Evaluation of the Immunostimulant Effect of Microvesicles of <i>Lactobacillus acidophilus</i> Isolated from Wild Rats by Pamela I. Pérez-Martínez, Viridiana Gutiérrez-Espinosa, Christian Ávalos-Gómez, Mireya De la Garza-Amaya, Alejandro Vargas-Ruíz, Rosa I. Higuera-Piedrahita, Ernesto Marín-Flamand, Cristal D. Lonngi-Sosa, Francisco R. González-Díaz, Hugo Ramírez-Álvarez, Cynthia González-Ruíz

“…It is capable of releasing membrane microvesicles (MVs), whose primary functions include carrying and transmitting antigens to host tissues and modulating host defense responses. …”
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Unilateral renal agenesis in greater rhea (Rhea americana Linnaeus, 1758) reared under human care in the potiguar semiarid, Brazil by Ana Caroline Freitas Caetano de Sousa, João Augusto Rodrigues Alves Diniz, Igor Renno Guimarães Lopes, Carlos Eduardo Vale Rebouças, Jael Soares Batista, Juliana Fortes Vilarinho Braga, Moacir Franco de Oliveira

“…Analysis of the coelomic cavity showed the absence of the left kidney and an increase in the volume of the left ureter. The right kidney had normal topography and anatomical structures. …”
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Raffinose-metabolizing bacteria impair radiation-associated hematopoietic recovery via the bile acid/FXR/NF-κB signaling pathway by Yang Jiao, Jiawei Ren, Shichang Xie, Nan Yuan, Jiaqi Shen, Huafang Yin, Jian Wang, Hongjuan Guo, Jianping Cao, Xin Wang, Depei Wu, Zhemin Zhou, Xiaofei Qi

“…Therapeutic FXR inhibition via ursodeoxycholic acid (UDCA) had been shown to be a viable method for rescuing RAHR. …”
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Association of a pace of aging epigenetic clock with rate of cognitive decline in the Framingham Heart Study Offspring Cohort by Micah J. Savin, Haoyang Wang, Heming Pei, Allison E. Aiello, Stephanie Assuras, Avshalom Caspi, Terrie E. Moffitt, Peter A. Muenning, Calen P. Ryan, Baoyi Shi, Yaakov Stern, Karen Sugden, Linda Valeri, Daniel W. Belsky

“…RESULTS Participants with faster DunedinPACE had poorer cognitive functioning at baseline and experienced more rapid cognitive decline over follow‐up. …”
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AAV-shDUX4 provides short-term benefits but limited long-term efficacy in a DUX4 mouse model of FSHD by S. Sohn, S. Reid, M. Bowen, C. Hudon, E. Corbex, B. Morel, C. Hourde, V. Mariot, J. Dumonceaux

“…However, by 10 months post-treatment, the therapeutic effects had substantially diminished, with most pathological markers remaining uncorrected and no sustained improvement in muscle force. …”
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Unilateral renal agenesis in greater rhea (Rhea americana Linnaeus, 1758) reared under human care in the potiguar semiarid, Brazil by Ana Caroline Freitas Caetano de Sousa, João Augusto Rodrigues Alves Diniz, Igor Renno Guimarães Lopes, Carlos Eduardo Vale Rebouças, Jael Soares Batista, Juliana Fortes Vilarinho Braga, Moacir Franco de Oliveira

“…Analysis of the coelomic cavity showed the absence of the left kidney and an increase in the volume of the left ureter. The right kidney had normal topography and anatomical structures. …”
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Arene Ruthenium Complexes Specifically Inducing Apoptosis in Breast Cancer Cells by Adriana Grozav, Thomas Cheminel, Ancuta Jurj, Oana Zanoaga, Lajos Raduly, Cornelia Braicu, Ioana Berindan-Neagoe, Ovidiu Crisan, Luiza Gaina, Bruno Therrien

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AMPK phosphosite profiling by label-free mass spectrometry reveals a multitude of mTORC1-regulated substrates by William J. Smiles, Ashley J. Ovens, Dingyi Yu, Naomi X. Y. Ling, Andrea C. Poblete Goycoolea, Kaitlin R. Morrison, Emmanuel O. Murphy, Astrid Glaser, Sophie F. Monks O’Byrne, Scott Taylor, Alistair M. Chalk, Carl R. Walkley, Luke M. McAloon, John W. Scott, Bruce E. Kemp, Ashfaqul Hoque, Christopher G. Langendorf, Janni Petersen, Sandra Galic, Jonathan S. Oakhill

“…Whether AMPK contains other functional mTORC1 substrates is unknown. Using mass spectrometry, we generated precise stoichiometry profiles of phosphorylation sites across all twelve AMPK complexes expressed in proliferating human cells and identified seven sites displaying sensitivity to pharmacological mTORC1 inhibition. …”
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Comprehension of acoustically degraded emotional prosody in Alzheimer’s disease and primary progressive aphasia by Jessica Jiang, Jeremy C. S. Johnson, Maï-Carmen Requena-Komuro, Elia Benhamou, Harri Sivasathiaseelan, Anthipa Chokesuwattanaskul, Annabel Nelson, Ross Nortley, Rimona S. Weil, Anna Volkmer, Charles R. Marshall, Doris-Eva Bamiou, Jason D. Warren, Chris J. D. Hardy

“…Participants listened to speech stimuli conveying three emotions in clear and noise-vocoded forms and had to identify the emotion being conveyed. We then conducted correlation analyses between task performance and measures of socio-emotional functioning. …”
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Gut microbial composition associated with risk of premature aging in women with Yin-deficiency constitution by Yingying Zhai, Yingying Zhai, Jing Li, Jing Li, Yanqi Cao, Yanqi Cao, Yufei Li, Yufei Li, Xuejie Bao, Xuejie Bao, Jinfeng Liang, Jinfeng Liang, Qi Liu, Qi Liu, Yifan Xia, Ruoxi Yu

“…Bilophila, Eubacterium, and Aeromonas were the most significant indicators influencing the YinDC premature aging. The YinDC group had the most functional gene pathways associated with the metabolism.ConclusionOur study demonstrated that the gut microbiota was associated with premature aging in women with YinDC, potentially providing preliminary evidence and guidance for personalized anti-aging strategies.…”
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Plant-microbe interactions influence plant performance via boosting beneficial root-endophytic bacteria by Sai Guo, Rubin Pan, Yan Zhang, Quanwei Gu, Qirong Shen, Jian Yang, Luqi Huang, Zongzhuan Shen, Rong Li

“…We found that medicinal plants with different growth status had distinct root-endophytic bacterial communities. …”
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Urbanization leads to asynchronous homogenization of soil microbial communities across biomes by Bangxiao Zheng, Nan Hui, Ari Jumpponen, Changyi Lu, Richard Pouyat, Katalin Szlavecz, David A. Wardle, Ian Yesilonis, Heikki Setälä, D. Johan Kotze

“…Despite these asynchronous responses—bacteria adjusting and homogenizing more than fungi—overlapping functional traits between bacteria and fungi help maintain functional resilience in urban ecosystems.…”
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Platelet-derived microparticles adoptively transfer integrin β3 to promote antitumor effect of tumor-infiltrating T cells by Mimi Zhou, Yali Feng, Xiaoli Zhang, Jianguo Chen, Naijuan Yao, Shan Fu, Tianzhi Ni, Yi Chen, Fei Xie, Sahasrabda Roy, Jinfeng Liu, Yuan Yang, Yingli He, Yingren Zhao, Nan Yang

“…Additionally, integrin β3 functioned as a positive immunomodulatory molecule to facilitate T-cell infiltration and T helper 1-type immune response in vitro. …”
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Inhibitory Effect of Hemin-Polymer System Against <i>Escherichia coli</i> and <i>Staphylococcus aureus</i> by O. A. Gruznova, D. V. Gruznov, N. I. Popov, G. Sh. Shcherbakova, E. N. Shuteeva, A. V. Lobanov, P. M. Tyubaeva, I. A. Varyan, A. A. Olkhov

“…The variation of hemin content in PHB affects its structural and functional properties. PHB fibers containing 5 % hemin inhibit the growth of gram-negative and gram-positive bacteria — E. coli and S. aureus. …”
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The epididymal microenvironment in Akodon cursor (Muridae, Sigmodontinae, Akodontini): The lifetime of spermatozoa from production to maturation by Tatiana Prata Menezes, Fernanda Carolina Ribeiro Dias, Nara Clara Lazaroni e Merchid, Camila Folly Batista, Camilo Jose Ramirez-Lopez, Arabela Guedes de Azevedo Viana, Renner Philipe Rodrigues Carvalho, Adrielli Ribeiro Araújo, José Lino-Neto, Gisele Lessa, Arlindo A. Moura, Mariana Machado-Neves

“…The epididymides were processed for histological, functional, and proteomic analyses, besides sperm quality evaluation. …”
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Grower and operational characteristics of US passion fruit farmers by Benedict C. Posadas, Eric T. Stafne, Trent Blare, Laura Downey, Joshua Anderson, Jonathan Crane, Romina Gazis, Ben Faber, Dara G. Stockton, Daniel Carrillo, J. Pablo Morales-Payan, Manjul Dutt, Alan Chambers, Dario Chavez

“…In the United States and its territories, passion fruit production has increased steadily since the 2002 USDA agriculture census; however, little is known about the reported production areas and how the industry functions. This report details the results of a survey conducted in 2022 of passion fruit producers in the United States, including Puerto Rico and Hawaii. …”
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Landscape of antisense genes in the human genome and identification of new human hepatic antisense RNAs by long-read sequencing by Juan Jose Rojo-Carrillo, Pedro Garrido-Rodríguez, Maria Llamas-López, Rosa Cifuentes-Riquelme, Jose Padilla, Bruno Ramos-Molina, Maria Luisa Lozano, Belen de la Morena-Barrio, Maria Eugenia de la Morena-Barrio, Javier Corral

“…Abstract Background Protein-coding genes have been considered the functional part of the genome, although they represent only 2% of the genome. …”
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The Role of Physical Activity in Managing ADHD Symptoms in Children and Adolescents – Review of Current Literature by Barbara Chojnacka, Aleksandra Ożga, Julia Wątor, Agnieszka Woźniacka, Jerzy Krzeszowiak, Barbara Boba, Tomasz Pulanecki, Alicja Podolska, Sylwia Bryksy, Patrycja Kolano

“…Conclusions: This review’s findings show that physical activity interventions benefit ADHD symptoms and executive functions in children and adolescents. Results of the studies showed that physical activity, especially organized closed-skill activities like running and aerobic training, enhanced the core ADHD symptoms (impulsivity, attention dysregulation, hyperactivity) the most, while open-skill activities that require real-time adaptation to environmental changes, had some effect on inhibitory control. …”
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Phage pAEv1: A potential biocontrol agent against Aeromonas veronii infections by Tongping Zhang, Sifan Jiang, Rongsi Dai, Ying Zhou, Su Long, Mingwang He, Boyang Zhou, Tao Tang, Linlin Yang, Weiming Zhong, Wenbin Xiao, YanJiao Fu, Jiajing Guo, Zhipeng Gao

“…Additionally, in vivo experiments demonstrated that grass carp treated with pAEv1 had an 80% survival rate after 7 days of exposure to a double minimum lethal dose (MLD) of the bacterium.…”
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Return to Work After Ischemic Stroke in Young Adults: A Multicenter Cohort Study, Systematic Review, and Meta‐Analysis by Gabriel Yi Ren Kwok, Nicole Yeong, Michelle Law, Zi Lun Kang, Arjun Achar, Xin Yuan Lim, Megan B. J. Ng, Yao‐Hao Teo, Sarah M. L. Tan, Jamie S. Y. Ho, Maznah Marmin, Fadhlina Hassan, Magdalene L. J. Chia, Lily Y. H. Wong, Ching‐Hui Sia, Vijay K. Sharma, Leonard L. L. Yeo, Aftab Ahmad, Benjamin Y. Q. Tan

“…In this multicenter cohort, 68.8% (249/362) of young patients with ischemic stroke returned to work, while 87.8% (318/362) achieved functional recovery. Multivariable logistic regression showed that patients with large‐artery atherosclerosis pathogenesis, diabetes, higher admission National Institutes of Health Stroke Scale scores, and higher 90‐day modified Rankin Scale had significantly lower odds of RTW. …”
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