Characteristics of the Small Bowel Lesions Detected by Capsule Endoscopy in Patients with Chronic Kidney Disease by Harunobu Kawamura, Eiji Sakai, Hiroki Endo, Leo Taniguchi, Yasuo Hata, Akiko Ezuka, Hajime Nagase, Takaomi Kessoku, Eiji Yamada, Hidenori Ohkubo, Takuma Higrashi, Yusuke Sekino, Tomoko Koide, Hiroshi Iida, Takashi Nonaka, Hirokazu Takahashi, Masahiko Inamori, Shin Maeda, Atsushi Nakajima

“…The incidence of small-bowel vascular lesions was significantly higher in CKD patients than in age-and-sex matched non-CKD patients (P<0.001). On the other hand, there was any significant difference of the incidence of small-bowel lesions between HD and non-HD patients. …”
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Development of a Recombinant Omicron BA.1 Subunit Vaccine Candidate in Pichia pastoris by Sibel Kalyoncu, Dogu Sayili, Ayca Zeybek Kuyucu, Hakan Soyturk, Seyda Gullu, Busra Ersayan, Ibrahim Oguzhan Tarman, Mehmet Ender Avci, Olcay Mert, Umut Haskok, Ege Tekin, Huseyin Akinturk, Ridvan Orkut, Aysegul Demirtas, Idil Tilmensagir, Ceren Ulker, Bilgi Gungor, Mehmet Inan

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The relationship between tumour necrosis, systemic inflammation, body composition and survival in patients with colon cancer by Ross D. Dolan, Kathryn Pennel, Joshua Thompson, Molly McKenzie, Peter Alexander, Colin Richards, Douglas Black, Tanvir Abbass, Noori Maka, Josh McGovern, Antonia Roseweir, Stephen T. McSorley, Paul G. Horgan, Campbell Roxburgh, Donald C. McMillan, Joanne Edwards

“…Of these, 70.4% were over 65 years of age, 54.8% were male and 49.8% had an ASA grade of 1 or 2. Pathological examination showed that the majority of patients had a T3 (53.7%) or a T4 (34.0%) cancer and 73.0% had evidence of necrosis. …”
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Paratubular basement membrane insudative lesions predict renal prognosis in patients with type 2 diabetes and biopsy-proven diabetic nephropathy. by Koki Mise, Yutaka Yamaguchi, Junichi Hoshino, Toshiharu Ueno, Akinari Sekine, Keiichi Sumida, Masayuki Yamanouchi, Noriko Hayami, Tatsuya Suwabe, Rikako Hiramatsu, Eiko Hasegawa, Naoki Sawa, Takeshi Fujii, Shigeko Hara, Hitoshi Sugiyama, Hirofumi Makino, Jun Wada, Kenichi Ohashi, Kenmei Takaichi, Yoshifumi Ubara

“…However, paratubular basement membrane insudative lesions (PTBMIL) have not attracted much attention, and the association between such lesions and the renal prognosis remains unclear.…”
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Machine learning analysis of pathological images to predict 1-year progression-free survival of immunotherapy in patients with small-cell lung cancer by Hirotaka Matsumoto, Hiroaki Akamatsu, Nobuyuki Yamamoto, Yuki Sato, Daichi Fujimoto, Yoshihiko Taniguchi, Motohiro Tamiya, Yasuhiro Koh, Junya Fukuoka, Hisashi Tanaka, Naoki Furuya, Ryota Shibaki, Tsukasa Nozawa, Akira Sano, Yuka Kitamura, Takashi Kijima, Toshihide Yokoyama, Satoru Miura, Akito Hata, Jun Sugisaka

“…The machine learning analysis of the TIME had better accuracy than the human count evaluations (AUC of human count, CD8-positive lymphocyte: 0.681, FoxP3-positive lymphocytes: 0.626, PD-L1 score: 0.567).Conclusions The spatial analysis of the TIME using machine learning predicted the immunotherapy efficacy in patients with SCLC, thus supporting its role as an immunotherapy biomarker.…”
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Obesity increases DNA damage in the breast epithelium by Mohamed Gaber, Arnaud Quentel, Julia Holmes, Cassandra Lepetit, Hana Triki, Adam Wilson, Valerie Payne, Iliana Tenvooren, Cloé Dehours, Abigail Peoples, Mary L. Duet, Adam J. Katz, Thierry Pécot, Gwenola Bougras-Cartron, Pierre-François Cartron, Katherine L. Cook, Pierre-Alexandre Vidi

“…Compared to non-Hispanic Whites, women identifying as African Americans had higher levels of DNA breaks, as well as elevated leptin and IGF-1. …”
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ESPGHAN and NASPGHAN 2024 protocol for paediatric functional constipation treatment guidelines (standard operating procedure) by Marc A Benninga, Morris Gordon, Nikhil Thapar, Osvaldo Borrelli, Vassiliki Sinopoulou, Merit Tabbers, Anil Darbari, Julie Khlevner, Anna de Geus, Marcin Banasiuk, Mary Boruta, Dawn Dore-Stites, Michelle Gould, Juliette Hawa, Kirsten Brooke Jones, Alexandra Kilgore, Hayat Mousa, Samuel Nurko

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Seroprevalence of Leptospira spp. antibodies in humans and livestock at various human-animal interfaces in Jordan by Zuhair Bani Ismail, Lea Widemann, Yasmin Daradkeh, Omar Al-Omari, Alaa Fahmawi, Mais Lakaideh, Belal Sha’fout, Haia Mellhem, Leen Al-Bayari, Saad Al-Omari, Hani Talafha, Zaidoun Hijazeen, Bilal Al-Omari, Jean DeMarco, William B. Karesh, Ehab A. Abu-Basha

“…For humans, seroprevalence was calculated from baseline data, and incidence was calculated using follow-up data. …”
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Development and preclinical testing of a naloxone prodrug depot for extended protection against opioid overdose by Hala Aldawod, Arjun D. Patel, Rasha Emara, Dengpan Liang, Joshua S. Ho, Toufiq Ul Amin, Md Tariqul Haque Tuhin, Abdulmalek Balgoname, Avishan Kiani, Jumana M. Ajlouny, Melanie A. Felmlee, Miki S. Park, Bhaskara R. Jasti, William K. Chan, James A. Uchizono, Mamoun M. Alhamadsheh

“…The opioid antidote naloxone has a short action ( ~ 1 hour), requiring repeated doses. …”
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Adipocyte heterogeneity and tumor infiltration of adipose tissue in patients with metastatic breast cancer by Hava Izci, Gitte Zels, Anirudh Pabba, Marion Maetens, François Richard, Maxim De Schepper, Josephine Van Cauwenberge, Ha-Linh Nguyen, Kristien Borremans, Sophia Leduc, Karen Van Baelen, Sigrid Hatse, Tatjana Geukens, Amena Mahdami, Hans Wildiers, Patrick Neven, Wouter Van Den Bogaert, Giuseppe Floris, Christine Desmedt

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A new class of natural anthelmintics targeting lipid metabolism by Hala Zahreddine Fahs, Fathima S. Refai, Suma Gopinadhan, Yasmine Moussa, Hin Hark Gan, Yamanappa Hunashal, Gennaro Battaglia, Patricia G. Cipriani, Claire Ciancia, Nabil Rahiman, Stephan Kremb, Xin Xie, Yanthe E. Pearson, Glenn L. Butterfoss, Rick M. Maizels, Gennaro Esposito, Antony P. Page, Kristin C. Gunsalus, Fabio Piano

“…AFA shows significant efficacy in H. polygyrus infected mice. …”
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Hobbit: Providing Fall Detection and Prevention for the Elderly in the Real World by Markus Bajones, David Fischinger, Astrid Weiss, Daniel Wolf, Markus Vincze, Paloma de la Puente, Tobias Körtner, Markus Weninger, Konstantinos Papoutsakis, Damien Michel, Ammar Qammaz, Paschalis Panteleris, Michalis Foukarakis, Ilia Adami, Danai Ioannidi, Asterios Leonidis, Margherita Antona, Antonis Argyros, Peter Mayer, Paul Panek, Håkan Eftring, Susanne Frennert

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Use of explainable AI on slit-lamp images of anterior surface of eyes to diagnose allergic conjunctival diseases by Michiko Yonehara, Yuji Nakagawa, Yuji Ayatsuka, Yuko Hara, Jun Shoji, Nobuyuki Ebihara, Takenori Inomata, Tianxiang Huang, Ken Nagino, Ken Fukuda, Tatsuma Kishimoto, Tamaki Sumi, Atsuki Fukushima, Hiroshi Fujishima, Moeko Kawai, Etsuko Takamura, Eiichi Uchio, Kenichi Namba, Ayumi Koyama, Tomoko Haruki, Shin-ich Sasaki, Yumiko Shimizu, Dai Miyazaki

“…The pipeline had a high classification performance, and the area under the curve (AUC) was 0.959 for AC, 0.905 for normal subjects, 0.847 for GPC, 0.829 for VKC, and 0.790 for AKC. …”
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Inférences sur les réseaux régionaux à partir d’arbres génétiques locaux, l’exemple du site néolithique de Gurgy 'les Noisats' by Maïté Rivollat, Adam Benjamin Rohrlach, Harald Ringbauer, Ainash Childebayeva, Fanny Mendisco, Rodrigo Barquera, András Szolek, Heidi Colleran, Mélie Le Roy, Jonathan Tuke, Franziska Aron, Marie-Hélène Pemonge, Ellen Späth, Philippe Télouk, Léonie Rey, Gwenaëlle Goude, Vincent Balter, Johannes Krause, Stéphane Rottier, Marie-France Deguilloux, Wolfgang Haak

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Proteasome inhibition enhances oncolytic reovirus therapy in multiple myeloma independently of its direct cytotoxic effects by Ada Alice Dona, Theophilus Tandoh, Lokesh Nigam, Mahmoud Singer, Enrico Caserta, Mariam Murtadha, Yinghui Zhu, Milad Moloudizargari, Preeti Sharma, Ottavio Napolitano, Janet Winchester, Arnab Chowdhury, Alex Pozhitkov, James F. Sanchez, Hawa Vahed, Guido Marcucci, Matt Coffey, Gerard Nuovo, Douglas W. Sborov, Flavia Pichiorri, Craig C Hofmeister

“…The combination with proteasome inhibitors (PIs) has shown to enhance RV therapeutic activity, but the mechanisms of action have not been fully elucidated. …”
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Automated chest CT three-dimensional quantification of body composition: adipose tissue and paravertebral muscle by Akinori Hata, Yohei Muraguchi, Minoru Nakatsugawa, Xinan Wang, Jiyeon Song, Noriaki Wada, Takuya Hino, Kota Aoyagi, Masami Kawagishi, Takuo Negishi, Vladimir I. Valtchinov, Mizuki Nishino, Akihiro Koga, Naoki Sugihara, Masahiro Ozaki, Gary M. Hunninghake, Noriyuki Tomiyama, Mark L. Schiebler, Yi Li, David C. Christiani, Hiroto Hatabu

“…For adipose tissue quantification, 77 patients were included, while 245 were used for muscle quantification. The data were split into training and test sets, with manual segmentation as the ground truth. …”
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Ellagic Acid from <i>Geranium thunbergii</i> and Antimalarial Activity of Korean Medicinal Plants by Hojong Jun, Joon-Hee Han, Min Hong, Fadhila Fitriana, Jadidan Hada Syahada, Wang-Jong Lee, Ernest Mazigo, Johnsy Mary Louis, Van-Truong Nguyen, Seok Ho Cha, Wanjoo Chun, Won Sun Park, Se Jin Lee, Sunghun Na, Soo-Ung Lee, Eun-Taek Han, Tae-Hyung Kwon, Jin-Hee Han

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Infantile BCG osteomyelitis ultimately diagnosed as a result of trauma by Katsuhiko Tabata, MD, Osamu Miyazaki, MD, Ayako Imai, MD, Reiko Okamoto, MD, Mikiko Miyasaka, MD, Yoshiyuki Tsutsumi, MD, Yoko Anami, MD, Atsuhito Seki, MD, Tatsuki Ikuse, MD, PhD, Toshinao Kawai, MD, PhD, Takashi Ishikawa, MD, PhD, Chizuko Haga, MD, Takako Yoshioka, MD, Shunsuke Nosaka, MD

“…Although the incidence of adverse reactions is low, disseminated lymphadenitis and osteomyelitis have been reported as potential side effects. We encountered a case of BCG osteomyelitis with typical imaging findings. …”
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Exome sequencing reveals IFT172 variants in patients with non-syndromic cholestatic liver disease. by Magdaléna Neřoldová, Elżbieta Ciara, Janka Slatinská, Soňa Fraňková, Petra Lišková, Radana Kotalová, Janka Globinovská, Markéta Šafaříková, Lucie Pfeiferová, Hana Zůnová, Lenka Mrázová, Viktor Stránecký, Alena Vrbacká, Ondřej Fabián, Eva Sticová, Daniela Skanderová, Jan Šperl, Marta Kalousová, Tomáš Zima, Milan Macek, Joanna Pawlowska, A S Knisely, Stanislav Kmoch, Milan Jirsa

“…(Lys56Thr) born to first cousins, had liver disease, interpreted on biopsy aged 4y as glycogen storage disease, followed by adult-onset nephronophthisis at 25y. …”
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