Comparison of Serenoa repens, lycopene, and selenium versus dutasteride for the treatment of LUTS/BPH: an Italian multicenter case-control prospective study (COMP study) by Giuseppe Morgia, Arturo Lo Giudice, Sebastiano Cimino, Giulio Reale, Gaetano Larganà, Enza La Manna, Massimo Madonia, Alessandro Tedde, Francesco Santaniello, Giuseppe Vespasiani, Stefano Zaganelli, Salvatore Arnone, Nicola Cruciano, Maurizio Carrino, Francesco Persico, Carlo Terrone, Rafaela Malinaric, Andrea Minervini, Marco Carini, Giorgio Ivan Russo

“…IntroductionHistorically, medical therapy of BPH has had its foundations in alpha-blockers in monotherapy or in combination with 5 alpha reductase inhibitors (5-ARIs); in particular, two important trials (COMBAT and MTOPS) have demonstrated the pivotal role of combination therapy instead of monotherapy and have individuated which patients are most likely to benefit from alpha-blockers, 5-ARIs, or their combination. …”
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Chinese Fetal Growth: A Multicenter Cohort Study Based on Fetal Ultrasound Measurements by Xiaoli Gong, Tianchen Wu, Xiaoli Wang, Lizhen Zhang, Yiping You, Hongwei Wei, Xifang Zuo, Ying Zhou, Xinli Xing, Zhaoyan Meng, Qi Lyu, Zhaodong Liu, Jian Zhang, Liyan Hu, Junnan Li, Li Li, Chulin Chen, Chunyan Liu, Guoqiang Sun, Aiju Liu, Jingsi Chen, Yuan Lyu, Yuan Wei, Yangyu Zhao

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Isolation and Identification of <i>Burkholderia stagnalis</i> YJ-2 from the Rhizosphere Soil of <i>Woodsia ilvensis</i> to Explore Its Potential as a Biocontrol Agent Against Plant... by Xufei Zhu, Wanqing Ning, Wei Xiao, Zhaoren Wang, Shengli Li, Jinlong Zhang, Min Ren, Chengnan Xu, Bo Liu, Yanfeng Wang, Juanli Cheng, Jinshui Lin

“…We further knocked out core biosynthetic genes of two secondary metabolic gene clusters and found that only the YJ-2_GM006534-YJ-2_GM006569 gene cluster had a corresponding function in two potential antifungal gene clusters. …”
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Cohort profile: characterisation, determinants, mechanisms and consequences of the long-term effects of COVID-19 – providing the evidence base for health care services (CONVALESCEN... by Stefan Neubauer, Betty Raman, Michele Orini, Alun Hughes, Andrew Wong, Nishi Chaturvedi, Ellen J Thompson, Claire J Steves, Richard Dobson, Siana Jones, Iain Pierce, Carole Sudre, Amos Folarin, Stephen M Smith, Lucy J Goudswaard, Alicja Rapala, Dylan Williams, Yatharth Ranjan, James Wild, Nathan J Cheetham, Nic Timpson, Alexandra Jamieson, Lamia Al Saikhan, Lamis Alghamdi, Pauline Conde, Alba Fernández-Sanlés, Lee Hamill Howes

“…Of the 349 participants, 141 (53±15 years old; 21 (15%) men) were cases, 89 (55±16 years old; 11 (12%) men) were in control group 1, 75 (49±15 years old; 25 (33%) men) were in control group 2 and 44 (55±16 years old; 9 (21%) men) were in control group 3.Future plans The study aims to use a multiorgan score calculated as the cumulative total for each of nine domains (ie, lung, vascular, heart, kidney, brain, autonomic function, muscle strength, exercise capacity and physical performance). …”
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Atrial Fibrillation Risk Scores as Potential Predictors of Significant Coronary Artery Disease in Chronic Coronary Syndrome: A Novel Diagnostic Approach by Alexandru-Florinel Oancea, Paula Cristina Morariu, Maria Godun, Stefan Dorin Dobreanu, Miron Mihnea, Diana Gabriela Iosep, Ana Maria Buburuz, Ovidiu Mitu, Alexandru Burlacu, Diana-Elena Floria, Raluca Mitea, Andrei Vâță, Daniela Maria Tanase, Antoniu Octavian Petris, Irina-Iuliana Costache-Enache, Mariana Floria

“…Patients in the S-CCS group had significantly higher scores in CHA₂DS₂VA (4.09 ± 1.656 vs. 3.20 ± 1.338, <i>p</i> = 0.002), HAS-BLED (1.98 ± 0.760 vs. 1.36 ± 0.835, <i>p</i> < 0.001), CHA₂DS₂VA-HSF (6.00 ± 1.854 vs. 5.26 ± 1.712, <i>p</i> = 0.021), and C₂HEST (3.49 ± 1.501 vs. 2.55 ± 1.279, <i>p</i> < 0.001). …”
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The Study of Roadside Visual Perception in Internet of Vehicles Based on Improved YOLOv5 and CombineSORT by LI Xiaohui, YANG Jie, XIA Qin

“…To improve the convergence and reduce the complexity of the model, an advanced loss function of super-efficient IOU (SEIOU) and network pruning are applied. …”
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Efficacy of methylprednisolone sodium succinate combined with acoustic resonance therapy on inflammatory response indicators and cerebral microcirculation in patients with sudden s... by Jiangyuan Qin, Geng Huang, Xiaoyu Lin, Chang Su, Lingkan Chen, Lanfang Liao

“…By Day 60, combination therapy had the lowest severity (1.8 ± 0.7), confirming superior efficacy. …”
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Study the effect of Phosphate Barvar-2 Biofertilizer, Iron Nano-Chelate and Superabsorbent on qualitative and quantitative yield of chickpea (Cicer arietinum L.) under dry farming... by Omolbanin Hasanour, khosroo Azizi, Mohammad Feizian, Ahmad Ismaeili

“…According to the results, S2F2B2, S2F3B2, S1F3B2 and S1F2B2 had no significant difference in terms of grain yield and the highest and lowest grain yield by 1623 and 950 kg/ha obtained in S2F3B2 (superabsorbent, iron nano-chelate foliar application 2/1000 and phosphate Barvar-2) and S1F1B1 (control), respectively. …”
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Evaluation of rheumatoid arthritis-associated interstitial lung disease in patients treated with JAK inhibitors: a MAJIK-SFR cohort study by Adeline Ruyssen-Witrand, Jacques-Eric Gottenberg, Philippe Dieude, Rene-Marc Flipo, Jerome Avouac, Emanuelle Dernis, Anne Tournadre, Marie-Elise Truchetet, Raphaele Seror, André Ramon, Nicolas Roux, André Basch, Pascal Chazerain, Fabienne Coury-Lucas, Richard Damade, Pierre-Antoine Juge, Thao Pham, Clément Prati, Olivier Brocq, Jean Hugues Salmon, Christian hubert roux, Félicien Triboulet, Charles Leské, Émilie Shipley

“…Compared with the 778 RA patients without ILD from the MAJIK registry, RA-ILD patients were older, displayed more severe and active disease and had more prevalent comorbidities. Non-specific interstitial pneumonia and usual interstitial pneumonia accounted for 46% and 43% of the chest HRCT ILD patterns, respectively. …”
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Dual targeting of the mitochondrial Lon peptidase 1 and the chymotrypsin-like proteasome activity as a potential therapeutic strategy in malignant astrocytoma models by Christopher Douglas, Shashi Jain, Naomi Lomeli, Javier Lepe, Kaijun Di, Nitesh Kumar Nandwana, Adil Shareef Mohammed, Thao Vu, James Pham, Maria Cristina Kenney, Bhaskar Das, Daniela A. Bota

“…In vitro, BT317 had activity as a single agent but, more importantly, enhanced synergy with the standard of care commonly used chemotherapeutic temozolomide (TMZ). …”
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Interplay between the gut microbiome and typhoid fever: insights from endemic countries and a controlled human infection model by Philip M. Ashton, Leonardos Mageiros, James E. Meiring, Angeziwa Chunga-Chirambo, Farhana Khanam, Sabina Dongol, Happy Banda, Abhilasha Karkey, Lorena Preciado-Llanes, Helena Thomaides-Brears, Malick Gibani, Nazmul Hasan Rajib, Nazia Rahman, Prasanta Kumar Biswas, Md Amirul Islam Bhuiyan, Sally Kay, Kate Auger, Olivier Seret, Nicholas R. Thomson, Andrew J. Pollard, Stephen Baker, Buddha Basnyat, John D. Clemens, Christiane Dolecek, Sarah J. Dunstan, Gordon Dougan, Robert S. Heyderman, Virginia E. Pitzer, Firdausi Qadri, Melita A. Gordon, Kathryn E. Holt, Thomas C. Darton, STRATAA Study Group

“…Future research should explore the potential functional role of SCFAs and inflammation-associated bacteria in resistance to S. …”
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SEMANTIC TRANSFORMATIONS OF THE PARAGUAY LINGUISTIC SYSTEM COMPONENTS by Igor Yu. Protsenko, Irina I. Davtiants

“…They made them a part of the new system with which the Guarani world had come into contact. For example, to name the days of the week the Guarani have their own notions. …”
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Renal resistive index as an early predictor and discriminator of acute kidney injury in critically ill patients; A prospective observational cohort study. by Jelle L G Haitsma Mulier, Sander Rozemeijer, Jantine G Röttgering, Angelique M E Spoelstra-de Man, Paul W G Elbers, Pieter Roel Tuinman, Monique C de Waard, Heleen M Oudemans-van Straaten

“…Forty-nine patients (49%) developed AKI within the first week. AKI patients had a higher RRI on admission than those without: 0.71 (0.69-0.73) vs. 0.65 (0.63-0.68), p = 0.001. …”
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Responses of field-grown maize to different soil types, water regimes, and contrasting vapor pressure deficit by T. H. Nguyen, T. Gaiser, J. Vanderborght, A. Schnepf, F. Bauer, A. Klotzsche, L. Lärm, H. Hüging, F. Ewert, F. Ewert

“…To respond to water deficit, maize had higher water uptake rate per unit root length and higher root segment conductance in the stony soil than in the silty soil, while the crop reduced transpired water via reduced aboveground plant size. …”
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Features of the daily blood pressure in patients with ischemic chronic heart failure and renal dysfunction by V. D. Syvolap, D. A. Lashkul

“…Decreased GFR in patients with ischemic heart failure was associated with more senior age (p<0.0001), functional class of heart failure (p=0.02). More common history of hypertension (p=0.04). …”
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Low blood levels of selenium, selenoprotein P and GPx3 are associated with accelerated biological aging: results from the Berlin Aging Study II (BASE-II) by Valentin Max Vetter, Kamil Demircan, Jan Homann, Thilo Samson Chillon, Michael Mülleder, Orr Shomroni, Elisabeth Steinhagen-Thiessen, Markus Ralser, Christina M. Lill, Lars Bertram, Lutz Schomburg, Ilja Demuth

“…Results Participants with deficient serum selenium levels (< 90 μg/L) had a higher rate of biological aging (DunedinPACE, β = − 0.02, SE = 0.01, 95% CI − 0.033 to − 0.004, p = 0.010, n = 865). …”
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Vaimse heaolu komponendid muusikuks kujunemise teel. Toimetulek esinemisärevuse ja vaimsete blokkidega Eesti Muusika- ja Teatriakadeemia viiuli-, vioola- ja klaveritudengite hulgas... by Jelizaveta Bukina, Janika Mesi, Marju Raju

“…Mesi (2023) found that all violin and viola students who participated had experienced excessive performance anxiety to some extent. …”
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Exploring potential therapeutic targets for colorectal tumors based on whole genome sequencing of colorectal tumors and paracancerous tissues by Yufan Sheng, Sen Niu, Da Li, Chunyuan Meng, Tong Wang

“…We verified its expression level and function by protein blotting, immunohistochemistry, and cell scratch and cell viability assays. …”
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Prevalence and factors influencing disability and cognitive impairment among empty nesters and non-empty nesters in Guangdong, China: a cross-sectional study by Jinhua Guo, Yi Yang, Lixia Lin, Yi Zhang, Tiemei Shen

“…Category 1 medications were an influential factor specific to cognitive impairment among empty nesters (OR: 1.564, 95% CI 1.072, 2.282; p &lt; 0.05); and coronary heart disease was an influencing factor specific to cognitive impairment among non-empty nesters (OR: 1.319, 95% CI 1.046, 1.663; p &lt; 0.05).ConclusionThe study indicated that empty nesters had a higher prevalence of disability and cognitive impairment than non-empty nesters. …”
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Association of depression in multiple sclerosis with fatigue, sleep disturbances, disability, and health-related quality of life: Outcomes of a cross-sectional study by E. Aparicio-Castro, A. Candeliere-Merlicco, C.M. Santa, R. Villaverde-González

“…Patients with depressive symptoms exhibited higher disability scores, longer ambulation times, worse cognitive function in the Symbol Digit Modalities Test, and poorer sleep quality. …”
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