Predictive outcome of late window ischemic stroke patients following endovascular therapy: a multi-center study by Sijie Zhou, Mohammad Mofatteh, Zhikai Chen, Zhikai Chen, Jinyan Tang, Jicai Ma, Ziqi Ouyang, Jian Wang, Senrong Luo, Yuankang He, Zhenzhang Li, Zhenzhang Li, Yuzheng Lai, Xuxing Liao

“…All patients were above 18 years of age and had symptoms onset of 6–24 h. mRS of 0–2 after three months was defined as favorable outcome.ResultsPatients with favorable outcome had lower median age (p = 0.003), lower pre-EVT National Institute of Health Stroke Scale (NIHSS) score (p = 0.000), lower diabetes mellitus (p = 0.041), stroke history (p = 0.041), parenchymal hematoma (PH) (p = 0.000) and fewer attempts to achieve successful recanalization (p = 0.001). …”
Get full text

Achieving Permanent Male Infertility by Magnetic Nanoparticle Hyperthermia: A Breakthrough in Animal Fertility Management by Juliana Lis Mendes Brito, Vanessa Nicolau Lima, José Luiz P. R. Jivago, Aline R. M. Marangon, Marcus Vinícius-Araújo, Andris Figueiroa Bakuzis, Juliana dos Anjos Ribeiro dos Santos, Paulo E. N. Souza, Ricardo Bentes Azevedo, Carolina Madeira Lucci

“…By the end of the experiment, all but two animals had no identifiable gonads. The only two animals still displaying gonadal-like structures were azoospermic, and histopathology revealed the remaining tissue was non-functional. …”
Get full text

Case report: A rare case of catastrophic Takayasu arteritis: acute ischemic stroke and anterior ischemic optic neuropathy by Oladotun V. Olalusi, Oladotun V. Olalusi, Joseph Yaria, Akintomiwa Makanjuola, Rufus Akinyemi, Rufus Akinyemi, Rufus Akinyemi, Mayowa Owolabi, Mayowa Owolabi, Mayowa Owolabi, Mayowa Owolabi, Mayowa Owolabi, Adesola Ogunniyi, Adesola Ogunniyi

“…There was a relative afferent pupillary defect (RAPD), with fundoscopy findings indicating optic disc pallor. She had expressive aphasia, right facial paresis, and right flaccid hemiparesis. …”
Get full text

Application of the Original Agroecological Survey and Indicator System tool (OASIS) to organic and conventional farms in Belgium, France, and Italy by Alexander Wezel, Alexander Wezel, Paola Migliorini, Paola Migliorini, Anna Brumer, Tommaso Gaifami, Tommaso Gaifami, Angelica Marchetti, Geoffrey Floymont, Garance Guizard, Elsa Michel, Marie-Alix Renaud, Karla Škorjanc, Nicolas Allard, Stefano Bocchi, Alain Peeters, Alain Peeters, Alain Peeters

“…Overall, organic farms had slightly higher scores compared to conventional farms for the five dimensions. …”
Get full text

Promoting the wellbeing of the whole person: a within-subjects mixed-methods study exploring the effects of the flourishing intervention among individuals with depressive symptoms by Camilla Casaletti Braghetta, Juliane Piasseschi de Bernardin Gonçalves, Willyane de Andrade Alvarenga, Richard G. Cowden, Richard G. Cowden, Clarice Gorenstein, Clarice Gorenstein, Giancarlo Lucchetti, Homero Vallada

“…The study included 98 participants (18–59 years) with moderate to moderately severe depressive symptoms on the Patient Health Questionnaire-9 (PHQ-9), who had completed elementary school or better, resided in São Paulo, and had internet access. …”
Get full text

Features of ankylosing spondylitis at different stages in men and women by I. A. Cherentsova, E. N. Otteva

“…The BASDAI and BASFI scores were similar in women at all stages of the disease (p>0.05). The men with nr-axSpA had the best functional status (p<0.01) with the same BASDAI activity (p>0.05) compared with those with AS. …”
Get full text

Early Correction of Malocclusion Using Planas Direct Tracks by Renata Reis dos Santos, Artênio José Isper Garbin, Cléa Adas Saliba Garbin

“…The patient, a 4-year-old girl, arrived to receive treatment due to a functional unilateral crossbite. When the mandible was moved to the centric position, it was observed that the teeth had occlusal trauma. …”
Get full text

Generational effects of biosynthesized titanium dioxide nanoparticles on bitter gourd growth and phytochemistry by Bimal Das, Bappa Paramanik, Dipak Kumar Murmu, Biman De, Partha Sarathi Patra, Prithwiraj Dey, Pradip Dey

“…Treatments with TiO2 NPs at the seedling stage had a substantial effect on catalase and peroxidase activities. …”
Get full text

Inhaled corticosteroid dose is associated with Pseudomonas aeruginosa infection in severe COPD by Antonio Oliver, Borja G Cosío, Hanaa Shafiek, Javier Verdú, Amanda Iglesias, Lluisa Ramon-Clar, Nuria Toledo-Pons, Carla Lopez-Causape, Carlos Juan, Pablo Fraile-Ribot

“…Cox regression analysis was performed to evaluate the risk factors associated to PsA infection and mortality.Results 358 patients (78% male, mean age 73±9 years) were enrolled and followed up for a median of 4 years (IQR=3–8). 173 patients (48.3%) had at least a positive culture for PsA. COPD-PsA had more frequent exacerbations, more severe airflow limitation and higher mortality (69.4% vs 46.5%, p<0.001). …”
Get full text

Clinical Predictors of Cognitive Impairment in a Cohort of Patients with Older Age Bipolar Disorder by Camilla Elefante, Giulio Emilio Brancati, Maria Francesca Beatino, Benedetta Francesca Nerli, Giulia D’Alessandro, Chiara Fustini, Daniela Marro, Gabriele Pistolesi, Filippo Baldacci, Roberto Ceravolo, Lorenzo Lattanzi

“…Additionally, the cognitively impaired group had a later onset of major mood episodes (<i>p</i> < 0.05), fewer lifetime depressive episodes (<i>p</i> = 0.006), a higher prevalence of vascular leukoencephalopathy (<i>p</i> = 0.022) and dyslipidemia (<i>p</i> = 0.043), a lower prevalence of agoraphobia (<i>p</i> = 0.040), worse global functioning (<i>p</i> < 0.001), and higher psychopathology severity (<i>p</i> < 0.001). …”
Get full text

Assessment of pH-Induced Conformational Changes in Whey Protein Isolate–Dextran Conjugate Using Spectral Technology by Qingyuan Dai, Huiqin Wang, Xiuling Zhu, Polyanna Silveira Hornung, Yuru Zhang, Wenxuan Hu, Anqi Lin, Anyi Yao, Trust Beta

“…The functional properties of proteins are closely related to their structure and conformation. …”
Get full text

Gender differences in the associations of recreational walking with indoor and outdoor falls among older adults-the Healthy Aging and Neighborhood Study (HANS) by Lingming Chen, Elizabeth Procter-Gray, Qun Le, Danielle LoPilato, Marianella Ferretto, Kevin Kane, Marian T. Hannan, Sarah Berry, Wenjun Li

“…Women engaging in recreational walking at least once weekly had a 62% lower indoor fall rate [IRR (95% CI): 0.38 (0.21, 0.71)] than those who did not. …”
Get full text

Preoperative Anteroposterior and Lateral Assessment of Sagittal Spinopelvic Parameters Show High Positional Correlation and Measurement Reliability Preceding Both Hip Preservation... by Benjamin D. Kuhns, M.D., M.S., Tyler R. McCarroll, M.D., Roger Quesada-Jimenez, M.D., Ady H. Kahana-Rojkind, M.D., Drashti Sikligar, M.Eng., Meredith F. Cohen, B.A., Benjamin G. Domb, M.D.

“…The APP, SPT, and pelvic inclination had lower reliability when compared with the sacral slope in the sitting position. …”
Get full text

Liprotide-encapsulated vitamin D3 modulates circulated PTH levels and improved bone microstructure by Claradhita Ayu Shauma, Faizah Fulyani, Adriyan Pramono, Endang Mahati, Sylvia Rahmi Putri, Reza Achmad Maulana, Gemala Anjani

“…Results: the VD-Ca rats supplemented with vitamin D3 (FVD3 and LVD3) had a significant decrease in serum PTH levels (p<0.001) and improved bone microstructure (p<0.05) compared to the (K-) group. …”
Get full text

The influence of microwave-assisted osmotic dehydration in coconut meat preservation technique by Mahfujul Alam, Mipahur Jannat, Nayon Datta, Mir Meahadi Hasan, Asraful Alam, Md. Ashrafuzzaman Zahid, Md. Shakir Moazzem, Mohammad Mainuddin Molla, Mrityunjoy Biswas

“…The coconut meat preserved in 80 % sugar solution with microwave treatment had significantly (p < 0.05) higher retention of the quality parameters compared to other treatments during storage. …”
Get full text

Mechanism of N-Acetyl-D-alloisoleucine in Controlling Strawberry Black Root Rot by Jialu Xu, Jianxiu Hao, Mingmin Zhao, Xiaoyu Zhang, Ruixiang Niu, Yiran Li, Zhen Wang, Shuo Zhang, Sumei Zhao, Siran Li, Hongyou Zhou

“…A total of 68 substances were identified, including 18 amino acids, 7 of which have been reported to have pro-growth and antibacterial functions. Among these seven amino acids, N-acetyl-D-alloisoleucine (NAD) had the strongest inhibitory effect on <i>F. asiaticum</i>. …”
Get full text

Health-related quality of life in patients with gastrointestinal stromal tumor: data from a real-world cohort compared with a normative population by D. van de Wal, D. den Hollander, I.M.E. Desar, H. Gelderblom, A.W. Oosten, A.K.L. Reyners, N. Steeghs, W.T.A. van der Graaf, O. Husson

“…Results: The global QoL of patients receiving imatinib in a curative setting (mean ± SD 81.2 ± 12.6) was comparable with the normative population (mean ± SD 77.1 ± 18.2), while patients who had completed their curative treatment [including those discharged from FU (mean ± SD 85.2 ± 14.0) and still in FU (mean ± SD 82.7 ± 15.0)] had a significant better global QoL with comparable functioning scores. …”
Get full text

CARDIOVASCULAR RISK IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS BEFORE DISEASE-MODIFYING ANTIRHEUMATIC THERAPY (PRELIMINARY DATA OF THE REMARCА STUDY) by Yu. N. Gorbunova, D. S. Novikova, T. V. Popkova, E. I. Markelova, Yu. O. Korsakova, O. A. Fomicheva, D. S. Kolmakova, E. L. Luchikhina, D. E. Karateev, A. V. Smirnov, E. L. Nasonov

“…Objective: to estimate the level of cardiovascular risk in patients with early rheumatoid arthritis (RA) before therapy with disease-modifying antirheumatic drugs (DMARDs).Subjects and methods: Seventy-three patients with early RA who had not previously taken DMARDs or glucocorticoids were examined. …”
Get full text

Germline variants of the genes involved in NF-kB activation are associated with the risk of COPD and lung cancer development by Baranasic Jurica, Niazi Yasmeen, Chattopadhyay Subhayan, Rumora Lada, Ćorak Lorna, Dugac Andrea Vukić, Jakopović Marko, Samaržija Miroslav, Försti Asta, Knežević Jelena

“…We extracted summary data of variants in 1511 immune-related genes from COPD and LC genome-wide association studies (GWAS) from the UK Biobank. The LC data had 203 cases, patients diagnosed with LC, and 360 938 controls, while COPD data had 1 897 cases and 359 297 controls. …”
Get full text

Prognostic importance of the Controlling Nutritional Status (CONUT) score in patients undergoing cardiac resynchronisation therapy by Yasuo Okumura, Yukitoshi Ikeya, Yuki Saito, Toshiko Nakai, Rikitake Kogawa, Naoto Otsuka, Yuji Wakamatsu, Sayaka Kurokawa, Kimie Ohkubo, Koichi Nagashima

“…The primary endpoint was all-cause mortality.Results The moderate or severe malnutrition group had a lower body mass index, more advanced New York Heart Association functional class, higher Clinical Frailty Scale score, lower levels of haemoglobin and higher levels of N-terminal probrain natriuretic peptide (all p&lt;0.05). …”
Get full text