Protease-activated receptor-2 (PAR2) mutation attenuates airway fibrosis in mice during the exacerbation of house dust mite‑induced allergic lung disease by multi‑walled carbon nan... by Logan J. Tisch, Ryan D. Bartone, Silvio Antoniak, James C. Bonner

“…Methods The PAR2-mutant mice used were previously generated by replacing a 1.8-kb region of the PAR2 coding sequence with a neomycin resistance gene, which did not entirely delete the gene. …”
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miR-23b-3p, miR-126-3p and GAS5 delivered by extracellular vesicles inhibit breast cancer xenografts in zebrafish by Iulia Andreea Pelisenco, Daniela Zizioli, Flora Guerra, Ilaria Grossi, Cecilia Bucci, Luca Mignani, Giulia Girolimetti, Riccardo Di Corato, Vito Giuseppe D’Agostino, Eleonora Marchina, Giuseppina De Petro, Alessandro Salvi

“…Here, by using breast cancer (BC) cells treated with the multi-kinase inhibitor sorafenib, we generated EVs enriched in specific non-coding RNAs (miR-23b-3p, miR-126-3p, and the long ncRNA GAS5) and investigated their potential impact on the aggressive properties of the BC in vitro and in vivo using zebrafish. …”
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Comparison of Zebrafish tmem88a mutant and morpholino knockdown phenotypes. by Alexander M J Eve, Elsie S Place, James C Smith

“…Several groups have used antisense morpholino oligonucleotides in an effort to characterise the role of tmem88a in zebrafish cardiovascular development, but they have not obtained consistent results. Here, we generate an 8 bp deletion in the coding region of the tmem88a locus using TALENs, and we have gone on to establish a viable homozygous tmem88aΔ8 mutant line. …”
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Exploring large language models for summarizing and interpreting an online brain tumor support forum by Christy Muasher-Kerwin, M Courtney Hughes, Michelle L Foster, Ibrahim Al Azher, Hamed Alhoori

“…Summaries produced by LLMs aligned closely with human-generated thematic analysis, with significant reductions in time and labor. …”
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Inhalation hazard of radioactive aerosols from dismantling in-core structural components in a pressurized heavy water reactor during decommissioning by Tanmay Sarkar, Chitra Subramanian, S Anand

“…We assess inhalation doses from radioactive aerosols generated during the cutting process using the ORIGEN2 code for material activation and the FLUKA code for external dose rate simulations. …”
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Assessing the Impact of Past Flood on Rice Production in Batticaloa District, Sri Lanka by Suthakaran Sundaralingam, Kenichi Matsui

“…Temporal-spatial maps were generated using Google Earth Engine JavaScript coding, Google Earth Pro, and OpenStreetMap. …”
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Multifactor Algorithm for Test Case Selection and Ordering by Atulya Gupta, Rajendra Prasad Mahapatra

“…Intra-validation for the result achieved from the reduction procedure is performed graphically. This study contrasts randomly generated sequences with procured re-ordered test sequence for over '10' benchmark codes for the proposed prioritization scheme. …”
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Vascular dysfunction in a mouse model of Rett syndrome and effects of curcumin treatment. by Anna Panighini, Emiliano Duranti, Ferruccio Santini, Margherita Maffei, Tommaso Pizzorusso, Niccola Funel, Stefano Taddei, Nunzia Bernardini, Chiara Ippolito, Agostino Virdis, Mario Costa

“…Mutations in the coding sequence of the X-linked gene MeCP2 (Methyl CpG-binding protein) are present in around 80% of patients with Rett Syndrome, a common cause of intellectual disability in female and to date without any effective pharmacological treatment. …”
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Designing the alignment model of petrochemical projects with the country's industrial strategies in the Ministry of Petroleum by Abdolrasoul Shojaeian, ghanbar abbaspour esfadan, Changiz Valmohammadi, Aboutorab Alirezaei

“…Data analysis and model design were done through coding. The findings of the research showed that the alignment of the refinery projects with the country's industrial strategies in the Ministry of Oil, the enablers of the alignment include the maturity of communication and managerial factors and the exercise of authority, strategic technology planning and organizational architecture aligned with technology, partnership factors, human resources (innovation, entrepreneurship, expertise, knowledge), and the distinctive competence factors that lead to the realization of optimization results and reduction of capital and current costs and synergy in both sides of petro-refining and industry. …”
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An Improved Orthogonal Frequency Division Multiplexing System-Based Image Steganography Technique by Ali Y. Jaber, Ammar Al-Khafaji, Ahmed Mahfodh Mkhelf

“…In the case of an additive white Gaussian noise channel, the computer simulation results demonstrated that the CFO was reduced by approximately 5.2 dB and 7.15 dB in QPSK and 64QAM, respectively, compared to the original variance method. In this context, a coding method was proposed to hide secret data in an image before the OFDM generation process based on the Least Significant Bit (LSB1 &LSB2) technology. …”
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Spontaneous mutation reveals influence of exopolysaccharide on Lactobacillus johnsonii surface characteristics. by Nikki Horn, Udo Wegmann, Enes Dertli, Francis Mulholland, Samuel R A Collins, Keith W Waldron, Roy J Bongaerts, Melinda J Mayer, Arjan Narbad

“…During growth of the bacterium a rare but consistent emergence of an altered phenotype was noted, generating smooth colonies in contrast to the wild type rough form. …”
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“You get the money after waiting for long and you get less than you anticipated”: Experiences of persons with disabilities in accessing the district special grant in Uganda by Patrick Ojok, Joseph Mukasa

“… In 2010, Uganda scrapped an ambitious tax incentive provision in the Persons with Disabilities Act, 2006 that had allowed employers to claim up to 15% tax reduction in annual income provided that they hired at least 10 persons with disabilities at any job level. …”
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Malware Detection using Deep Neural Networks on Imbalanced Data by Mohammed Abdulkreem Mohammed, Drai Ahmed Smait, Mustafa Al-Tahai, Israa S. Kamil, Kadhum Al-Majdi, Shahad K. Khaleel

“…By employing the wrapper approach for dimensionality reduction, a feature subset was generated. In this paper, we propose an approach for handling the malware detection task in imbalanced data situations. …”
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Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice by Ali Yousefian-Jazi, Suhyun Kim, Jiyeon Chu, Seung-Hye Choi, Phuong Thi Thanh Nguyen, Uiyeol Park, Min-gyeong Kim, Hongik Hwang, Kyungeun Lee, Yeyun Kim, Seung Jae Hyeon, Hyewhon Rhim, Hannah L. Ryu, Grewo Lim, Thor D. Stein, Kayeong Lim, Hoon Ryu, Junghee Lee

“…However, the mechanism behind genetic mutations in the non-coding region of genes that affect epigenetic modifications remains unclear. …”
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Harder, Better, Faster, Stronger? Residents Seeing More Patients Per Hour See Lower Complexity by Corlin M. Jewell, Guangyu (Anthony) Bai, Dann J. Hekman, Adam M. Nicholson, Michael R. Lasarev, Roxana Alexandridis, Benjamin H. Schnapp

“…We compared the number of PPH seen during the third (final) year to patient acuity (Emergency Severity Index), complexity (Current Procedural Terminology codes [CPT]), propensity for admissions, and generated relative value units (RVU). …”
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Biochemical and phylogenetic characterization of the wastewater tolerant Chlamydomonas biconvexa Embrapa|LBA40 strain cultivated in palm oil mill effluent. by Patrícia Verdugo Pascoal, Dágon Manoel Ribeiro, Carolina Ribeiro Cereijo, Hugo Santana, Rodrigo Carvalho Nascimento, Andrei Stecca Steindorf, Lorena C G Calsing, Eduardo Fernandes Formighieri, Bruno S A F Brasil

“…Carbohydrates comprised the major fraction of algal biomass (31.96%), while the lipidic fraction reached up to 11.3% of dry mass. Reductions of 99% in ammonium and nitrite, as well as 98% reduction in phosphate present in POME were detected after 5 days of algal cultivation. …”
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Plastome and transcriptome analysis reveals a degenerated photosynthesis-related pathway in the mycoheterotrophic vanilloid orchid Cyrtosia lindleyana by Shiou Yih Lee, Peishan Zou, Zhihui Chen, Kenji Suetsugu, Wenbo Liao

“…Results The plastome, despite its reduction to 89,414 base pairs, maintained its quadripartite structure. …”
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Influence of Information Technology on the Performance of Financial Institutions in Ntungamo: A Case Study of Centenary Bank Ntungamo Branch. by Murungi, Doreen

“…The study applied primary data using questionnaires and secondary data collected from the respective institution’s financial statements and summaries at the Centenary Bank Ntungamo branch. Editing, coding, classifying, and tabulation are the processing steps that were used to process data for better and more efficient analysis. …”
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Significance of chemical reaction and velocity slip on Magnetized Sutterby Nanofluid over Stretchable Sheet by K Srihari, B. Shankar Goud, T Lokesh Babu

“…Based on similarity variables, we transformed the generated governing equations into ordinary differential equations. …”
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Mitigating host microRNA interference to enhance mRNA vaccine efficacy in public health interventions by Tielong Xu, Ziqi Lin, Yicheng Yu, Muhammad Irfan, Munir Ahmed, Maya Septriana, Twinky Zebrina Cysta Sumantri, Anindini Winda Amalia, Bin Zheng

“…Furthermore, the commentary suggests two actionable strategies for evading miR interference: (1) Synonymous codon optimization at seed-match regions, achieving binding energy reduction while preserving antigenicity through degeneracy of genetic coding; (2) Targeted co-delivery of miR inhibitors. …”
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