AMBRISENTAN: THE POSSIBILITY OF THE TREATMENT FOR PULMONARY ARTERIAL HYPERTENSION WITH THE SELECTIVE BLOCKADE OF THE ENDOTHELIN SYSTEM by T. V. Martynuk, S. N. Nakonechnikov, I. E. Chazova

“…In 2012 ambrisentan was approved by the Russian National Pharmacological Committee for the treatment of patients with PAH (Functional Classes II-III) at the dose of 5 mg and 10 mg PO.…”
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The positive impact of robotic‐assisted BCR TKA on post‐operative joint line restoration, lateral posterior condylar offset and standard and advanced activity in the 2011 Knee Soci... by Takao Kaneko, Kosuke Shiga, Ayakane Yamamoto, Kazuki Amemiya, Masaru Omata, Shu Yoshizawa

“…Results Pre‐operative knee scores were significantly higher in the Robot group (mean: 20.5) than in the Conventional group (mean: 16.8), while functional scores were significantly lower in the Robot group (mean: 57.7) than in the Conventional group (mean: 69.6). …”
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Partial replacement of high-fibre forages with corn silage across the lactation cycle: effects on methane emission, rumen fermentation and efficiency in dairy cows by M. Eslamizad, M. Schmicke, H. Sauerwein, B. Kuhla

“…After calving, cows with a divergent breeding value for functional herd life were equally allocated to a lactation diet containing forage (66% of DM) of either low (LCS; 31.1% DM) or high corn silage (HCS; 37.7% DM) proportion. …”
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When do the symptoms of autonomic nervous system malfunction appear in patients with Parkinson’s disease? by De Luka Silvio R., Svetel Marina, Pekmezović Tatjana, Milovanović Branislav, Kostić Vladimir S.

“…The patients who developed complete autonomic neuropathy (both sympathetic and parasympathetic) were individuals with considerable level of functional failure, more severe clinical presentation and the existing anxiety and depression. …”
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The Outcomes of Delayed Revascularization in Lower Extremity Vascular Injury: A Retrospective Cohort Study by Chai KS, Faisham WI, Wan-Sulaiman WA, Rosli MA, Mat-Saad AZ, Jusoh MH, Paiman M, Halim AS

“…A total of 83.1% of patients (n=49) had a Mangled Extremity Severity Scoring (MESS) of 7 and above. …”
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A Retrospective Analysis of the Results of Microinvasive Posterior Vitrectomy in the Surgical Treatment of Non-Full Thickness Macular Holes by Y. V. Bayborodov, K. S. Zhogolev, L. I. Balashevich, I. E. Panova, D. R. Mirsaitova

“…Purpose: to study the effectiveness of the posterior microinvasive vitrectomy in the surgical treatment of non-full thickness macular holes on the basis of the retrospective analysis of the retina changes, identified by OCT, and functional outcomes of surgical treatment.Patients and Methods. …”
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Vasoreactive testing prevalence and characteristics in patients with idiopathic pulmonary arterial hypertension by Goncharova Natalia, Kirill Lapshin, Aelita Berezina, Irina Zlobina, Anton Ryzhkov, Zhaneta Matakaeva, Elizaveta Andreeva, Olga Moiseeva

“…INTRODUCTION: The choice of treatment strategy in patients with idiopathic pulmonary arterial hypertension (IPAH)/HPAH/DPAH (Hereditary pulmonary arterial hypertension/ Drug-induced pulmonary arterial hypertension) II-III functional class (FC) (WHO) based on an acute vasoreactive testing result (VRT). …”
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Soil enzyme activities and health indicator characteristics in furrow‐irrigated and flooded rice production systems by Aziz Ahmed, Jim J. Wang, Manoch Kongchum, Dustin L. Harrell, Nutifafa Adotey, Md Ali Haider, Lewis Gaston, Changyoon Jeong

“…Despite FIR's growing adoption, its impacts on soil biological functioning and nutrient cycling remain poorly understood, limiting the ability to optimize management practices for this emerging system. …”
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Cytotoxic and Antioxidant Properties and Profile of Active Compounds in Kale and Lupine Sprouts Supplemented with γ-Polyglutamic Acid During Sprouting by Agnieszka Galanty, Paulina Kłos, Ewelina Prochownik, Paweł Paśko, Tomasz Skalski, Robert Podsiadły, Paweł Zagrodzki

“…These results provide a foundation for developing functional foods and sustainable agricultural practices.…”
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Effect of India’s flagship conditional maternity benefit scheme on utilization of maternal and child health services: evidence from a statewide evaluation study by Rupsa Banerjee, Bhanu Shanker Singh, Neha Sahrawat, Amit Mehrotra, Sumant Swain, Ram Manohar Mishra, Piush Antony, U. Aparna, B. K. Jain, Sutapa Bandyopadhyay Neogi

“…This study evaluates the functional status of the scheme, knowledge regarding the scheme and its effect on pattern of service utilization in a north Indian state. …”
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The effect of vibroacoustic therapy on the structural integrity of erythrocytes and platelets in patients with acute exogenous poisoning by M. S. Makarov, Yu. S. Goldfarb, A. V. Badalyan, A. Yu. Simonova, M. M. Potskhveriya

“…Meanwhile, in 50% of patients, platelets had a tendency to spontaneous activation and hyperactivation. …”
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MGMT epimutations and risk of incident cancer of the colon, glioblastoma multiforme, and diffuse large B cell lymphomas by Oleksii Nikolaienko, Garnet L. Anderson, Rowan T. Chlebowski, Su Yon Jung, Holly R. Harris, Stian Knappskog, Per E. Lønning

“…The study cohort was drawn from postmenopausal women, participating in the Women’s Health Initiative (WHI) study, who had not been diagnosed with either colon cancer, glioblastoma, or B-cell lymphoma prior to study entry. …”
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Effects of hepatitis B virus infection and antiviral therapy on the clinical prognosis of nasopharyngeal carcinoma by Jing‐Jin Weng, Jia‐Zhang Wei, Min Li, Jin‐Long Lu, Yang‐Da Qin, He Jiang, Shen‐Hong Qu

“…The hepatitis B surface antigen‐positive [HBsAg(+)] group had a lower CD4+ T cell count than the HBsAg(−) group (P = .048). …”
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Carotid intima thickness and elasticity combined with MHR predicting the severity of coronary artery stenosis in patients with premature coronary artery disease by Chenjing Xu, Ming Wu, Xijun Zhang, Kaikai Shen, Yanyan Guo, Jianjun Yuan, Haohui Zhu

“…Abstract Background Carotid intima thickness (CIT) and hardness coefficient (HC) are sensitive indicators of structural and functional changes in the carotid arteries in the subclinical stage of atherosclerosis. …”
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Efficacy, safety and the lymphocyte subsets changes of low‐dose IL‐2 in patients with systemic lupus erythematosus: A systematic review and meta‐analysis by Qin‐Yi Su, Jing Luo, Xin‐Miao Wang, Jing‐Kai Di, Yi‐Xin Cao, Sheng‐Xiao Zhang

“…Results After the LD‐IL‐2 treatment, 54.8% of patients had distinct clinical remission. The SRI‐4 response rates were 0.819 (95% confidence interval [CI]: 0.745–0.894), and the SELENA‐SLEDAI scores were significantly decreased (SMD = −2.109, 95% CI: [−3.271, −0.947], p < .001). …”
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Association between Val158Met polymorphism in the COMT gene with anxiety and heart rate variability in children with irritable bowel syndrome by M. O. Semen, O. L. Lychkovska, M. Ya. Tyrkus, D. V. Kaminskyy, O. P. Yelisyeyeva

“…Results. Depending on the functional COMT Val158met polymorphism, all the patients were allocated to 3 groups: 8 children with 472 GA (Val/Met) COMT genotype; 10 children with 472 AA (Met/Met) genotype; 8 children with 472 GG (Val/Val) genotype. …”
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P-4 HYPOTHERMIC OXYGENATED PERFUSION USING AN ECMO DEVICE IN LIVER TRANSPLANTATION: AN ANALYSIS OF THE FIRST 100 CASES AT A CHILEAN PUBLIC HOSPITAL by FRANCISCA MAGDALENA MARTÍNEZ VENEZIAN, Elizabeth Rivas, Valeria Galaz, Valentina Castillo, Julio Benitez, Edmundo Martinez, Rodrigo Wolff, Blanca Norero, Erwin Buckel, Rolando Rebolledo

“…Post-transplantation, key outcomes such as liver functionality, early complications, and overall survival were monitored in all patients. …”
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Predictive value of dendritic cell-related genes for prognosis and immunotherapy response in lung adenocarcinoma by Zihao Sun, Mengfei Hu, Xiaoning Huang, Minghan Song, Xiujing Chen, Jiaxin Bei, Yiguang Lin, Size Chen

“…Methods DC-related biological functions and genes were identified using single-cell RNA sequencing (scRNA-seq) and bulk RNA sequencing. …”
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Identification and Validation of Circadian Rhythm‐Related Genes Involved in Intervertebral Disc Degeneration and Analysis of Immune Cell Infiltration via Machine Learning by Yongbo Zhang, Liuyang Chen, Sheng Yang, Rui Dai, Hua Sun, Liang Zhang

“…Immune infiltration analysis revealed that the IVDD group had significantly more M0 macrophages and significantly fewer follicular helper T cells than those of the control group. …”
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CHARACTERISTICS OF THE KALLIKREIN-KININ SYSTEM IN PATIENTS WITH GLOSSALGIA by E.N. Dychko, P.L. Sribnik, A.V. Schtompel

“…Among the patients were women aged from 42 to 62 years, they had underlying chronic diseases of the nervous, digestive and cardiovascular systems. …”
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