Dual-site phosphorylation of the control of virulence regulator impacts group a streptococcal global gene expression and pathogenesis. by Nicola Horstmann, Miguel Saldaña, Pranoti Sahasrabhojane, Hui Yao, Xiaoping Su, Erika Thompson, Antonius Koller, Samuel A Shelburne

“…Similarly, isoallelic GAS strains that were either unable to be phosphorylated at D53 (CovR-D53A) or had functional constitutive phosphorylation at T65 (CovR-T65E) had essentially an identical gene repression profile to each other and to a CovR-inactivated strain. …”
Get full text

Bioprospecting the Rodriguan Lime (Citrus aurantifolia Swingle) as a Novel Source of Antioxidants and Antimicrobials for Food Application by Liza Cloete, Anton Venter, Mohammad Naushad Emmambux, Deena Ramful-Baboolall, Brinda Ramasawmy, Swaleha Hudaa Neetoo, Carene Picot-Allain, Kwaku Gyebi Duodu

“…Given its broad antimicrobial spectrum and diverse phytochemicals, the Rodriguan lime extract shows potential for applications in the functional food and nutraceutical industries.…”
Get full text

Influence of PEEK surface modification with titanium for improving osseointegration: an in vitro study by Monika Saini, Jyoti Paliwal, Vineet Sharma, Neha Gupta, Kamal Kumar Meena, Parul Singhal

“…The cell adhesion test showed that NGP had the highest number of adhered cells, followed by NG, AGP, AG, and CG. …”
Get full text

Compositional and structural characterization of bioenergy digestate and its aerobic derivatives compost and vermicompost by Elisabetta Loffredo, Danilo Vona, Carlo Porfido, Maria Michela Giangregorio, Antonio Gelsomino

“…Results TXRF analysis showed that DG had the highest K content (~8.9 g kg−1), while VC had the maximum P, S and Ca contents, and appreciable levels of essential plant micronutrients, such as Mn, Fe, Cu and Zn. …”
Get full text

Insectivorans (Lipothyphla) of Left-bank Ukraine and Crimea: analytical materials on fauna and ecology by Igor Evstafiev, Igor Zagorodniuk

“…The Dnipro ecological corridor, which had functioned for many millennia, was completely destroyed in the 20th century due to the construction of a cascade of hydroelectric power plants and reservoirs. …”
Get full text

Cumulative dissipated energy during phacoemulsification is associated with bleb failure in eyes with prior trabeculectomy by Amer Mosa Alwreikat, Cansu Yüksel Elgin, David J. Ramsey, Paul R. Cotran

“…Bleb failure was defined as an eye that required the addition of two or more glaucoma medications or had an IOP > 21 mmHg at any follow-up visit more than one month after surgery. …”
Get full text

Mid- to Long-Term Outcomes of Cervical Disc Arthroplasty versus Anterior Cervical Discectomy and Fusion for Treatment of Symptomatic Cervical Disc Disease: A Systematic Review and... by Yan Hu, Guohua Lv, Siying Ren, Daniel Johansen

“…Patients after an ACDF had a significantly lower rate of follow-up than that after CDA. …”
Get full text

Promiscuous Recognition of a Trypanosoma cruzi CD8+ T Cell Epitope among HLA-A2, HLA-A24 and HLA-A1 Supertypes in Chagasic Patients. by Paola Lasso, Lina Beltrán, Fanny Guzmán, Fernando Rosas, M Carmen Thomas, Manuel Carlos López, John Mario González, Adriana Cuéllar, Concepción J Puerta

“…All patients tested had TcTLE-specific CD8+ T cells with frequencies ranging from 0.07-0.37%. …”
Get full text

Our First experience of Using Biodegradable Implants in Latarjet – Bristow Surgical Procedure at Chronic Posttraumatic Anterior Shoulder Insta by V. A. Monastyrev, M. E. Puseva, N. S. Ponomarenko

“…We registered strong functioning of an arm and an increase in the range of motions. …”
Get full text

Differences in gut microbial diversity and composition between growth phenotypes of farmed juvenile sandfish, Holothuria scabra by Joselito A. Tabardillo, Marie Antonette Juinio-Meñez, Adam M. Reitzel, Rachel Ravago-Gotanco

“…Gut microbiota of large juveniles had lower bacterial diversity than its smaller counterparts. …”
Get full text

Quality of life: predictors and outcomes after stroke in a Brazilian public hospital by Camila Thieime Rosa, Marise Bueno Zonta, Marcos Christiano Lange, Viviane de Hiroki Flumignam Zétola

“…Background Some scales are applied after stroke to measure functional independence but qualify of life (QoL) is sometimes neglected in this scenario. …”
Get full text

Validation of the Clinical Assessment Scale in Autoimmune Encephalitis in Chinese Patients by Yingchi Zhang, Ewen Tu, Chenxiao Yao, Jia Liu, Qiang Lei, Wei Lu

“…The CASE scores of patients receiving second-line treatment were significantly higher (median CASE: 15) than in those receiving first-line treatment (median CASE: 8) (p<0.001). Twenty-two patients had poor functional status (mRS>2). Areas under the curve of CASE on whether functional status was poor at 1 year were 0.89 (p<0.001). …”
Get full text

Personification of the tactics of the treatment of pseudoarthrosis of long bones, taking into account the previous stages of the treatment and a comorbidity by O. A. Kaplunov, S. A. Demkin, K. O. Kaplunov, E. Y. Nekrasov

“…The paper presents two clinical cases demonstrating modern approaches and possibilities of personification of the therapeutic tactics of surgical rehabilitation of patients with defect-pseudoarthrosis of long bones. Both patients had a complex comorbid status and had previously been operated on repeatedly without success. …”
Get full text

The understanding of digital communication experts and oral cancer at-risk persons on oral cancer, their uptake of educational mobile health applications on oral cancer, and their... by Kehinde Kazeem Kanmodi, Yovanthi Anurangi Jayasinghe, Ruwan Duminda Jayasinghe, Success Onuoha, Jimoh Amzat, Afeez Salami, Misheck Nkhata, Lawrence Achilles Nnyanzi

“…Results Some participants had misconceptions on oral cancer. Although, majority of them opined that MHA will be useful in improving literacy on oral cancer, but none of them had ever used an educational MHA on oral cancer before. …”
Get full text

Impact of topical cetylated fatty acid cream on hand osteoarthritis: a randomized, double-blind clinical trial by Sitthiphong Suwannaphisit, Nitiphoom Sinnathakorn, Pormes Suwanno, Warangkana Fongsri, Boonsin Tangtrakulwanich

“…Eligible patients were over 40 years of age, had at least one tender joint, and had a joint pain visual analog score of 30–60 mm. …”
Get full text

Candidate genes associated with fatty acid compositions in north American Atlantic salmon (Salmo salar) by Barbara L. Langille, Manuel Juárez, Nuria Prieto, Solomon Boison, Panya Sae Lim, Bruce D. Swift, Amber F. Garber

“…These genes, fads2 in particular, would all make ideal candidates for future functional studies. In addition, there were four fatty acids with loci over the suggestive significant threshold with a variety of markers on different chromosomes (lauric acid, stearic acid, eicosatetraenoic acid (ETA), and docosadienoic acid), with associated genes that had relevant functions to fatty acids or adipose cells in general.…”
Get full text

Emotional Experience and Consequences of Growing Up in a Family with Alcoholism in Adult Children of Alcoholics by Barbara Simonič, Elżbieta Osewska

“…Adult children of alcoholics often have problems in experiencing and regulating their emotions, as they had to carry many emotional burdens in a dysfunctional family, while they had no real opportunity for the healthy development of emotional regulation. …”
Get full text

Phenolics from grapefruit peels inhibit HMG-CoA reductase and angiotensin-I converting enzyme and show antioxidative properties in endothelial EA.Hy 926 cells by Ayokunle O. Ademosun, Ganiyu Oboh, Sabina Passamonti, Federica Tramer, Lovro Ziberna, Aline Augusti Boligon, Margareth Linde Athayde

Get full text

Early clinical evaluation of the Hugo robotic-assisted surgery (RAS) for performing radical prostatectomy: an IDEAL stage 2 study by Prokar Dasgupta, Ben Challacombe, Andrew Shepherd, Ata Jaffer, Angus Bruce, Daniel Chia

“…On final pathology, 18 patients (36%) had T3 disease and four had positive surgical margins (8%). …”
Get full text

Evaluation of quality of life in type-2 diabetes with other comorbid conditions: a cross-sectional study by Sreya Kosanam, Nithya Varadarajan, Aman Suresh Tharayil, Hari Chandana Varikallu, M. Sai Sruthi

“…The QoL in patients with diabetes alone was higher (54.26%) than that in patients with diabetes and kidney disease (53.21%), diabetes with hypertension (52.16%), and diabetes with thyroid (43.16%), whereas diabetes with cancer had a very low QOL (39.5%). Conclusion According to 8 parameters included in SF 36, diabetes patients have high Quality of Life (QOL) (54.26%) in Physical functioning (PF), role-physical (RP), bodily pain (BP), general health (GH), vitality (VT), social functioning (SF), role-emotional (RE), and mental health (MH). …”
Get full text