Effect of Intramuscular Injection of Vitamin D on 25-Hydroxyvitamin D Levels, Glycaemic Control, and Liver Enzymes in Libyan Patients with Type 2 Diabetes Mellitus by Hafsa M. Alemam, Mouna M. ElJilani, Abdulla M. Bashein

“…In addition, it has a positive effect on improving liver enzyme function. Aim This study was performed to examine the effect of intramuscular injection of vitamin D on serum 25-hydroxyvitamin D [25(OH)D] levels, glycemic control, and liver enzymes in Libyan patients suffering from type 2 diabetes mellitus (T2DM) with vitamin D deficiency. …”
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Association between triglyceride-glucose-body mass index and adverse prognosis in elderly patients with severe heart failure and type 2 diabetes: a retrospective study based on the... by Jing Cheng, Qi Cheng, Yingting Wu, Jiashun Yin, Fei He

“…Compared to Q4, Q1 (lowest TyG-BMI) had significantly higher mortality at 90 days (58.70% vs. 48.45%; p = 0.008) and 365 days (80.54% vs. 73.91%; p < 0.001), with similar 60-day trends (58.79% vs. 39.34%; p = 0.059). …”
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Analysis of pelvic floor anatomy in pelvic floor dysfunction syndrome based on four-dimensional ultrasonography of the perineum dynamic examination by Mu Liang, Xu Jiaojiao, Chen Hao, Nan Shuliang, Liu Wei, Xue Yuhong, Liu Li

“…At rest, the two groups had no significant difference in the area of the levator ani hiatus structure and ARA (P>0.05). …”
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Evaluation of Efficacy and Safety of Empagliflozin in Bangladeshi Patients with Type 2 Diabetes Mellitus (EFFISAEM Study) by Mohammad Saifuddin, Ajit K. Paul, Sultana M. Shefin, Md. Jahangir Alam, Shahjada Selim, Sunjida Islam, Tanjina Hossain, Sadiqa Tuqan, Nusrat Sultana, Marufa Mustari, Ramen C. Basak, Kazi A. Aftab, Indrajit Prasad, Mohammad R. Uddin, Shoma Sharker, Md. Abu Jar Gaffar, Mohammad M. Rahman, Mohammad A. Hannan, Afsar Ahammed, ABM Kamrul-Hasan

“…Patients with T2DM who met the criteria had Empagliflozin added to their existing GLD treatment, with necessary modifications to their ongoing medication regimen. …”
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Detection of CRISPR‒Cas and type I R–M systems in Klebsiella pneumoniae of human and animal origins and their relationship to antibiotic resistance and virulence by Xue Li, Ling Wang, Jinghuan Lin, Yingjuan Gu, Zhihua Liu, Jing Hu

“…The results showed that host origin had no obvious influence on the distributions of the two systems (CRISPR‒Cas systems in 29.8% and 24.1%, type I R-M systems in 9.8% and 11.8% of human-origin and animal-origin strains, respectively) in K. pneumoniae. …”
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Genetic association analysis between LDL-c lowering drugs and portal hypertension using Mendelian randomization analysis by Qing-Ao Xiao, Xiao-Long Li, Lei Qin, Xiao-Lin Zhang

“…The IVs of target genes were subjected to MR analysis with coronary atherosclerosis (CAD) as a positive control, confirming that the IVs can effectively substitute for the biological function of the target gene, thereby further enhancing the reliability of the results. …”
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Observation on the clinical effectiveness of intermuscular suture combined with fullthickness advancement flap in the treatment of suprasphincteric anal fistula: a series of 33 cas... by Yang Xiaoyuan, Chen Wenping, Lin Wanlin, Ma Qiaoling, Zhang Lei, Zhu Jiandong, Zhao Shen, Yang Limin, Ma Zhiteng, Huang Shaoling, Yuan Yuewen

“…The treatment outcomes (cure or treatment failure), disease-related information, anal function, and patient’s satisfaction with surgical treatment were recorded. …”
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Syndrome of hepatogenic photosensitization in cattle fed with bagasse: etio-pathogenetic relationships and features of the course – a case report by O. V. Chub, N. V. Vovkotrub, V. I. Koziy, A. Yu. Melnyk, O. V. Piddubnyak, A. V. Kharchenko, V. V. Hrytsai, O. V. Yeroshenko

“…At the same time, the cows had hepatomegaly, a violation of the functional state of the liver, which was characterized by a decrease in its protein-synthesizing function with the development of hypoproteinemia, an increase in the activity of aminotransferases in the blood serum - AST more than 110 U/l and ALT more than 35 U/l, a sharp positive reaction of the formalin test. …”
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Scaling Relationships Among the Floral Organs of <i>Rosa chinensis</i> var. <i>minima</i>: Implications for Reproductive Allocation and Floral Proportionalities by Zhe Wen, Karl J. Niklas, Yunfeng Yang, Wen Gu, Zhongqin Li, Peijian Shi

“…The two-parameter Weibull probability density function was also applied to characterize the distributions of floral organ mass, and revealed skewed tendencies in all six measured traits. …”
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Adherence to the planetary health diet is associated with slower cognitive decline: a prospective cohort analysis of Chinese older adults by Lulu Tang, Xiaoli Yu, Changcui Qiu, Yu Lu, Yunlan Wang, Fei Liu, Xiaoping Zhu

“…Dietary intake was assessed using 3-day 24 h dietary recalls combined with weighing methods and cognitive function was assessed using repeated measures of the Telephone Interview for Cognitive Status-modified (TICS-m). …”
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The evaluation of Thai herbal Leard-Ngam formula for relieving pain in primary dysmenorrhea: Randomized controlled trial by Sunisa Leemud, Kusuma Sriyakul, Chuntida Kamalashiran, Sucharat Tungsukruthai, Somboon Kietinun, Parunkul Tungsukruthai

“…In addition, blood chemistry, hematology, liver, and renal function were all within normal ranges. Moreover, there were six incidences of side effects in the MA group, but only one in the LG group. …”
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Risk factors for IgA nephropathy recurrence and impact on graft survival in a cohort of kidney transplanted patients by Angelodaniele Napoletano, Michele Provenzano, Federica Maritati, Valeria Corradetti, Vania Cuna, Elisa Gessaroli, Chiara Abenavoli, Simona Barbuto, Marcello Demetri, Matteo Ravaioli, Giorgia Comai, Gaetano La Manna

“…The aim of this study was to determine incidence, risk factors and impact on renal function and graft survival of IgAN recurrence after KT. …”
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Augmenting Parenting Programs With the Pause Mobile App: Mixed Methods Evaluation by Nathan Hodson, Peter Ivor Woods, Stephanie Donohoe, Juan Luque Solano, James Gardner, Manuel Giardino, Michael Sobolev, Domenico Giacco

“…Most of the parents (23/25, 92%) had used Pause. Other than the journal, used by 17 parents, the most popular tools were the relax tool and praise tool, each used by 10 parents. …”
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Long-term survival after multidisciplinary therapy for residual gallbladder cancer with peritoneal dissemination: a case report by Daisuke Kuga, Tomoki Ebata, Yukihiro Yokoyama, Tsuyoshi Igami, Gen Sugawara, Takashi Mizuno, Junpei Yamaguchi, Masato Nagino

“…Since the patient’s general condition and liver function reserve were satisfactory, we decided the initial unresectable scenario to perform surgical therapy. …”
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Hydroxychloroquine is associated with lower platelet activity and improved vascular health in systemic lupus erythematosus by Peter Izmirly, H Michael Belmont, Jill P Buyon, MacIntosh Grant Cornwell, Elliot S Luttrell-Williams, Michael Golpanian, Hanane El Bannoudi, Khrystyna Myndzar, Stuart Katz, Nathaniel R Smilowitz, Alexis Engel, Robert Clancy, Kelly Ruggles, Jeffrey S Berger

“…Gene expression of P-selectin (SELP) was inversely correlated with HCQ dose (r=−0.41, p=0.003), which was validated at the protein level. Subjects on HCQ had improved vascular function correlating with HCQ dose as measured by lower PBR (r=−0.52, p=0.007), higher RBCF (r=0.55, p=0.004) and greater brachial artery reactivity (r=0.43, p=0.056).Conclusion HCQ use was associated with decreased platelet activation and activation-related transcripts and improved vascular health in SLE.…”
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New information on the Hind limb feathering, soft tissues and skeleton of Microraptor (Theropoda: Dromaeosauridae) by Matthieu Chotard, Xiaoli Wang, Xiaoting Zheng, Thomas G. Kaye, Maxime Grosmougin, Luke Barlow, Martin Kundrát, T. Alexander Dececchi, Michael B. Habib, Juned Zariwala, Scott Hartman, Xing Xu, Michael Pittman

“…Its striking difference with most paravians contributes to the multiple theories on the function of its conspicuous hind limbs. Recent studies tried to uncover its evolutionary significance, but its anatomy has only been described from a small number of samples. …”
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Results of rehabilitation of myasthenia gravis patients with subclinical respiratory disturbances by Yu. N. Rushkevich, O. V. Galievskaya, M. P. Mozheyko, S. A. Likhachev

“…The external respiration function was studied before and after the rehabilitation course. …”
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Extração de fósforo em solos cultivados com cana-de-açúcar e suas relações com a capacidade tampão Extraction of phosphorus in soils cultivated with sugarcane and relationship with... by Djalma E. Simões Neto, Alexandre C. de Oliveira, Fernando J. Freire, Maria B. G. dos S. Freire, Clístenes W. A. do Nascimento, Alexandre T. da Rocha

“…The treatments consisted of seven doses of P, determined in function of the P maximum capacity of adsorption (PMCA). …”
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Molecular simulations reveal intricate coupling between agonist-bound β-adrenergic receptors and G protein by Yanxiao Han, John R.D. Dawson, Kevin R. DeMarco, Kyle C. Rouen, Khoa Ngo, Slava Bekker, Vladimir Yarov-Yarovoy, Colleen E. Clancy, Yang K. Xiang, Surl-Hee Ahn, Igor Vorobyov

“…Using advanced computer modeling and simulation, we identified atomistic-level structural, dynamic, and energetic mechanisms of norepinephrine (NE) and stimulatory G protein (Gs) interactions with β-adrenergic receptors (βARs), crucial GPCRs for heart function regulation and major drug targets. Our analysis revealed distinct binding behaviors of NE within β1AR and β2AR despite identical orthosteric binding pockets. β2AR had an additional binding site, explaining variations in NE binding affinities. …”
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Silicon-Mediated Modulation of Olive Leaf Phytochemistry: Genotype-Specific and Stress-Dependent Responses by Marin Cukrov, Velemir Ninkovic, Luna Maslov Bandić, Šime Marcelić, Igor Palčić, Mario Franić, Paula Žurga, Valerija Majetić Germek, Igor Lukić, Darija Lemić, Igor Pasković

“…The extent of silicon’s prophylactic function may therefore be dependent on a genotype’s metabolic foundation and overall sensitivity, and as such it seems inseparable from stress and its intensity.…”
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