Gut microbiota differences linked to weight gain and ART in people living with HIV are enterotype specific and minor compared to the large differences linked to sexual behavior by Jan Kehrmann, Alireza Dostmohammadi, Anna-Lena Stumpf, Lara Best, Leah Consten, Hannah Sievert, Felix Maischack, Stefanie Sammet, Sarah Albayrak-Rena, Ann-Kathrin Doerr, Katharina Bohlen, Otgonzul von Velsen, Otgonzul von Velsen, Ivana Kraiselburd, Christina B. Karsten, Farnoush Farahpour, Farnoush Farahpour, Folker Meyer, Stefan Esser, Jan Buer

“…Of the 67 individuals forming a Prevotella-dominated enterotype cluster in principal coordinates analysis, 93% were men who had sex with men (MSM), while 31% of individuals in the Bacteroides-dominated enterotype cluster were MSM and 69% were non-MSM. …”
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From gut to joint: the protective impact of Eubacterium rectale on rheumatoid arthritis by Xiaoyang Liu, Xiaoyang Liu, Xiaoyang Liu, Ruihe Wu, Ruihe Wu, Ruihe Wu, Yuxin Fan, Yuxin Fan, Yuxin Fan, Kaili Qin, Kaili Qin, Kaili Qin, Baochen Li, Baochen Li, Baochen Li, Xiaofeng Li, Xiaofeng Li, Xiaofeng Li, Chong Gao, Caihong Wang, Caihong Wang, Caihong Wang

“…According to further MR analysis, Anaerostipes and E. rectale had a protective effect on RA, and reverse MR analysis showed no evidence of a causal relationship between these groups and RA. …”
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Construct and Predictive Validity of the Kansas City Cardiomyopathy Questionnaire in Adult Congenital Heart Disease by Ryan D. Byrne, MD, Ajith P. Nair, MD, Stephen J. Dolgner, MD, Swati Choudhry, MD, Edward J. Hickey, MD, Alexis C. Wood, PhD, Savitri Fedson, MD, Biykem Bozkurt, MD, PhD, Christopher R. Broda, MD

“…KCCQ was significantly lower for ACHD patients who experienced DH (66.0 vs 85.0; P = 0.002) or DP (53.5 vs 85.0; P = 0.001). Patients scoring ≤50 had significantly worse event-free survival (P = 0.004 for DH; P = 0.001 for DP). …”
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C-type lectin (SpCTL) through its binding to Spβ-integrin regulates antimicrobial peptide synthesis in mud crab (Scylla paramamosain) during Vibrio parahaemolyticus infection by Wei Yang, Yuyong He, Huifen Liang, Junyuan Lin, Ngoc Tuan Tran, Zhinuo Du, Ming Zhang, Ruhan Chen, Yuqing Zheng, Xu Meng, Shengkang Li

“…In this study, the mud crab SpCTL cDNA was cloned and functionally characterized. Phylogenetic analysis showed that SpCTL was closely related to Eriocheir sinensis with 81 % homology. …”
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Efficacy of Rikkunshito on Chemotherapy-Induced Nausea and Vomiting in Patients With Uterine Corpus or Cervical Cancer Treated With Cisplatin-Based Regimen-Placebo-controlled, Doub... by Yosuke Konno MD, Shunsuke Ohnishi MD, Shinichiro Minobe PhD, Eiji Nomura PhD, Takayuki Nagasawa PhD, Etsuko Fujimoto MD, Tatsuru Ohara PhD, Shin Nishio MD, Hisamori Kato PhD, Yoshihito Yokoyama PhD, Etsuko Miyagi PhD, Hideki Tokunaga PhD, Koji Nishino MD, Akira Kikuchi PhD, Yoshio Yoshida PhD, Takashi Iwata PhD, Daito Noguchi MD, Wataru Kudaka PhD, Shunsuke Oyamada PhD, Keisuke Ariyoshi PhD, Kota Kihara PhD, Hidemichi Watari MD

“…Conclusion: Rikkunshito had no additive effect on CINV prevention in patients with uterine corpus or cervical cancer who were treated with a cisplatin based regimen and standard antiemetics. …”
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Prognostic value of global plaque volume calculated from the 3D reconstruction of the coronary tree in patients without significant coronary artery disease. A multicenter study by Carlos Cortés, Julio Ruiz-Ruiz, Fernando Rivero, Ramón López-Palop, Octavio Jiménez, Alfonso Freites, Luis R. Gonçalves-Ramírez, María Rosario Ortas Nadal, Sara Blasco, Mario García-Gómez, Clara Fernández, Luca Scorpiglione, J. Alberto San Román Calvar, Ignacio J. Amat-Santos

“…This study aims to determine the prognostic value of the global plaque volume (GPV) in patients with stable coronary artery disease without functionally significant lesions at a 5-year follow-up. …”
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SLNP-based CDK4- targeted nanotherapy against glioblastoma by Uzma Ghani, Fareeha Khalid Ghori, Muhammad Usman Qamar, Muhammad Usman Qamar, Hina Khan, Basit Azad, Sabahat Habib, Saira Justin, Ishaq N. Khan, Ishaq N. Khan, Tawaf Ali Shah, Gamal A. Shazly, Mohammed Bourhia, Fouzia Perveen, Aneela Javed

“…Sil showed decreased cell viability 72 h after treatment against both U87 and U251 cell lines but had negligible cytotoxic effect on HEK-293. IC50 value of Sil was 155.14 µM for U87 and 195.93 µM for U251. …”
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Adverse Childhood Experiences and Cardiovascular Outcomes in Adult Congenital Heart Disease by David J. Harrison, MD, Rania A. Mekary, PhD, MS, MSc, Shilpa Vijayakumar, MD, Erin Lake, ScD, MS, Joseph Kay, MD, Roni M. Jacobsen, MD, Camila Londono-Obregon, MD, Elizabeth Yeung, MD, Sarah Kelly, PsyD, Ann Poteet, NP, MS, Michael J. Landzberg, MD, Molly Wallrich, RN, Amber D. Khanna, MD

“…Results: A total of 153 respondents provided complete data. Seventy-eight percent had moderate or complex ACHD. Mean ACEs score was 2.26 ± 2.4, 41 (27%) reported ≥4 ACEs. …”
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A comparison of floating catchment area parameters with applications to a dataset of clinics enrolled in a statewide child and adolescent psychiatric consultation program by Jocelyn Hunyadi, Jocelyn Hunyadi, Lara S. Savas, Kehe Zhang, Kehe Zhang, Jeanette E. Deason, Ryan Ramphul, Melissa F. Peskin, Erica L. Frost, Cici Bauer, Cici Bauer

“…Using the 2SFCA method, we further compared accessibility patterns across two kernel density distance decay functions for 10 catchment area specifications.ResultsAs expected, spatial accessibility measures, such as the spatial accessibility ratio (SPAR), are sensitive to input parameters, particularly the catchment area. …”
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Contemporary techniques and outcomes of surgery for locally advanced renal cell carcinoma with focus on inferior vena cava thrombectomy: The value of a multidisciplinary team by Riccardo Campi, Paolo Barzaghi, Alessio Pecoraro, Maria Lucia Gallo, Damiano Stracci, Alberto Mariotti, Saverio Giancane, Simone Agostini, Vincenzo Li Marzi, Arcangelo Sebastianelli, Pietro Spatafora, Mauro Gacci, Graziano Vignolini, Francesco Sessa, Paolo Muiesan, Sergio Serni

“…Of these, 12 (37.5%) tumours were staged as cT3a, 8 (25.0%) as cT3b, 5 (15.6%) as cT3c, and 7 (21.9%) as cT4; 6 (18.8%) patients had preoperative evidence of lymph node involvement. …”
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Sex differences and rehabilitation needs after hospital discharge for COVID-19: an Italian cross-sectional study by Luca Braglia, Monica Denti, Stefania Fugazzaro, Stefania Costi, Carlotta Mainini, Monia Allisen Accogli, Ginevra Bedogni, Daniele Ghizzoni, Anna Bertolini, Otmen Esseroukh, Cecilia Gualdi, Margherita Schiavi

“…Female sex was significantly associated with worse outcomes for all symptoms.Conclusions Individuals who had moderate or severe COVID-19 may perceive persistent symptoms which may result in reduced social participation. …”
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External relationships as implementation determinants in community-engaged, equity-focused COVID-19 vaccination events by Ramey Moore, Jennifer Callaghan-Koru, Jennifer L. Vincenzo, Susan K. Patton, Marissa J. Spear, Sheldon Riklon, Eldon Alik, Alan Padilla Ramos, Stephanie Takamaru, Pearl A. McElfish, Geoffrey M. Curran, Geoffrey M. Curran

“…Barriers to implementation also existed in external relationships, but had less influence than facilitators.ConclusionsAchieving health equity in implementation science requires greater understanding of external relationships as implementation determinants. …”
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Cardiac MRI of differing ischemia and reperfusion times in a myocardial infarction pig model by David Boll, Simon Reiss, Heidi R. Cristina Schmitz, Christian Weber, Julien Thielmann, Felix Spreter, Kian Tadjalli Mehr, Diana Chiang, Markus Jäckel, Lukas Heger, Jonathan Rilinger, Dirk Westermann, Constantin von zur Mühlen, Timo Heidt, Michael Bock, Alexander Maier

“…CMR was performed at a clinical 3 T system including functional imaging, T1 and T2 mapping and late gadolinium enhancement (LGE) 2–5 h or three days post-reperfusion. …”
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Physicochemical, Volatile Compound Profile, Antioxidant, and Cytotoxic Activities of Northeastern Thai Ethnic Ready-to-Serve Food Pastes Jaew Hon and Gang Om: A Comparative Study o... by Vijitra Luang-In, Worachot Saengha, Thipphiya Karirat, Piyathida Promjamorn, Nidthaya Seephua, Apichaya Bunyatratchata, Sudathip Inchuen, Kriangsak Banlue, Sarinthorn Suwannarong, Sirithon Siriamornpun

“…Physicochemical analyses revealed that JH OEM had the highest total dissolved solids (11.57°Brix) and water activity (0.91), while GO OEM exhibited the highest pH (5.28) and lightness (L* 31.43). …”
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Bioinformatics Analysis of Diadenylate Cyclase Regulation on Cyclic Diadenosine Monophosphate Biosynthesis in Exopolysaccharide Production by <i>Leuconostoc mesenteroides</i> DRP10... by Wenna Yu, Liansheng Yu, Tengxin Li, Ziwen Wang, Renpeng Du, Wenxiang Ping

“…Lactic acid bacteria exopolysaccharides (EPS) have a variety of excellent biological functions and are widely used in the food and pharmaceutical industries. …”
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Corticostriatal maldevelopment in the R6/2 mouse model of juvenile Huntington's disease by Carlos Cepeda, Sandra M. Holley, Joshua Barry, Katerina D. Oikonomou, Vannah-Wila Yazon, Allison Peng, Deneen Argueta, Michael S. Levine

“…Indeed, structural and functional abnormalities have been observed during brain development in both humans and animal models of HD. …”
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Contribution of Human Resources for Health competence and skill mix on compliance with healthcare quality standards among Primary Healthcare Facilities in Tanzania: evidence from d... by Syabo M. Mwaisengela, Patricia A. Materu, Chrisogone J. German, Issa I. Mmbaga, Danny J. Temba, Raymond R. Kiwesa, Martin S. Mapunda, Erick S. Kinyenje, Nathanael Sirili, Pankras W. Luoga, Simon P. Ernest, Joseph M. Burra, Joseph C. Hokororo, Godfrey Kacholi, Ntuli A. Kapologwe, Mackfallen G. Anasel, Claud J. Kumalija, Michael Habtu, Grace E. Saguti, Janeth S. Masuma, Talhiya A. Yahya, Eliudi S. Eliakimu

“…Inadequate numbers with poor skill mix compromise health system functioning that negatively affect delivery of quality healthcare services. …”
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Reproductive resilience and trade-offs: Egg component allocation under nutritional constraints in Japanese Quail by Gebrehaweria K. Reda, Sawadi F. Ndunguru, Renáta Knop, James K. Lugata, Brigitta Csernus, Gabriella Gulyás, Csaba Szabó, Ádám Z. Lendvai, Levente Czeglédi

“…In contrast, moderate restriction (DR20) and unpredictable feeding (UNPR) had no effect on any of the egg traits. These findings suggest that quails strategically allocate resources among egg components under dietary constraints, indicating potential trade-offs in reproductive investment. …”
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Psychometric properties and meaningful change thresholds for the QOL-E instrument in patients with myelodysplastic neoplasms by Esther Natalie Oliva, Shien Guo, Jennifer Lord-Bessen, Aylin Yucel, Roberto Latagliata, Massimo Breccia, Giuseppe A. Palumbo, Grazia Sanpaolo, Marta Riva, Valeria Santini, Uwe Platzbecker, Guillermo Garcia-Manero, Pierre Fenaux, Christopher G. Pelligra

“…The QOL-E domains/summary scores, except for QOL-SEX, had an adequate ability to detect change from baseline to Week 24. …”
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Identification and Expression Analysis of the Phospholipase D Gene Family in Rice by Huasheng CAO, Tang LI, Liang XIONG, Fujun WANG, Shuguang LI, Haiyong GU, Gao HE, Shihu LIANG, Wenyong LUO

“…【Result】The rice PLD gene family had 17 members with amino acid numbers ranging from 512 to 1115 and relative molecular weights ranging from 57.19 to 123.82 kD; The isoelectric points of these proteins were between 5.60 and 11.23. …”
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