After the introduction of Function Points, a few “simplified” measures have been proposed, aiming to make measurement simpler and applicable when fully detailed software specifications are not yet available. …”
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Magnons from time-dependent density-functional perturbation theory and nonempirical Hubbard functionals
Published 2025-04-01“…Abstract Spin excitations play a fundamental role in understanding magnetic properties of materials, and have significant technological implications for magnonic devices. …”
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Acute Effects of Cannabis Inhalation on Arterial Stiffness, Vascular Endothelial Function, and Cardiac Function
Published 2024-12-01“…Although evidence links chronic use to an increased risk of disease and adverse cardiovascular events, few studies have investigated the acute effects of cannabis inhalation on subclinical dysfunction. …”
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Improving Fourier Partial Sum Approximation for Discontinuous Functions Using a Weight Function
Published 2017-01-01“…Using wm(r;x), we develop a weighted averaging method in order to improve Fourier partial sum approximation for a function having a jump-discontinuity. The method is based on the decomposition of the target function into the left-hand and the right-hand part extensions. …”
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Analysis of the effects of eating and emotions on reproductive axis function in patients with functional hypothalamic amenorrhea
Published 2024-12-01“…Objective: To investigate the effects of eating and emotions on reproductive axis function in patients with functional hypothalamic amenorrhea (FHA).Methods: A retrospective cohort study was conducted to summarize the clinical and endocrine characteristics of 58 patients with FHA at initial diagnosis and to follow up the recovery of ovulation and spontaneous menstruation in the patients to investigate these biochemical indicators and their effects on recovery outcomes.Results: Among patients with FHA, 13.8% (8/58) and 15.5% (9/58) had above moderately severe depressive and severe anxiety symptoms respectively, and 25.9% (15/58) were at high risk for eating disorders. 34.5% (20/58) were included assessed as having recovered. …”
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Humans may not have a uniquely enhanced sequence memory: sequence discrimination is facilitated by causal–logical framing in humans and chimpanzees
Published 2025-07-01“…Humans have been suggested to possess uniquely enhanced memory for sequences, based on sequence discrimination learning (SDL) tasks involving arbitrarily ordered sequences with no functional connection to outcomes. …”
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The prevalence of post-abortion syndrome in patients presenting at Kalafong hospital's family medicine clinic after having a termination of pregnancy
Published 2004-06-01“…To fulfill the criteria of PAS, the symptoms should have been present for more than a month and must have affected the subject's daily functioning. …”
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Hepatitis B virus genotypes A1 and A2 have distinct replication phenotypes due to polymorphisms in the HBx gene.
Published 2025-01-01“…Individuals infected with these two subtypes appear to have different clinical manifestations and virologic features. …”
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Do olfactory and gustatory psychophysical scores have prognostic value in COVID-19 patients? A prospective study of 106 patients
Published 2020-08-01“…Methods Multicentre prospective study that recruited 106 COVID-19 subjects at diagnosis. Chemosensitive functions were assessed with psychophysical tests within 4 days of clinical onset, at 10 and 20 days. …”
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Harmonic functions of class of Bazilevi´c type Related to new derivative operator
Published 2019-08-01“…In this paper, we define and investigate subclass of Bazilevi´c type harmonic univalent functions related with a new linear operator. Also, we have obtained the harmonic structures in terms of its coefficient bounds, extreme points, distortion bound, convolution and we proved the function belongs to this class be closed under an integral operator.…”
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