Prediction-based prompt levothyroxine replacement to prevent a hypothyroid state after immune-related adverse events involving the thyroid gland by Ichiro Yamauchi, Takuro Hakata, Taku Sugawa, Daisuke Kosugi, Haruka Fujita, Kentaro Okamoto, Yohei Ueda, Toshihito Fujii, Daisuke Taura, Norio Harada, Nobuya Inagaki

“…The Toxic-Hypo group developed thyroid irAEs earlier than the Toxic group (26 vs. 91 days; p < 0.001), and had higher serum free T4 levels (3.210 vs. 1.880 ng/dL; p = 0.011). …”
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Case report: Duplication of the GCK gene is a novel cause of nesidioblastosis: evidence from a case with Silver-Russell syndrome-like phenotype related to chromosome 7 by Takashi Shoji, Ichiro Yamauchi, Hidenori Kawasaki, Kogoro Iwanaga, Takuro Hakata, Daisuke Tanaka, Junji Fujikura, Toshihiko Masui, Hisato Suzuki, Mamiko Yamada, Kenjiro Kosaki, Yosuke Kasai, Etsuro Hatano, Akira Inaba, Takahito Wada, Shinji Kosugi, Yohei Ueda, Toshihito Fujii, Daisuke Taura, Nobuya Inagaki

“…We determined that the patient had SRS-like phenotype based on his clinical features and this duplication. …”
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Individuals Frequently Search Google With Questions About the Management of Meniscal Tears and the Indications for and Technical Details of Surgery but the Quality of the Informati... by Jonathan Spaan, M.S., John Streepy, M.S., Alexander Hodakowski, M.D., Amelia Hummel, M.D., Colton Mowers, B.S., Sabrina Schundler, B.S., Johnathon R. McCormick, M.D., Jonathan Riboh, M.D., Dana Piasecki, M.D., Jorge Chahla, M.D., Ph.D.

“…Methods: This study used Google’s People Also Ask function to extract the most common 300 questions and associated Web pages regarding meniscal tears and meniscal surgery. …”
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A longitudinal cohort study on dispensed analgesic and psychotropic medications in older adults before, during, and after the COVID-19 pandemic: the HUNT study by Tanja Louise Ibsen, Ekaterina Zotcheva, Sverre Bergh, Debby Gerritsen, Gill Livingston, Hilde Lurås, Svenn-Erik Mamelund, Anne Marie Mork Rokstad, Bjørn Heine Strand, Richard C. Oude Voshaar, Geir Selbæk

“…People without dementia had increased prescriptions of opioids, other analgesics, and antidepressants after lockdown, whereas no changes were observed among those with dementia. …”
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Effects of Environmental pH on the Growth of Gastric Cancer Cells by Wenjie Li, Ying Zhou, Chunyu Shang, Hui Sang, Hong Zhu

“…Some studies have found that PPI had a certain antitumor effect in the proliferation and apoptosis of tumor cells. …”
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Feasibility and safety of regadenoson stress perfusion protocol in pediatric transplant patients under general anesthesia by Nikkan Das, Eric L. Vu, Andrada Popescu, Defne Magnetta, Cynthia K. Rigsby, Joshua D. Robinson, Simon Lee, Nazia Husain

“…Background: Cardiovascular magnetic resonance with myocardial stress perfusion (stress CMR) is a non-invasive technique that offers an assessment of myocardial function, perfusion, and viability. Regadenoson is a selective cardiac adenosine A2 receptor agonist with fewer side effects than adenosine and a favorable safety profile in older pediatric heart transplant recipients (PHTR). …”
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Analytical methods for assessing the quality of sugarcane bagasse compost and improving the physicomechanical properties toward densification by Ehsan Sarlaki, Mohammad Hossein Kianmehr, Marzieh Ghorbani

“…Optimization results from D-optimal design showed that under optimum conditions of moisture content of 8 %w.b, 1-mm mesh opening size and rotational speed 1400 rpm of hammer-attrition mill, a minimum amount of SEC (141.38 KJ/Kg), and the maximum amount of bulk density (209.62 kg/m3) were introduced as optimum responses with the desirability function of 0.88.…”
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The relationship between perifoveal capillary ring alterations and visual acuity in diabetic retinopathy by Petrović Nenad, Todorović Dusan, Srećković Sunčica, Šarenac-Vulović Tatjana, Jovanović Svetlana, Paunović Svetlana, Vulović Dejan, Ranđelović Danijela

“…The location of macular ischemic changes in the nasal parts of the perifoveal capillary ring plays a crucial role in its effects on visual function.…”
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Nutrient Additions Regulate Height Growth Rate but Not Biomass Growth Rate of Alpine Plants Through the Contrasting Effect of Total and Available Nitrogen by Runfang Feng, Shu Wang, Jikui Ma, Nannan Wang, Xiaoli Wang, Fei Ren, Honglin Li, Defei Liang, Jing Hu, Xilai Li, Lanping Li

“…Plant growth, a fundamental biological process that underpins terrestrial ecosystem function, is susceptible to nutrient availability. …”
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Predicting the risk of left ventricular diastolic dysfunction in obesity by G. A. Chumakova, O. V. Gritsenko, O. V. Gruzdeva, A. V. Zateev

“…These groups had no differences in such parameters as high-density lipoprotein cholesterol (p=0,09) and glucose (p=0,12). …”
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Application of the DEB-TKTD model with multi-omics data: Prediction of life history traits of Chinese mitten crab (Eriocheir sinensis) under different salinities by Hanzun Zhang, Shipeng Dong, Hongwei Shan, Chao Yang, Fang Wang

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Postmenopausal women with higher TSH values within the normal range present improved handgrip strength: a pilot study by Panagiota Chatzivasileiou, Eleni Armeni, Peter Chedraui, Loraina Kontou, Areti Augoulea, Anastasia Palaiologou, George Kaparos, Konstantinos Panoulis, Andreas Alexandrou, Nikolaos Vlachos, Irene Lambrinoudaki

“…Objective To evaluate the possible association between thyroid function within the euthyroid range and musculoskeletal parameters as well as body composition in a sample of postmenopausal women.Methods This cross-sectional study included 96 postmenopausal women with serum thyroid-stimulating hormone (TSH) within the normal laboratory reference range. …”
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Prevalence and biological impact of clinically relevant gene fusions in head and neck cancers by Emily L. Hoskins, Raven Vella, Julie W. Reeser, Michele R. Wing, Eric Samorodnitsky, Altan Turkoglu, Leah Stein, Elizabeth Breuning, Zachary A. Risch, Wilnelly M. Hernandez-Sanchez, Lianbo Yu, Michelle Churchman, Nancy Single, Jad Chahoud, Antonio Jimeno, Michael J. Cavnar, Matthew Reilley, Courtney Scaife, Kenneth G. Nepple, Minh Phan, Bryan Schneider, Stephen Edge, Bodour Salhia, Aliza Leiser, Trisha M. Wise-Draper, Michael K. Wendt, Sameek Roychowdhury

“…We identified 66 cases (2.8%) harboring oncogenic fusions, including previously-reported FGFR3 fusions (n = 19) and gain-of-function EGFR fusions (n = 6). Fusion-positive HNC had significantly higher gene expression and higher prevalence of human papillomavirus than fusion-negative HNC (p < 0.001). …”
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Сhronic kidney disease complications in patients with type 1 diabetes mellitus after simultaneous pancreas-kidney transplantation – potential role of oxidative stress and glycation... by Irina I. Larina, Anastasia S. Severina, Minara S. Shamkhalova, Daria N. Egorova, Larisa V. Nikankina, Natalia I. Sazonova, Ilya V. Dmitriev, Aleksey V. Pinchuk, Michael M. Kaabak, Marina V. Shestakova

“…With vitamin D deficiency, observed in 80% of cases (13.3 [9.3; 18.5] ng/ml), 55% of patients had secondary hyperparathyroidism, 45% &ndash; osteoporosis. …”
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UK poSt Arthroplasty Follow-up rEcommendations (UK SAFE): what does analysis of linked, routinely collected national datasets tell us about mid–late term revision risk after knee r... by Andrew Judge, Sarah R Kingsbury, Nigel K Arden, Rafael Pinedo-Villanueva, Lindsay K Smith, Cesar Garriga, Antonella Delmestri, Martin Stone

“…CPRD GOLD-HES data covered 1995–2011 on 17 378 KR. Patients had minimum 5 years postprimary surgery to end 2016. …”
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Synergistic effect of corn straw and mulberry leaves on fermentation, growth performance and antioxidant capacity of sheep by Qirui Hou, Wenfeng Zhang, Shuli Wang, Wenyu Hou, Weiguo Zhao, Hui Xie, Peng Zhao, Yongen Zhang

“…Conclusion The combination of corn straw and mulberry leaves had a positive synergistic effect on improving feed intake, muscle thickness, muscle water retention, and the liver antioxidant capacity in sheep. …”
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Effect of Gamification on Improved Adherence to Inhaled Medications in Chronic Obstructive Pulmonary Disease: Randomized Controlled Trial by Xiting Huang, Zhili Jiang, Yifan Dai, Yang Liu, Ziying Dai, Jing Wang, Liping Chen, Zhiqian Wang, Wenxiao Wu, Lihua Huang

“…The generalized estimating equation showed that, compared to the control group, the Inhaling-Health website led to a gradual improvement in total adherence-to-inhaler scores starting from 2 months after the intervention (median 51.00, IQR 49.00-52.25 vs median 50.00, IQR 47.00-51.00; Z=–2.014; P=.04). It had a separate positive effect on inhaler technique. …”
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Comparative IP-MS Reveals HSPA5 and HSPA8 Interacting with Hemagglutinin Protein to Promote the Replication of Influenza A Virus by Xingwei Feng, Mengfei Ning, Bin Chen, Xuan Li, Honglei Sun, Juan Pu, Jinhua Liu, Na Wang, Yinhua Huang

“…We then focused on the function of two heat shock proteins (HSPA5 and HSPA8), which interacted with IAV HA proteins in all three species (human, chicken and duck). …”
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MAP kinase gene STK1 is required for hyphal, conidial, and appressorial development, toxin biosynthesis, pathogenicity, and hypertonic stress response in the plant pathogenic fungu... by Po LI, Xiao-dong GONG, Hui JIA, Yong-shan FAN, Yun-feng ZHANG, Zhi-yan CAO, Zhi-min HAO, Jian-min HAN, Shou-qin GU, Jin-gao DONG

“…In addition, gene knockout technology was employed to investigate the function of STK1. Gene knockout mutants (KOs) were found to have altered hyphae morphology and no conidiogenesis, though they did show similar radial growth rate compared to the wild-type strain (WT). …”
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Reproductive Potential and Population Growth of the Worm <i>Enchytraeus buchholzi</i> (Clitellata: Enchytraeidae) Under Laboratory Conditions as Well as Regression Models by Limin Zhao, Guilan Ma

“…In Experiment II, both an exponential and a logistic function were applied to construct regression equations. …”
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