Differential roles of NaV1.2 and NaV1.6 in neocortical pyramidal cell excitability by Joshua D Garcia, Chenyu Wang, Ryan PD Alexander, Emmie Banks, Timothy Fenton, Jean-Marc DeKeyser, Tatiana V Abramova, Alfred L George Jr, Roy Ben-Shalom, David H Hackos, Kevin J Bender

“…Mature neocortical pyramidal cells functionally express two sodium channel (NaV) isoforms: NaV1.2 and NaV1.6. …”
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Effect of purpose-directed acupuncture on the pharyngeal phase in stroke patients with dysphagia based on surface electromyography: a randomized controlled trial by Yan-Qiang Qin, Ying-Chun Sun, Xian-Kuan Cheng, Hai-Jiang Yao, Shao-Hong Li, Zheng-Fan Yang, Tao Zheng, Da-Peng Li, Ling-Yong Xiao

“…After treatment, patients’ Functional Oral Intake Scale (FOIS) scores, Standardized Swallowing Assessment (SSA) scores, and surface electromyography of swallowing muscles were assessed.ResultsThe study included a total of 58 subjects, with 29 in each treatment group and control group. …”
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Impact of Vegetal Protein on the Physicochemical and Microstructural Properties of Microencapsulated Mexican Red Pitaya (<i>Stenocereus thurberi</i>) Juice by David Neder-Suárez, Carmen Oralia Meléndez-Pizarro, Esther Pérez-Carrillo, Jesús Alberto Vázquez-Rodríguez, María del Cielo Valdez-Cárdenas, Martha Graciela Ruiz-Gutiérrez, Carlos Abel Amaya-Guerra, Francisco Paraguay-Delgado, Armando Quintero-Ramos

“…Overall, plant proteins are promising alternatives to traditional carriers, offering improved stability and functionality in encapsulated products.…”
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The responses of HNSCC patients to immunotherapy are shown by two novel co-expression patterns by Narmeen Daher-Ghanem, Shay Sharon, Derrick Tao, Zhaoyu Sun, Wesley Rosales, Venkatesh Rajamanickam, Ryan Meng, Lakhvir Kaur, Brady Bernard, Brian Piening, Marcus Couey, Michael J. Gough, Nataly Kravchenko-Balasha

“…External validation in two different RNA-seq cohorts reproduced the two phenotypes and verified that patients possessing both signatures had significantly prolonged overall survival following PD-1/PD-L1 therapy. …”
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Patients’ perceptions on non‐specific effects of acupuncture: Qualitative comparison between responders and non‐responders by Robin S.T. Ho, Fai Fai Ho, Jon Adams, Holger Cramer, Brenda Leung, Lesley Ward, Yan Zhang, Vincent C.H. Chung

“…Themes emerging outside of this model were purposefully explored. Results: Responders had a more trusting relationship with acupuncturist in response to their expression of empathy. …”
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Targeted dual biologic therapy for erythroderma of unknown etiology guided by high-parameter peripheral blood immunophenotyping by Hannah L. Cornman, Martin P. Alphonse, Arbor Dykema, Alexander L. Kollhoff, Kevin K. Lee, Jaya Manjunath, Emily Z Ma, Varsha Parthasarathy, Junwen Deng, Thomas Pritchard, Anusha Kambala, Melika Marani, Kayla A. Parr, Javid P. Mohammed, Madan M. Kwatra, Jay H. Bream, Won Jin Ho, Shawn G. Kwatra

“…We found that the index patient had a novel form of erythroderma characterized by increased interleukin (IL)-13- and IL-17-producing γVδ2 T cells, basophils, and activated platelets. …”
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Structural characterization, biological activities, and rheological behavior of an exopolysaccharide from tea-bacteria Herbaspirillum sp. S-1 by Xuedong Chen, Guoqiang Chen, Mengjiao Li, Zixiang Liu, Wenxue Dai, Fan Wang, Haibo Zhang, Fei Liu, Youshuang Zhu

“…HS and S-1 exhibited anti-proliferative effects on HT-29 and BEL-7402 cells, whereas S-1 had higher anti-proliferative activity than HS. …”
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Knockdown of LncRNA H19 inhibits vascularization and endochondral ossification via the MiRNA-21a-5p-Smad7/p-Smad2/3 pathway in fracture repair by Qiuyue Sun, Chen Zhang, Bowen Chen, Junyi Liao, Aowen Bao, Chen Zhao, Hong Chen, Dawei He, Wei Huang, Guangming Dai

“…Importantly, H19 inhibition had no impact on the formation of the cartilaginous callus, indicating its specific role in vascularization and ossification. …”
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Soil and Root Responses in Hazelnut Rhizosphere to Inoculate Rhizobacteria Immobilized via JetCutter Technology by Solange V. Benítez, Rocío Carrasco, Antonio Roldán, Fuensanta Caravaca, Manuel Campoy, Joaquín Cofré, José Ortiz, Juan D. Giraldo, Mauricio Schoebitz

“…Conclusions: Immobilized Gram-negative PGPR strains enhanced root development and soil biochemical activity in hazelnuts, whereas <i>B. safensis</i> enhanced photosynthesis but had minimal impact on soil properties. These results highlight functional differences and support the use of PGPR immobilization to promote early plant establishment.…”
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From waste to value: protein hydrolysates from byproducts of the Argentine hake (Merluccius hubbsi) processing using endogenous enzymes and Alcalase® 2.4L by Clara Liebana, Nair de los Ángeles Pereira, Analia Fernández-Gimenez, Maria Florencia Fangio

“…Waste from Argentine hake (Merluccius hubbsi) could enhance its functional and antioxidant properties through hydrolysis, releasing peptides with bioactive properties. …”
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Identification and expression characterization of apple β-tubulin gene family in apple by HUANG Huiling, WANG Yanxiang, WANG Yue, NING Qinqin, LI Ming, HAO Pengbo, CONG Liu, BAI Tuanhui, SHI Jiangli, JIAO Jian, WANG Miaomiao, LIU Yu, ZHAO Yujie, WAN Ran, SHEN Yawen, ZHANG Hengtao, ZHANG Kunxi, ZHENG Xianbo

“…The results will provide a theoretical basis for further research on the regulatory functions of apple dwarfing by β-tubulin genes.…”
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Genetic heterogeneity in patients with enlarged vestibular aqueduct and Pendred syndrome by Marek Sklenar, Silvia Borecka, Lukas Varga, Emanuele Bernardinelli, Juraj Stanik, Martina Skopkova, Miroslav Sabo, Diana Ugorova, Silvia Dossena, Daniela Gasperikova

“…Fifteen variants in the SLC26A4 gene were identified in total, three of which are novel. The functional characterization of the novel variants and variants which were not yet functionally characterized confirmed the pathogenic potential of five out of six tested variants (p.G139R, p.M147I, p.Y530S, p.D754Ifs*5, and p.F161I). …”
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Salivary lactoferrin levels in Down Syndrome: a case-control study by Desireé Antequera, Lucía Sande, Eliane García Mato, Deborah Romualdi, Laura Carrero, Cristina Municio, Pedro Diz, Eva Carro

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PD-1 is expressed in cytotoxic granules of NK cells and rapidly mobilized to the cell membrane following recognition of tumor cells by Cecilia Pesini, Sandra Hidalgo, Maykel A. Arias, Llipsy Santiago, Carlota Calvo, Maitane Ocariz-Díez, Dolores Isla, Pilar M. Lanuza, M José Agustín, Eva M Galvez, Ariel Ramírez-Labrada, Julián Pardo

“…We provide novel key findings on the mechanism involved in the regulation of PD-1 expression on NK cell membrane and its functional consequences for the elimination of cancer cells. …”
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Altered diversity and composition of gut microbiota in Korean children with food allergy by Minyoung Jung, Ji Young Lee, Sukyung Kim, Jeongmin Song, Sehun Jang, Sanghee Shin, Min Hee Lee, Mi Jin Kim, Jiwon Kim, Han Byul Lee, Yeonghee Kim, Kangmo Ahn, Minji Kim, Jihyun Kim

“…Bacterial species richness, intracommunity diversity, and intergroup dissimilarity were evaluated. Functional profiles were predicted using Phylogenetic Investigation of Communities by Reconstruction of Unobserved States (PICRUSt) and the Minimal Set of Pathways (MinPath) algorithm. …”
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Association between dietary antioxidants, serum albumin/globulin ratio and quality of life in esophageal squamous cell carcinoma patients: a 7-year follow-up study by Juwei Zhang, Jinsong Zhou, Siting Chen, Yue Huang, Zheng Lin, Yuan Deng, Minglian Qiu, Zhisheng Xiang, Zhijian Hu, Zhijian Hu

“…The results indicate that compared to the low DAI-AGR group, the high DAI-AGR group had a lower rate of deterioration events, and the time to deterioration in emotional functioning (p=0.014), dysphagia (p=0.042), and speech problems (p=0.023) were significantly delayed. …”
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Demonstration of therapeutic effect of plasma-synthesized polypyrrole/iodine biopolymer in rhesus monkey with complete spinal cord section by Camilo Ríos, Hermelinda Salgado-Ceballos, Israel Grijalva, Axayacatl Morales-Guadarrama, Araceli Diaz-Ruiz, Roberto Olayo, Juan Morales-Corona, María G. Olayo, Guillermo J. Cruz, Rodrigo Mondragón-Lozano, Laura Alvarez-Mejia, Carlos Orozco-Barrios, Stephanie Sánchez-Torres, Omar Fabela-Sánchez, Angélica Coyoy-Salgado, Braulio Hernández-Godínez, Alejandra Ibáñez-Contreras, Marisela Mendez-Armenta

“…At the end of the follow-up, a thinner glial scar in the injured spinal cord was observed in the experimental NHP as well as regenerative nerve processes (NeuN and β-III tubulin expression), while control NHP had a marked glial scar, large cysts and less nerve tissue at the injured zone. …”
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Evaluating neutrophil-lymphocyte ratio, systemic immune-inflammation index, and systemic inflammation response index for diagnosing and predicting progression in diabetic retinopat... by Yi Gong, Linni Wang, Qingbo Li, Manqiao Wang, Rong Luan, Fei Gao, Liying Hu, Chen Chen, Juping Liu, Yan Shao, Xiaorong Li

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Study on the Anti-Photocorrosion Mechanism of Novel Self-Assembled Spherical Cu₂O/FePO₄ Z-Scheme Heterojunctions by Kuo Zhang, Xiufei Zhao, Hang Qian, Lihong Chen, Biyu Wu, Xiao Yang, Haonan Zou, Yujiao Hu, Feng Chen, Borong Liao, Hu Zhou, Lei Zhang, Tianyi Ma, Yusheng Zhang

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ER membrane receptor FgGET2 plays critical roles in hyphal growth, asexual development, stress responses, and pathogenicity of Fusarium graminearum by Caihong Liu, Lu Lei, Jing Zhu, Mi Zhang, Ziyi Zhang, Shijing Peng, Jie Tang, Lirun Chen, Qing Chen, Li Kong, Yunfeng Jiang, Guoyue Chen, Qiantao Jiang, Yazhou Zhang, Qiang Xu, Youliang Zheng, Karl-Heinz Kogel, Yuming Wei, Pengfei Qi

“…Deleting FgGET2 in F. graminearum had detrimental effects on vegetative growth polarity, vacuolar morphology, and conidial production, morphology, and germination. …”
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