Evaluation of astaxanthin stability under varying temperatures and ultraviolet irradiation durations based on Raman spectroscopy by Xiaodan Liu, Wenjing Li, Zhiheng Yue, Jiangjin Qian, Wenjing Zhu, Huang Dai, Jiahua Wang, Fuwei Pi

“…The peak intensity ratio of I1518/I880 had been selected as the optimal Raman spectral variable for AST degradation based on Pearson's correlation analysis. …”
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P4HA2 promotes proliferation, invasion, and metastasis through regulation of the PI3K/AKT signaling pathway in oral squamous cell carcinoma by Zengpeng Chi, Qimin Wang, Xin Wang, Dagang Li, Lei Tong, Yu Shi, Fang Yang, Qingyuan Guo, Jiawei Zheng, Zhenggang Chen

“…This study focused on investigating the expression patterns, carcinogenic functions, and underlying mechanisms of P4HA2 in OSCC cells. …”
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In Vivo and In Vitro Evaluation of the Feasibility and Safety Profiles of Intraarticular Transplantation of Mitochondria for Future Use as a Therapy for Osteoarthritis by Carlos Vaamonde-Garcia, Tamara Hermida-Gómez, Sara Paniagua-Barro, Elena F. Burguera, Francisco J. Blanco, Mercedes Fernández-Moreno

“…The isolated mitochondria were injected into joint tissue using both in vitro and in vivo models. Functional mitochondria were detected in the extracellular matrix of the cartilage, menisci and synovium. …”
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Revealing the significance of tissue-resident memory T cells in lung adenocarcinoma through bioinformatic analysis and experimental validation by Zhuoqi Li, Mei Tian, Yuanhui Yang, Yuanyuan Wang, Lu Zhang, Fujing Huang, Xiao Wen, Xiaoshu Yin, Xiaoyan Lin, Xiaoyan Lin, Yuan Tian

“…The AUCs for predicting the 1-, 3-, and 5-year survival rates were 0.688, 0.698, and 0.648, respectively, in the training cohort, and were 0.867, 0.662, and 0.672, respectively, in the validation cohort. The signature also had predictive value for the sensitivity of patients to chemical drugs. …”
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Bivalve monitoring over French coasts: multi-decadal records of carbon and nitrogen elemental and isotopic ratios as ecological indicators of global change by C. Liénart, A. Fournioux, A. Garbaras, H. Blanchet, N. Briant, S. F. Dubois, A. Gangnery, A. Grouhel Pellouin, P. Le Monier, A. Lheureux, X. de Montaudouin, N. Savoye

“…<p>Recent changes in climate and environment, influenced by both global and local factors, have had profound impacts on coastal ecosystem functioning and trajectories. …”
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Could we stimulate melatonin secretion through Tahajjud? by akram heidari, Ali Fattahi Bafghi, Sayyed Ziaadin Tabeaie, Reza Bani- Asadi, Mohammad afkhami Ardakani, Kazem Barzegar, mahmood vakili, morteza heidari

“…This is the time of maximum melatonin secretion, that is a hormone mainly functioning in the circadian rhythm. Melatonin secretion declines with age and leads to different clinical consequences. …”
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Characteristics of biological parameters and implantable collamer lens (ICL) size selection in moderate, high, and super-high myopia eyes by Fei Li, Yueni Ma, Wenjie Qi, Emmanuel Eric Pazo, Ruibo Yang, Shaozhen Zhao

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A minimal gene set characterizes TIL specific for diverse tumor antigens across different cancer types by Zhen Zeng, Tianbei Zhang, Jiajia Zhang, Shuai Li, Sydney Connor, Boyang Zhang, Yimin Zhao, Jordan Wilson, Dipika Singh, Rima Kulikauskas, Candice D. Church, Thomas H. Pulliam, Saumya Jani, Paul Nghiem, Suzanne L. Topalian, Patrick M. Forde, Drew M. Pardoll, Hongkai Ji, Kellie N. Smith

“…Collectively, we show that MANAscore is a robust tool that can greatly enrich candidate tumor-specific T cells and be used to understand the functional programming of tumor-reactive TIL.…”
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<i>Zea mays</i>-Derived Protein Hydrolysate and Diverse Application Modes Differentially Compose Crop Production and Fruit Quality of Strawberry Cultivated Under Tunnel by Fabiana Mancuso, Lorena Vultaggio, Leo Sabatino, Pietro Bellitto, Georgia Ntatsi, Enrica Allevato, Gaetano Giuseppe La Placa, Salvatore La Bella, Beppe Benedetto Consentino

“…Captivatingly, plants biostimulated via fertigation showed the highest fruit potassium (K) concentration, while those exposed to the foliar spray had the highest fruit phenolic concentration. Generally, our findings recommended that the application of <i>Zea mays</i>-derived PH via foliar spray could be considered a suitable tool to increase functional traits of strawberry grown under tunnel.…”
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Efficacy of Subantimicrobial Dose Doxycycline for Moderate-to-Severe and Active Graves’ Orbitopathy by Miaoli Lin, Yuxiang Mao, Siming Ai, Guangming Liu, Jian Zhang, Jianhua Yan, Huasheng Yang, Aimin Li, Yusha Zou, Dan Liang

“…Secondary outcome was the change of quality of life score (QoL, including visual functioning subscale and appearance subscale). Adverse events were also recorded. …”
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Targeted Screening of <i>Lactiplantibacillus plantarum</i> Strains Isolated from Tomatoes and Its Application in Tomato Fermented Juice by Nuersiman Tuerhong, Liang Wang, Jie Cui, Dilireba Shataer, Huizhen Yan, Xiaoxiao Dong, Ziqi Gao, Minwei Zhang, Yanan Qin, Jing Lu

“…This study explores the functional attributes of <i>Lactiplantibacillus plantarum</i> (<i>L. plantarum</i>) strains isolated from fermented tomato juice, focusing on their physiological, biochemical, and probiotic characteristics. …”
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Dissecting the genetic basis of fruiting efficiency for genetic enhancement of harvest index, grain number, and yield in wheat by Dipendra Shahi, Jia Guo, Md Ali Babar, Sumit Pradhan, Muhsin AVCI, Jordan McBreen, Zhao Liu, Guihua Bai, Paul St. Amand, Amy Bernardo, Matthew Reynolds, Gemma Molero, Sivakumar Sukumaran, John Foulkes, Jahangir Khan

“…Results FE showed significant positive associations with GN, grain yield (GY), and harvest index (HI). Likewise, TGW mostly had a positive correlation with GY and HI, but a negative correlation with GN. …”
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Comparison of Deep Learning Models for LAI Simulation and Interpretable Hydrothermal Coupling in the Loess Plateau by Junpo Yu, Yajun Si, Wen Zhao, Zeyu Zhou, Jiming Jin, Wenjun Yan, Xiangyu Shao, Zhixiang Xu, Junwei Gan

“…As the world’s largest loess deposit region, the Loess Plateau’s vegetation dynamics are crucial for its regional water–heat balance and ecosystem functioning. Leaf Area Index (LAI) serves as a key indicator bridging canopy architecture and plant physiological activities. …”
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Effects of Grazing in a Low Deciduous Forest on Rumen Microbiota and Volatile Fatty Acid Production in Lambs by Raúl Ávila-Cervantes, Pedro González-Pech, Carlos Sandoval-Castro, Felipe Torres-Acosta, José Ramos-Zapata, Mónica Galicia-Jiménez, Ramón Pacheco-Arjona

“…Moreover, significant functional profiles are associated with key metabolic pathways in bacteria and are interconnected by the need to generate energy and biosynthetic precursors and to manage available nitrogen and carbon. …”
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Long-term inhibition of Hepatitis B virus gene expression by a primary microrna expressing ancestral adeno-associated viral vector by Njabulo Ziphezinhle Mnyandu, Shonisani Wendy Limani, Abdullah Ely, Reubina Wadee, Patrick Arbuthnot, Mohube Betty Maepa

“…Targeting HBx, which is required for transcriptional activity of covalently closed circular DNA of HBV, makes this Anc80L65-derived vector a promising candidate for functional cure from chronic HBV infection.…”
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Perindopril Ameliorates Sodium Valproate-Induced Rat Model of Autism: Involvement of Sirtuin-1, JAK2/STAT3 Axis, PI3K/Akt/GSK-3β Pathway, and PPAR-Gamma Signaling by Anwar M. Alnakhli, Asmaa Saleh, Ahmed M. Kabel, Remon S. Estfanous, Hany M. Borg, Khulud M. Alsufyani, Nesreen M. Sabry, Fatma Alzahraa M. Gomaa, Maaly A. Abd Elmaaboud

“…<i>Background and Objectives:</i> Autism is a developmental disability characterized by impairment of motor functions and social communication together with the development of repetitive or stereotyped behaviors. …”
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Cognitive Correlates of Borderline Personality Disorder Features in Youth with Bipolar Spectrum Disorders and Bipolar Offspring by Alessio Simonetti, Sherin Kurian, Evelina Bernardi, Antonio Restaino, Francesca Bardi, Claudia Calderoni, Gabriele Sani, Jair C. Soares, Kirti Saxena

“…<b>Results:</b> Youth with BD and BD-OFF showed higher scores on the BPFS-C. Youth with BD had increased deficits in the CGT and SOC compared to HCs. …”
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Therapeutic Effects of Mesenchymal Stem Cell Conditioned Medium in Rat Varicocele Model by Ege Can Serefoglu, Bircan Kolbasi, Muhammet Volkan Bulbul, Seda Karabulut, Cagri Cakici, Reyhan Zeynep Gundogdu Ozdemir, Ilknur Keskin

“…Additionally, Western Blot analyzes were performed to detect Claudin-11 levels, the functional protein of the blood-testis barrier, in testicular tissues. …”

Integrative analysis of anoikis-related prognostic signature to evaluate the immune landscape and predict therapeutic response in stomach adenocarcinoma by Ziyi Zhou, Lanlan Yang, Yuan Fang, Rongzhong Xu, Xi Wang, Yuli Wang, Zhihong Fang

“…In this study, we used the TCGA-STAD database to identify the expression patterns and prognostic relevance of anoikis-related genes (ARGs) in STAD. Functional enrichment analysis was used to explore the potential pathway. …”
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CARDIAC RESYNCHRONIZATION THERAPY WITH OR WITHOUT AN IMPLANTABLE CARDIOVERTER DEFIBRILLATOR IN DIFFERENT GROUPS OF HEART FAILURE PATIENTS by Perisic Zoran, Kostic Tomislav, Ilic Stevan, Koracevic Goran, Djindjic Boris, Milic Dragan, Vladimir Mitov, Salinger Martinovic Sonja, Stanojevic Dragana, Golubovic Mladjan

“…Patients with both CRT-P and CRT-D showed improvement in heart failure symptoms and CRT had significant influence on disease prognosis during 1 year of follow up. …”
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