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Mechanisms underlying CSD initiation implicated by genetic mouse models of migraine
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Effects of proton pump inhibitor (PPI) use on migraine – a critical review
Published 2025-01-01“…In the last few years, a potential link between PPI intake and the development of headaches—especially migraine–has come to increased attention. …”
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Rimegepant for the treatment of migraine
Published 2022-10-01“…Migraine is a common form of primary headache, affecting up to 1 in every 6 Americans. …”
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Migraine and restless legs syndrome – is there an association?
Published 2023-10-01“…Moreover, comorbidity of these disorders determines even more difficult condition of the patients. Migraine is a headache that can cause severe throbbing pain, usually on one side of the head, and it is often accompanied by nausea, vomiting, and extreme sensitivity to light and sound. …”
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Neural Plasticity in Common Forms of Chronic Headaches
Published 2015-01-01“…In this review, we provide a narrative overview of recent advances on the neuroimaging, electrophysiological and genetic aspects of neural plasticity associated with the most common forms of chronic headaches, including migraine, cluster headache, tension-type headache, and medication overuse headache.…”
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A Comprehensive Review of Zavegepant as Abortive Treatment for Migraine
Published 2022-06-01“…Migraine headache is a widespread and complex neurobiological disorder that is characterized by unilateral headaches that are often accompanied by photophobia and phonophobia. …”
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Current and Novel Therapies for Cluster Headache: A Narrative Review
Published 2024-11-01“…Abstract Cluster headache (CH) is an excruciating and debilitating primary headache disorder. …”
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Machine learning-driven identification of critical gene programs and key transcription factors in migraine
Published 2025-01-01“…Abstract Background Migraine is a complex neurological disorder characterized by recurrent episodes of severe headaches. …”
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Familial Hemiplegic Migraine with Severe Attacks: A New Report with ATP1A2 Mutation
Published 2016-01-01“…Results. 22-year-old woman was admitted due to migraine-type headache and sudden onset of right-sided weakness and aphasia; she had similar episodes in her childhood. …”
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The link between spreading depolarization and innate immunity in the central nervous system
Published 2025-02-01“…Inflammation extends beyond the central nervous system to peripheral structures, including the meninges and trigeminovascular system, which are critical for headache initiation. Genetic factors, particularly familial hemiplegic migraine (FHM), exacerbate neuroinflammatory responses to SD, leading to increased susceptibility and prolonged headache behaviors. …”
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Targeted Regulation Of Cgrp Gene Expression
Published 2001-01-01“…Clinical studies have shown that CGRP levels are elevated during the painful phase of migraine headache, then restored to baseline by antimigraine 5-HT1 drugs. …”
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Understanding the Spectrum of Mild Clinical Outcomes and Novel Findings in Arterial Tortuosity Syndrome Among Qatari Patients: Implications of SLC2A10 Mutation
Published 2025-01-01“…Furthermore, rare features previously documented in a limited number of patients, including leg length discrepancy, epilepsy, and migraine headaches, were also observed in our cohort. …”
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