The Activity of Human NK Cells Towards 3D Heterotypic Cellular Tumor Model of Breast Cancer by Anastasia Leonteva, Maria Abdurakhmanova, Maria Bogachek, Tatyana Belovezhets, Anna Yurina, Olga Troitskaya, Sergey Kulemzin, Vladimir Richter, Elena Kuligina, Anna Nushtaeva

“…We observed that IL-15 and IL-2 enhanced NK cell activity within spheroids, whereas TGFβ had varying effects on proliferation depending on the cell type. …”
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Water-fertilizer regulation improves yield, quality, and water-fertilizer use efficiency of greenhouse lettuce by altering the bacterial community in nutrient solutions by Qingqing Zhao, Junjie Feng, Shulong Guo, Shenjiao Yang, Rui Jing, Xiaobin Zhang, Xinguo Zhou, Dongwei Li

“…Redundancy analysis identified that nutrient indicators served a pivotal function in shaping bacterial community structures within the nutrient solution. …”
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Effects of Chicken Protein Hydrolysate as a Protein Source to Partially Replace Chicken Meal on Gut Health, Gut Microbial Structure, and Metabolite Composition in Cats by Tong Yu, Fabian Humbert, Dan Li, Arnaud Savarin, Mingrui Zhang, Yingyue Cui, Haotian Wang, Tianyu Dong, Yi Wu

“…Protein hydrolysates positively affect intestinal function in both humans and animals, but their impact on gut health and the gut microbial profile in cats has not been thoroughly investigated. …”
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Prevalence of subclinical hypothyroidism in polycystic ovary syndrome and its impact on insulin resistance: a systematic review and meta-analysis by Arman Shekarian, Sadegh Mazaheri-Tehrani, Saba Shekarian, Melika Pourbazargan, Mahsa Setudeh, Amir Parsa Abhari, Mohammad Fakhrolmobasheri, Maryam Heidarpour

“…PCOS patients with SCH had significantly higher HOMA-IR (WMD = 0.78, 95% CI: 0.34; 1.22) and fasting insulin (WMD = 2.38, 95% CI: 0.34; 4.42) levels than those without SCH. …”
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Comparison of clinical nasal endoscopy, optical biopsy, and artificial intelligence in early diagnosis and treatment planning in laryngeal cancer: a prospective observational study by Ruifang Hu, Xianping Liu, Yong Zhang, Clement Arthur, Dongguang Qin

“…Prompt diagnosis is crucial to improving survival and function. Direct laryngoscopy and imaging modalities are conventional diagnostic methods. …”
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Triglyceride glucose index predicts long-term mortality and major adverse cardiovascular events in patients with type 2 diabetes by Matilde Sbriscia, Dalila Colombaretti, Angelica Giuliani, Silvia Di Valerio, Lucia Scisciola, Iryna Rusanova, Anna Rita Bonfigli, Fabiola Olivieri, Jacopo Sabbatinelli

“…Results Patients with T2D exhibited higher TyG Index values compared to CTR, with significant correlations between the TyG Index and markers of obesity, glucose metabolism, inflammation, and liver function. Patients with preexisting diabetic kidney disease (DKD) or atherosclerotic vascular disease had higher baseline values of TyG index. …”
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Enhancing broiler growth and carcass quality: impact of diets enriched with Moringa oleifera leaf powder conjugated with zinc nanoparticles by Mohammed M. El-Abbasy, Ahmed K. Aldhalmi, Elwy A. Ashour, Samar S. Bassiony, Mahmoud Kamal, Abdulmohsen H. Alqhtani, Diaa E. Abou-Kassem, Ahmed A. Elolimy, Mohamed E. Abd El-Hack, Ayman A. Swelum

“…Malondialdehyde (MDA) levels were reduced, indicating improved antioxidant capacity and immune function in the ZnNPs-MLPE-treated groups. In conclusion, supplementation with ZnNPs-MLPE at 2.0 and 3.0 cm³/L positively impacted broiler growth efficiency, antioxidant capacity, and immunological functionality. …”
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Eye-hand preference dissociation in obsessive-compulsive disorder and dyslexia Dissociação da preferência ocular e manual em pacientes com transtorno obsessivo-compulsivo e dislexi... by Marilena Occhini Siviero, Eliana Oliveira Rysovas, Yara Juliano, José Alberto Del Porto, Paulo Henrique Ferreira Bertolucci

“…Dyslexia may be a development disturbance in which there are alterations in visual-spatial and visual-motor processing, while obsessive-compulsive disorder (OCD) is a psychiatric disease in which there are alterations in memory, executive function, and visual-spatial processing. Our hypothesis is that these disturbances may be, at least partially, the result of a crossed eye and hand preference. …”
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Identification and Validation of circDOCK1/miR-138-5p/GRB7 Axis for Promoting Breast Cancer Progression by Zhang Y, Yang M, Wang Y, Zhao J, Lee PY, Ma Y, Qu S

“…The expression level of circDOCK1 in breast cancer specimens was measured using qRT-PCR. Functional rescue experiments were conducted to explore the role of circDOCK1/miR-138-5p/GRB7 axis in breast cancer cells. …”
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Effect of Cananga odorata modulates cholinergic, purinergic enzymes, and elevates antioxidant markers in diabetes-induced cognitive disorder rat brain by Jamiyu A. Saliu, Olajide R. Ojo, Idowu S. Oyeleye, Ganiyu Oboh

“…ROS and TBARS were considerably higher in the DM group but were successfully decreased by COLE treatment. The DM group had reduced levels of GSH and SOD activity, which was recovered with COLE. …”
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Evaluation of the Effects of Switching COPD Patients From LAMA/LABA Therapy to ICS/LAMA/LABA Therapy Using the Impulse Oscillation System (IOS) Capable of Separating Inspiratory an... by Yosuke Tanaka, Ken Okamura, Shota Kaburaki, Toru Tanaka, Akiko Yoshikawa, Ayumi Shimizu, Akihiko Miyanaga, Namiko Taniuchi, Koichiro Kamio, Kazuo Kasahara, Masahiro Seike, Mitsunori Hino

“…Results Among 52 patients (mean baseline %FEV1/predicted: 56.9% ± 22.1%), all had one to two moderate exacerbations in the past year despite LAMA/LABA therapy. …”
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Brain Activation Pattern Caused by Soft Rehabilitation Glove and Virtual Reality Scenes: A Pilot fNIRS Study by Pengju Liu, Xinyi Yang, Fenglin Han, Guangshuai Peng, Qiao Li, Liping Huang, Lizhen Wang, Yubo Fan

“…Clinical studies have proved significant improvements in hand motor function in stroke patients when assisted by robotic devices. …”
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Cerebral microbleeds: prevalence and relationship to clinical features in cognitive impairment with lewy body disease by Zhihong Ren, Jinghuan Gan, Zhichao Chen, Zhihong Shi, Shuai Liu, Hao Lu, Guili Zhang, Yong Ji

“…Conclusion Patients with DLB had a higher proportion of CMBs than PDD, MCI-LB and PD-MCI. …”
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Hsa_circ_0005571 promotes the proliferation and invasion of colorectal cancer cells by Haipeng Ge, Jiaxuan Zhang, Ran Tao, Li Ding, Song Jiang, Jiale Shen, Longjun Bian, Jun Qin

“…Bioinformatic predictions and experimental evidence indicated that hsa_circ_0005571 may function as a sponge for miR-520f-3p, which was found to be downregulated in CRC cells. …”
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Rational design of some 1,3,4 trisubstituted pyrazole-thiazole derivatives to serve as MtInhA inhibitors using QSAR, ADMET, molecular docking, MM-GBSA, and molecular dynamics simul... by Neha M. Mhetre, Aniket L. Bhatambrekar, D. Priya, Venkatesan Saravanan, Muthukumaradoss Kathiravan, Krishna S. Shevate, Kalirajan Rajagopal, Kalyani D. Asgaonkar, Trupti S. Chitre

“…Among the designed compounds, AP2 had the strongest binding affinity towards the MtInhA enzyme. …”
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Evaluation of serum Cystatin C as a predictor of eGFR in type 2 diabetic patients with nephropathy by Aqsa Fatima, Pooran Mal, Zoheb Rafique Memon, Mukesh Kumar, Haseeb Jameel Memon, Misbah Fatima

“…The strong negative relationship between Cystatin C and eGFR supports its potential role as a valuable marker for assessing renal function in diabetic patients. …”
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Frequency, intensity and duration of physical activity is associated with frailty in older adults with cardiac aging by Laureen Y. T. Wang, Wee Shiong Lim, Ru-San Tan, Louis L. Y. Teo, Shu Yun Tan, Chun How Ooi, Alvin Cong Wei Ong, Jean-Paul Kovalik, Jorming Goh, Fei Gao, Angela S. Koh

“…More than half of community older adults had physical frailty with or without cardiac aging. …”
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Numerical solution of KdV-mKdV equation based on PINN and its improved method(基于PINN及其改进算法求解KdV-mKdV方程) by 栗雪娟(LI Xuejuan), 刘瑜欣(LIU Yuxin)

“…Physics-informed neural network (PINN) had been proved to be an effective tool for solving partial differential equations and systems of equations. …”
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The autoimmune disease risk variant NCF1-His90 is associated with a reduced risk of tuberculosis in women by Xinjun Hu, Shasha Li, Renliang Huang, Ziwei Fu, Chenyu Ma, Zheng Cheng, Hongjun Hu, Qiaomiao Zhou, Frank Petersen, Xinhua Yu, Xinhua Yu, Junfeng Zheng

“…IntroductionThe neutrophil cytosolic factor 1 (NCF1) rs201802880 polymorphism is a missense mutation resulting in an amino acid substitution from arginine to histidine at position 90, which impairs the function of NADPH oxidase. This casual variant confers an increased risk for multiple autoimmune disorders, including primary Sjögren’s syndrome and systemic lupus erythematosus. …”
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Ziziphus spina-christi alleviates paracetamol-induced hepatorenal toxicity in rats through in vivo and computational approaches by Ehsan Kh. M. Khedre, Amany M. M. Hegab, Amira A. El-Mahis, Amina A. S. Abdel Rahman, Sherien H. B. Elwakeel, Ali S. Abdelhameed, Vittorio Calabrese, Ursula M. Jacob, Eman S. G. Hassan

“…The study included biochemical analysis of liver and kidney function markers, oxidative stress indicators, histological and immunohistochemical examinations, and molecular docking studies. …”
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