Impact of aging on gene expression in human oocytes: a comparative analysis of young and older patients by Raoul Orvieto, Omri Nayshool, Louisa Cohen, Yuval Yung, Adva Aizer, Efrat Glick Saar, Dan Dominissini

“…These genes underscore the impact of aging on critical oocyte pathways, including chromosomal stability, epigenetic regulation, mitochondrial function, immune response, structural integrity, and calcium signaling. …”
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Effects of low wildfire burn severity due to pre-fire shrub thinning on the chaparral soil bacteriome in the Santa Monica Mountains of Southern California by Mariah Macias, Mari R. Irving, Katelyn M. Bandow, Kaitlyn Kim, Cecilia Heredia, Courtney A. Hoskinson, Nina R. Duchild, Michael T. Nicholas, Lindsey M. Marian, Camille K. Sicangco, Karagan L. Smith, Stephen D. Davis, Helen I. Holmlund, Leah T. Stiemsma

“…ABSTRACT Our objective was to study the longitudinal effect of decreased burn severity due to vegetation-type conversion (VTC) induced by chaparral shrub thinning prior to the Woolsey wildfire (November 2018) on soil chemistry and bacteriome composition and function. We compared soils from two study sites on the Malibu campus of Pepperdine University in the Santa Monica Mountains: one site had dense, unaltered chaparral shrubland and experienced a 4.5-fold increase in vegetation burn severity (high severity burn) compared to an adjacent altered site where the vegetative fuel load was 80% less prior to the fire (low severity burn). …”
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Clinical predictors of 3-month isoniazid rifapentine (3HP)-related adverse drug reactions (ADR) during tuberculosis preventive therapy (PAnDoRA-3HP study): an observational study p... by Turyahabwe Stavia, Barbara Castelnuovo, Christine Sekaggya-Wiltshire, Kelly E Dooley, Grace Banturaki, Irene Mbabazi, Ruth Mirembe Nabisere, Lucy Alinaitwe, Brian Otaalo, Florence Aber, Juliet Nampala, Rogers Owori, Josephine Bayigga, Jonathan Mayito, Eva Agnes Odongpiny Laker, Moorine Penninah Sekadde, Jotam Pasipanodya, Stella Zawedde‐Muyanja

“…We enrolled consecutive patients who had been initiated on TPT using the 3HP regimen. …”
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Type 2 diabetes mellitus’ impact on heart failure patients’ exercise tolerance: a focus on maximal fat oxidation during exercise by Huiying Zhu, Huiying Zhu, Jianchao Pan, Jianxuan Wen, Jianxuan Wen, Xiaojing Dang, Xiaojing Dang, Xiankun Chen, Xiankun Chen, Yunxiang Fan, Yunxiang Fan, Weihui Lu, Weihui Lu, Wei Jiang, Wei Jiang

“…In addition, the T2DM group had lower FATox at exercise intensity levels of 40% (P < 0.05) and 50% (P < 0.05) of peak VO2, compared to the non-T2DM group.ConclusionsT2DM is associated with a decrease in exercise tolerance and fat oxidation capacity in patients with heart failure. …”
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Artificial intelligence-based spatial analysis of tertiary lymphoid structures and clinical significance for endometrial cancer by Haruka Suzuki, Kohei Hamada, Junzo Hamanishi, Akihiko Ueda, Ryusuke Murakami, Mana Taki, Rin Mizuno, Koichi Watanabe, Hanako Sato, Yuko Hosoe, Hiroaki Ito, Koji Yamanoi, Hiroyuki Yoshitomi, Nobuyuki Kakiuchi, Ken Yamaguchi, Noriomi Matsumura, Seishi Ogawa, Hideki Ueno, Masaki Mandai

“…Moreover, patients with dTLSs had a higher response rate to immune checkpoint inhibitors (87.5 vs. 41.7%) and a trend toward improved PFS. …”
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Effects of Three Different Bee Pollen on Digestion, Immunity, Antioxidant Capacity, and Gut Microbes in <i>Apis mellifera</i> by Xin-Meng Li, Ying Wang, Li Lei, Ge Zhang, Bao-Hua Xu

“…In summary, honeybees had the worst digestibility of Sunflower bee-collected pollen; sunflower bee pollen had a greater effect on antioxidant and immune functions, and intestinal flora of honeybees. …”
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Viral dynamics and factors associated with duration of COVID-19 positivity: evidence from the first-three epidemiological waves in Cameroon by Joseph Fokam, Aurelie Minelle Kengni Ngueko, Alex Durand Nka, Collins Ambe Chenwi, Ezechiel Ngoufack Jagni Semengue, Yagai Bouba, Désiré Takou, Nadine Fainguem, Michel Carlos Tommo Tchouaket, Aude Christelle Ka’e, Grace Angong Beloumou, Sandrine Claire Djupsa Ndjeyep, Willy Leroi Togna Pabo, Davy-Hyacinthe Gouissi Anguechia, Naomi-Karell Etame, Evariste Molimbou, Rachel Audrey Nayang Mundo, Aissatou Abba, Samuel Martin Sosso, John Otshudiema Otokoye, Christian Ngongang Ouankou, Claudia Alteri, Luna Colagrossi, Maria-Mercedes Santoro, Francesca Ceccherini-Silberstein, Yap Boum, Edie Gregory Halle Ekane, Alfred K. Njamnshi, Vittorio Colizzi, Nicaise Ndembi, Alexis Ndjolo, Carlo-Federico Perno

“…The mean age was 41 ± 14 years, with male predominant (62.1%). We had 15.6% symptomatic participants of which 59% had cough. …”
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Transplant of Induced Pluripotent Stem Cell–Derived Retinal Pigment Epithelium Strips for Macular Degeneration and Retinitis Pigmentosa by Daiki Sakai, MD, Michiko Mandai, MD, PhD, Yasuhiko Hirami, MD, PhD, Midori Yamamoto, BA, Shin-ichiro Ito, MD, PhD, Saori Igarashi, MD, Satoshi Yokota, MD, PhD, Hirofumi Uyama, MD, PhD, Masashi Fujihara, MD, PhD, Akiko Maeda, MD, PhD, Motoki Terada, BS, Mitsuhiro Nishida, MS, Yumiko Shibata, MS, Naoko Hayashi, MS, Kyoko Iseki, MA, Takuya Miura, MS, Keisuke Kajita, MD, PhD, Masaaki Ishida, MD, PhD, Sunao Sugita, MD, PhD, Tadao Maeda, MD, PhD, Masayo Takahashi, MD, PhD, Yasuo Kurimoto, MD, PhD

“…Participants: Three eyes from 3 patients clinically diagnosed with RPE impairment disease; 1 patient had dry age-related macular degeneration (AMD), and remaining 2 patients had MERTK-associated retinitis pigmentosa. …”
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Chronic lung lesions in COVID-19 survivors: predictive clinical model by Paulo A Lotufo, Juliana C Ferreira, Eloisa Bonfa, Anna S Levin, Rodrigo Caruso Chate, Marta Imamura, Esper G Kallas, Roger Chammas, Thais Mauad, Izabel Marcilio, Nelson Gouveia, Ricardo Nitrini, José Eduardo Krieger, Marcio Valente Yamada Sawamura, Michelle Louvaes Garcia, Cristiano Gomes, Guilherme Fonseca, Jorge Hallak, Luis Yu, Marcio Mancini, Maria Elizabeth Rossi, Thiago Avelino-Silva, Edivaldo M Utiyama, Aluisio C Segurado, Beatriz Perondi, Anna Miethke-Morais, Amanda C Montal, Leila Harima, Marjorie F Silva, Marcelo C Rocha, Maria Amélia de Jesus, Carolina Carmo, Clarice Tanaka, Julio F M Marchini, Thaís Guimarães, Ester Sabino, Carlos Roberto Ribeiro Carvalho, Celina Almeida Lamas, Diego Armando Cardona Cardenas, Daniel Mario Lima, Paula Gobi Scudeller, João Marcos Salge, Cesar Higa Nomura, Marco Antonio Gutierrez, Adriana L Araújo, Bruno F Guedes, Carolina S Lázari, Cassiano C Antonio, Claudia C Leite, Emmanuel A Burdmann, Euripedes C Miguel, Fabio R Pinna, Fabiane Y O Kawano, Geraldo F Busatto, Giovanni G Cerri, Heraldo P Souza, Izabel C Rios, Larissa S Oliveira, Linamara R Batisttella, Luiz Henrique M Castro, Marcello M C Magri, Maria Cassia J M Corrêa, Maria Cristina P B Francisco, Maura S Oliveira, Orestes V Forlenza, Ricardo F Bento, Rodolfo F Damiano, Rossana P Francisco, Solange R G Fusco, Tarcisio E P Barros-Filho, Wilson J Filho

“…Almost half of them (48%) had significant pulmonary abnormalities, including ground-glass opacities, parenchymal bands, reticulation, traction bronchiectasis and architectural distortion. …”
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EFFECT OF ROSUVASTATIN ON CAROTID INTIMAMEDIA THICKNESS IN PATIENTS WITH CORONARY ARTERY DISEASE OF DIFFERENT GENDER AND CARDIOVASCULAR RISK PROFILE by S. I. Kononov, G. S. Mal

“…Materials and methods. 72 patients with CAD: Stable angina of functional Classes II–III were recruited. They were treated with rosuvastatin, with gradual increase of its dose from 5 to 40 mg daily to attain target levels of TC and LDL-C. …”
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Perioperative anesthetic management in total abdominal hysterectomy due to uterine fibroid in a patient with severe aortic stenosis. A case report by Yuliel Varona Rodríguez, José Carlos Acosta Abad, Adonis Cintra Dornes, Liliam María Castillo Manresa

“…The echocardiographic examination showed that the patient had severe aortic stenosis with preserved ejection fraction, stress test: functional class I, without ischemia. …”
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Enhancing grape juice with Lacticaseibacillus rhamnosus CWKu-12: Assessing probiotic viability, physicochemical changes, sensory characteristics, and quality kinetics throughout st... by Shaghayegh Echresh, Behrooz Alizadeh Behbahani, Fereshteh Falah, Mohammad Noshad, Salam A. Ibrahim

“…Moreover, grape juices that had been cold-stored and added probiotics had the highest level of sensory acceptance. …”
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Comparative analysis of milk production, composition, and plasma metabolomics across various dairy goat breeds in Yunnan Province, China by Xun Xiang, Hua Chang, Samiullah Khan, Ibrar Muhammad Khan, Feiyan Zhu, Linfu Yang, Gang Duan, Jiming Li, Nourhan Nassar, Feiyan Dai, Huaming Mao

“…On day 120, AYF1 goats had higher fat content, while Saanen goats had higher protein content compared to Toggenburg goats. …”
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Sarcopenia and its associated factors among hip fracture patients admitted to a North African (Egyptian) Level one trauma center, a cross-sectional study by Dalia G Mahran, Ahmed A. Khalifa, Abdelhafeez Hamdi Abdelhafeez, Osama Farouk

“…Conclusion The sarcopenia prevalence in our hip fracture patients was 17%, where BMI, fat mass, and nutritional status had a significant negative association; on the other hand, the sum of SARC-F (≥ 4 points) had a significant positive association. …”
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EFFECTIVENESS OF SILICONE MATERIALS IN PREVENTING PATHOLOGICAL SCARS IN MAXILLO-FACIAL AREA by R.Z. Ohonovskyi, H.O. Loza, Y.P. Nahirnyi

“… Pathological scars are not only an integral medical and aesthetic problem nowadays, but also serious functional and aesthetic consequences of traumatic and surgical wounds. …”
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Enrichment of tandem repeat element variants near CHD genes identified by short- and long-read genome sequencing by Abhilash Suresh, Sarah U. Morton, Daniel Quiat, Steven R. DePalma, Joshua M. Gorham, Martina Brueckner, Martin Tristani-Firouzi, Bruce D. Gelb, Jonathan G. Seidman, Christine E. Seidman, the Pediatric Cardiac Genomics Consortium

“…Many individual TR element variants were in known regulatory regions, but further work is needed to determine their functional impact.…”
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Ellenreformáció, felvilágosodás, állami erőkoncentráció-optimalizálás? Heinrich Kajetan Blümegen grófjának bevonása az erdélyi vallásügyek főfelügyeletébe 1763–64-ben... by Kálmán Árpád KOVÁCS

“…The House, Court, and State Archives has functioned as the most important depository for court-related subjects since Kaunitz’s founding of the Council of State. …”
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Value of transoesophageal echocardiography-guided approach to electrical cardioversion of atrial fibrillation by O. S. Kalashnikovа

“…No one had thrombi identification in atrial chambers. Spontaneous echocontrast was detected in all patients. …”
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Evaluation of the relationship between cytochrome P450 (CYP) 1A2 gene copy number variation and CYP1A2 protein content and enzyme activity in canine liver by Francisco Gonzales Zamora, Hannah Bigelow, Hong Yang, Tania Perez Jimenez

“…Among the 58 liver samples genotyped for CYP1A2 CNV, nine dogs had two copies, 20 had three copies, 23 had four copies, and six had five copies. …”
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Prevalence, Activity Limitations and Quality of Life in Patients with Non-Specific Neck Pain in Burundi: A Cross-Sectional Study by Ndacayisaba G, Ndayishima B, Mapinduzi J, Ndayishimiye P, Sinzakaraye A, Van Cant J

“…A minority had poor health-related quality of life (20.60%). …”
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