A theory-based analysis of the implementation of online asynchronous telemedicine platforms into primary care practices using Normalisation Process Theory by Cara Leighton, Natalie Joseph-Williams, Annavittoria Porter, Adrian Edwards, Alison Cooper

“…Reflexive action through large- and small-scale studies had allowed improvements to be made, but poor response rates inhibit this. …”
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Detection and tissue-localization of Himetobi P virus in Nilaparvata lugens (Stål) by HUANG Yuji, CHEN Bin, ZHANG Chuanxi

“…Real-time PCR and immunohistochemical staining results demonstrated that the post part of the BPH midgut had the highest HiPV concentration, followed by Malpighian tubules. …”
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THE EFFECT OF TOCILIZUMAB ON THE CONDITION OF BONE TISSUE OF PATIENTS WITH SYSTEMATIC JUVENILE IDIOPATIC ARTHRITIS: RESULTS OF A SERIES OF CASES RETROSPECTIVE STUDY by M. S. Shingarova, E. I. Alexeeva, T. M. Bzarova, R. V. Denisova, S. I. Valieva, M. L. Travina, K. B. Isaeva, М. А. Soloshenko, O. L. Lomakina

“…High activity of the disease has been noted with all chlidren; 23 (47%) had limitation of functional activity (score on the questionnaire CHAQ). 36 (74%) children took 0.5 mg/kg of glucocorticosteroids  per day orally, 32 (65%) — intravenously. …”
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Impact of obesity on proteomic profiles of follicular fluid-derived small extracellular vesicles: A comparison between PCOS and non-PCOS women by Qiyuan Chang, Senlan Wang, Qingyun Mai, Canquan Zhou

“…Results Proteomic profiling of sEVs revealed that the overweight/obese PCOS group had 180 upregulated and 256 downregulated proteins compared to lean counterparts. …”
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Combination of RNA-sequencing data analysis, network pharmacology, molecular docking techniques to investigate the mechanism of Prunella vulgaris L. in the treatment of non-small c... by Yanggang Dan, Yangli Jin, Jing Wang, Lu Wang, Dawei Zheng

“…The key components morin, luteolin, delphinidin, kaempferol and quercetin had good binding affinity with the core targets (AKT1, MMP9, ESR1, XDH and CYP1B1). …”
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Parietal-specific activation reveals pain from inadequate levels of altitude acclimatization/ adaptation. by Shurong Jia, Niannian Wang, Rui Su, Hailin Ma, Hao Li

“…<h4>Methods</h4>A total of 65 HA residents were recruited, all of whom had resided continuously in HA regions for a minimum duration of one month. …”
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Exploring the mechanism of platycodin D in inhibiting nasopharyngeal carcinoma based on network pharmacology combined with experimental validation by LEI Benlan, YANG Jiangping, CHEN Yanfang, HUANG Jinglun, ZHANG Xiping, MA Canfang, LIANG Gang, JIAO Aijun

“…The molecular docking results showed that platycodon D had good binding activity with the core target. …”
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Blood oxygenation state in COVID-19 patients: Unexplored role of 2,3-bisphosphoglycerate by Maria Sofia Bertilacchi, Rebecca Piccarducci, Alessandro Celi, Lorenzo Germelli, Chiara Romei, Brian J Bartholmai, Greta Barbieri, Chiara Giacomelli, Claudia Martini

“…Background: COVID-19 reduces lung functionality causing a decrease of blood oxygen levels (hypoxemia) often related to a decreased cellular oxygenation (hypoxia). …”
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The effect of depression on antiretroviral drug non-adherence among women living with HIV in Gondar health facilities, northwest Ethiopia: a prospective cohort study by Tadele Amare Zeleke, Tadesse Awoke Ayele, Zewditu Abdissa Denu, Lillian Mwanri, Telake Azale

“…Understanding depression’s role in ART is crucial for generating evidence to improve individuals’ functionality and treatment outcomes. This study aimed to examine the effects of depression on ART non-adherence among WLWHIV in Ethiopia.MethodsA prospective cohort study was conducted with data collected from 627 study participants who were on stable ART regimens at baseline, 3 months, and 6 months. …”
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Comparison of short-term clinical outcomes of intra-articular injection of micro-fragmented adipose tissue and stromal vascular fraction cells for knee osteoarthritis treatment: A... by Takuma Maeda, Satoshi Sobajima, Tomoyuki Matsumoto, Masanori Tsubosaka, Takehiko Matsushita, Hideki Iwaguro, Ryosuke Kuroda

“…Patients with KL grades I–IV varus knee OA, significant pain (VAS ≥40), and functional impairment despite conservative treatments were included. …”
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Assessment of diabetes health literacy and its predictors among diabetic older adults attending geriatric clubs, 2024 by Hany Hassan Ziady, Nadia Abd El-monem El-Zeiny, Ebtisam Mohamed Fetohy, Sarah Ali Hafez Hewi, Eman Mohamed Ahmed Hagras

“…Ethical approval was obtained, and verbal informed consent was secured from all participants.Results The study participants had a median age of 66 years (IQR: 9), with 82.2% females and 56.5% widowed. …”
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Relationship of immunogenetic and immunologic markers and their influence on disease activity and radiological progression in patients with early rheumatoid arthritis by N V Demidova

“…Activity of RA was assessed with DAS28 and functional status – with Russian version of HAQ questionnaire. …”
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NFLUENCE OF CYP4F2*3 ON RESPONSE TO CLOPIDOGREL IN PATIENTS WITH ACUTE CORONARY SYNDROME by K. B. Mirzaev, O. D. Konova, E. A. Grishina, K. A. Ryzhikova, Zh. A. Sozaeva, D. A. Andreev, M. Y. Gilyarov, D. A. Sychev

“…CYP4F2 allelic variants were detected by the method of real-time polymerase chain reaction. Platelet functional activity was evaluated by a portative aggregometer – the VerifyNow P2Y12 assay.Results. …”
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NLRP11 is required for canonical NLRP3 and non-canonical inflammasome activation during human macrophage infection with mycobacteria by Mateusz Szczerba, Akshaya Ganesh, María Luisa Gil-Marqués, Volker Briken, Marcia B. Goldberg

“…In conclusion, we show that NLRP11 functions in the non-canonical caspase-4/caspase-5 inflammasome activation pathway and the canonical NLRP3 inflammasome pathway and that NLRP11 is required for full recognition of mycobacteria by each of these pathways. …”
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Bioinformatics analysis identifies BST1 as a potential therapeutic target linked to neutrophil extracellular traps in patients with acute liver failure by Mengyu Tao, Jiwei Fu, Xiaoping Wu

“…A total of 1694 DEGs were identified, and the biological functions and signaling pathways closely related to ACLF were monocyte differentiation and immune-metabolic processes. …”
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Exploring Dynamic Mechanisms of Spatial Production and Transformational Development in Urban Villages: A Case Study of Gaopu Village in Xiamen City, China by Xiao Ming, Yin Chenyu, Li Xueping, Yang Sisheng

“…Market mechanisms, particularly the establishment of the Xinglin Industrial Zone, increased tourism while industrial upgrading enhanced the economic level of Gaopu Village and facilitated the optimization of spatial functions. In addition, the profound local culture in Gaopu Village, including historical memory, community identity, and values, had an implicit stabilizing role in the transformation, which strengthened the villagers' sense of belonging and cohesion and promoted the coordination of multiple interests and consensus formation. …”
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Hybrid decompression-based surgical strategy for treating multilevel thoracic ossification of the ligamentum flavum: a retrospective study by Cong Nie, Kaiwen Chen, Shenyan Gu, Feizhou Lyu, Jianyuan Jiang, Xinlei Xia, Chaojun Zheng

“…Furthermore, more patients undergoing en bloc laminectomy had CFL than those undergoing hybrid laminectomy (46.4% vs. 15.0%, p=0.023). …”
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Compensatory mechanisms in γδ T cell-deficient chickens following Salmonella infection by Felix Tetzlaff, Felix Tetzlaff, Ulrich Methner, Theresa von Heyl, Christian Menge, Benjamin Schusser, Benjamin Schusser, Angela Berndt

“…In later stages of the infection, the γδ T cells and their functions appear to be replaced by other cells.…”
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Correction of eating disorders in patients with oral and oropharyngeal cancer after reconstructive plastic surgery by E. A. Krasavina, E. L. Choynzonov, D. E. Kulbakain, V. A. Aleekseev

“…The use of the microvascular surgical techniques using various donor flaps creates the basis for a more complete functional recovery and expands the rehabilitation potential of patients after surgical treatment of oral and oropharyngeal cancer.…”
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Health Perceptions and Mental Well-Being: A LASI-Based Study of Depression in Indian Older Adults by Shanku Paul, Jayashree Das, Dipankaj Das, Ujjal Paul

“…Results: Older adults reporting poor self-rated health had significantly higher odds of depression (AOR = 2.47, 95% CI: 2.36–2.59), and those with average health also showed increased odds (AOR = 1.46, 95% CI: 1.42–1.50), compared to those reporting good health. …”
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