Genetic determinants of circulating sphingolipid concentrations in European populations. by Andrew A Hicks, Peter P Pramstaller, Asa Johansson, Veronique Vitart, Igor Rudan, Peter Ugocsai, Yurii Aulchenko, Christopher S Franklin, Gerhard Liebisch, Jeanette Erdmann, Inger Jonasson, Irina V Zorkoltseva, Cristian Pattaro, Caroline Hayward, Aaron Isaacs, Christian Hengstenberg, Susan Campbell, Carsten Gnewuch, A Cecilej W Janssens, Anatoly V Kirichenko, Inke R König, Fabio Marroni, Ozren Polasek, Ayse Demirkan, Ivana Kolcic, Christine Schwienbacher, Wilmar Igl, Zrinka Biloglav, Jacqueline C M Witteman, Irene Pichler, Ghazal Zaboli, Tatiana I Axenovich, Annette Peters, Stefan Schreiber, H-Erich Wichmann, Heribert Schunkert, Nick Hastie, Ben A Oostra, Sarah H Wild, Thomas Meitinger, Ulf Gyllensten, Cornelia M van Duijn, James F Wilson, Alan Wright, Gerd Schmitz, Harry Campbell

“…Therefore, sphingolipids represent novel and important intermediate phenotypes for genetic analysis, yet little is known about the major genetic variants that influence their circulating levels in the general population. …”
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A Universal Framework for Near-Real-Time Detection of Vegetation Anomalies from Landsat Data by Yixuan Xie, Zhiqiang Xiao, Juan Li, Jinling Song, Hua Yang, Kexin Lv

“…Vegetation anomalies are frequently occurring and may greatly affect ecological functions. Many near-real-time (NRT) detection methods have been developed to detect these anomalies in a timely manner whenever a new satellite observation is available. …”
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Reactive oxygen species responsive double-locked liposome collaborative photodynamic therapy for reducing electrical conduction recurrence after radiofrequency catheter ablation by Ying Zhuge, Gonghao Li, Mingyue Sun, Jiajia Zhang, Jiafeng Zou, Feng Gao, Fang Wang

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What factors are associated with informal carers’ psychological morbidity during end-of-life home care? A systematic review and thematic synthesis of observational quantitative stu... by Tracey Shield, Kerin Bayliss, Alexander Hodkinson, Maria Panagioti, Alison Wearden, Jackie Flynn, Christine Rowland, Penny Bee, Morag Farquhar, Danielle Harris, Gunn Grande

“…Newcastle–Ottawa Quality Assessment Scale was used. Thematic analysis with box score presentation, and meta-analysis were done where data permitted. …”
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Knockdown of p53 Enhances LncRNA A2M‐AS1 Inhibition of Pancreatic Cancer Progression via Regulating MAPK Pathway by Yu Cen, Yihui Luo, Yi Nan, Wenxi Kuang, Xianglian Zhang, Jiexia Lu, Chunxiao Xie, Mingzhi Xie, Enran Chen, Haixing Jiang, Shanyu Qin

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FMT reduces systemic inflammatory response in severe acute pancreatitis by increasing the abundance of intestinal Bifidobacteria and fecal bacteria by Yanning Mao, Yandong Huang, Weiwei Zhang, Huiping Liang, Fengming Liu, Qi Luo, Chunqin Xu, Yi Qin, Jiawen Liu, Shaobo Tang, Huaying Liu, Xiaolong Ge

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MECHANISM FOR DESIGNING COMPETENCE-ORIENTED TASKS IN VARIOUS ACADEMIC SUBJECTS AND REQUIREMENTS FOR ITS IMPLEMENTATION IN HIGHER EDUCATIONAL ESTABLISHMENTS by Natalya M. Zhukova, Petr F. Kubrushko, Marina V. Shingareva

“…The authors have systemized and extended general theoretical didactical views on the need for competence-oriented tasks as the educational ones (as a component of the teaching content and technology) and the criterion ones (as a method and means of monitoring the process and the result of developing students’ professional competence in the process of studying of different subjects); have specified the structure of the competence-oriented tasks (the structure elements: a condition, a requirement, and a construct) and determined the functions of the competence-oriented tasks in the modern university study process (gnostic, subject-and-activity, educational, axiological, creative, managing, motivation and incentive, control and assessment). …”
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Evolution of the concept of corporate social responsibility and ways of its development in modern Russia by A. N. Kurayev, I. G. Morozova, A. A. Grunina, N. M. Suray, M. V. Shatokhin

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One-year cognitive follow-up in patients hospitalized for COVID-19 in a cohort from Mexico by Rodríguez-Agudelo Yaneth, Paz-Rodríguez Francisco, Chávez-Oliveros Mireya, Lozano-Tovar Susana, Rodríguez-Rodríguez Mónica, Soto-Moreno Francisco-Javier, García-Santos Anwar, López-González Diana, González-Navarro Mauricio, Fuentes-Dominguez Mauro Fernando, Carrillo-Mezo Roger, Marrufo-Meléndez Oscar, Gutiérrez-Romero Alonso, Del Río Quiñones Manuel, Arauz-Góngora Antonio, Avila-Rios Santiago

“…This situation has consequences for the general and emotional functionality of patients. The aim of this work was to explore the prevalence of both global and specific impairments in various cognitive domains in a group of SARS-CoV-2 infection survivors with subjective memory-related complaints from the COVID-19 clinic of the National Institute of Respiratory Diseases. …”
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Biotesting of titanium tetrapolyethylene glycolate in 10 molar excess on granulosa cell culture of porcine follicles by A. O. Prituzhalova, T. I. Kuzmina, T. G. Khonina, U. S. Nikulina

“…After 22 and 44 hours, the GC were analyzed by flow cytometry. A comprehensive analysis of viability indicators (mitochondrial activity, apoptosis), as well as the generation of reactive oxygen species (ROS) in the GC after exposure to TTPEG*10PEG, revealed that the addition of 0.1 % TTPEG*10PEG to the culture medium after 22 and 44 hours causes disturbances in the functional activity of the GC, accompanied by a decrease of mitochondrial membrane potential compared to control (by 8 and 9 %, respectively, p<0.05) and cell death (the proportion of cells in apoptosis was 45 and 41 %, respectively, p<0.001). …”
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Early cardiac events after haploidentical hematopoietic cell transplantation with post-transplant cyclophosphamide. subanalysis exploring cardiac toxicity conducted on behalf of GE... by Filipe R. Pinto, Enric Cascos, Estefanía Pérez-López, Mónica Baile-González, Carlos Martín Rodríguez, María Jesús Pascual Cascón, Marta Luque, Albert Esquirol, Carmen Martín Calvo, Felipe Peña-Muñóz, Inmaculada Heras Fernando, Itziar Oiartzabal Ormtegi, Adolfo Jesús Sáez Marín, Sara Fernández-Luis, Juan José Domínguez-García, Sara Villar Fernández, José Luis López Lorenzo, Miguel Fernández de Sanmamed Girón, Leslie González Pinedo, Lucía García, Ana Pilar González-Rodriguez, Tamara Torrado, Silvia Filaferro, Pascual Basalobre, Alberto López-García, Guillermo Ortí, Guillermo Ortí, Manuel Jurado Chacón, Manuel Jurado Chacón, María Queralt Salas, María Queralt Salas

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SNHG12 downregulation induces follicular dysplasia by modulating the glycolysis of granulosa cell in polycystic ovary syndrome by Sisi Yan, Bing Qu, Yu Chen, Qiuji Wu, Jinli Ding, Hui Qiu

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Assessing the Antioxidant, Hepatoprotective, and Iron-Chelating Potential of <i>Perilla frutescens</i> Seed by Sirichatnach Pakdeepromma, Komsak Pintha, Payungsak Tantipaiboonwong, Chonthida Thephinlap, Maitree Suttajit, Sawaruj Kaowinn, Napapan Kangwan, Wanwisa Suwannaloet, Kanjana Pangjit

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Long-Term Quality of Life Among Intensive Care Units Survivors by Aljohani HY, Albarak NA, Alanazi TA, Alabdulsalam MA, Alzahrani RA, Algarni SS, Alotaibi TF, Alqahtani MM, Alqahtani MK, Ismaeil TT, Olayan LH

“…Additionally, being discharged for ≥ seven months improved general health (p=0.05). ICU survivors displayed notably lower scores in physical functioning (65 [IQR 55] vs 80 [IQR 45], p=0.00), limitations due to physical health (25 [IQR 100] vs 100 [IQR 75], p=0.00), limitations due to emotional problems (33.33 [IQR 100] vs 66.67 [IQR 100], p=0.00), less social functioning (62.5 [IQR 50] vs 75 [IQR 38], p=7.00), more pain 67.5 [IQR 45] vs 80 [IQR 33] (p=0.00), and general health (55 [IQR 25] vs 65 [IQR 23], p=0.00).Conclusion: ICU survivors experience significant HRQoL impairments exacerbated by prolonged ICU stays, highlighting the need for early and comprehensive rehabilitation services. …”
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Non-invasive biopsy diagnosis of diabetic kidney disease via deep learning applied to retinal images: a population-based study by Ziyao Meng, MEng, Zhouyu Guan, MD, Shujie Yu, MBBS, Yilan Wu, BSc, Yaoning Zhao, BSc, Jie Shen, PhD, Cynthia Ciwei Lim, MMed, Tingli Chen, MD, Dawei Yang, PhD, An Ran Ran, PhD, Feng He, MSc, Haslina Hamzah, BSc, Sarkaaj Singh, MSc, Anis Syazwani Abd Raof, MSc, Jian Wen Samuel Lee-Boey, MBBS, ProfMBBS Soo-Kun Lim, MBBS, ProfMD Xufang Sun, MBBS, Shuwang Ge, MD, ProfMD Gang Xu, MD, Prof Hua Su, MD, Yang Cheng, MD, Feng Lu, PhD, ProfPhD Xiaofei Liao, PhD, ProfPhD Hai Jin, PhD, Chenxin Deng, MMed, Lei Ruan, MD, ProfMD Cuntai Zhang, MD, Chan Wu, MD, ProfMD Rongping Dai, MD, Yixiao Jin, MSc, Wenxiao Wang, PhD, Tingyao Li, BSc, Ruhan Liu, PhD, Jiajia Li, PhD, Jia Shu, BEng, Yuwei Lu, MBBS, Xiangning Wang, MD, Qiang Wu, MD, Yiming Qin, BEng, Jin Tang, MD, Xiaohua Sheng, MD, Qiong Jiao, MD, ProfPhD Xiaokang Yang, MD, ProfPhD Minyi Guo, MD, Gareth J McKay, PhD, ProfPhD Ruth E Hogg, PhD, Gerald Liew, MBBS, Evelyn Yi Lyn Chee, PhD, ProfPhD Wynne Hsu, PhD, ProfPhD Mong Li Lee, PhD, Simon Szeto, MBChB, ProfMD Andrea O Y Luk, MBChB, ProfMD Juliana C N Chan, MBChB, Carol Y Cheung, PhD, Gavin Siew Wei Tan, FRCSEd, Yih-Chung Tham, PhD, ProfMD PhD Ching-Yu Cheng, PhD, Charumathi Sabanayagam, MD PhD, ProfPhD Lee-Ling Lim, MD PhD, ProfMD PhD Weiping Jia, MD PhD, ProfMD PhD Huating Li, MD PhD, Bin Sheng, Prof, Tien Yin Wong, Prof

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In vitro fermentation of whole matrix, digested products and β-glucan enriched extract of Pleurotus eryngii mushrooms distinctively impact the fecal microbiota of healthy older adu... by Evangelia N. Kerezoudi, Marigoula Vlassopoulou, Evdokia K. Mitsou, Georgia Saxami, Georgios Koutrotsios, Ioanna Taflampa, Konstantinos C. Mountzouris, Ignacio Rangel, Robert J. Brummer, Georgios I. Zervakis, Vasiliki Pletsa, Panagiotis Georgiadis, Adamantini Kyriacou

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The influence of the interaction of right ventricle and pulmonary artery system on the development of adverse outcomes in acute decompensation of chronic heart failure by Madina R. Islamova, Ayten F. Safarova, Zhanna D. Kobalava

“…The incidence of RV-PA uncoupling in the general population of patients with ADCHF was 67.2% (n=129). …”
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Potential confounding mutations in Keio knockout strains: implications for research accuracy by Oishi Sen, Xianghui Liu, Staffan Kjelleberg, Scott A. Rice, Thomas Seviour

“…A small number of SNPs and INDELs were predicted in the coding and intergenic regions of the knock-out mutants in comparison to the parental strain through sequencing and bioinformatic analysis. Mutations in the coding regions of genes (different from the actual gene knocked out in the mutants) led to different types of mutations in the affected genes, ranging from nonsense mutations to frameshift mutations, which could affect the functionality of the resulting gene products. …”
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Study results of rheological and baking parameters of dough from wholemeal bioactivated grain of hulless oats mixed with wheat flour by E. N. Shabolkina, S. N. Shevchenko, N. V. Anisimkina

“…In order to improve the biological value of bakery products and consumer properties of new products, there are used the technological additives and functional ingredients, which include bioactivated hulless oats. …”
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Promising pea varieties for use in the cereal industry in the south of Western Siberia by I. V. Pakhotina, L. V. Omeliyanyuk, E. Yu. Ignatieva, A. A. Asanov, L. T. Soldatova

“…The purpose of the study was to conduct a comparative analysis of varieties and breeding lines of domestic and foreign breeding and identify those suitable for processing into cereals. …”
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