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13321
Corrigendum to “Gene engineered exosome reverses T cell exhaustion in cancer immunotherapy” [Bioact. Mater. 34 (2024) 466–481]
Published 2025-10-01“…The results showed that PD1-Imi Exo had a vesicular round shape (approximately 139 nm), revealed a significant targeting and a strong binding effect with both cancer cell and dendritic cell, and demonstrated a remarkable therapeutic efficacy in the melanoma-bearing mice and in the breast cancer-bearing mice. …”
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13322
Multi-dimensional annotation of porcine variants using genomic and epigenomic features in pigs
Published 2025-07-01“…We further genome-wide annotated non-coding variants, and then focused on these resided in 5′ untranslated region (5′UTR). Although they had lower deleterious impact on protein sequence compared to coding variants, they enriched in promoters and exhibited functional consequences on gene expression and splicing and finally complex traits. …”
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13323
[Translated article] Concurrent upper limb and hip fracture in the elderly: Experience at our centre
Published 2025-05-01“…Our investigation aims to determine whether these patients experience poorer functional outcomes, prolonged hospitalisation, or higher mortality rates when compared to those with isolated hip fracture. …”
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13324
Selective neoadjuvant therapy of rectal cancer patients (SELREC): study protocol for a European randomised controlled, open, multicentre non-inferiority trial
Published 2025-06-01“…However, n(C)RT has demonstrated no significant impact on overall survival but is associated with adverse effects, including impaired sphincter and sexual function. We hypothesise that omitting n(C)RT in selected patients with a clear circumferential resection margin (CRM) >1 mm as determined through preoperative MRI is not inferior regarding local recurrence rate within 3 years after surgery. …”
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13325
The protective effects of Levilactobacillus brevis FZU0713 on lipid metabolism and intestinal microbiota in hyperlipidemic rats
Published 2023-09-01“…Therefore, L. brevis FZU0713 may be used as a potential probiotic strain to produce functional food to prevent hyperlipidemia.…”
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13326
Muscle Fat and Volume Differences in People With Hip‐Related Pain Compared With Controls: A Machine Learning Approach
Published 2024-12-01“…The CNN outperformed manual raters, who had slightly lower interrater accuracy (Sorensen–Dice index >0.800) and reliability (ICC2,1 > 0.800). …”
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13327
Asymmetrical Time-Lagged Response of Vegetation to Drought and Extreme Precipitation Across China
Published 2025-02-01“…NDVI had a strong positive correlation with drought and extreme precipitation in the arid regions, while in humid regions, it presented a strong correlation with drought during 2000–2015; however, a weak correlation with drought was found before the 21st century. …”
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13328
Light, humor and atoms: The physics of wine after Galilei
Published 2025-04-01“… Galileo’s interest in the nature and composition of wine, summarised in the saying “wine is a compound of humour and light” that is often ascribed to him, provided the basis for the research of the subsequent generation of scientists. These scientists had learned from their master how to approach the physics of wine in mechanistic and corpuscularian terms. …”
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13329
THE INFLUENCE OF ELECTROMAGNETIC RADIATION OF THE MILLIMETRE LENGTHS ON THE CLINICAL COURSE OF MYOCARDIAL INFARCTION
Published 2001-08-01“…The aim of the study was to evaluate the influence of electromagnetic radiation of the millciimeter lengths on the clinical course of myocardial infarction and the patients’ functional condition as assessed by veloergometry. We have studied 238 patients with myocardial infarction, including 164 men. 184 had primary and 54 – relapsing infar_ction. …”
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13330
Rheumatoid arthritis in real clinical practice. Results of the «Computer Terminals of Self-Assessment for Patients with Rheumatic Diseases» («TERMINAL-I») project
Published 2019-05-01“…Only 14.3% of patients had a good functional status that was comparable with the population-based control (HAQ≤0.5). …”
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13331
Abstract 055: Reperfusion Therapy for Acute Ischemic Stroke in Cardiomyopathy Patients with Heart Failure: A NIS‐based Analysis
Published 2023-11-01“…Introduction Cardiomyopathy (CM) is a diverse pathology defined by both structural and functional changes in the heart. Many studies have aimed to determine if heart failure (HF) is an independent risk factor in the development of AIS, but there is a paucity of literature describing the interventions and functional outcomes in this group of patients. …”
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13332
Floodplain Forest Soil Nematode Communities as Influenced by Non-Native <i>Acer negundo</i> L. Invasion
Published 2025-05-01“…Nevertheless, redundancy analysis identified a significant correlation between soil moisture content and abundance of several nematode genera, nematode trophic groups, and functional guilds. The results indicate that the presence of invasive ash-leaved maple trees in the studied floodplain forests had no adverse effect on the diversity and functional structure of soil nematode communities. …”
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13333
Comparative efficacy of cast immobilization versus removable braces in patients with ankle fractures: a systematic review and meta-analysis
Published 2025-03-01“…Conclusion Compared with cast immobilization, removable braces had better functional outcomes in the early and mid-term periods after ankle fractures and were less likely to result in deep vein thrombosis (DVT). …”
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13334
Menopausal hormone therapy affects quality of life in multimorbid late postmenopausal women
Published 2021-11-01“…Women with a low level of comorbidity who had previously received MHT have a significantly higher QoL. …”
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13335
Very early neurological deterioration during intravenous thrombolysis in patients with acute ischemic stroke
Published 2025-08-01“…Patients with VEND had a higher prevalence of intracranial atherosclerotic disease (41% vs. 17%, P = 0.005). …”
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13336
Clinico-epidemiological characteristics of patients with ankylosing spondylitis: experience from a specialized rheumatology centre in Bangladesh
Published 2025-03-01“…Conclusion Most of the patients in our study had experienced prolonged symptoms duration, elevated disease activity scores, restricted functional abilities, and increased levels of inflammatory markers. …”
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13337
Frequency and predictors of emergency department visits among the oldest old in Finland: the Vitality 90+ Study
Published 2025-06-01“…Not receiving home care, multimorbidity, poor subjective health and wellbeing, and limitations in functioning increased the risk of ED visits among home dwellers, while having dementia, limitations in functioning, impaired sensory functions, and less frequent social contacts decreased the risk among round-the-clock care residents. …”
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13338
Physical activity and nutritional profile assessment in elderly rheumatoid arthritis patients
Published 2025-04-01“…There was a statistically significant difference between RA patients and the control group regarding PA assessed by IPAQ-SF (p = 0.007) with (50%) of RA patients having low, whereas (50%) of the control group had high IPAQ-SF. There was a highly significant negative correlation of MNA-SF with laboratory markers of inflammatory activity, different activity indices, and functional capability assessed by a modified health assessment questionnaire (MHAQ). …”
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13339
La gestion de l’eau à Bibracte (Saône-et-Loire), avant et après la Conquête romaine
Published 2020-12-01“…Most of the wells were apparently destined for collective use because they were located in circulation areas, in the streets or squares. Other wells obviously had semi-private functions, installed in private areas but accessible from the street. …”
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13340
Low-dose fenfluramine as an effective treatment option for ‘atypical’ Dravet syndrome
Published 2024-01-01“…Here, we report a rare case of DS in a 14-year-old girl who was negative for genetic mutations, had experienced status epilepticus only once, and had abnormal findings on brain MRI. …”
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