Plasminogen activator inhibitor 1 is a novel predictor in human serum/follicular fluid for diminished ovarian reserve by Xinshu Li, Xue Chen, Hua Guo

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AI and Primary Care: Scoping Review by Gellert Katonai, Nora Arvai, Bertalan Mesko

“…However, existing research often overlooks how AI tools function within the complex realities of primary care and how clinicians and patients experience them. …”
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Targeted demethylation of the EphA7 promoter inhibits tumorigenesis via the SP1/DNMT1 and PI3K/AKT axes and improves the response to multiple therapies in cervical cancer by Wenfan Zhang, Jing Zhao, Xueting Fan, Shuang Chen, Rong Wang

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Diagnosis and treatment of 23 cases of acute nephritis syndrome with lung injury by 张媛媛, 袁发焕

“…After 3 years of follow-up, 5 patients died, 9 patients entered maintenance hemodialysis treatment, and 6 patients experienced chronic renal insufficiency without dialysis, and 3 patients had normal renal function.Conclusions Acute nephritis syndrome with lung injury has multiple etiology, a rapid clinical progress and poor prognosis. …”
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Data from multi-national aging cohorts show dysregulated metabolic pathways in people with physio-cognitive decline by Yi-Long Huang, Wei-Ju Chang, Chao-Hsiung Lin, Shu Zhang, Yukiko Nishita, Rei Otsuka, Wei-Ju Lee, Chih-Kuang Liang, Ming-Yueh Chou, Li-Ning Peng, Hidenori Arai, Luigi Ferrucci, Liang-Kung Chen

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Akkermansia muciniphila ameliorates doxorubicin-induced cardiotoxicity by regulating PPARα-dependent mitochondrial biogenesis by Hui Lin, Xian Shao, Haodi Gu, Xinrou Yu, Lingyan He, Jiedong Zhou, Zuoquan Zhong, Shitian Guo, Dan Li, Fei Chen, Yongfei Song, Lili Xu, Ping Wang, Liping Meng, Jufang Chi, Jiangfang Lian

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Incidence and Predictors of Postoperative Delirium in Patients Undergoing Elective Hip and Knee Arthroplasty: A Prospective Observational Study by James Paul, Amir Hamid, Heung Kan Ma, Thomas Kim, Lehana Thabane, Thuva Vanniyasingam

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Omega-3 Fatty Acids and Neuroinflammation in Depression: Targeting Damage-Associated Molecular Patterns and Neural Biomarkers by Ikbal Andrian Malau, Jane Pei-Chen Chang, Yi-Wen Lin, Cheng-Chen Chang, Wei-Che Chiu, Kuan-Pin Su

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The current role of pentafecta outcomes in open and laparoscopic partial nephrectomy for localized renal tumors by Aly M. Abdel-Karim, Omar A. Bakheet, Gamal Alsagheer, Mostafa AbdelRazek

“…Primary outcomes focused on predictors of pentafecta achievement; secondary outcomes included blood loss, operative time, hospital stay, pain scores, complications, recurrence, and renal function. Statistical analysis was performed using SPSS v26.0, with significance set at p < 0.05. …”
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Improving Nutritional Status in Chronic Heart Failure Patients: Effectiveness of a Transtheoretical Model-Based Stepwise Nutritional Management Program by Yuan D, Xue Y, Zhou Y

“…The Minnesota Living with Heart Failure Questionnaire (MLHFQ) scores in the observation group were significantly lower than in the control group (P &lt; 0.05).Conclusion: The nutritional status of CHF patients is generally poor, and the transtheoretical model-based stepwise nutritional management program can effectively improve their nutritional status, enhance cardiac function, improve quality of life, and alleviate psychological burden. …”
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YOLOv8n-SSDW: A Lightweight and Accurate Model for Barnyard Grass Detection in Fields by Yan Sun, Hanrui Guo, Xiaoan Chen, Mengqi Li, Bing Fang, Yingli Cao

“…Comprehensive performance analysis demonstrated that YOLOv8n-SSDW outperformed state-of-the-art models. …”
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Correction of Endothelial Dysfunction in Patients with Essential Hypertension when Using a Combination of Olmesartan/Lercanidipine and Zofenopril/Lercanidipine by O. V. Zimnitskaya, M. M. Petrova

“…The examination at baseline and after 7 months included the measurement of office systolic (SBP) and diastolic (DBP) blood pressure, determination of sPECAM-1 levels in blood plasma by quantitative solid-phase enzyme immunoassay, electrocardiography, transthoracic echocardiography, complete clinical blood test, general urine analysis, biochemical blood test with lipid profile.Results. …”
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Enhanced Interactive Interior Spaces for Safe Design in Administrative Office Buildings by Shatha Abd Abd Ali, Faten Abbas Lafta

“… Safe design is not limited to physical protection such as fire resistance or security against theft, but rather extends to include psychological safety and the general well-being of workers. Interactive interior spaces become effective tools for enhancing safety, by providing smart solutions that contribute to improving the quality of life within work environments. …”
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Urinary Clusterin is a Biomarker of Renal Epithelial Senescence and Predicts Human Kidney Disease Progression by David P. Baird, Maximilian Reck, Ross Campbell, Marie-Helena Docherty, Piotr P. Janas, Tilly Mason, Zenuida Mortuza, Matthieu Vermeren, Andy Nam, Wei Yang, Nathan Schurman, Claire Williams, Jamie P. Traynor, Patrick B. Mark, Katie J. Mylonas, Jeremy Hughes, Laura Denby, Bryan R. Conway, David A. Ferenbach

“…Urinary biomarker concentrations were quantified by ELISA (n = 322) to assess their ability to predict patient outcomes (end-stage kidney disease or > 40% renal functional loss). Results: P21+Ki67- epithelial senescence correlated with age and inversely with renal function. …”
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Selective neoadjuvant therapy of rectal cancer patients (SELREC): study protocol for a European randomised controlled, open, multicentre non-inferiority trial by Markus W Büchler, Lukas Baumann, Peter Schirmacher, Christoph W Michalski, Markus K Diener, Dirk Jäger, Pascal Probst, Mohammed Al-Saeedi, Martin Schneider, Alexis Ulrich, Constantin Schwab, Anja Sander, Christina Klose, Christoph Kahlert, Hans-Ulrich Kauczor, Jürgen Debus, Rosa Klotz, Solveig Tenckhoff, Cosima Engerer, Kristin Uzun-Lang, Caroline Wild, Bruno C Köhler

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Clinical and cost-effectiveness of individualised exercises and foot orthoses in the treatment of plantar heel pain: protocol for the TREADON randomised multi-arm multi-stage adapt... by Thomas Jaki, Melaine A Holden, Anne-Maree Keenan, Royes Joseph, Christian D Mallen, Hylton B Menz, Jesse Kigozi, Edward Roddy, Pavel Mozgunov, Martin J Thomas, Kendra Cooke, Jo Smith, Gemma Hughes, Emma Marshall, Martyn Lewis, Stephanie Butler-Walley, Simon Wathall, Laura Bowyer, June Brammar, Sarah A Lawton, Chris Drake, Thomas Burnett, Gordon J Hendry, Nadine E Foster

“…Background Plantar heel pain (PHP) is the most common soft tissue foot condition and impairs mobility, physical function, ability to work, and quality of life. Systematic reviews highlight a need for high-quality randomised controlled trials (RCTs) of exercises and orthoses for PHP. …”
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Supporting self-management of low back pain with an internet intervention in primary care: a protocol for a randomised controlled trial of clinical and cost-effectiveness (SupportB... by Beth Stuart, Paul Little, Lucy Yardley, Stephanie Hughes, Adam W A Geraghty, Elaine Hay, Gemma Mansell, Nadine E Foster, Jonathan Hill, Gareth Griffiths, Frances Webley, Lorraine Durcan, Alannah Morgan, Sarah Bathers, Stephanie Butler-Walley, Simon Wathall, Linda Leigh

“…The primary outcome is physical function (using the Roland and Morris Disability Questionnaire) over 12 months (repeated measures design). …”
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Psychotic relapse prediction via biomarker monitoring: a systematic review by Alexandros Smyrnis, Christos Theleritis, Christos Theleritis, Panagiotis Ferentinos, Nikolaos Smyrnis, Nikolaos Smyrnis

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High serum CA19-9 predicts severe cholecystitis in calculous cholecystitis patients by Shouwen Wang, Dachen Zhou, Wanjin Chen, Qi Guo, Liujin Hou, Ruolin Wu, Wei Wang, Muhammad Annus Khan, Muhammad Ahmad, Fan Huang, Meijuan Zheng, Guobin Wang, Hongchuan Zhao, Xiaoping Geng, Xiaojun Yu

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Saikosaponin-d Attenuates Irinotecan-Induced Intestinal Toxicity via TAK1/NF-&amp;kappa;B Pathway and Enhances Antitumor Efficacy by Zheng P, Ma R, Liu X, Song L, Ma B, Zou G

“…Peng Zheng,1,2,&amp;ast; Rui Ma,1,3,&amp;ast; Xiaoya Liu,2 Luda Song,3 Bing Ma,1,&amp;ast; Guijun Zou1,&amp;ast; 1Department of General Surgery, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, People’s Republic of China; 2Department of General Surgery, The Sixth Medical Center of Chinese PLA General Hospital, Beijing, 100048, People’s Republic of China; 3Medical School of Chinese PLA, Beijing, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Bing Ma, Department of General Surgery, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, People’s Republic of China, Email mabingcaowei1983@sina.com Guijun Zou, Department of General Surgery, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, People’s Republic of China, Email zougj301@163.comPurpose: Saikosaponin-d (SSD), a bioactive triterpenoid saponin derived from Bupleurum species (a traditional Chinese medicine), is recognized for its gastrointestinal protective properties. …”
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