Effectiveness of different treatment regimens of enhanced external counterpulsation in patients with stable coronary artery disease complicated by heart failure by A. S. Lishuta, O. A. Slepova, N. A. Nikolaeva, N. V. Khabarova, E. V. Privalova, Yu. N. Belenkov

“…Correlation analysis and risk assessment of adverse events (combined endpoint — combination of cases of adverse cardiovascular events, deaths, hospitalizations for CHF, new-onset of atrial fibrillation, diabetes, decreased renal function) was performed.Results. Treatment effectiveness had positive correlation with EECP duration (r(S)=0,670; p<0,001) and treatment regimen (r(S)=0,620; p<0,001). …”
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Clinical characteristics and risk factors of bacillary layer detachment in central serous chorioretinopathy: a comparative multicenter study by Antonio M. Casella, Raphaela M. Fuganti, Ahmad M. Mansour, José Ignácio Fernández-Vigo, Suthasinee Sinawat, Ali Osman Saatci, Jay Chhablani, Arman Zarnegar, Juliana Prazeres, Igor Kozak, Lorenzo López Guajardo, Michel E. Farah, Claudio Zett, Francisco Rodriguez, William E. Smiddy, Janet L. Davis, Philip J. Rosenfeld, Stephen G. Schwartz, Luiz H. Lima, Maurício Maia

“…Results Thirty-seven patients (40 eyes; mean age, 48.0 ± 11.9 years) had CSC and BALAD and were followed for a mean of 4.92 ± 6.65 months. …”
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Prevalence of chronic obstructive pulmonary disease in high-risk populations at low, intermediate, high altitudes: a population based cross-sectional study in Yunnan Province, Chin... by Geyi Wen, Jinliang Meng, Huadan Wang, Puxian Peng, Yanyan Xu, Ruiqi Wang, Zhengmao Yan, Bangyan Du, Aihan Wen, Guohong Luo, Wenlong Cui, Songyuan Tang, Yunhui Zhang

“…COPD patients in high-risk populations at high-altitude areas had a higher prevalence of ethnic minorities and significant biomass fuel exposure. …”
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A Chinese pediatric patient with thalassemia traits and compound heterozygous mutations in the PIEZO1 gene suspected of having dehydrated hereditary stomatocytosis by Weijie Chen, Xinyu Li, Huaqing Yang, Chao Niu, Yushan Huang, Lang Qin, Mingyan Fang, Shaofen Lin, Kaimei Wang, Yuan Zhuang, Yuhua Ye, Xin Jin, Jianpei Fang, Xiangmin Xu, Ke Huang, Honggui Xu

“…Background Dehydrated Hereditary Stomatocytosis (DHS), also known as Hereditary Xerocytosis (HX), is a rare genetic disorder primarily arising from gain-of-function mutations in PIEZO1, which disrupt mechanosensitive ion channels on red blood cell membranes. …”
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Effect of Sensory Integration Therapy on Attention Span and Gross Motor Skills in Children with Down Syndrome: A Quasi-experimental Study by Manshi Baberwal, Dimple Choudhry, Anjali, Anshu Kumari, Mallika Jhandai, Pankaj Bhardwaj, Ekta

“…Attention span was measured using Stroop colour and Word Test and gross motor skills were measures with the help of {Gross Motor Function Measure 88 (GMFM-88)}. The data was analysed with the help of independent t-test (for between-group analysis) and repeated measures Analysis of Variance (ANOVA) (for within-group analysis). …”
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Association of pituitary neuroendocrine tumors and neurofibromatosis type 1: assessing causation versus coincidence. Case report by Mercedes Aguilar-Soto, Julia M. Zuarth-Vázquez, Laura Leyva-Figueroa, Karla Zarco-Ávila, Armando Gamboa-Domínguez, Aldo Eguiluz-Melendez, Laura C. Hernández-Ramírez

“…Similar cases were searched in the literature.ResultsA 54-year-old-man was incidentally diagnosed with a clinically non-functioning PitNET via brain imaging. He had a personal and family history of NF1 and carried the germline pathogenic variant NF1 (NM_001042492.3): c.147C>A, p.Y49*. …”
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Integrative multi-omics analysis reveals the interaction mechanisms between gut microbiota metabolites and ferroptosis in rheumatoid arthritis by Lifang Liang, Lifang Liang, Lifang Liang, Huaguo Liang, Min He, Min He, Min He, Huiling Zhang, Huiling Zhang, Huiling Zhang, Peifeng Ke, Peifeng Ke, Peifeng Ke

“…Additionally, molecular docking analysis of GPX3 and MYC with the gut metabolites Diosgenin and Differentiation-inducing factor 3 (DIF-3) respectively showed that the GPX3-Diosgenin complex had the lowest binding energy, and a 100 ns molecular dynamics simulation was performed on this complex. …”
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Preliminary Study on the Single Nucleotide Polymorphism (SNP) of XRCC1 Gene Identificationto Improve the Outcomes of Radiotherapy for Cervical Cancer by Devita Tetriana, Wiwin Mailana, Iin Kurnia, Mukh Syaifudin

“…Additionally, structure and function of this protein can be altered by functional SNPs, which may lead to the susceptibility of individuals to cancers. …”
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The association and impact of radiographic, pathological emphysema and spirometric airway obstruction on patients with resectable lung adenocarcinoma by Yixiao Zhang, Lu Lang, Xiaojuan Guo, Kewu Huang, Jiawen Yi, Yuan Yuan, Min Zhu, Shu Zhang, Bin Hu, Xue Li, Yuhui Zhang

“…Abstract Background Destruction of alveoli structure and lung function are interrelated, however, their correlation and clinical significance have been not well defined in patients with lung cancer. …”
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Development and Validation of a Machine Learning Model for Predicting Long-Term Depression Risk in ACS Patients After PCI: A Retrospective Cohort Study by Lv H, Sun F, Zhang Y, Zhou X

“…These models used routine clinical information like heart function, thyroid levels, and diabetes status to make predictions.The results showed that about 1 in 5 patients developed depression. …”
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Machine learning for detection of diffusion abnormalities-related respiratory changes among normal, overweight, and obese individuals based on BMI and pulmonary ventilation paramet... by Xin-Yue Song, Xin-Peng Xie, Wen-Jing Xu, Yu-Jia Cao, Bin-Miao Liang

“…Methods We conducted a retrospective analysis of data from 440 individuals who underwent pulmonary function tests between January 1, 2021, and April 1, 2024. …”
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The construction and evaluation of a prognostic risk score model for HCC based on MPT-related lncRNAs by Zerun Lin, Jianda Yu, Zhijian Chen, Jingyi Chen, Xiaobin Chi, Honghuan Lin, Yongbiao Chen, Yongbiao Chen

“…Combined with immune cell infiltration and immune function scores, these results showed that the patients in the low-risk group had a more significant clinical response to immunotherapy (p < 0.05). …”
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Novel Gels for Post-Piercing Care: Evaluating the Efficacy of Pranoprofen Formulations in Reducing Inflammation by Negar Ahmadi, Maria Rincón, Mireia Mallandrich, Joaquim Suñer-Carbó, Lilian Sosa, Mireya Zelaya, Sergio Martinez-Ruiz, Cecilia Cordero, Ana C. Calpena

“…All gels had similar spreadability with PF-Gel-Lut showing the highest. …”
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Efficacy and safety of interferon alfa-2b in the complex therapy of patients with chronic bacterial prostatitis: a multicenter randomized clinical trial by Kh. S. Ibishev, M. I. Kogan, V. V. Dubensky, Vl. V. Dubensky, I. S. Shormanov, A. S. Soloviev, I. V. Bazhenov, D. V. Romanenko, E. N. Vyzhlova

“…Chronic bacterial prostatitis reduces the reproductive function of men and worsens the quality of life. Impairment of the immune system in chronic bacterial prostatitis requires immunocorrection and use of additional immunomodulatory therapy. …”
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Investigating the risks of late preterm and term neonatal morbidity across clinical subtypes of intrahepatic cholestasis of pregnancy by Wei-Zhen Tang, Wei-Zhen Tang, Yi-Fan Zhao, Lan Wang, Qin-Yu Cai, Qin-Yu Cai, Wei-Ze Xu, Li Wen, Xue-Bing Chen, Ting-He Sheng, Ting-He Sheng, Tian-Qi Fan, Tai-Hang Liu, Rong Li, Shang-Jing Liu

“…In addition, the ICP-M exhibited higher liver function and blood glucose levels. The ICP-M was significantly associated with increased risks of gestational diabetes mellitus (GDM) (OR 1.57), preterm birth (OR 1.92), low-birth-weight infant (OR 1.81), and neonatal intensive care unit (NICU) admissions (OR 1.48) than the ICP-S. …”
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Calcitriol and Tacalcitol Modulate Th17 Differentiation Through Osteopontin Receptors: Age-Dependent Insights from a Mouse Breast Cancer Model by Strzykalska-Augustyniak A, Psurski M, Zachary H, Filip-Psurska B, Kłopotowska D, Milczarek M, Świtalska M, Stachowicz-Suhs M, Łabędź N, Ziemblicka A, Gos M, Wietrzyk J

“…CD29 promoted IL-17 expression in tacalcitol-treated mice, while CD51 and CD44 had opposing effects. CD51 blockade reduced IFNγ+ Th17 cells in both treatment groups. …”
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Challenges to creating primary care teams in a public sector health centre: a co-operative inquiry by Bob Mash, Pat Mayers, Hoffie Conradie, Abraham Orayn, Marjan Kuiper, Joey Marais, Bennie Cornelissen, Shaamelah Titus

“…Enhanced practitioner-patient relationships were reported by the two teams that had staff consistently available. Significant changes in the behaviour and roles of staff. …”
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Renal drug dosing practices and clinical outcomes in patients with kidney disease admitted at two referral hospitals in Northwest Ethiopia by Gebeyaw Addis Bezie, Meseret Adugna, Gizachew Tadesse Wassie

“…Patients with any degree of renal disease are at risk of drug metabolism and excretory function loss. Toxicity from lack of proper drug or metabolite excretion and ineffective dosing from renal adjustment likely affects the clinical outcome of critical patients among other factors. …”
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Preparation of nanosized hypoxia-inducible factor 1α inhibitor and its application in reversing chemoresistance in colorectal cancer cells by ZHENG Chuanhao, DAN Ruijue, XI Xi

“…Methods‍　‍Nano-inhibitor mPEG350-YC-1 (MYC-1) was prepared by the carboxyl condensation reaction of the active functional group hydroxyl (-OH) in the YC-1 molecule with methoxy polyethylene glycol carboxylic acid, and was verified by 1H nuclear magnetic resonance (1H-NMR). …”
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Contrasting effects of Si on high-temperature deformation behavior and room-temperature strength in V-microalloyed 10Mn-18Cr stainless steels by Atef Hamada, Ali Khosravifard, Khaled Elanany, Mahmoud Khedr, Anna Kisko, Matias Jaskari, Saad Ebied, Tarek Allam, Antti Järvenpää, Pentti Karjalainen

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