Safety of Early Carotid Artery Stenting after Systemic Thrombolysis: A Single Center Experience by Fabrizio Sallustio, Giacomo Koch, Alessandro Rocco, Costanza Rossi, Enrico Pampana, Roberto Gandini, Alessandro Meschini, Marina Diomedi, Paolo Stanzione, Silvia Di Legge

“…After 12 months, all patients had stent patency, and the functional outcome was favourable (mRS ≤ 2) in all but 1 patient experiencing a recurrent stroke for new-onset atrial fibrillation. …”
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Comparison of large single and small multiple doses of cyclophosphamide exposure in mice during early prepubertal age on fertility outcome by Sujith Raj Salian, Akshatha Daddangadi, Dhakshanya Predheepan, Divya Deeleep Bhagat Amonkar, Riddhi Kirit Pandya, Sindhura Lakshmi Koulmane Laxminarayana, Shubhashree Uppangala, Guruprasad Kalthur, Richard A. Anderson, Satish Kumar Adiga

“…Surviving females were assessed for estrous cyclicity, ovarian follicle reserve, oocyte functional competence, and postnatal assessment of first-generation (F1) pups. …”
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Nasal polyposis: A semiquantitative morphometric histopathological study by Trivić Aleksandar, Tomanović Nada, Krejović-Trivić Sanja, Milovanović Jovica, Boričić Ivan, Jotić Ana, Folić Miljan, Ćolović-Čalovski Ivana, Miković Nikola, Tatić Zoran

“…The study comprised 77 patients with chronic rhinosinusitis and nasal polyposis (CRSwNP) that underwent functional endoscopic sinonasal surgery performed by the same surgeon. …”
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The impact of interactions between heavy metals and smoking exposures on the formation of oral microbial communities by Qiwen Zheng, Yonghua Zhang, Jia Li, Shuwei Pei, Jiangyun Liu, Lu Feng, Li Zhang, Xingrong Liu, Bin Luo, Ye Ruan, Weigang Hu, Jingping Niu, Tian Tian

“…By comparing the oral bacterial communities and functional pathways between the four groups, we found significant differences in bacterial communities and functional pathways between the groups. …”
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Porcine reproductive and respiratory syndrome virus NSP5 exploited UBE2L6 to promote viral replication via antagonising host RLRs and ISGylation by Zhenbang Zhu, Lulu Chen, Meng Zhang, Qianwen Lin, Yifan Yan, Wenqiang Wang, Wei Wen, Zhendong Zhang, Xiangdong Li

“…Within this process, ISG15-conjugating enzyme E2L6 (UBE2L6) functions as an E2 ubiquitin/ISG15-conjugating enzyme, which is crucial for the enzymatic cascades of UPS and ISGylation. …”
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Wharton’s jelly mesenchymal stromal cells derived from preterm umbilical cord reveal a hepatogenic potential by F. Timoneri, M. Lo Iacono, S. Corrao, G. Alberti, G. Amico, T. Corsello, P. G. Conaldi, Eleonora Russo, Eleonora Russo, G. La Rocca

“…A standardized liver differentiation protocol was performed, and the acquisition of the hepatic phenotype was assessed by characterization of hepatic protein expression and functional assays.ResultsWe demonstrated that pWJ-MSCs exhibited mesenchymal characteristics, acquired phenotypical and functional features of hepatocytes when induced to differentiate in a specific medium, and maintained the expression of immunomodulatory molecules.DiscussionThis study showed that even if pregnancy has been interrupted before the 22nd week, p-WJ-MSCs had the same differentiative ability as the counterpart derived from the full-term UC, that we have previously demonstrated, and can be considered a valid cellular population for liver cell therapy.…”
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Simplified above-knee amputation with short operation time and minimal blood loss for ultra-high-risk patients under nerve block and local anesthesia by Marin Mimura, MD, Yu Kagaya, MD, PhD, Hikaru Kono, MD, Toshiki Furukawa, MD, Tetsu Kojima, MD, Fumio Onishi, MD, PhD

“…We included 12 consecutive patients on whom the procedure was performed (7 with chronic limb-threatening ischemia and 5 with acute limb ischemia) while they were taking anticoagulant or antiplatelet drugs. All the patients had an American Society of Anesthesiologists physical status of class III or higher (class III: severe systemic disease with substantive functional limitations [n = 6]; class IV: severe systemic disease that is a constant threat to life [n = 6]). …”
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Can we predict neurological complications in patients with metastatic spinal tumors? by Chul Jung, Hee Tae Shin, Cho Rong Bae, Joon Hee Lee, Jin Hoon Park, Jae-Hwan Cho, Choong Guen Chee, Jae Yong Jeon

“…This study provides valuable insights for predicting 1-year functional outcomes and determining management strategies for spinal metastases.…”
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Disulfidptosis-based molecular clustering and prognostic signatures predict patient survival and the immune landscape in patients with colon cancer by Liang Wen, Yongli Ma, Jinghui Li, Dengzhuo Chen, Chengzhi Huang, Ping Wang, Suqi Wen, Gexin Wen, Jizhen Guo, Guosheng Zhang, Junjiang Wang, Xueqing Yao

“…Therefore, how disulfidptosis affects colon cancer and how it functions in the immune system are unknown. Methods Disulfidptosis-related gene (DRG) expression information was obtained from the TCGA-COAD cohort. …”
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Critical risks of haemoadsorption for COVID-19 patients and directions for future evaluations: a nationwide propensity score matched cohort study by Jan Andreas Kloka, Thomas Jasny, Oliver Old, Elina Nürenberg-Goloub, Christina Scharf, Patrick Meybohm, Alexander Supady, Kai Zacharowski, Benjamin Friedrichson

“…Two-sided probability values for group comparisons and regression models with spline functions controlling for non-linear relationships and medically relevant interaction variables were calculated. …”
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miPEP31 alleviates sepsis development by regulating Chi3l1-dependent macrophage polarization by Yu Zhou, Yuan Yuan, Xuanqi Yao, Lin Wang, Liangfang Yao, Daolin Tang, Feng Chen, Jinbao Li

“…The utilization of miPEP31 as a therapeutic intervention had a substantial impact on reducing mortality rates, mitigating organ damage, inducing macrophage polarization towards the M2 phenotype, and suppressing the inflammatory response in murine models of severe sepsis. …”
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Integration of nontarget screening and QSAR modeling to identify novel butachlor transformation products of high priority in soil and water environment by Feng Chen, Chi Wu, Lan Zhang, Liangang Mao, Lizhen Zhu, Xingang Liu

“…Finally, Ecotoxicity modeling showed certain TPs, particularly TP277, had “extreme” acute toxicity to Daphnia magna, while TP277 and TP293 posed higher chronic toxicity risks to Danio rerio than the parent compound. …”
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Detection of Myocardial Deformation Patterns and Prognostic Value of Routine Echocardiographic Parameters in Patients with Cardiac Sarcoidosis Versus Extracardiac Sarcoidosis: Syst... by Hritvik Jain, Maryam Shahzad, Muhammad Usman, Anil KC, Jagjot Singh, Jyoti Jain, Ramez M. Odat, Aman Goyal, Faizan Ahmed, Raheel Ahmed

“…This meta-analysis aims to evaluate differences in functional echocardiographic parameters between patients with CS and extracardiac sarcoidosis (ECS) to improve early recognition and management. …”
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Prognostic value of temporalis muscle thickness as a marker of sarcopenia in intracerebral hemorrhage by Waldemar Gubarev, Jan Klinke, Ulrike Voßmann, Daniel Cantré, Bijan Zendeh Zartoshti, Artem Rafaelian, Milos Arsenovic, Daniel Dubinski, Sae-Yeon Won, Florian Gessler, Thomas Freiman, Alexander Storch, Matthias Wittstock

“…It has not been conclusively clarified whether sarcopenia is predictive for the functional outcome in ICH. Determining the temporalis muscle thickness (TMT) may be helpful for estimating sarcopenia. …”
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Ligilactobacillus salivarius regulating translocation of core bacteria to enrich mouse intrinsic microbiota of heart and liver in defense of heat stress by Jiajun Yang, Jiajun Yang, Peng Shang, Peng Shang, Zongliang Liu, Jing Wang, Bo Zhang, Hao Zhang

“…Lactobacillus sp. were found in the liver but not in the heart. The heart had a lower bacterial abundance than the liver. …”
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Cognitive behavioral therapy for ADHD predominantly inattentive presentation: randomized controlled trial of two psychological treatments by Elinor Eskilsson Strålin, Lisa B. Thorell, Tobias Lundgren, Sven Bölte, Sven Bölte, Sven Bölte, Benjamin Bohman

“…Self-reported scales were used to assess outcome measures of behavioral activation, procrastination, symptoms of ADHD, depression, quality of life and functional impairment. Data were analyzed for between and within-group effects using multilevel modeling.ResultsBetween-group analysis showed that participants in the CADDI group had significantly greater improvement on the primary outcome measure of activation at post assessment (p = .045, d = 0.49). …”
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Clinical evaluation of usefulness and effectiveness of sitting-type continuous passive motion machines in patients with total knee arthroplasty: a dual-center randomized controlled... by Byung Chan Lee, Chang-Won Moon, Woo Sung Choi, Young Mo Kim, Yong Bum Joo, Da Gyo Lee, Sook Joung Lee, Eunseok Choi, Jong Hun Ji, Dong Whan Suh, Kang Hee Cho

“…Passive and active ranges of motion (ROMs), pain, lower-extremity edema, patient-reported outcomes, and functional assessments were evaluated at four time points. …”
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Association of tinnitus with obstructive sleep apnea and rapid eye movement-related obstructive sleep apnea in similar hearing threshold groups by Sun Choi, Seok Hyun Park, Su Yeon Kim, Su Kyoung Park, Sang Chul Park, Jiwon Chang

“…Objectives: Obstructive sleep apnea, a multisystem disease, affects cochlear and vestibular functions due to chronic intermittent hypoxia and recurrent oxygen desaturation. …”
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Biosynthesis of Zinc Oxide Nanoparticles Using Garlic Peel Extract and Their Antibacterial Potential by Ali Abdelmoteleb, Benjamín Valdez-Salas, Ernesto Beltran-Partida, Vianey Mendez-Trujillo, Daniel González-Mendoza, Olivia Tzintzun-Camacho, Ahmed F. Roumia

“…Based on the FTIR findings, the bioactive functional groups responsible for stabilizing and capping the ZnO-NPs were confirmed. …”
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Tenosynovial giant cell tumours of the foot and ankle: a retrospective single centre experience with surgical treatment of 34 cases by Christian Scheele, Norbert Harrasser, Simone Beischl, Dietmar Dammerer, Ulrich Lenze, Carolin Knebel, Rüdiger von Eisenhart-Rothe, Florian Lenze

“…It’s important for orthopaedic surgeons to weigh surgical margins against functional results, as stable outcomes appear to be attainable even in cases of residual or recurrent tumours.…”
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