Construction of a macrophage-related prognostic signature and assessment of immune checkpoint inhibitor efficacy of HCC by Shouge Zang, Hongwei Chen, Yuqian Han, Di Cui, Jiangtao Yu

“…An eight-gene macrophage-related signature showed strong prognostic and predictive value. High-risk patients had poorer survival and reduced ICI responsiveness. …”
Get full text

Synthetic Site-Selectively Mono-6-O-Sulfated Heparan Sulfate Dodecasaccharide Shows Anti-Angiogenic Properties In Vitro and Sensitizes Tumors to Cisplatin In Vivo. by Egle Avizienyte, Claire L Cole, Graham Rushton, Gavin J Miller, Antonella Bugatti, Marco Presta, John M Gardiner, Gordon C Jayson

“…Heparan sulphate (HS), a ubiquitously expressed glycosaminoglycan (GAG), regulates multiple cellular functions by mediating interactions between numerous growth factors and their cell surface cognate receptors. …”
Get full text

Impact of LDL-C levels on severity and outcome of intracranial haemorrhage: a single-centre retrospective study by Kang-Po Lee, Li-Chi Hsu

“…Our results confirmed that LDL-C is independently correlated with more severe ICH, poorer discharge functional status and higher short-term and long-term mortality in ICH patients. …”
Get full text

Static Traction and Early Mobilization Protocol for Intra-articular Fractures of Proximal Interphalangeal Joint: Technique and Outcome by Nilesh D Darawade, Praveen Bhardwaj, Raja Sabapathy Shanmuganathan

“…Despite suboptimal radiographs, patients had a functional, painless range of motion. All patients went back to previous work. …”
Get full text

The effect of the <i>Ant25</i>, <i>Ant26</i> and <i>Ant27</i> loci controlling proanthocyanidin synthesis in barley (<i>Hordeum vulgare</i> L.) grain on plant growth and developmen... by I. V. Totsky, R. Li, O. Yu. Shoeva

“…Mutants at the Ant25, Ant26 and Ant27 loci with unknown molecular functions can be used as donors of recessive alleles of the genes specifically controlling proanthocyanidin synthesis in barley grain. …”
Get full text

Dynamics of interstitial lung disease following immunosuppressive treatment differ between antisynthetase syndrome and systemic sclerosis by Ophir Freund, Tali Eviatar, Roni Meidan, Tamar Shalmon, Dana Stav, Tzlil Hershko, Tal Moshe Perluk, Ori Wand, Sonia Schneer, Yochai Adir, David Shitrit, Ori Elkayam, Amir Bar-Shai, Avraham Unterman

“…Changes in FVC% and DLCOc% were higher in the ASS group compared with SSc ( p  = 0.017 and p  < 0.01, respectively), which persisted after adjustment to steroid use and in a sub-analysis of patients with serial pre- and post-IST pulmonary functions. Both groups had improved total CT scores after IST, without changes in other radiologic scores. …”
Get full text

Smoking status and the efficacy of remote ischaemic conditioning: a secondary analysis of the RICAMIS trial by Yu Cui, Hui-Sheng Chen, Xian-Wen Zhang

“…The interaction analysis revealed no significant association between smoking status and RIC efficacy (P for interaction=0.50).Conclusions In this analysis, RIC significantly improved the excellent functional prognosis of non-smoking stroke patients, but had no significant benefit for current smokers, suggesting that smoking may attenuate RIC efficacy.Trial registeration number NCT03740971.…”
Get full text

Comparison of Motion Control Screening Test Scores in Active Women With a History of Knee and Ankle Injuries by Maryam Golmoradi Marani, Amir Letafatkar, Seyed Sadredin Shojaedin

“…Conclusion: The scores of functional movement screening give a detailed model of the injury prevention to coaches in order to predict the risk of lower extremity injuries in athletes. …”
Get full text

Surgical treatment of unstable pelvic ring fractures by Kezunović Miroslav, Bulatović Nikola

“…Two infections occurred around Steinman pins in the patients who had the definitive treatment performed with external fixator. …”
Get full text

Physical activity for children and adolescents with attention deficit hyperactivity disorder: a protocol of a systematic review and meta-analysis by Ole Jakob Storebø, Marie-Louise Jensen, Merete Bender Bjerrum, Marianne Vamosi

“…The main objective of the review is to examine the effect of physical activity on QoL, executive functions, symptoms and functional impairment in this population. …”
Get full text

S100A9 induced inflammatory responses are mediated by distinct damage associated molecular patterns (DAMP) receptors in vitro and in vivo. by Bo Chen, Allison L Miller, Marlon Rebelatto, Yambasu Brewah, Daniel C Rowe, Lori Clarke, Meggan Czapiga, Kim Rosenthal, Tomozumi Imamichi, Yan Chen, Chew-Shun Chang, Partha S Chowdhury, Brian Naiman, Yue Wang, De Yang, Alison A Humbles, Ronald Herbst, Gary P Sims

“…Release of endogenous damage associated molecular patterns (DAMPs), including members of the S100 family, are associated with infection, cellular stress, tissue damage and cancer. The extracellular functions of this family of calcium binding proteins, particularly S100A8, S100A9 and S100A12, are being delineated. …”
Get full text

Effect of <i>Enterococcus hirae</i> GS22 Fermentation-Assisted Extraction on the Physicochemical and Bioactivities of Sea Cucumber Intestinal Polysaccharides by Xiqian Tan, Xiaoqing Wang, Fangchao Cui, Ali Zeshan, Dangfeng Wang, Xuepeng Li, Jianrong Li

“…Fermentation does not change the functional group or the thermal ability of the polysaccharide. …”
Get full text

Confixal derivatives with initial bez- in Old Russian chronicles by Irina V. Erofeeva, Yulia K. Lukoyanova

“…The aim of the study is a comprehensive structural-semantic, functional, and conceptual analysis of confixal nominal forms with the initial bez- in the Old Russian language. …”
Get full text

Quince Powder Increases Antioxidant Activity and Probiotic Survival in Yoghurt by Şenay Burak Çınar, Gülfem Ünal, Gülşah Çalışkan Koç, Safiye Nur Dirim, Ayşe Sibel Akalın

“…In recent years, there has been a growing interest in incorporating fruit-based additives into yogurt formulations as a means to improve the functionality of the product. This study aims to produce a functional product by incorporating quince, which is rich in fibre, vitamins, minerals and antioxidant activity, into a yoghurt formulation. …”
Get full text

Biopsychosocial Correlates of Adjustment to Cancer during Chemotherapy: The Key Role of Health-Related Quality of Life by Marco Lauriola, Manuela Tomai

“…We found a negative association between advanced stage and physical functioning, a strong positive link between physical functioning and mental health, and significant relations between mental health and helpless-hopelessness, anxious preoccupation, and cognitive avoidance. …”
Get full text

Activity of Cefiderocol and Other New Antibiotics Against Extensively Drug-Resistant <i>Klebsiella pneumoniae</i> Strains by E. V. Karpova, D. V. Tapalski

“…These were NDM and OXA-48-producers isolated from hospitalized patients with COVID-19 infection from 3 regions of Belarus. Resistant strains had functionally significant nonsynonymous  substitutions in the genes of TonB-dependent receptors for catecholate siderophores FepA (F472V, P64S) and Fiu (T92S).Conclusion. …”
Get full text

Production of Brown Rice Fermented by Ganoderma lucidum by GU Dandan, DONG Xue, ZHANG Jinxiu, LÜ Jianhua, LI Zhuang, QI Yonghao, WANG Li’an

“…The instant rice porridge containing BRFG flour as the primary ingredient had good visual appearance and taste. This study demonstrates that BRFG possess improved nutritional quality and functional characteristics than does brown rice, providing substantial support for its industrial production and multi-scenario application and offering guidance for the development of new functional and nutritional foods.…”
Get full text

Performance evaluation of anti-avalanche measures at the «Krasnaya Polyana» ski resort by D. I. Korovina, A. S. Turchaninova, S. A. Sokratov

“…Snow-retaining structures often do not perform their functions, while dams and avalanche cutters can be successful only in combination with the properly functioning artificial triggering. …”
Get full text

Acute and chronic toxicity of an antifungal agent based on 1,2,4-triazole by S. Stratii, V. Hunchak, R. Vasiv, N. Koropetska, Kh. Leskiv

“…Observations of the test animals showed that they had a satisfactory appetite, were active and mobile, and their behavioral and reflex responses were preserved. …”
Get full text

Activities of Bishops’ council in solving problems of German diocese of Russian Orthodox Church Abroad in 1948–1950 by Aleksandr Kornilov

“…The article studies various issues in functioning of the Bishops’ Council of the German Diocese of the Russian Orthodox Church Abroad. …”
Get full text