Cost-effectiveness of percutaneous mitral repair for patients with severe secondary mitral regurgitation: an updated evaluation using a modelling approach based on COAPT final data... by Xavier Armoiry, Peter Auguste, Martin Connock, Jean-Francois Obadia

“…At a threshold of €50 000 per QALY, PR had a 0.85 probability of being cost-effective.Conclusion Updated trial data have enabled investigators to provide a more reliable estimation of the ICER, which suggests that PR has good value for money compared with GDMT alone.…”
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Utilization of Teacher Supervision Tool in Influencing Teacher Effectiveness in Secondary Schools in Rukungiri District – Uganda by Evans, Tayebwa

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Coverage of the lower third of the limb and foot injuries using reverse sural fasciocutaneous flap described by Carriquiry by Camila Garcia Sommer, Aluísio Marino Roma, Lauro Arnoldo Ferreira Koehler, Cristiane Camargo Ferreira, Verena Benedick Coimbra, Antonio Roberto Bozola

“…It is relatively easy to make, with good vascular supply, and there is no functional loss of the donor area.…”
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Postoperative delirium in patients undergoing TAVI versus SAVR – A systematic review and meta-analysis by Dimitrios Stavridis, Angelique Runkel, Anna Starvridou, Johannes Fischer, Luca Fazzini, Hristo Kirov, Max Wacker, Jens Wippermann, Torsten Doenst, Tulio Caldonazo

“…Background: Transcatheter Aortic Valve Implantation (TAVI) and Surgical Aortic Valve Replacement (SAVR) have different levels of invasiveness which can result in different levels of functional status after the procedure. Methods: We performed a systematic review and meta-analysis to detect studies showing direct comparison between TAVI and SAVR regarding postoperative functional status. …”
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Gamma entrainment induced by deep brain stimulation as a biomarker for motor improvement with neuromodulation by Varvara Mathiopoulou, Jeroen Habets, Lucia K. Feldmann, Johannes L. Busch, Jan Roediger, Jennifer K. Behnke, Gerd-Helge Schneider, Katharina Faust, Andrea A. Kühn

“…Recently it was shown that DBS entrains gamma activity at 1:2 of the stimulation frequency; however, the functional role of this signal is not yet fully understood. …”
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Perinatal Mother-to-Child Chikungunya Virus Infection: Screening of Cognitive and Learning Difficulties in a Follow-Up Study of the Chimere Cohort on Reunion Island by Raphaëlle Sarton, Magali Carbonnier, Stéphanie Robin, Duksha Ramful, Sylvain Sampériz, Pascale Gauthier, Marc Bintner, Brahim Boumahni, Patrick Gérardin

“…The difficulties observed affected verbal functions, non-verbal functions, and learning abilities, such as phonology, lexical evocation and comprehension, graphism, selective visual attention, planning, visual–spatial reasoning, dictation and mathematics, as well as core executive functions, such as inhibitory control, shifting, and working memory. …”
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Evaluation of Minds in Motion, a fitness program for people living with dementia and their caregivers by Pria Nippak, Jocelyn Badali, Julien Meyer, Housne Begum, Nalini Sen, Mya Rana-Nippak

“…Conclusion: This study, as an extension of the pilot, concluded that Minds in Motion program had a positive impact on PWD and CP's physical functioning following the program fitness training combined with mindfulness recreational activities, which aligned with their reported program satisfaction. …”
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Genetics and Traumatic Brain Injury: Findings from an Exome-Based Study of a 50-Patient Case Series by Alesya S. Gracheva, Darya A. Kashatnikova, Ivan V. Redkin, Vladislav E. Zakharchenko, Artem N. Kuzovlev, Lyubov E. Salnikova

“…We focused on rare, potentially functional missense and high-impact variants in genes intolerant to these variants. …”
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Excellent mechanical properties of a novel double-diagonal reinforced mechanical metamaterial with tunable Poisson’s ratios inspired by deep-sea glass sponges by Hongbo Zhang, Yuan Li, Zhiqian Lin, Zhen Zhang, Dayong Hu, Zhenyu Yang

“…In the realm of mechanical metamaterials, those exhibiting high strength and tunable properties were pivotal for advancing smart functionality applications. Inspired by the robust structure of deep-sea glass sponges, the double-diagonal reinforced metamaterial had been recognized for its exceptional mechanical properties. …”
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Oral administration of anti-lipopolysaccharide factor isoform 3 via the bait microalga for controlling bacterial infection of Atlantic Bay scallop (Argopecten irradians) by Yulin Cui, Ping Liu, Yaping Shao, Fengjie Sun, Qiaolei Wang, Hao Zhang, Yan Cheng, Zhengquan Gao

“…Combined with changes in immune factors and endotoxin, it indicated that exogenous ALFPm3–2 played antimicrobial and anti-inflammatory functions in the guts of bay scallops. Overall, this study provided strong evidence to support the oral administration of antimicrobial peptides via microalgae in aquaculture.…”
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A gastronomic exploration of protein digestibility, antioxidant activity, and bioavailability of selenium-enriched germinated brown rice under various cooking methods by Muhammad Tayyab Rashid, Kunlun Liu, Mengru Ning, Mushtaq Ahmed Jatoi, Nazish Muzaffar, Hazrat Usman

“…These findings emphasise the stability and functionality of selenium-enriched brown rice, highlighting its potential as a functional food to address dietary selenium deficiencies and promote public health.…”
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Understanding the effectiveness and underlying mechanisms of lifestyle modification interventions in adults with learning disabilities: a mixed-methods systematic review by Dikshyanta Rana, Sophie Westrop, Nishant Jaiswal, Evi Germeni, Arlene McGarty, Louisa Ells, Phillippa Lally, Michael McEwan, Craig Melville, Leanne Harris, Olivia Wu

“…However, the interventions had a varying level of statistical significance. …”
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SS-OCT-based ocular biometric characteristics of patients with nuclear cataract by Zhao Xu, Ke Yin, Liming Wang, Lijie Dong, Jing Sun, Aihua Liu

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Purification and Identification of Flavonoids from <i>Prunus mume</i> and Its Anti-Photoaging Activities on UVB-Induced Human Keratinocytes by Yuxuan Liu, Mengdie He, Xinxin Wei, Qifeng Han, Xiang Yang, Gangyi Huang, Chen Zhang, Mengqi Wu, Wenqing Zhang

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Sintomas neuropsiquiátricos nas demências: relato preliminar de uma avaliação prospectiva em um ambulatório do Brasil Neuropsychiatric symptoms in dementias: preliminary report of... by Úrsula Maria Vega, Valeska Marinho, Eliasz Engelhardt, Jerson Laks

“…Psychotic symptoms had negative effects on daily activities of outpatients and were associated with functional decline.…”
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Study on Quality of Life of Patients with Obstructive Sleep Apnea—Pilot Study by Olja Tanellari, Brunilda Koci, Edlira Baruti Papa, Carina Balcos, Adina Oana Armencia, Tinela Panaite, Irina Zetu

“…<i>Background and Objectives</i>: Sleep apnea (OSA) significantly impacts patients’ health, affecting cognitive, emotional, and social functioning, thus reducing overall quality of life (QoL). …”
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Plant AT-rich protein and zinc-binding protein (PLATZ) family in Dendrobium huoshanense: identification, evolution and expression analysis by Fangli Gu, Yanshuang Ren, Muhammad Aamir Manzoor, Tingting Wang, Renshu Huang, Naifu Chen, Cheng Song, Yingyu Zhang

“…The genome-wide identification of D. huoshanense elucidates the functions and regulatory processes of the gene family. …”
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Effect of juvenile social isolation on excitability of prefrontal pyramidal cells with different subcortical axonal projections by Yosuke Nishihata, Hiroki Yoshino, Hiroki Yoshino, Yoichi Ogawa, Taketoshi Sugimura, Kazuya Okamura, Sohei Kimoto, Kazuhiko Yamamuro, Kazuhiko Yamamuro, Manabu Makinodan, Yasuhiko Saito, Toshifumi Kishimoto

“…We elucidated differences in functional properties among the three subclasses of L5 pyramidal cells and examined how JSI affects the intrinsic membrane properties and excitatory inputs for each class of L5 pyramidal cells.ResultsPyramidal cells projecting to the pontine nuclei had more excitatory synaptic inputs and more distinguishing intrinsic properties than pyramidal cells projecting to the mediodorsal thalamus and striatum. …”
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Clinical significance of altered expression of mitochondrial genome-derived LncRNA LIPCAR in colorectal cancer by Seyed Taha Nourbakhsh, Fatemeh Mohamadhashem, Mohammad Mehdi Naghizadeh, Amirnader Emami Razavi, Abdolreza Daraei, Faezeh Mohamadhashem

“…However, this hypothesis necessitates further validation through comprehensive functional studies conducted both in vitro and in vivo.…”
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Modifiable risk factors and symptom progression in dementia over up to 8 years—Results of the DelpHi‐MV trial by Iris Blotenberg, Felix Wittström, Bernhard Michalowsky, Moritz Platen, Diana Wucherer, Stefan Teipel, Wolfgang Hoffmann, Jochen René Thyrian

“…Education initially had a protective effect, whereas depressive symptoms were linked to worse symptom progression. …”
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