Development of a High-Cell-Density Production Process for a Biotherapeutic Yeast, <i>Saccharomyces cerevisiae</i> var. <i>boulardii</i>, for Use as a Human Probiotic by Ghaneshree Moonsamy, Sarisha Singh, Yrielle Roets-Dlamini, Koketso Kenneth Baikgaki, Santosh Omrajah Ramchuran

“…However, there are limited data on its large-scale cultivation in stirred tank bioreactors and subsequent downstream processing into a functional probiotic product. Different recipe formulations were evaluated and the recipe with the highest biomass yield and lowest process time was selected. …”
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The UFMylation pathway is impaired in Alzheimer’s disease by Tingxiang Yan, Michael G. Heckman, Emily C. Craver, Chia-Chen Liu, Bailey D. Rawlinson, Xue Wang, Melissa E. Murray, Dennis W. Dickson, Nilufer Ertekin-Taner, Zhenkun Lou, Guojun Bu, Wolfdieter Springer, Fabienne C. Fiesel

“…Results Compared to controls, human AD brain had increased protein levels of UFM1. Our data further indicates that this increase mainly reflects conjugated UFM1 indicating hyperUFMylation in AD. …”
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Possibilities of Combination of Beta-blockers and Ivabradine in Patients with Stable Angina Pectoris by V. V. Kashtalap, O. L. Barbarash, D. Yu. Sedykh, K. E. Krivoshapova, D. P. Tsygankova, O. V. Tsygankova

“…Therapy with ivabradine (Bravadin) was well tolerated by patients: there were no adverse events in the observed sample of patients, patients had a high adherence to treatment (100% of the contents of handed out blisters were used). …”
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The Effect of Honey Powder Addition on Chosen Quality Properties of Model Chicken Products by Radosław Bogusz, Anna Onopiuk, Marta Chmiel, Anna Piotrowska, Eliza Kostyra, Edyta Lipińska, Joanna Bryś, Katarzyna Samborska, Dorota Pietrzak

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Ecological Momentary Assessment to Measure Social Connectedness in Older Adults: Integrative Review by Seongmi Choi, Hun Kang, Jiyoung Shin, Sang Hui Chu, JiYeon Choi

“…Social connectedness assessed via EMA mostly focused on the structural dimension, capturing whether an individual had social contact at a given moment (38/43, 88%). …”
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Åfficacy of nutraceutical drug in the intermediate and wet forms of age-related macular degeneration by E. N. Eskina, A. V. Belogurova, A. A. Gvetadze, A. S. Smorchkova

“…In the first part of the study, we monitored 46 patients with intermediate AMD threatening the progression of the disease (those with multiple confluent drusen, drusenoid, pigment epithelium detachment) for a year: some of them received the drug while others had no nutraceutical support. We assessed standard visual functions, as well as reading parameters (on the Salzburg Reading Desk device), spatial frequency contrast sensitivity (SFC) according to the Zebra program, and macular pigment optical density (on the MPOD device). …”
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Prevalence and Diagnostic Strategies for Sarcopenia in Menopausal and Non-Menopausal Women: A Cross-Sectional Comparative Study by Li M, Yan X, Wu R, Liao Y, Zhang J, Ye Y, Xu C

“…Sarcopenic individuals had lower BMI and poorer functional performance. …”
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Factors influencing survival outcomes in patients with stroke at three tertiary hospitals in Zimbabwe: A 12-month longitudinal study. by Farayi Kaseke, Lovemore Gwanzura, Cuthbert Musarurwa, Elizabeth Gori, Tawanda Nyengerai, Timothy Kaseke, Aimee Stewart

“…<h4>Conclusion</h4>The study findings demonstrate that hospital bill payment methods, housing status and staying with relatives, educational attainment, functional outcome, and age significantly affect survival outcomes among stroke patients. …”
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Evaluation of small vessel disease burden on MRI and stroke outcomes by Janet Nguyen, Nicholas Vo, Nicholas Vo, Peter D. Chang, Peter D. Chang, Chanon Chantaduly, Wengui Yu, Jennifer E. Soun, Jennifer E. Soun

“…The combined SVD + clinical factors model outperformed other models in predicting functional independence with area under the curve (AUC) 0.58 (95% CI 0.41–0.75) and stroke etiologies of large artery atherosclerosis AUC 0.78 (0.62–0.91), small vessel occlusion 0.65 (0.41–0.88), and other determined etiology 0.74 (0.37–0.96). …”
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Integration of transcriptome and immunophenotyping data highlights differences in the pathogenetic kinetics of B cells across immune-mediated disease by Kazuhiko Yamamoto, Mineto Ota, Keishi Fujio, Yasuo Nagafuchi, Tomohisa Okamura, Saeko Yamada, Hirofumi Shoda, Takahiro Itamiya, Toshihiko Komai, Shinji Izuka, Kosuke Matsuki

“…Higher disease activity in rheumatoid arthritis and decreased respiratory functions in systemic sclerosis were observed in cluster 1, whereas the disease activity of systemic lupus erythematosus was higher in cluster 2. …”
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Ground‐Dwelling Spider Community Responses to Forest Management in a Mediterranean Oak Forest by Claire Ménival, Mathieu Santonja, Christophe Mazzia, Valentin Spataro, Lenka Brousset, Daniel Pavon, Sylvie Dupouyet, Yoann Le Bagousse‐Pinguet, Raphaël Gros

“…We found clear‐cutting had a stronger effect than thinning on the microclimatic conditions, i.e., higher temperatures, drier soils and reduced forest buffering capacity. …”
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Assessment of lipid metabolism in thyroid dysfunction by V. G. Kadzharyan, A. I. Melnik, P. P. Bidzilya, S. A. Solovyuk

“…To define features of lipid metabolism, depending on the functional state of the thyroid gland. 3. Material and methods. …”
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Comparison of the clinical efficacy of patellar lateral retraction and patellar eversion in total knee arthroplasty: a systematic review and meta-analysis by Mingjie Dong, Xiaoyu Sun, Hao Fan, Weiping Ren, Yushan Wang, Yingjie Gao, Pengfei Shao, Yu Gao, Qiang Jiao, Yi Feng

“…Conclusions The PLR procedure is superior to PE in terms of blood loss, incision length, straight leg raise, knee ROM, VAS score (1 and 3 months), KSS functional score, and operative complications, although PE could decrease the operation time. …”
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Innovative approaches to improving the barrier properties of natural sausage casings by I. Simonova, U. Drachuk, B. Halukh, I. Basarab, H. Koval, Y. Nutskovskyi

“…Furthermore, all the plant-based extracts had a beneficial effect on water permeability, reducing it across the board. …”
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Distance visual acuity in air force pilots and student pilots when exposed to +Gz acceleration in human centrifuge by Ranđelović Danijela, Srećković Sunčica, Šarenac-Vulović Tatjana, Petrović Nenad

“…Substantial changes in visual functions may occur during high acceleration onset rates. …”
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Low storage temperature maintains the quality, antioxidant activity, and nutraceutical properties of edible flowers and their anti-inflammatory effects on RAW 264.7 cells by Mantana Buanong, Sudarat Khunmuang, Juthamard Promboon, Pathompong Penchaiya, Natnicha Promyos, Apanchanid Thepouyporn

“…Edible flowers are increasingly used as functional foods that enhance human health by providing antioxidant and antiaging benefits, scavenging free radicals, and aiding in the prevention and care of cardiovascular diseases and cancer. …”
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Iron metabolism and preeclampsia: new insights from bioinformatics analysis by Xijiao Guo, Sha Li, Guoping Xiong

“…ROC curve analysis demonstrated that all hub genes had good diagnostic value. The ssgsea scores indicated that hub genes were significantly associated with ferroptosis. …”
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The Significance of MAPK Signaling Pathway in the Diagnosis and Subtype Classification of Intervertebral Disc Degeneration by Yong Liu, Xueyan Chen, Jingwen Chen, Chao Song, Zhangchao Wei, Zongchao Liu, Fei Liu

“…To explore the biological functions of these differential genes in humans, we performed GO and KEGG analyses. …”
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Pulmonary hypertension associated with COPD: a phenotype analysis by Mathilde Steger, Matthieu Canuet, Guillaume Martin, Aissam Labani, Jean Charles Schwartz, Irina Enache, Armelle Schuller, Léo Meyer, Ari Chaouat, Romain Kessler, David Montani, Marianne Riou

“…The groups differed in terms of clinical, functional, haemodynamic and imaging characteristics. …”
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Comprehensive bioinformatics analysis of EXOSC family genes in head and neck squamous cell carcinoma by Xuezhong Zhang, Mengmeng Zhao, Tingting Chu, Jiasha Wei, Qingmei Jia

“…Gene co-expression and enrichment analyses were used to elucidate potential molecular functions, and a protein–protein interaction (PPI) network was constructed via GeneMANIA. …”
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