Suggested Topics within your search.
Suggested Topics within your search.
-
2541
Comparison of the effects of mixed tempeh with soy tempeh on cognitive function in older people
Published 2025-05-01Get full text
Article -
2542
TET1 displays catalytic and non-catalytic functions in the adult mouse cortex
Published 2024-12-01“…However, deletion of Tet1 precludes the disentangling of the catalytic and non-catalytic functions of TET1. Here, we dissect these functions of TET1 by comparing adult cortex of Tet1 wildtype (Tet1 WT), a novel Tet1 catalytically dead mutant (Tet1 HxD), and Tet1 knockout (Tet1 KO) mice. …”
Get full text
Article -
2543
Diagnostic value of noninvasive comprehensive morphological and functional assessment of coronary artery disease
Published 2019-01-01“…Recently adopted technique, Transthoracic Doppler Echocardiography (TDE) enables the estimate of functional significance of coronary luminal narrowing. …”
Get full text
Article -
2544
Effect of allopurinol on renal function in chronic kidney disease patients with asymptomatic hyperuricemia
Published 2017-01-01“…Objective To investigate the effect of allopurinol treatment on renal function in chronic kidney disease(CKD) patients with asymptomatic hyperuricemia.Methods Select the patients whom diagnosed CKD 2~3a phase with asymptomatic hyperuricemia from February 2014 to February2015 in nephrology department of yangzhou NO.1 people’s hospital.All patients were randomly divided into allopurinol treatmenl group and control group.Both groups treated with low salt,low fat,low protein and low purine diet,control blood pressure and blood glucose.Allopurinol treatment group received allopurinol 200 mg per day,the control group was not given uric acid lowering treatment One year after the treatment,observing two groups of eGFR,albuminuria and blood pressure in patients.Results In allopurinol treatment group,3 patients withdrawal due to rash,the incidence rate is7.14%.Allopurinol treatment significantly lower blood uric acid levels after 1 year later(515.28 ±114.13 vs 280.21 ± 72.58,P<0.01),the eGFR has no obvious change before and after the treatment(73.46 ± 18.38 vs 70.37 ± 20.11,P>0.05),while control group’s blood uric acid higher(487.02 ±78.57 vs 545.43 ± 89.56,P<0.05)and eGFR decline dramatically in a year later(70.43 ± 20.65 vs64.21 ± 17.42,P<0.05).In allopurinol treatment group,the level of proteinuria decreased slightly(0.62 ± 0.43 vs 0.48 ± 0.12,P>0.05),but there was no statistical significance(P>0.05),in the control group,albuminuria have no difference before and after treatment(0.60 ± 0.47 vs 0.64 ± 0.37,P>0.05).Systolic blood pressure(155.44±12.12 vs 125.21 ± 10.08,P<0.05;157.42 ± 14.12 vs128.45 ± 9.64,P<0.05) and diastolic blood pressure(88.56 ± 10.21 vs 80.45 ± 9.23,P<0.05;86.45 ± 11.56 vs 82.27 ± 6.25,P<0.05) were significantly lower than before after treatment in both groups,but there was no statistical difference between the two groups(P>0.05).Conclusions Allopurinol slowed the decline of eGFR in CKD 2~3a phase with asymptomatic hyperuricemia.…”
Get full text
Article -
2545
Functional positioning in robotic patello-femoral arthroplasty: a step-by-step technique
Published 2025-01-01“…Recent advances in implant design and robotic-assisted techniques have contributed to more personalized and reproducible procedures. …”
Get full text
Article -
2546
Distinct functional cerebral hypersensitivity networks during incisional and inflammatory pain in rats
Published 2025-06-01“…We developed a comprehensive framework for brain network analysis combining functional magnetic resonance imaging (MRI) with graph-theory (GT) and data classification by linear discriminant analysis. …”
Get full text
Article -
2547
-
2548
Acute Effect of a Single Functional Neurology Intervention on Muscular Trigger Point
Published 2025-02-01“…This study aimed to assess the effectiveness of a functional neurology intervention in reducing pain and improving muscle function in patients with MTrPs in the upper trapezius muscle. …”
Get full text
Article -
2549
Regularized regression outperforms trees for predicting cognitive function in the Health and Retirement Study
Published 2025-09-01“…Background: Generalized linear models have been favored in healthcare research due to their interpretability. …”
Get full text
Article -
2550
Functions and Therapeutic Potentials of Long Noncoding RNA in Skeletal Muscle Atrophy and Dystrophy
Published 2025-04-01“…Finally, we explored the potential of using these lncRNAs as therapeutic targets for muscle atrophy and muscular dystrophy, including the methods of discovery and clinical application prospects for functional lncRNAs.…”
Get full text
Article -
2551
Resting-state functional connectivity changes following audio-tactile speech training
Published 2025-04-01“…In this study, we used resting-state functional magnetic resonance imaging (rsfMRI) to measure spontaneous low-frequency oscillations in the brain while at rest to assess training-induced changes in functional connectivity. …”
Get full text
Article -
2552
The Effect of Sex Differences on Endothelial Function and Circulating Endothelial Progenitor Cells in Hypertriglyceridemia
Published 2020-01-01“…Background. Men have a higher risk and earlier onset of cardiovascular diseases compared with premenopausal women. …”
Get full text
Article -
2553
Diagnostic Challenges: A Review of Non Classic Thyroid Function Test Patterns
Published 2025-01-01“…Disorders of thyroid function are common. Aside from some obvious presenting features of thyroid disease, such as goitre, which can easily be identified, patients with thyroid conditions may present with non specific symptoms. …”
Get full text
Article -
2554
The function of a spindle checkpoint gene bub-1 in C. elegans development.
Published 2009-06-01“…Studies in yeast have shown that BUB1 functions as a spindle checkpoint protein by regulating the anaphase promoting complex/cyclosome (APC/C). …”
Get full text
Article -
2555
Multi-scale machine learning model predicts muscle and functional disease progression
Published 2025-07-01“…The stage 3 model, which combined functional muscle groups, predicted change in TUG with a RMSE of 0.6 s in the holdout testing dataset. …”
Get full text
Article -
2556
Mitochondrial functional impairment in ARL3‐mutation related rod‐cone dystrophy
Published 2024-11-01“…Abstract Mitochondria are vital for retinal cell function and survival, and there is growing evidence linking mitochondrial dysfunction to retinal degenerations. …”
Get full text
Article -
2557
Evaluation of the long-term effects of COVID-19 on pulmonary functions in recovered patients
Published 2024-12-01“…Background: It is documented that COVID-19 survivors have prolonged morbidity and functional impairment for many years. …”
Get full text
Article -
2558
Altered Brain Activity and Functional Connectivity in Unilateral Sudden Sensorineural Hearing Loss
Published 2020-01-01“…Although many studies have analyzed altered brain function in populations with hearing loss, little information is available about patients with idiopathic SSNHL. …”
Get full text
Article -
2559
The goat milk composition and properties as a raw material for functional foods manufacturing
Published 2023-12-01“…Based on the data obtained, it is proposed to use goat's milk as the main component in the development of functional food products. It is believed that the use of goat's milk can contribute to improving the health and quality of life of people, especially those who need additional nutrients or have specific dietary needs. …”
Get full text
Article -
2560
Structural and functional correlations in the pre-perimetric and the initial stages of glaucomatous optic neuropathy
Published 2021-06-01“…Purpose:to study morphological and functional relationships in the early and preclinical diagnosis of glaucomatous optical neuropathy based on optical coherence tomography (OCT) of the retina and the data of electrophysiological research. …”
Get full text
Article