Early results of primary total hip arthroplasty performed in young adults at a regional Saudi-Arabian orthopedics center: a prospective observational study by Walid M. Al-Shaer, Ali H. Al-Yami, Mokhtar Ahmed Al-Sayed, Ali Mohammed Al-Zaidan, Emad Ruddah Al-Sufyani, Ahmed A. Khalifa, Raad M. M. Al-Thaqafi, Abdulmohsen H. Al-Hamyani, Mohammed M. Al-Subaie

“…Our results showed improved functional outcomes and a return to pre-disease daily activities in most patients, with considerably lower complication incidence.…”
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Activated/Cycling Treg Deficiency and Mitochondrial Alterations in Immunological Non-Responders to Antiretroviral Therapy by Konstantin Shmagel, Evgeniya Saidakova, Larisa Korolevskaya, Violetta Vlasova, Souheil-Antoine Younes

“…Conclusions: The complex Treg dysregulation in immunological non-responders involves quantitative and functional alterations, including a Treg deficiency within activated/cycling naive and central memory CD4+ T-cells, impaired mitochondrial fitness of activated/cycling memory Tregs, and functional disorders of the parent conventional T-lymphocytes. …”
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Integration of single-cell sequencing and drug sensitivity profiling reveals an 11-gene prognostic model for liver cancer by Qunfang Zhou, Jingqiang Wu, Jiaxin Bei, Zixuan Zhai, Xiuzhen Chen, Wei Liang, Jing Meng, Mingyu Liu

“…We constructed and validated a LASSO model based on these genes in both sets and two external datasets. Functional, immune infiltration, and mutation analyses were performed on high and low-risk groups. …”
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Association of microtubule-based processes gene expression with immune microenvironment and its predictive value for drug response in oestrogen receptor-positive breast cancer by Zhenfeng Huang, Minghui Zhang, Nana Zhang, Mengyao Zeng, Yao Qian, Meng Zhu, Xiangyan Meng, Ming Shan, Guoqiang Zhang, Feng Liu

“…Transwell and cell viability assays were used to examine the biological functions of CHORDC1.ResultsTwo molecular subgroups with significantly different survival outcomes were identified. …”
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Organizational Methods of Furniture and Their Aesthetic Relationships in Interior Design by Akram Faraedon Hamaamen, Alwand Dlshad Najib

“…In the 20th century, the styles were launched from the movement and contemporary trends and were characterized by many scientific and technological events that had a direct impact on aesthetic relationships in the form of architecture and interior space and then the design of furniture and styles, most notably abstract and dismantling, and pop art. …”
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Comparison of the inflammatory biomarkers IL- 6, TNF-α, and CRP to predict the effect of nutritional therapy on mortality in medical patients at risk of malnutrition by Carla Wunderle, Elisabeth Martin, Alma Wittig, Pascal Tribolet, Thomas A. Lutz, Christina Köster-Hegmann, Zeno Stanga, Beat Mueller, Philipp Schuetz

“…Methods This is a secondary analysis of the Swiss-wide, multicenter, randomized controlled Effect of early nutritional therapy on Frailty, Functional Outcomes, and Recovery of malnourished medical inpatients Trial (EFFORT) trial comparing individualized nutritional support with usual care nutrition in medical inpatients. …”
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The biocontrol effects and mechanisms of mycoparasitic Alternaria alternata against Chinese rose powdery mildew by Yanping Tang, Yanping Tang, Ruotian Gao, Ruotian Gao, Changle Ma, Jin Wang, Jing Li, Jing Li

“…A total of 15 GH18 family genes were mined in KMR13, and a total of 10 chitinase genes were detected to be expressed in the transcriptome under spore induction, 5 genes were consistently up-regulated for expression after induction, and 5 genes had the highest expression at 24h of induction. …”
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Synthesis and Application of Fe₃O₄–ZrO₂ Magnetic Nanoparticles for Fluoride Adsorption from Water by Israel Águila-Martínez, José Antonio Pérez-Tavares, Efrén González-Aguiñaga, Pablo Eduardo Cardoso-Avila, Héctor Pérez Ladrón de Guevara, Rita Patakfalvi

“…FTIR analysis confirmed the presence of Fe₃O₄ and ZrO₂ functional groups, while XRD showed that increased Zr content led to a dominant amorphous phase. …”
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AlphaMissense Predictions and ClinVar Annotations: A Deep Learning Approach to Uveal Melanoma by David J. Taylor Gonzalez, MD, Mak B. Djulbegovic, MD, MSc, Meghan Sharma, MD, MPH, Michael Antonietti, BS, Colin K. Kim, BS, Vladimir N. Uversky, PhD, DSc, Carol L. Karp, MD, Carol L. Shields, MD, Matthew W. Wilson, MD

“…We explore the use of a novel deep learning tool to assess the functional impact of genetic mutations in UM. Design: A cross-sectional bioinformatics exploratory data analysis of genetic mutations from UM cases. …”
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Investigation on the interaction force measurement between bubble and particle in flotation based on resistance strain cantilever beam by Xibing REN, Lijuan SUN, Qinshan LIU, Yulong CHENG, Xiahui GUI, Yaowen XING

“…Flotation is an interfacial separation technique that achieves selective separation of valuable minerals from gangue based on differences in particle surface hydrophobicity. Its core functional unit is bubble- particle mineralization. …”
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Acceptability of veggie bread among Lebanese adults by Asma Chanbour, Hussein F. Hassan, Dima Kreidieh, Salma Khazaal, Tareq Osaili, Tareq Osaili, Khaled El Omari, Khaled El Omari, Nada El Darra

“…Incorporating vegetables as functional ingredients has gained interest in enhancing its nutritional profile. …”
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Longitudinal Evaluation of Vitamin D, Parathyroid Hormone, Antimicrobial Peptides, and Immunomodulatory Genes in Hospitalized Foals by Ahmed M. Kamr, Celine Bartish, Jamie Summers, Julia Horton, Laura D. Hostnik, Kindra Orr, Nimet Browne, Katarzyna A. Dembek, Caroline Saliba, Diego E. Gomez, Ramiro E. Toribio

“…Conclusions and Clinical Importance Decreased vitamin D metabolite concentrations and decreased antimicrobial peptide concentrations suggest that vitamin D has important immunomodulatory functions in newborn foals.…”
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miR‐32533 Reduces Cognitive Impairment and Amyloid‐β Overload by Targeting CREB5‐Mediated Signaling Pathways in Alzheimer's Disease by Li Zeng, Zhongdi Cai, Jianghong Liu, Kaiyue Zhao, Furu Liang, Ting Sun, Zhuorong Li, Rui Liu

“…Bioinformatics and confirmatory experiments revealed that miR‐32533 had a novel 23‐base sequence with minimal coding potential, functioning within the Drosha ribonuclease III (Drosha)/Dicer 1, ribonuclease III (Dicer)‐dependent canonical pathway and identifiable via northern blot. miR‐32533 was abundantly brain‐distributed and downregulated in diverse AD‐related models, including APP/PS1 and five familial AD (5×FAD) mouse brains and AD patient plasma. …”
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Biosynthesis of selenium nanoparticles from Dahlia pinnata tuberous roots with antibacterial, antidiabetic, and erythrocyte membrane protective activities by Alsayed E. Mekky, Abdullah M. Abdo, Muhammed I. Haggag, Mohammed H. Elhaw, Mostafa M. Kadry, Sameh M. Ghanem, Mokhtar M. Salama, Amal M. Soliman, Nashaat N. Mahmoud

“…For 15 multidrug-resistant (MDR, 21.4%) isolates, SeNPs had MICs of 25–50 µg/ml (mean: 35 ± 12 µg/ml) and MBCs of 50–100 µg/ml (mean: 76.6 ± 26 µg/ml). …”
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Effect of alternating salinity stress on the gut microbiota of razor clam Sinonovacula constricta by Yi Yuan, Qunqun Jiang, Qinggang Xue, Qinggang Xue, Zhihua Lin, Zhihua Lin, Wenfang Dai, Wenfang Dai

“…The salinity stress, hours post stress and their interaction had significant impact on the gut microbiota, which contributed 4.5%, 9.5% and 6.0%, respectively, to the variance in the gut communities. …”
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Integrated Transcriptomic and Metabolomic Analysis Reveals Nitrogen-Mediated Delay of Premature Leaf Senescence in Red Raspberry Leaves by Qiang Huo, Feiyang Chang, Peng Jia, Ziqian Fu, Jiaqi Zhao, Yiwen Gao, Haoan Luan, Ying Wang, Qinglong Dong, Guohui Qi, Xuemei Zhang

“…Results showed that T150 plants had 8.34 cm greater height and 1.45 cm greater ground diameter than CK. …”
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Immunomodulatory and anticancer effects of moringa polyherbal infusions: potentials for preventive and therapeutic use by Wamidh H. Talib, Wamidh H. Talib, Hadeel Shaher Al Junaidi, Heba K. Alshaeri, Moudi M. Alasmari, Moudi M. Alasmari, Rawan W. Hadi, Ahmad Riyad Alsayed, Douglas Law

“…In contrast, uncombined Moringa had the lowest activity on the tested cell lines, with an IC50 greater than 6 mg/ml. …”
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Comparison of the efficacy of one-stage revision surgery guided by precise pathogen diagnosis and conventional two-stage revision for chronic knee periprosthetic joint infection by Zhengwei Xiao, Jinyuan Zeng, Zeyu Zhang, Baijian Wu, Zihao Hong, Yufeng Guo, Chengguo Huang, Zida Huang, Zhaoyang Wu, Wenming Zhang, Xinyu Fang, Wenbo Li

“…Both the one-stage and two-stage revision groups had 3 cases of reinfection each, with no statistically significant difference in success rates between the groups (P > 0.999). …”
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Evaluating the efficiency of emergency operation centers during pandemics: a cross-sectional study with operational managers in Iran by Majid Sartipi, Majid Sartipi, Asiye Aminafshar, Asiye Aminafshar, Abdolrazzagh Pakzad, Mohammadreza Shafiei, Hojjat Farahmandnia, Asghar Tavan

“…A significant relationship was found between past crisis experience and the scores of all extracted components. Individuals who had previously been involved in crises scored higher. …”
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Impacts of Legacy and Contemporary Nitrogen Inputs on N2O and CO2 Emissions in Miscanthus and Maize Cultivated Soils by Jaejin Lee, Paul Villanueva, Kate Glanville, Andy Vanloocke, Wendy H. Yang, Angela Kent, Marshall McDaniel, Steven J. Hall, Adina Howe

“…However, the relative importance of contemporary and legacy effects and how that could vary by crop functional types is poorly understood. Considering its rhizomatous roots and perennial growth, we hypothesized that Miscanthus × giganteus (M×g) would be more sensitive to legacy N fertilization and the historical context of its environment than an annual crop like maize. …”
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